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UniProtKB - Q9I310 (Y1727_PSEAE)
Protein
Uncharacterized signaling protein PA1727
Gene
PA1727
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Functioni
GO - Molecular functioni
- cyclic-guanylate-specific phosphodiesterase activity Source: PseudoCAP
- diguanylate cyclase activity Source: PseudoCAP
GO - Biological processi
- cellular response to nitric oxide Source: PseudoCAP
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized signaling protein PA1727 |
Gene namesi | Ordered Locus Names:PA1727 |
Organismi | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
Taxonomic identifieri | 208964 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
Proteomesi |
|
Organism-specific databases
PseudoCAPi | PA1727 |
Subcellular locationi
Plasma membrane
- Cell membrane Curated; Multi-pass membrane protein PROSITE-ProRule annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 9 – 29 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 44 – 64 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 77 – 97 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 117 – 137 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 141 – 161 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 176 – 196 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 214 – 234 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000170474 | 1 – 685 | Uncharacterized signaling protein PA1727Add BLAST | 685 |
Proteomic databases
PaxDbi | Q9I310 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q9I310 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 199 | MHYTPROSITE-ProRule annotationAdd BLAST | 194 | |
Domaini | 293 – 425 | GGDEFPROSITE-ProRule annotationAdd BLAST | 133 | |
Domaini | 434 – 685 | EALPROSITE-ProRule annotationAdd BLAST | 252 |
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
HOGENOMi | CLU_000445_70_49_6 |
InParanoidi | Q9I310 |
OMAi | CRQMRQW |
PhylomeDBi | Q9I310 |
Family and domain databases
CDDi | cd01948, EAL, 1 hit cd01949, GGDEF, 1 hit |
Gene3Di | 3.20.20.450, 1 hit 3.30.70.270, 1 hit |
InterProi | View protein in InterPro IPR001633, EAL_dom IPR035919, EAL_sf IPR000160, GGDEF_dom IPR005330, MHYT_dom IPR029787, Nucleotide_cyclase IPR043128, Rev_trsase/Diguanyl_cyclase |
Pfami | View protein in Pfam PF00563, EAL, 1 hit PF00990, GGDEF, 1 hit PF03707, MHYT, 3 hits |
SMARTi | View protein in SMART SM00052, EAL, 1 hit SM00267, GGDEF, 1 hit |
SUPFAMi | SSF141868, SSF141868, 1 hit SSF55073, SSF55073, 1 hit |
TIGRFAMsi | TIGR00254, GGDEF, 1 hit |
PROSITEi | View protein in PROSITE PS50883, EAL, 1 hit PS50887, GGDEF, 1 hit PS50924, MHYT, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9I310-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLISSYNQVL VAFSLIVAIL ASYTALDMAG RVTLAKGREA LSWLIGGAFA
60 70 80 90 100
MGFGIWSMHF VGMLAFSLPI PLGYDLGLTL LSLLLAVGSS AFALWLVCQA
110 120 130 140 150
ELPWQRLALG ALLMGSGIAA MHYTGMAALL MMPGIVYDPL WLGLSILIAV
160 170 180 190 200
IASGAALWIA FRLRHGSRRI VLVRAGAALV MGCAIVGMHY TGMAAAQFPL
210 220 230 240 250
GSFCGAAGRG IDNGWLAVLV IVITLAVIAI ALIVSVLDSR LEARTSVLAT
260 270 280 290 300
SLARANRELI QLALHDNLTK LPNRMLLDDR LEQAIQQAIR DDRRFAVLFM
310 320 330 340 350
DLDGFKAVND AYGHHLGDLL LIEVAERIRA NVRAQDTIAR LGGDEFVLLI
360 370 380 390 400
EAREPADAAT LAEKLVKRIS QPYQISRHEV RISASIGIAL YPGDGQTRHE
410 420 430 440 450
LMINADAAMY HAKDQGRNGY CFFESSMNAN AQEQLQLLHD LRQALERRQL
460 470 480 490 500
VLHYQPKVLA PNGPMIGVEA LLRWEHPQHG LITPGQFLPL AEKTGLIVQI
510 520 530 540 550
GEWVLDEACR QMRLWLDGGH ADWNIAVNLS ALQFAHAGLV DSVRNALLRH
560 570 580 590 600
SLEPSHLILE VTESTAMRDA DASLVILEQL SAMGVGISID DFGTGYSSLL
610 620 630 640 650
YLKRLPASEL KIDRGFINEL AHDSDDAAIV SAIVALGRTL NLKIVAEGVE
660 670 680
TEAQQEFLTR LGCNSLQGFL LGRPMPAEQL LASVA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004091 Genomic DNA Translation: AAG05116.1 |
PIRi | H83428 |
RefSeqi | NP_250418.1, NC_002516.2 WP_003113558.1, NZ_QZGE01000003.1 |
Genome annotation databases
EnsemblBacteriai | AAG05116; AAG05116; PA1727 |
GeneIDi | 881914 |
KEGGi | pae:PA1727 |
PATRICi | fig|208964.12.peg.1789 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004091 Genomic DNA Translation: AAG05116.1 |
PIRi | H83428 |
RefSeqi | NP_250418.1, NC_002516.2 WP_003113558.1, NZ_QZGE01000003.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5M1T | X-ray | 2.27 | A/B | 426-685 | [»] | |
SMRi | Q9I310 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 287.DR97_160 |
Proteomic databases
PaxDbi | Q9I310 |
Genome annotation databases
EnsemblBacteriai | AAG05116; AAG05116; PA1727 |
GeneIDi | 881914 |
KEGGi | pae:PA1727 |
PATRICi | fig|208964.12.peg.1789 |
Organism-specific databases
PseudoCAPi | PA1727 |
Phylogenomic databases
HOGENOMi | CLU_000445_70_49_6 |
InParanoidi | Q9I310 |
OMAi | CRQMRQW |
PhylomeDBi | Q9I310 |
Family and domain databases
CDDi | cd01948, EAL, 1 hit cd01949, GGDEF, 1 hit |
Gene3Di | 3.20.20.450, 1 hit 3.30.70.270, 1 hit |
InterProi | View protein in InterPro IPR001633, EAL_dom IPR035919, EAL_sf IPR000160, GGDEF_dom IPR005330, MHYT_dom IPR029787, Nucleotide_cyclase IPR043128, Rev_trsase/Diguanyl_cyclase |
Pfami | View protein in Pfam PF00563, EAL, 1 hit PF00990, GGDEF, 1 hit PF03707, MHYT, 3 hits |
SMARTi | View protein in SMART SM00052, EAL, 1 hit SM00267, GGDEF, 1 hit |
SUPFAMi | SSF141868, SSF141868, 1 hit SSF55073, SSF55073, 1 hit |
TIGRFAMsi | TIGR00254, GGDEF, 1 hit |
PROSITEi | View protein in PROSITE PS50883, EAL, 1 hit PS50887, GGDEF, 1 hit PS50924, MHYT, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Y1727_PSEAE | |
Accessioni | Q9I310Primary (citable) accession number: Q9I310 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 10, 2003 |
Last sequence update: | March 1, 2001 | |
Last modified: | February 23, 2022 | |
This is version 106 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references