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Entry version 119 (17 Jun 2020)
Sequence version 1 (01 Mar 2001)
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Protein
Submitted name:

Uncharacterized protein

Gene

PA0575

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
PAER208964:G1FZ6-582-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:PA0575Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri208964 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002438 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

Organism-specific databases

Pseudomonas genome database

More...
PseudoCAPi
PA0575

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei271 – 290HelicalSequence analysisAdd BLAST20

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 22Sequence analysisAdd BLAST22
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500432707823 – 1245Sequence analysisAdd BLAST1223

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9I5W1

PRoteomics IDEntifications database

More...
PRIDEi
Q9I5W1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9I5W1

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini310 – 369PASInterPro annotationAdd BLAST60
Domaini385 – 435PACInterPro annotationAdd BLAST51
Domaini509 – 559PACInterPro annotationAdd BLAST51
Domaini560 – 635PASInterPro annotationAdd BLAST76
Domaini681 – 727PASInterPro annotationAdd BLAST47
Domaini754 – 806PACInterPro annotationAdd BLAST53
Domaini838 – 971GGDEFInterPro annotationAdd BLAST134
Domaini980 – 1234EALInterPro annotationAdd BLAST255

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili286 – 320Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105BZU Bacteria
COG0834 LUCA
COG2199 LUCA
COG2200 LUCA
COG2202 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000445_41_5_6

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9I5W1

Identification of Orthologs from Complete Genome Data

More...
OMAi
ASWPPFE

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9I5W1

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01948 EAL, 1 hit
cd01949 GGDEF, 1 hit
cd00130 PAS, 4 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.20.20.450, 1 hit
3.30.70.270, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001633 EAL_dom
IPR035919 EAL_sf
IPR000160 GGDEF_dom
IPR029787 Nucleotide_cyclase
IPR001610 PAC
IPR000014 PAS
IPR000700 PAS-assoc_C
IPR035965 PAS-like_dom_sf
IPR013655 PAS_fold_3
IPR043128 Rev_trsase/Diguanyl_cyclase
IPR001638 Solute-binding_3/MltF_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00563 EAL, 1 hit
PF00990 GGDEF, 1 hit
PF08447 PAS_3, 1 hit
PF13426 PAS_9, 3 hits
PF00497 SBP_bac_3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00052 EAL, 1 hit
SM00267 GGDEF, 1 hit
SM00086 PAC, 4 hits
SM00091 PAS, 4 hits
SM00062 PBPb, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF141868 SSF141868, 1 hit
SSF55073 SSF55073, 1 hit
SSF55785 SSF55785, 4 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00254 GGDEF, 1 hit
TIGR00229 sensory_box, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50883 EAL, 1 hit
PS50887 GGDEF, 1 hit
PS50113 PAC, 3 hits
PS50112 PAS, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9I5W1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQRLQAVLLL CLACCWPGLA GALTLTPEER AWLAEHPSIR LGMDTSWPPF
60 70 80 90 100
EYRDEQGRYQ GLAAGYIGLL QERLSVSLTP VEPKTWTQVL EQAKDGRLDL
110 120 130 140 150
LPGIMATPER QEYLSFTRPY LDFPIIILAR KNGPMPKRID ELYGLKVAVV
160 170 180 190 200
DHYAPHELLI AQHPDLTLLP LPSVAAALQA LATGQADAFV GDFASSVWNL
210 220 230 240 250
RQLKLNGLEI SGETPYRYQL AMAVPRGQPI LAGIVDKVLA DLSAGEIERL
260 270 280 290 300
QAPWVGGLLD RRPAWREMAT YGLPIVLLIL VSVAILLAMN RRLRREVSRR
310 320 330 340 350
RQLERELRDS EQHYRGLVES LNAIAWEMRL EENRFTYVSP HAERLLGYPL
360 370 380 390 400
GEWLQPGFWQ RTLHPMDAEY AIHYCMSESQ AGRDHSFDYR MLAADGRVVW
410 420 430 440 450
IRDLVTPITQ GRDLLLRGLM IDITEAKLTE QAMRLSEQKF ASVFHHCPDM
460 470 480 490 500
VVLANGADGR FLAVNSTFEQ QIGIAADDAI GKTATELGIW ALPGLGPQVL
510 520 530 540 550
EKLGHGNLTN LEVPLRRRNG STFSALLSAQ HVALDQTPAL VVVIRDITHL
560 570 580 590 600
VETQELLRIS EEKFANAFHA YPDGLLISSL EDGTLIDVNE GFTRLTGYRR
610 620 630 640 650
DEVISRSTLE LGLWVDTEDR KRLISLVRHH TLTQGFTAPV RDRNGGIRQC
660 670 680 690 700
EMSAHRISID GEDCVLTIAR DITERQLMQE KLQQAATVFE STAEGVMITD
710 720 730 740 750
TRQRITAVNR AFSEITGYSE QEALGRSPSL LSSGQHDSSF YLAMWNQLER
760 770 780 790 800
DGHWQGEIWN RRKTGELYPE WLTISAVHNP QGEITHFVGV FADISTLKYA
810 820 830 840 850
QARLDYQAHH DPLTGLPNRL LFESRLNHAL DEAREESRPG AVLFIDLDRF
860 870 880 890 900
KHINDSLGHP IGDLLLKAIA ERLRDQLRDV DTVARLGGDE FIILLPGLHQ
910 920 930 940 950
ESDAEHVARK LLNAFTAPFQ ADGHEFFVSA SVGIALFPKD GDDAPTLVKN
960 970 980 990 1000
ADAAMYRAKS RGRSRIEYYT RELTYLATER MALETELRRA LERDELQLYY
1010 1020 1030 1040 1050
QPKLSLESGL LVGAEALVRW YHPLFGEISP ERFIPLAEDC GLILPLGDWV
1060 1070 1080 1090 1100
LEHACQQMGE WQKLHAPFGP LSVNLAGAQL GQPQLIERLE QLLEQSGLEP
1110 1120 1130 1140 1150
SRLQLEITES FIMNQTEEAL AVLHGLKRLG VQLAIDDFGT GYSSLSYLKR
1160 1170 1180 1190 1200
LPLDILKIDK SFIRGLPDDP HDAAITRAII ALGRSMQLTV IAEGVETEGQ
1210 1220 1230 1240
QSFLTHEGCE QIQGFVLSPP LPAELFASKF LKPRQPIGAP REAPV
Length:1,245
Mass (Da):139,661
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF483F0AD326C0FCB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG03964.1

