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Entry version 130 (16 Oct 2019)
Sequence version 2 (13 Apr 2004)
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Protein

eIF-2-alpha kinase GCN2

Gene

gcn2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2-alpha/tif211) on 'Ser-52' in response to low amino acid availability (PubMed:15611163). Plays a role as an activator of the general amino acid control (GAAC) pathway required for adapatation to amino acid starvation. Converts phosphorylated eIF-2-alpha/tif211 either to a competitive inhibitor of translation initiation factor eIF-2B, leading to a global protein synthesis repression, and thus to a reduced overall utilization of amino acids, or to a translational initiation activation of specific mRNAs, such as the transcriptional activator gcn4, and hence allowing GCN4-mediated reprogramming of amino acid biosynthetic gene expression to alleviate nutrient depletion. Binds uncharged tRNAs (By similarity).By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

The kinase activity is stimulated upon binding to uncharged tRNAs.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei585ATPPROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei772Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi562 – 570ATPPROSITE-ProRule annotation9

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, tRNA-binding
Biological processStress response, Translation regulation
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
eIF-2-alpha kinase GCN2Imported
Alternative name(s):
Serine/threonine-protein kinase gcn2By similarity (EC:2.7.11.1By similarity)
Serine/threonine-protein kinase ppk28
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:gcn2Imported
Synonyms:ppk28
ORF Names:SPBC36B7.09, SPBP18G5.01
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:SPBC36B7.09

Schizosaccharomyces pombe database

More...
PomBasei
SPBC36B7.09 gcn2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000859621 – 1576eIF-2-alpha kinase GCN2Add BLAST1576

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Autophosphorylated.By similarity

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9HGN1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9HGN1

PRoteomics IDEntifications database

More...
PRIDEi
Q9HGN1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9HGN1

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer; homodimerization is important for kinase activation by uncharged tRNAs.

Interacts (via N-terminal RWD domain) with gcn1 (via N- and C-terminus); this interaction stimulates gcn2 kinase activity in a gcn20-dependent manner in response to amino acid starvation.

Interacts (via N-terminus) with the gcn1-gcn20 complex on translating ribosomes in amino acid-starved cells; gcn1 may bind near the ribosomal A-site and promotes the transfer of uncharged tRNAs from the A-site to the tRNA-binding domain in gcn2 for its subsequent kinase activation, and hence allowing gcn4 translational activation and derepression of amino acid biosynthetic genes.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
277028, 48 interactors

STRING: functional protein association networks

More...
STRINGi
4896.SPBC36B7.09.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9HGN1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini16 – 127RWDPROSITE-ProRule annotationAdd BLAST112
Domaini235 – 511Protein kinase 1PROSITE-ProRule annotationAdd BLAST277
Domaini556 – 928Protein kinase 2PROSITE-ProRule annotationAdd BLAST373

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9HGN1

KEGG Orthology (KO)

