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Entry version 116 (17 Jun 2020)
Sequence version 1 (01 Mar 2001)
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Protein
Submitted name:

Aerotaxis transducer Aer2

Gene

aer2

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi234Iron (heme 1 axial ligand); via tele nitrogenCombined sources1
Metal bindingi234Iron (heme 2 axial ligand); via tele nitrogenCombined sources1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransducerPROSITE-ProRule annotation
LigandHemeCombined sources, Iron, Metal-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
PAER208964:G1FZ6-177-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Aerotaxis transducer Aer2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:aer2Imported
Ordered Locus Names:PA0176Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri208964 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002438 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

Organism-specific databases

Pseudomonas genome database

More...
PseudoCAPi
PA0176

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9I6V6

PRoteomics IDEntifications database

More...
PRIDEi
Q9I6V6

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9I6V6

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9I6V6

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini171 – 213PASInterPro annotationAdd BLAST43
Domaini333 – 385HAMPInterPro annotationAdd BLAST53
Domaini390 – 619Methyl-accepting transducerInterPro annotationAdd BLAST230

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni405 – 425DisorderedSequence analysisAdd BLAST21
Regioni644 – 679DisorderedSequence analysisAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili41 – 68Sequence analysisAdd BLAST28
Coiled coili590 – 617Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105C8Q Bacteria
COG0840 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000445_107_1_6

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9I6V6

KEGG Orthology (KO)

More...
KOi
K03406

Identification of Orthologs from Complete Genome Data

More...
OMAi
MGRCIDE

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9I6V6

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004090 Chemotax_Me-accpt_rcpt
IPR003660 HAMP_dom
IPR041395 HAMP_N3
IPR004089 MCPsignal_dom
IPR000014 PAS
IPR035965 PAS-like_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF18575 HAMP_N3, 1 hit
PF00015 MCPsignal, 1 hit
PF13188 PAS_8, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00260 CHEMTRNSDUCR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00283 MA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55785 SSF55785, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50111 CHEMOTAXIS_TRANSDUC_2, 1 hit
PS50885 HAMP, 1 hit
PS50112 PAS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9I6V6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLFNAHAVA QQRADRIATL LQSFADGQLD TAVGEAPAPG YERLYDSLRA
60 70 80 90 100
LQRQLREQRA ELQQVESLEA GLAEMSRQHE AGWIDQTIPA ERLEGRAARI
110 120 130 140 150
AKGVNELVAA HIAVKMKVVS VVTAYGQGNF EPLMDRLPGK KAQITEAIDG
160 170 180 190 200
VRERLRGAAE ATSAQLATAA YNARIKSALD NVSANVMIAD NDLNIIYMNR
210 220 230 240 250
TVSEMLGRAE ADIRKQLPNF DAGRLMGANI DVFHKNPAHQ RHLLANLTGV
260 270 280 290 300
HKAELNLGGR RFSLDVVPVF NDANERLGSA VQWTDRTEEH RAEQEVSQLV
310 320 330 340 350
QAAAAGDFSK RVEEAGKEGF FLRLAKDLNS LVDTADRGLR DVSRMLGALA
360 370 380 390 400
QGDLTQRIEA DYQGTFGQLK DFSNDTAQSL SRMLGQIREA ADTINTAASE
410 420 430 440 450
IASGNAELSA RTEQQASSLE ETASSMEELT STVKLNAENA RQANSLAANA
460 470 480 490 500
SEVATQGGTV VQKVVSTMSS INESARKIAD IIGVIDGIAF QTNILALNAA
510 520 530 540 550
VEAARAGEQG RGFAVVAGEV RTLAQRSAAA AKEIKTLISD SVDKVENGNT
560 570 580 590 600
LVAQAGQTMS DIVVAIRRVT DIMSEIAAAS AEQSTGIEEV NSAVSQMDDM
610 620 630 640 650
TQQNAALVEE AAAAAEAMQE QAGLLNQSVA VFRLDTPPSV VQLASARPSA
660 670
PRPSAPAPLA RSGMARASKA RKEDGWEEF
Length:679
Mass (Da):72,591
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i246EF0D775120272
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG03566.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A83624

NCBI Reference Sequences

More...
RefSeqi
NP_248866.1, NC_002516.2
WP_003112650.1, NZ_QZGE01000015.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAG03566; AAG03566; PA0176

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
882219

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pae:PA0176

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|208964.12.peg.182

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG03566.1
PIRiA83624
RefSeqiNP_248866.1, NC_002516.2
WP_003112650.1, NZ_QZGE01000015.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3LNRX-ray2.64A1-172[»]
3VOLX-ray2.40A173-384[»]
4HI4X-ray2.30A/B/D/G174-289[»]
4I3MX-ray1.95A1-172[»]
4I44X-ray2.88A1-172[»]
SMRiQ9I6V6
ModBaseiSearch...
PDBe-KBiSearch...

Proteomic databases

PaxDbiQ9I6V6
PRIDEiQ9I6V6

Genome annotation databases

EnsemblBacteriaiAAG03566; AAG03566; PA0176
GeneIDi882219
KEGGipae:PA0176
PATRICifig|208964.12.peg.182

Organism-specific databases

PseudoCAPiPA0176

Phylogenomic databases

eggNOGiENOG4105C8Q Bacteria
COG0840 LUCA
HOGENOMiCLU_000445_107_1_6
InParanoidiQ9I6V6
KOiK03406
OMAiMGRCIDE
PhylomeDBiQ9I6V6

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-177-MONOMER

Miscellaneous databases

EvolutionaryTraceiQ9I6V6

Family and domain databases

InterProiView protein in InterPro
IPR004090 Chemotax_Me-accpt_rcpt
IPR003660 HAMP_dom
IPR041395 HAMP_N3
IPR004089 MCPsignal_dom
IPR000014 PAS
IPR035965 PAS-like_dom_sf
PfamiView protein in Pfam
PF18575 HAMP_N3, 1 hit
PF00015 MCPsignal, 1 hit
PF13188 PAS_8, 1 hit
PRINTSiPR00260 CHEMTRNSDUCR
SMARTiView protein in SMART
SM00283 MA, 1 hit
SUPFAMiSSF55785 SSF55785, 1 hit
PROSITEiView protein in PROSITE
PS50111 CHEMOTAXIS_TRANSDUC_2, 1 hit
PS50885 HAMP, 1 hit
PS50112 PAS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9I6V6_PSEAE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9I6V6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: June 17, 2020
This is version 116 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Reference proteomeImported
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