Protein sequence database of the Protein Information Resource

More...
PIRi
H83574

NCBI Reference Sequences

More...
RefSeqi
NP_249266.1, NC_002516.2
WP_003113216.1, NZ_QZGE01000010.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAG03964; AAG03964; PA0575

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
882126

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pae:PA0575

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|208964.12.peg.609

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG03964.1
PIRiH83574
RefSeqiNP_249266.1, NC_002516.2
WP_003113216.1, NZ_QZGE01000010.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5M3CX-ray2.80A/B809-1245[»]
SMRiQ9I5W1
ModBaseiSearch...
PDBe-KBiSearch...

Proteomic databases

PaxDbiQ9I5W1
PRIDEiQ9I5W1

Genome annotation databases

EnsemblBacteriaiAAG03964; AAG03964; PA0575
GeneIDi882126
KEGGipae:PA0575
PATRICifig|208964.12.peg.609

Organism-specific databases

PseudoCAPiPA0575

Phylogenomic databases

eggNOGiENOG4105BZU Bacteria
COG0834 LUCA
COG2199 LUCA
COG2200 LUCA
COG2202 LUCA
HOGENOMiCLU_000445_41_5_6
InParanoidiQ9I5W1
OMAiASWPPFE
PhylomeDBiQ9I5W1

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-582-MONOMER

Family and domain databases

CDDicd01948 EAL, 1 hit
cd01949 GGDEF, 1 hit
cd00130 PAS, 4 hits
Gene3Di3.20.20.450, 1 hit
3.30.70.270, 1 hit
InterProiView protein in InterPro
IPR001633 EAL_dom
IPR035919 EAL_sf
IPR000160 GGDEF_dom
IPR029787 Nucleotide_cyclase
IPR001610 PAC
IPR000014 PAS
IPR000700 PAS-assoc_C
IPR035965 PAS-like_dom_sf
IPR013655 PAS_fold_3
IPR043128 Rev_trsase/Diguanyl_cyclase
IPR001638 Solute-binding_3/MltF_N
PfamiView protein in Pfam
PF00563 EAL, 1 hit
PF00990 GGDEF, 1 hit
PF08447 PAS_3, 1 hit
PF13426 PAS_9, 3 hits
PF00497 SBP_bac_3, 1 hit
SMARTiView protein in SMART
SM00052 EAL, 1 hit
SM00267 GGDEF, 1 hit
SM00086 PAC, 4 hits
SM00091 PAS, 4 hits
SM00062 PBPb, 1 hit
SUPFAMiSSF141868 SSF141868, 1 hit
SSF55073 SSF55073, 1 hit
SSF55785 SSF55785, 4 hits
TIGRFAMsiTIGR00254 GGDEF, 1 hit
TIGR00229 sensory_box, 4 hits
PROSITEiView protein in PROSITE
PS50883 EAL, 1 hit
PS50887 GGDEF, 1 hit
PS50113 PAC, 3 hits
PS50112 PAS, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9I5W1_PSEAE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9I5W1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: June 17, 2020
This is version 119 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Reference proteomeImported
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