More...
KOi
K16196

Identification of Orthologs from Complete Genome Data

More...
OMAi
GSEMIYE

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9HGN1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.10.110.10, 1 hit
3.40.50.800, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036621 Anticodon-bd_dom_sf
IPR016255 Gcn2
IPR041715 HisRS-like_core
IPR024435 HisRS-related_dom
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR006575 RWD-domain
IPR008271 Ser/Thr_kinase_AS
IPR016135 UBQ-conjugating_enzyme/RWD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12745 HGTP_anticodon2, 1 hit
PF00069 Pkinase, 3 hits
PF05773 RWD, 1 hit
PF13393 tRNA-synt_His, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF000660 Ser/Thr_PK_GCN2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00591 RWD, 1 hit
SM00220 S_TKc, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54495 SSF54495, 1 hit
SSF56112 SSF56112, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 2 hits
PS00108 PROTEIN_KINASE_ST, 1 hit
PS50908 RWD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9HGN1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDAAKRLELC KEIQENEIEA LKAIFMDDFE ELKVRNAWNV TNGHVYCIHL
60 70 80 90 100
CSRSANSKSI AKLDLCIELG RSYPYVKPVI KLQNGENVLN SQIRFLLDKL
110 120 130 140 150
DTKAKDLLGE EMIFELASIV QDYLNDWQSD LSSQFASLEE ERAVQLKHDR
160 170 180 190 200
ERAEVDLQLR LKREKDALFE EEQTLQNKIQ DELQRRSYET PQSSSKKKTN
210 220 230 240 250
SKETTSLETL PTSIYFDCSI SVRDCHDSLV TFNRVLPLYT ISHSNLSTLT
260 270 280 290 300
LVKPESKEIS LQDCVFLLRT VRISTPYWST EDGKREIQEL EYELESLKVI
310 320 330 340 350
RHDLLASIYE YQLERETRGY GWRLYVLQEY SPKFTLFSLL QTVLTLDVET
360 370 380 390 400
VRAFSNNILE GLAELHRLGI SHKSLHLDNV VLFHSGHRTF AKLMDFGFTR
410 420 430 440 450
TLRDMNASHP FNINSQSITN ILPEGLYPPE VSESSFAAAS RKTDIWCFGL
460 470 480 490 500
LVLQMLCGAH VLNKFSSLKL IMTHVIPLLP GSYQDLVRRC LMRDSRKRPS
510 520 530 540 550
AIDLLSSHVI RLGTAVLPPV EQGTFSKSAR PSYGGQQDGI IDLLYRKSVS
560 570 580 590 600
RYETDFEELE FLGRGGFGEV VKVKNRIDGR FYAVKKLVLL SDDKENSRIL
610 620 630 640 650
REVMTLSRLH HEHVVRYYTA WVETEANDTV TEIISSDSES LSQSLNMAVD
660 670 680 690 700
FRQSSSLPAD KLSSLDIHFE DDYNSSADEE DPEASDISFQ YSNTSDKEGS
710 720 730 740 750
SDKDSSIEEA SSVKTQENGL NATLYIQMEY CEKLSLQDII RDKIPVDEMW
760 770 780 790 800
RLFRQILEAL AYIHSRGMMH RDLKPGNIFL DENRNVKLGD FGLATENENY
810 820 830 840 850
QDNNDKWKNR QSADEDLTTG VGTALYVAPE LLSRRNGVRY DAKVDMYSLG
860 870 880 890 900
IILFEMCMTF STSMERIRII DTIRSPSISF PSTFPFSRAS HEFKVIHCLL
910 920 930 940 950
QHDPTKRPSS QELLESEAIP PKVGEEFIQE GLRLLSNPNT PYYLKLLKVL
960 970 980 990 1000
FGQVPDRHKD FTYDFNLSEE SGVLSKVSDR GWDSLLACLV RDHVVKVFRR
1010 1020 1030 1040 1050
HGAKERESHI LFPKSSQYDK DQASVSLLDK NGTLLQLPYD TVLPYARNVA
1060 1070 1080 1090 1100
RNAVEEEKTY LISDVFREAK GGGRPKAIKE ISFDITTNSD NLDWYDAETI
1110 1120 1130 1140 1150
KALDEVLTEI PSLTESCILI NHADILSSIL DYLQVSKDKR RMATHILGQI
1160 1170 1180 1190 1200
NQRLTLSQVR NQLRIESLVP STTLDDLSLF DFRENYEEGA SKLRKIFGKE
1210 1220 1230 1240 1250
MPQKMRTALN YMERVVKLLR ALKISHQLYF MPLCVYNFEF YDGGLMFQAI
1260 1270 1280 1290 1300
NLAEKSELIC AGGRYDKLVR FFDPPLMRTA RKKHVVGICF ALEKLVFSML
1310 1320 1330 1340 1350
RYIRFHNSKQ SSKHSPSPTL KSVGPWAPRR VDVLVTSIGK DSILEKCSLL
1360 1370 1380 1390 1400
QELWALNIQA DIVLRGASSL EEIVTHYRSE GINWVLVVRQ KNTQMEHSVK
1410 1420 1430 1440 1450
ARNILKNEDD EIRFDEVGMW LLGEINERKR NESMLQSKRI LDSAQQDVAK
1460 1470 1480 1490 1500
FVDTSQSNLD VQLISLKDVN DRKYKWKHKQ NAMNKVYDLV QSAIRESSED
1510 1520 1530 1540 1550
AIALAVDCDS EAMEKLRSTT TLDEESWKRL IESCPASQRE YMQRLQKKLV
1560 1570
TLAEQDKKRV WICSFRTNEI YLYGLK
Length:1,576
Mass (Da):181,193
Last modified:April 13, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i97A97E1025C37087
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY705913 mRNA Translation: AAU11313.1
CU329671 Genomic DNA Translation: CAC05730.1

NCBI Reference Sequences

More...
RefSeqi
NP_595991.2, NM_001021898.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPBC36B7.09.1; SPBC36B7.09.1:pep; SPBC36B7.09

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2540500

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPBC36B7.09

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY705913 mRNA Translation: AAU11313.1
CU329671 Genomic DNA Translation: CAC05730.1
RefSeqiNP_595991.2, NM_001021898.2

3D structure databases

SMRiQ9HGN1
ModBaseiSearch...

Protein-protein interaction databases

BioGridi277028, 48 interactors
STRINGi4896.SPBC36B7.09.1

PTM databases

iPTMnetiQ9HGN1

Proteomic databases

MaxQBiQ9HGN1
PaxDbiQ9HGN1
PRIDEiQ9HGN1

Genome annotation databases

EnsemblFungiiSPBC36B7.09.1; SPBC36B7.09.1:pep; SPBC36B7.09
GeneIDi2540500
KEGGispo:SPBC36B7.09

Organism-specific databases

EuPathDBiFungiDB:SPBC36B7.09
PomBaseiSPBC36B7.09 gcn2

Phylogenomic databases

InParanoidiQ9HGN1
KOiK16196
OMAiGSEMIYE
PhylomeDBiQ9HGN1

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9HGN1

Family and domain databases

Gene3Di3.10.110.10, 1 hit
3.40.50.800, 1 hit
InterProiView protein in InterPro
IPR036621 Anticodon-bd_dom_sf
IPR016255 Gcn2
IPR041715 HisRS-like_core
IPR024435 HisRS-related_dom
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR006575 RWD-domain
IPR008271 Ser/Thr_kinase_AS
IPR016135 UBQ-conjugating_enzyme/RWD
PfamiView protein in Pfam
PF12745 HGTP_anticodon2, 1 hit
PF00069 Pkinase, 3 hits
PF05773 RWD, 1 hit
PF13393 tRNA-synt_His, 1 hit
PIRSFiPIRSF000660 Ser/Thr_PK_GCN2, 1 hit
SMARTiView protein in SMART
SM00591 RWD, 1 hit
SM00220 S_TKc, 2 hits
SUPFAMiSSF54495 SSF54495, 1 hit
SSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 2 hits
PS00108 PROTEIN_KINASE_ST, 1 hit
PS50908 RWD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGCN2_SCHPO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9HGN1
Secondary accession number(s): Q66T01, Q9HDW2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: April 13, 2004
Last modified: October 16, 2019
This is version 130 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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