UniProtKB - Q9HT95 (ATSE4_PSEAE)
Protein
Acetyltransferase PA5475
Gene
PA5475
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Functioni
Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It prefers the antibiotic chloramphenicol.1 Publication
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 125 | Coenzyme A; via amide nitrogenBy similarity | 1 | |
Binding sitei | 156 | Coenzyme ABy similarity | 1 |
GO - Molecular functioni
- N-acetyltransferase activity Source: InterPro
- transferase activity, transferring acyl groups other than amino-acyl groups Source: UniProtKB
Keywordsi
Molecular function | Acyltransferase, Transferase |
Enzyme and pathway databases
BioCyci | PAER208964:G1FZ6-5603-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Acetyltransferase PA54751 Publication (EC:2.3.1.-)Alternative name(s): GCN5-related N-acetyltransferase1 Publication Short name: GNAT1 Publication |
Gene namesi | Ordered Locus Names:PA5475 |
Organismi | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
Taxonomic identifieri | 208964 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
Proteomesi |
|
Organism-specific databases
PseudoCAPi | PA5475 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000433350 | 1 – 186 | Acetyltransferase PA5475Add BLAST | 186 |
Proteomic databases
PaxDbi | Q9HT95 |
PRIDEi | Q9HT95 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 31 – 186 | N-acetyltransferasePROSITE-ProRule annotationAdd BLAST | 156 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 117 – 119 | Coenzyme A bindingBy similarity | 3 | |
Regioni | 161 – 163 | Coenzyme A bindingBy similarity | 3 |
Phylogenomic databases
eggNOGi | ENOG41090JX Bacteria COG0454 LUCA |
HOGENOMi | HOG000247525 |
InParanoidi | Q9HT95 |
OMAi | ECECAVT |
PhylomeDBi | Q9HT95 |
Family and domain databases
InterProi | View protein in InterPro IPR016181 Acyl_CoA_acyltransferase IPR000182 GNAT_dom |
SUPFAMi | SSF55729 SSF55729, 1 hit |
PROSITEi | View protein in PROSITE PS51186 GNAT, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9HT95-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSNVQNASRS SAFAAVEGDH WVESLDDGRH VLIRPLREED RERERQFINR
60 70 80 90 100
LSPATRHFRF LGEIKEASPA LLDQLMDIDY QQSMAFVALV HEDGELREVG
110 120 130 140 150
ISRYAACCEE GQCECAVTIA DDYQGLGLDA VLMRHLIDVA RRNGFRQMYS
160 170 180
VDSAANRAMR DLCCALGFVG QRDPDDSTQV IHRLAL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004091 Genomic DNA Translation: AAG08860.1 |
PIRi | E82961 |
RefSeqi | NP_254162.1, NC_002516.2 WP_003096934.1, NZ_QZGE01000012.1 |
Genome annotation databases
EnsemblBacteriai | AAG08860; AAG08860; PA5475 |
GeneIDi | 878199 |
KEGGi | pae:PA5475 |
PATRICi | fig|208964.12.peg.5739 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004091 Genomic DNA Translation: AAG08860.1 |
PIRi | E82961 |
RefSeqi | NP_254162.1, NC_002516.2 WP_003096934.1, NZ_QZGE01000012.1 |
3D structure databases
SMRi | Q9HT95 |
ModBasei | Search... |
Proteomic databases
PaxDbi | Q9HT95 |
PRIDEi | Q9HT95 |
Protocols and materials databases
DNASUi | 878199 |
Genome annotation databases
EnsemblBacteriai | AAG08860; AAG08860; PA5475 |
GeneIDi | 878199 |
KEGGi | pae:PA5475 |
PATRICi | fig|208964.12.peg.5739 |
Organism-specific databases
PseudoCAPi | PA5475 |
Phylogenomic databases
eggNOGi | ENOG41090JX Bacteria COG0454 LUCA |
HOGENOMi | HOG000247525 |
InParanoidi | Q9HT95 |
OMAi | ECECAVT |
PhylomeDBi | Q9HT95 |
Enzyme and pathway databases
BioCyci | PAER208964:G1FZ6-5603-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR016181 Acyl_CoA_acyltransferase IPR000182 GNAT_dom |
SUPFAMi | SSF55729 SSF55729, 1 hit |
PROSITEi | View protein in PROSITE PS51186 GNAT, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ATSE4_PSEAE | |
Accessioni | Q9HT95Primary (citable) accession number: Q9HT95 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 24, 2015 |
Last sequence update: | March 1, 2001 | |
Last modified: | October 16, 2019 | |
This is version 90 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |