UniProtKB - Q9HMA2 (Q9HMA2_HALSA)
Protein
Submitted name:
Excision nuclease chain A
Gene
uvrA
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 662 – 669 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATP binding Source: UniProtKB-UniRule
- DNA binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
- nuclease activity Source: UniProtKB-KW
GO - Biological processi
- nucleotide-excision repair Source: InterPro
Keywordsi
Molecular function | DNA-bindingARBA annotation, Excision nucleaseARBA annotation |
Biological process | DNA damage, DNA excisionARBA annotation, DNA repair |
Ligand | ATP-bindingPROSITE-ProRule annotationARBA annotation, Metal-binding, Nucleotide-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Excision nuclease chain AImportedSubmitted name: UvrABC system protein AImported |
Gene namesi | Name:uvrAImported Ordered Locus Names:VNG_2636GImported |
Organismi | Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)Imported |
Taxonomic identifieri | 64091 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Stenosarchaea group › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium › |
Proteomesi |
|
Subcellular locationi
- Cell membrane ARBA annotation; Peripheral membrane protein ARBA annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-KW
- excinuclease repair complex Source: InterPro
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 629 – 953 | ABC transporterInterPro annotationAdd BLAST | 325 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 943 – 982 | DisorderedSequence analysisAdd BLAST | 40 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 541 – 561 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 949 – 982 | PolyampholyteSequence analysisAdd BLAST | 34 |
Keywords - Domaini
Coiled coilSequence analysis, RepeatARBA annotation, Zinc-fingerARBA annotationPhylogenomic databases
HOGENOMi | CLU_001370_0_2_2 |
InParanoidi | Q9HMA2 |
OMAi | RAGEPHC |
OrthoDBi | 721at2157 |
PhylomeDBi | Q9HMA2 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR027417, P-loop_NTPase IPR004602, UvrA IPR041552, UvrA_DNA-bd IPR041102, UvrA_inter |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit PF17755, UvrA_DNA-bind, 1 hit PF17760, UvrA_inter, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 2 hits |
TIGRFAMsi | TIGR00630, uvra, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 2 hits PS50893, ABC_TRANSPORTER_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9HMA2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSEEYIEVRG AEEHNLTDLD VELPRESLNV VTGLSGSGKS SLAFETIYAE
60 70 80 90 100
GQRRYIESLS AYARNFLGQM DKPQVESVEG LSPAISIDQK NAANNPRSTV
110 120 130 140 150
GTVTELHDYL RLLYARVGTP HCPECGREVG EQSAQQMVRR IFDLPAGTKA
160 170 180 190 200
KLLAPVVRDQ KGAFEDLFED LVNEGYSRVA VDGESYDLAY DDPDLDENYD
210 220 230 240 250
HTVDVVVDRV TVTEDARSRI TDSVETALDE ADGVLKVVVP DAGPDTELGG
260 270 280 290 300
ATARSTGDLA DDAADDRLVV EFSDALACTH CGIDISEIET RSFSFNSPHG
310 320 330 340 350
ACPECEGIGN TKEVSEDLVV VDTSKPIKDV FEAWSYQRSY YRTRLDAVAA
360 370 380 390 400
HFGVSVDTPF DELDDAVQQA FLYGTSDEVV FERSTKNGTR RKEKRFEGVI
410 420 430 440 450
PNLERRYVET DSESTRDHIE TYMSVTTCPA CDGTRLKPSS RAVLVDGTPI
460 470 480 490 500
TDVNRMSIGD ALAHFEGMEA ELDARDTKIA AEILKEIRAR LGFMTEVGLE
510 520 530 540 550
YLTLDREAST LSGGESQRIR LATQIGSGLV GVLYVLDEPS IGLHQRDNDR
560 570 580 590 600
LLNTLEELRD LGNTLIVVEH DEETMRRADT VIDMGPGPGR HGGEVVANGS
610 620 630 640 650
VADVMAATDS ITGDYLAGRE QIPVPDERRD YDDTLTVTGA RQHNLRNLDV
660 670 680 690 700
DLPIGAFTAI TGVSGSGKST LMHDILYKGL AREMNDNTSV DPGDHDAIEG
710 720 730 740 750
TEHVETVRLI DQSPIGRTPR SNPATYTGIF DYIREKFAQT KLATQRGYKK
760 770 780 790 800
GRFSFNVKGG RCEACGGQGT QKIDMNFLSD VHVPCEECGG DRYNDETLDV
810 820 830 840 850
TFKGKTIADV LDMSVEEAHD FFEADSRLGR RLQLLEDVGL DYMRLGQPST
860 870 880 890 900
TLSGGEAQRV KLAEELGKQS SGDTLYLLDE PTTGLHSHDE RKLIEVLQRL
910 920 930 940 950
TDRGNTVVVI EHELDLVKNA DHVVDLGPEG GAAGGDVVAT GTPEAVARTD
960 970 980
DSHTGRYLRD KLPAVDREGP RSGREKPALS DD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004437 Genomic DNA Translation: AAG20669.1 BK010829 Genomic DNA Translation: DAC79436.1 |
PIRi | A84413 |
RefSeqi | WP_010903972.1, NC_002607.1 |
Genome annotation databases
EnsemblBacteriai | AAG20669; AAG20669; VNG_2636G |
GeneIDi | 5953475 |
KEGGi | hal:VNG_2636G |
PATRICi | fig|64091.14.peg.2044 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004437 Genomic DNA Translation: AAG20669.1 BK010829 Genomic DNA Translation: DAC79436.1 |
PIRi | A84413 |
RefSeqi | WP_010903972.1, NC_002607.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | Q9HMA2 |
Genome annotation databases
EnsemblBacteriai | AAG20669; AAG20669; VNG_2636G |
GeneIDi | 5953475 |
KEGGi | hal:VNG_2636G |
PATRICi | fig|64091.14.peg.2044 |
Phylogenomic databases
HOGENOMi | CLU_001370_0_2_2 |
InParanoidi | Q9HMA2 |
OMAi | RAGEPHC |
OrthoDBi | 721at2157 |
PhylomeDBi | Q9HMA2 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR027417, P-loop_NTPase IPR004602, UvrA IPR041552, UvrA_DNA-bd IPR041102, UvrA_inter |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit PF17755, UvrA_DNA-bind, 1 hit PF17760, UvrA_inter, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 2 hits |
TIGRFAMsi | TIGR00630, uvra, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 2 hits PS50893, ABC_TRANSPORTER_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9HMA2_HALSA | |
Accessioni | Q9HMA2Primary (citable) accession number: Q9HMA2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2001 |
Last sequence update: | March 1, 2001 | |
Last modified: | February 10, 2021 | |
This is version 128 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |