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Protein

Phosphocarrier protein HPr

Gene

ptsH

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei15Pros-phosphohistidine intermediatePROSITE-ProRule annotation1

GO - Biological processi

Keywordsi

Biological processPhosphotransferase system, Sugar transport, Transport

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-4555-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphocarrier protein HPr
Alternative name(s):
Histidine-containing protein
Gene namesi
Name:ptsH
Ordered Locus Names:PA4466
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4466

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001078671 – 90Phosphocarrier protein HPrAdd BLAST90

Proteomic databases

PaxDbiQ9HVV2
PRIDEiQ9HVV2

Interactioni

Protein-protein interaction databases

STRINGi208964.PA4466

Structurei

3D structure databases

ProteinModelPortaliQ9HVV2
SMRiQ9HVV2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 89HPrPROSITE-ProRule annotationAdd BLAST89

Sequence similaritiesi

Belongs to the HPr family.Curated

Phylogenomic databases

eggNOGiENOG41080Z8 Bacteria
COG1925 LUCA
HOGENOMiHOG000278398
InParanoidiQ9HVV2
KOiK11189
OMAiAEVWVTR
PhylomeDBiQ9HVV2

Family and domain databases

CDDicd00367 PTS-HPr_like, 1 hit
Gene3Di3.30.1340.10, 1 hit
InterProiView protein in InterPro
IPR000032 HPr-like
IPR035895 HPr-like_sf
IPR001020 PTS_HPr_His_P_site
IPR002114 PTS_HPr_Ser_P_site
PfamiView protein in Pfam
PF00381 PTS-HPr, 1 hit
PRINTSiPR00107 PHOSPHOCPHPR
SUPFAMiSSF55594 SSF55594, 1 hit
TIGRFAMsiTIGR01003 PTS_HPr_family, 1 hit
PROSITEiView protein in PROSITE
PS51350 PTS_HPR_DOM, 1 hit
PS00369 PTS_HPR_HIS, 1 hit
PS00589 PTS_HPR_SER, 1 hit

Sequencei

Sequence statusi: Complete.

Q9HVV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPALEITIIN KLGLHARAAA KFVGVAGRYP CQVRVGRNPE SCVDGKSIMA
60 70 80 90
VMMLAAGKGT NLHLHTEGEQ EDEALNALVE LINNRFDEGE
Length:90
Mass (Da):9,702
Last modified:March 1, 2001 - v1
Checksum:i257E27A616D31C7A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG07854.1
PIRiB83088
RefSeqiNP_253156.1, NC_002516.2
WP_003094362.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG07854; AAG07854; PA4466
GeneIDi881011
KEGGipae:PA4466
PATRICifig|208964.12.peg.4676

Similar proteinsi

Entry informationi

Entry nameiPTHP_PSEAE
AccessioniPrimary (citable) accession number: Q9HVV2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: March 1, 2001
Last modified: May 23, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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