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Protein

5-oxoprolinase subunit A 3

Gene

pxpA3

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.UniRule annotation

Catalytic activityi

ATP + 5-oxo-L-proline + 2 H2O = ADP + phosphate + L-glutamate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-4600-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
5-oxoprolinase subunit A 3UniRule annotation (EC:3.5.2.9UniRule annotation)
Short name:
5-OPase subunit A 3UniRule annotation
Alternative name(s):
5-oxoprolinase (ATP-hydrolyzing) subunit A 3UniRule annotation
Gene namesi
Name:pxpA3UniRule annotation
Ordered Locus Names:PA4511
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4511

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001850271 – 2515-oxoprolinase subunit A 3Add BLAST251

Proteomic databases

PaxDbiQ9HVR0

Interactioni

Subunit structurei

Forms a complex composed of PxpA, PxpB and PxpC.UniRule annotation

Protein-protein interaction databases

STRINGi208964.PA4511

Structurei

Secondary structure

1251
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ9HVR0
SMRiQ9HVR0
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9HVR0

Family & Domainsi

Sequence similaritiesi

Belongs to the LamB/PxpA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105E7W Bacteria
COG1540 LUCA
HOGENOMiHOG000237330
InParanoidiQ9HVR0
KOiK07160
OMAiVNIACGF
PhylomeDBiQ9HVR0

Family and domain databases

HAMAPiMF_00691 PxpA, 1 hit
InterProiView protein in InterPro
IPR011330 Glyco_hydro/deAcase_b/a-brl
IPR005501 UPF0271_LamB_YcsF_PxpA
PANTHERiPTHR30292 PTHR30292, 1 hit
PfamiView protein in Pfam
PF03746 LamB_YcsF, 1 hit
SUPFAMiSSF88713 SSF88713, 1 hit

Sequencei

Sequence statusi: Complete.

Q9HVR0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNDTGRRILL NCDMGESFGA WRMGDDVHSM PLVDQANLAC GFHAGDPLTM
60 70 80 90 100
RRAVELAVRH GVSIGAHPAY PDLSGFGRRS LACSAEEVHA MVLYQIGALD
110 120 130 140 150
AFCRSLGTQV AYVKPHGALY NDLVGDDELL RAVLDACAAY RKGLPLMVLA
160 170 180 190 200
LADNGRELEL ADEADVPLLF EAFADRAYLP DGRLAPRRLG GAVHHDPQRI
210 220 230 240 250
IEQALAIARG EAFPDYDGNP LRLTADSLCV HGDNPQSLAV LRRLRAALDS

L
Length:251
Mass (Da):27,166
Last modified:March 1, 2001 - v1
Checksum:iE1AF77EEE2EB4655
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG07899.1
PIRiC83083
RefSeqiNP_253201.1, NC_002516.2
WP_003112852.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG07899; AAG07899; PA4511
GeneIDi881154
KEGGipae:PA4511
PATRICifig|208964.12.peg.4721

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG07899.1
PIRiC83083
RefSeqiNP_253201.1, NC_002516.2
WP_003112852.1, NC_002516.2

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2XU2X-ray2.30A2-251[»]
ProteinModelPortaliQ9HVR0
SMRiQ9HVR0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA4511

Proteomic databases

PaxDbiQ9HVR0

Protocols and materials databases

DNASUi881154
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG07899; AAG07899; PA4511
GeneIDi881154
KEGGipae:PA4511
PATRICifig|208964.12.peg.4721

Organism-specific databases

PseudoCAPiPA4511

Phylogenomic databases

eggNOGiENOG4105E7W Bacteria
COG1540 LUCA
HOGENOMiHOG000237330
InParanoidiQ9HVR0
KOiK07160
OMAiVNIACGF
PhylomeDBiQ9HVR0

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-4600-MONOMER

Miscellaneous databases

EvolutionaryTraceiQ9HVR0

Family and domain databases

HAMAPiMF_00691 PxpA, 1 hit
InterProiView protein in InterPro
IPR011330 Glyco_hydro/deAcase_b/a-brl
IPR005501 UPF0271_LamB_YcsF_PxpA
PANTHERiPTHR30292 PTHR30292, 1 hit
PfamiView protein in Pfam
PF03746 LamB_YcsF, 1 hit
SUPFAMiSSF88713 SSF88713, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPXPA3_PSEAE
AccessioniPrimary (citable) accession number: Q9HVR0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 4, 2003
Last sequence update: March 1, 2001
Last modified: July 18, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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