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Protein

Elongation factor P

Gene

efp

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.UniRule annotation

Pathwayi: polypeptide chain elongation

This protein is involved in the pathway polypeptide chain elongation, which is part of Protein biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway polypeptide chain elongation and in Protein biosynthesis.

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-2900-MONOMER
UniPathwayi
UPA00345

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor PUniRule annotation
Short name:
EF-PUniRule annotation
Gene namesi
Name:efpUniRule annotation
Ordered Locus Names:PA2851
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA2851

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000943101 – 188Elongation factor PAdd BLAST188

Proteomic databases

PaxDbiQ9HZZ2

Interactioni

Protein-protein interaction databases

STRINGi208964.PA2851

Structurei

Secondary structure

1188
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ9HZZ2
SMRiQ9HZZ2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the elongation factor P family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DRH Bacteria
COG0231 LUCA
HOGENOMiHOG000010047
InParanoidiQ9HZZ2
KOiK02356
OMAiNTFSAGH
PhylomeDBiQ9HZZ2

Family and domain databases

CDDicd04470 S1_EF-P_repeat_1, 1 hit
cd05794 S1_EF-P_repeat_2, 1 hit
Gene3Di2.30.30.30, 1 hit
HAMAPiMF_00141 EF_P, 1 hit
InterProiView protein in InterPro
IPR015365 Elong-fact-P_C
IPR012340 NA-bd_OB-fold
IPR014722 Rib_L2_dom2
IPR020599 Transl_elong_fac_P/YeiP
IPR013185 Transl_elong_KOW-like
IPR001059 Transl_elong_P/YeiP_cen
IPR011768 Transl_elongation_fac_P
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR30053 PTHR30053, 1 hit
PfamiView protein in Pfam
PF01132 EFP, 1 hit
PF08207 EFP_N, 1 hit
PF09285 Elong-fact-P_C, 1 hit
PIRSFiPIRSF005901 EF-P, 1 hit
SMARTiView protein in SMART
SM01185 EFP, 1 hit
SM00841 Elong-fact-P_C, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF50249 SSF50249, 2 hits
TIGRFAMsiTIGR00038 efp, 1 hit

Sequencei

Sequence statusi: Complete.

Q9HZZ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKTAQEFRAG QVANINGAPW VIQKAEFNKS GRNAAVVKMK LKNLLTGAGT
60 70 80 90 100
ETVFKADDKL EPIILDRKEV TYSYFADPLY VFMDSEFNQY EIEKDDLEGV
110 120 130 140 150
LTFIEDGMTD ICEAVFYNDK VISVELPTTI VRQIAYTEPA VRGDTSGKVM
160 170 180
KTARLNNGAE LQVSAFCEIG DSIEIDTRTG EYKSRVKA
Length:188
Mass (Da):20,985
Last modified:March 1, 2001 - v1
Checksum:i245AF4EB8811CEA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG06239.1
PIRiF83290
RefSeqiNP_251541.1, NC_002516.2
WP_003090942.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG06239; AAG06239; PA2851
GeneIDi882605
KEGGipae:PA2851
PATRICifig|208964.12.peg.2991

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG06239.1
PIRiF83290
RefSeqiNP_251541.1, NC_002516.2
WP_003090942.1, NC_002516.2

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3OYYX-ray1.75A/B1-188[»]
ProteinModelPortaliQ9HZZ2
SMRiQ9HZZ2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA2851

Proteomic databases

PaxDbiQ9HZZ2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG06239; AAG06239; PA2851
GeneIDi882605
KEGGipae:PA2851
PATRICifig|208964.12.peg.2991

Organism-specific databases

PseudoCAPiPA2851

Phylogenomic databases

eggNOGiENOG4105DRH Bacteria
COG0231 LUCA
HOGENOMiHOG000010047
InParanoidiQ9HZZ2
KOiK02356
OMAiNTFSAGH
PhylomeDBiQ9HZZ2

Enzyme and pathway databases

UniPathwayi
UPA00345

BioCyciPAER208964:G1FZ6-2900-MONOMER

Family and domain databases

CDDicd04470 S1_EF-P_repeat_1, 1 hit
cd05794 S1_EF-P_repeat_2, 1 hit
Gene3Di2.30.30.30, 1 hit
HAMAPiMF_00141 EF_P, 1 hit
InterProiView protein in InterPro
IPR015365 Elong-fact-P_C
IPR012340 NA-bd_OB-fold
IPR014722 Rib_L2_dom2
IPR020599 Transl_elong_fac_P/YeiP
IPR013185 Transl_elong_KOW-like
IPR001059 Transl_elong_P/YeiP_cen
IPR011768 Transl_elongation_fac_P
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR30053 PTHR30053, 1 hit
PfamiView protein in Pfam
PF01132 EFP, 1 hit
PF08207 EFP_N, 1 hit
PF09285 Elong-fact-P_C, 1 hit
PIRSFiPIRSF005901 EF-P, 1 hit
SMARTiView protein in SMART
SM01185 EFP, 1 hit
SM00841 Elong-fact-P_C, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF50249 SSF50249, 2 hits
TIGRFAMsiTIGR00038 efp, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiEFP_PSEAE
AccessioniPrimary (citable) accession number: Q9HZZ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 6, 2003
Last sequence update: March 1, 2001
Last modified: May 23, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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