UniProtKB - Q9I2N2 (MODA_PSEAE)
Tungstate/molybdate/chromate-binding protein ModA
modA
Functioni
Part of the ABC transporter complex ModABC involved in the transport of molybdenum into the cell (Probable). Binds tungstate and molybdate (PubMed:31627455, PubMed:25172858).
Can also bind chromate, with lower affinity (PubMed:31627455).
Plays an essential role in recruitment of molybdate for nitrate reduction (PubMed:25172858).
1 Publication2 PublicationsSites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 60 | MolybdateBy similarity | 1 | |
Metal bindingi | 168 | Molybdate; via amide nitrogenBy similarity | 1 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- molybdate ion binding Source: InterPro
GO - Biological processi
- molybdate ion transport Source: InterPro
Keywordsi
Biological process | Transport |
Ligand | Metal-binding, Molybdenum, Tungsten |
Names & Taxonomyi
Protein namesi | Recommended name: Tungstate/molybdate/chromate-binding protein ModACurated |
Gene namesi | Name:modA1 Publication Ordered Locus Names:PA1863Imported |
Organismi | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
Taxonomic identifieri | 208964 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
Proteomesi |
|
Organism-specific databases
PseudoCAPi | PA1863 |
Subcellular locationi
Other locations
- Periplasm By similarity
Other locations
- outer membrane-bounded periplasmic space Source: GO_Central
Keywords - Cellular componenti
PeriplasmPathology & Biotechi
Disruption phenotypei
Miscellaneous databases
PHI-basei | PHI:5468 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | Sequence analysisAdd BLAST | 23 | |
ChainiPRO_5004327030 | 24 – 251 | Tungstate/molybdate/chromate-binding protein ModASequence analysisAdd BLAST | 228 |
Proteomic databases
PaxDbi | Q9I2N2 |
Interactioni
Subunit structurei
The complex is composed of two ATP-binding proteins (ModC), two transmembrane proteins (ModB) and a solute-binding protein (ModA).
By similarityProtein-protein interaction databases
STRINGi | 287.DR97_13 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
SignalPhylogenomic databases
HOGENOMi | CLU_065520_1_0_6 |
InParanoidi | Q9I2N2 |
OMAi | YGATGQF |
PhylomeDBi | Q9I2N2 |
Family and domain databases
CDDi | cd13539, PBP2_AvModA, 1 hit |
InterProi | View protein in InterPro IPR044084, AvModA-like_subst-bd IPR005950, ModA |
PIRSFi | PIRSF004846, ModA, 1 hit |
TIGRFAMsi | TIGR01256, modA, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
10 20 30 40 50
MTTRLPQLLL ALLASAVSLA ASADEVQVAV AANFTAPIQA IAKEFEKDTG
60 70 80 90 100
HRLVAAYGAT GQFYTQIKNG APFQVFLSAD DSTPAKLEQE GEVVPGSRFT
110 120 130 140 150
YAIGTLALWS PKAGYVDAEG EVLKSGSFRH LSIANPKTAP YGLAATQAMD
160 170 180 190 200
KLGLAATLGP KLVEGQNISQ AYQFVSSGNA ELGFVALSQI YKDGKVATGS
210 220 230 240 250
AWIVPTELHD PIRQDAVILN KGKDNAAAKA LVDYLKGAKA AALIKSYGYE
L
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004091 Genomic DNA Translation: AAG05252.1 |
PIRi | B83413 |
RefSeqi | NP_250554.1, NC_002516.2 WP_003113613.1, NZ_QZGE01000003.1 |
Genome annotation databases
EnsemblBacteriai | AAG05252; AAG05252; PA1863 |
GeneIDi | 877661 |
KEGGi | pae:PA1863 |
PATRICi | fig|208964.12.peg.1938 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004091 Genomic DNA Translation: AAG05252.1 |
PIRi | B83413 |
RefSeqi | NP_250554.1, NC_002516.2 WP_003113613.1, NZ_QZGE01000003.1 |
3D structure databases
SMRi | Q9I2N2 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 287.DR97_13 |
Proteomic databases
PaxDbi | Q9I2N2 |
Genome annotation databases
EnsemblBacteriai | AAG05252; AAG05252; PA1863 |
GeneIDi | 877661 |
KEGGi | pae:PA1863 |
PATRICi | fig|208964.12.peg.1938 |
Organism-specific databases
PseudoCAPi | PA1863 |
Phylogenomic databases
HOGENOMi | CLU_065520_1_0_6 |
InParanoidi | Q9I2N2 |
OMAi | YGATGQF |
PhylomeDBi | Q9I2N2 |
Miscellaneous databases
PHI-basei | PHI:5468 |
Family and domain databases
CDDi | cd13539, PBP2_AvModA, 1 hit |
InterProi | View protein in InterPro IPR044084, AvModA-like_subst-bd IPR005950, ModA |
PIRSFi | PIRSF004846, ModA, 1 hit |
TIGRFAMsi | TIGR01256, modA, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | MODA_PSEAE | |
Accessioni | Q9I2N2Primary (citable) accession number: Q9I2N2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 23, 2022 |
Last sequence update: | March 1, 2001 | |
Last modified: | February 23, 2022 | |
This is version 106 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families