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Protein
Submitted name:

Aminoglycoside 3'-phosphotransferase type IIb

Gene

aph

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei195Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotation, Transferase
Biological processAntibiotic resistanceUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-4192-MONOMER

Names & Taxonomyi

Protein namesi
Submitted name:
Aminoglycoside 3'-phosphotransferase type IIbImported
Gene namesi
Name:aphImported
Ordered Locus Names:PA4119Imported
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)Imported
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4119

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL1075212

PTM / Processingi

Proteomic databases

PaxDbiQ9HWR2

Interactioni

Protein-protein interaction databases

STRINGi208964.PA4119

Structurei

3D structure databases

ProteinModelPortaliQ9HWR2
SMRiQ9HWR2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 259APHInterPro annotationAdd BLAST231

Sequence similaritiesi

Belongs to the aminoglycoside phosphotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R0M Bacteria
COG3231 LUCA
HOGENOMiHOG000233068
InParanoidiQ9HWR2
KOiK19300
OMAiDACAPNT

Family and domain databases

CDDicd05150 APH, 1 hit
InterProiView protein in InterPro
IPR002575 Aminoglycoside_PTrfase
IPR024165 Kan/Strep_kinase
IPR011009 Kinase-like_dom_sf
PfamiView protein in Pfam
PF01636 APH, 1 hit
PIRSFiPIRSF000706 Kanamycin_kin, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit

Sequencei

Sequence statusi: Complete.

Q9HWR2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHDAATSMPP QAPSTWADYL AGYRWRGQGE GCSAATVHRL EAARRPTLFV
60 70 80 90 100
KQEVLSAHAE LPAEIARLRW LHGAGIDCPQ VLNETQSDGR QWLLMSAVPG
110 120 130 140 150
DTLSALAQRG ELEPERLVRL VAAALRRLHD LDPAACPFDH RLERRLDTVR
160 170 180 190 200
QRVEAGLVDE ADFDDDHRGR SATELYRLLL DRRPAVEDLV VAHGDACLPN
210 220 230 240 250
LLAEGRRFSG FIDCGRLGVA DRHQDLALAA RDIEAELGAA WAEAFLVEYG
260
GDIDGERLAY FRLLDEFF
Length:268
Mass (Da):29,813
Last modified:March 1, 2001 - v1
Checksum:iE8BC65E7E803D8A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG07506.1
PIRiD83131
RefSeqiNP_252808.1, NC_002516.2
WP_003113011.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG07506; AAG07506; PA4119
GeneIDi880226
KEGGipae:PA4119
PATRICifig|208964.12.peg.4316

Similar proteinsi

Entry informationi

Entry nameiQ9HWR2_PSEAE
AccessioniPrimary (citable) accession number: Q9HWR2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: February 28, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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