UniProtKB - Q9HXB7 (Q9HXB7_PSEAE)
Protein
Submitted name:
Probable 2-hydroxyacid dehydrogenase
Gene
PA3896
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Functioni
GO - Molecular functioni
- glyoxylate reductase (NADP) activity Source: GO_Central
- hydroxypyruvate reductase activity Source: GO_Central
- NAD binding Source: InterPro
Keywordsi
Molecular function | OxidoreductaseUniRule annotation |
Enzyme and pathway databases
BioCyci | PAER208964:G1FZ6-3969-MONOMER |
Names & Taxonomyi
Protein namesi | Submitted name: Probable 2-hydroxyacid dehydrogenaseImported |
Gene namesi | Ordered Locus Names:PA3896Imported |
Organismi | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)Imported |
Taxonomic identifieri | 208964 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
Proteomesi |
|
Organism-specific databases
PseudoCAPi | PA3896 |
Structurei
3D structure databases
ProteinModelPortali | Q9HXB7 |
SMRi | Q9HXB7 |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 5 – 318 | 2-Hacid_dhInterPro annotationAdd BLAST | 314 | |
Domaini | 108 – 286 | 2-Hacid_dh_CInterPro annotationAdd BLAST | 179 |
Sequence similaritiesi
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation
Phylogenomic databases
eggNOGi | ENOG4105C5I Bacteria COG1052 LUCA |
HOGENOMi | HOG000136700 |
InParanoidi | Q9HXB7 |
KOi | K00090 |
OMAi | NTARGKS |
PhylomeDBi | Q9HXB7 |
Family and domain databases
InterProi | View protein in InterPro IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029753 D-isomer_DH_CS IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00671 D_2_HYDROXYACID_DH_3, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9HXB7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKKNVFVFSR LAPEHLERLQ CQFNVRVLEP KQGDIDAQYA AALPDTHGMI
60 70 80 90 100
GVGRPLGARQ LEQAKQLEVI SSVSVGYDNY DLDYLNRRGI ALTNTPDVLT
110 120 130 140 150
ETTADLGFAL LISAARRVAE LDAWVKAGNW KRTVDAPQFG TDVHGKKLGI
160 170 180 190 200
LGLGRIGAAI ARRGRFGFGM QVLYHGNNRK PELEQELGAR FLGFDELLGE
210 220 230 240 250
ADFVCVVVPL GAQTRQLIGA RELGLMKPSA ILVNVARGQV VDEAALVAAL
260 270 280 290 300
REKRILGAGL DVYEKEPLAE SPLFALDNVV TLPHIGSATH ETRRAMAERA
310 320
LQNFEAALRG ERPLDLVNPQ VWRRG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004091 Genomic DNA Translation: AAG07283.1 |
PIRi | C83158 |
RefSeqi | NP_252585.1, NC_002516.2 WP_003104226.1, NC_002516.2 |
Genome annotation databases
EnsemblBacteriai | AAG07283; AAG07283; PA3896 |
GeneIDi | 879660 |
KEGGi | pae:PA3896 |
PATRICi | fig|208964.12.peg.4081 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004091 Genomic DNA Translation: AAG07283.1 |
PIRi | C83158 |
RefSeqi | NP_252585.1, NC_002516.2 WP_003104226.1, NC_002516.2 |
3D structure databases
ProteinModelPortali | Q9HXB7 |
SMRi | Q9HXB7 |
ModBasei | Search... |
MobiDBi | Search... |
Protein-protein interaction databases
STRINGi | 208964.PA3896 |
Proteomic databases
PaxDbi | Q9HXB7 |
PRIDEi | Q9HXB7 |
Protocols and materials databases
DNASUi | 879660 |
Structural Biology Knowledgebase | Search... |
Genome annotation databases
EnsemblBacteriai | AAG07283; AAG07283; PA3896 |
GeneIDi | 879660 |
KEGGi | pae:PA3896 |
PATRICi | fig|208964.12.peg.4081 |
Organism-specific databases
PseudoCAPi | PA3896 |
Phylogenomic databases
eggNOGi | ENOG4105C5I Bacteria COG1052 LUCA |
HOGENOMi | HOG000136700 |
InParanoidi | Q9HXB7 |
KOi | K00090 |
OMAi | NTARGKS |
PhylomeDBi | Q9HXB7 |
Enzyme and pathway databases
BioCyci | PAER208964:G1FZ6-3969-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029753 D-isomer_DH_CS IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00671 D_2_HYDROXYACID_DH_3, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | Q9HXB7_PSEAE | |
Accessioni | Q9HXB7Primary (citable) accession number: Q9HXB7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2001 |
Last sequence update: | March 1, 2001 | |
Last modified: | November 7, 2018 | |
This is version 107 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |