UniProtKB - Q9HXI2 (SECF_PSEAE)
Protein
Protein translocase subunit SecF
Gene
secF
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Functioni
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.UniRule annotation
GO - Molecular functioni
GO - Biological processi
- intracellular protein transmembrane transport Source: UniProtKB-UniRule
- protein targeting Source: UniProtKB-UniRule
- protein transport Source: GO_Central
- protein transport by the Sec complex Source: UniProtKB-UniRule
Keywordsi
Biological process | Protein transport, Translocation, Transport |
Enzyme and pathway databases
BioCyci | PAER208964:G1FZ6-3891-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Protein translocase subunit SecF |
Gene namesi | Name:secFUniRule annotation Ordered Locus Names:PA3820 |
Organismi | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
Taxonomic identifieri | 208964 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
Proteomesi |
|
Organism-specific databases
PseudoCAPi | PA3820 |
Subcellular locationi
- Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 17 – 37 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 134 – 154 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 158 – 178 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 185 – 205 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 232 – 254 | HelicalUniRule annotationAdd BLAST | 23 | |
Transmembranei | 268 – 288 | HelicalUniRule annotationAdd BLAST | 21 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000287814 | 1 – 306 | Protein translocase subunit SecFAdd BLAST | 306 |
Proteomic databases
PaxDbi | Q9HXI2 |
PRIDEi | Q9HXI2 |
Interactioni
Subunit structurei
Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
UniRule annotationFamily & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
HOGENOMi | CLU_050012_1_0_6 |
InParanoidi | Q9HXI2 |
OMAi | AFEWRMA |
PhylomeDBi | Q9HXI2 |
Family and domain databases
HAMAPi | MF_01464_B, SecF_B, 1 hit |
InterProi | View protein in InterPro IPR022813, SecD/SecF_arch_bac IPR022645, SecD/SecF_bac IPR022646, SecD/SecF_CS IPR005665, SecF_bac |
PANTHERi | PTHR30081, PTHR30081, 1 hit |
Pfami | View protein in Pfam PF07549, Sec_GG, 1 hit PF02355, SecD_SecF, 1 hit |
PRINTSi | PR01755, SECFTRNLCASE |
TIGRFAMsi | TIGR00916, 2A0604s01, 1 hit TIGR00966, 3a0501s07, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9HXI2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNIKIGTINF MGIRNVAFAV TLILTVIALG SWFTKGINFG LDFTGGTLIE
60 70 80 90 100
LTYEQPADLG KVRGQLVGAG YEDAVVQSFG DARDVLVRMP SEDPELGKKV
110 120 130 140 150
ATALQQADAG NPANLKRVEY VGPQVGEELR DQGGLGMLLA LGGILLYVGF
160 170 180 190 200
RFQWKFALGA ILSLVHDAII VMGVLSFFQV TFDLTVLAAV LAVVGYSLND
210 220 230 240 250
TIVIFDRVRE NFRVLRKADL VENLNISTSQ TLLRTIATSV STLLAIAALL
260 270 280 290 300
FFGGDNLFGF SIALFVGVMA GTYSSIYIAN VVLIWLNLTS EDLIPPQAKD
TVDDRP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004091 Genomic DNA Translation: AAG07207.1 |
PIRi | E83169 |
RefSeqi | NP_252509.1, NC_002516.2 WP_003100612.1, NZ_QZGE01000001.1 |
Genome annotation databases
EnsemblBacteriai | AAG07207; AAG07207; PA3820 |
GeneIDi | 879904 |
KEGGi | pae:PA3820 |
PATRICi | fig|208964.12.peg.3999 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004091 Genomic DNA Translation: AAG07207.1 |
PIRi | E83169 |
RefSeqi | NP_252509.1, NC_002516.2 WP_003100612.1, NZ_QZGE01000001.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | Q9HXI2 |
PRIDEi | Q9HXI2 |
Genome annotation databases
EnsemblBacteriai | AAG07207; AAG07207; PA3820 |
GeneIDi | 879904 |
KEGGi | pae:PA3820 |
PATRICi | fig|208964.12.peg.3999 |
Organism-specific databases
PseudoCAPi | PA3820 |
Phylogenomic databases
HOGENOMi | CLU_050012_1_0_6 |
InParanoidi | Q9HXI2 |
OMAi | AFEWRMA |
PhylomeDBi | Q9HXI2 |
Enzyme and pathway databases
BioCyci | PAER208964:G1FZ6-3891-MONOMER |
Family and domain databases
HAMAPi | MF_01464_B, SecF_B, 1 hit |
InterProi | View protein in InterPro IPR022813, SecD/SecF_arch_bac IPR022645, SecD/SecF_bac IPR022646, SecD/SecF_CS IPR005665, SecF_bac |
PANTHERi | PTHR30081, PTHR30081, 1 hit |
Pfami | View protein in Pfam PF07549, Sec_GG, 1 hit PF02355, SecD_SecF, 1 hit |
PRINTSi | PR01755, SECFTRNLCASE |
TIGRFAMsi | TIGR00916, 2A0604s01, 1 hit TIGR00966, 3a0501s07, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SECF_PSEAE | |
Accessioni | Q9HXI2Primary (citable) accession number: Q9HXI2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 15, 2007 |
Last sequence update: | March 1, 2001 | |
Last modified: | December 2, 2020 | |
This is version 106 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families