UniProtKB - Q9HGL3 (SUM2_SCHPO)
Protein
Protein sum2
Gene
sum2
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
Required for G2/M phase checkpoint control.
GO - Molecular functioni
- mRNA binding Source: GO_Central
GO - Biological processi
- cell cycle Source: UniProtKB-KW
- negative regulation of cytoplasmic translational initiation Source: PomBase
- P-body assembly Source: PomBase
- stress granule assembly Source: GO_Central
Keywordsi
Biological process | Cell cycle |
Names & Taxonomyi
Protein namesi | Recommended name: Protein sum2 |
Gene namesi | Name:sum2 ORF Names:SPBC800.09 |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPBC800.09, sum2 |
VEuPathDBi | FungiDB:SPBC800.09 |
Subcellular locationi
Other locations
- cytoplasm Source: PomBase
- messenger ribonucleoprotein complex Source: GO_Central
- P-body Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000072312 | 1 – 426 | Protein sum2Add BLAST | 426 |
Proteomic databases
MaxQBi | Q9HGL3 |
PaxDbi | Q9HGL3 |
PRIDEi | Q9HGL3 |
PTM databases
iPTMneti | Q9HGL3 |
Interactioni
Binary interactionsi
Q9HGL3
With | #Exp. | IntAct |
---|---|---|
dcp2 [O13828] | 4 | EBI-1117052,EBI-3647323 |
Protein-protein interaction databases
BioGRIDi | 277347, 184 interactors |
IntActi | Q9HGL3, 2 interactors |
MINTi | Q9HGL3 |
STRINGi | 4896.SPBC800.09.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 296 – 332 | DFDFPROSITE-ProRule annotationAdd BLAST | 37 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 335 – 351 | FFD boxAdd BLAST | 17 | |
Motifi | 360 – 380 | TFG boxAdd BLAST | 21 |
Phylogenomic databases
eggNOGi | KOG1073, Eukaryota |
HOGENOMi | CLU_019221_4_1_1 |
InParanoidi | Q9HGL3 |
OMAi | HPRWSPY |
Family and domain databases
CDDi | cd01736, LSm14_N, 1 hit |
InterProi | View protein in InterPro IPR025762, DFDF IPR019050, FDF_dom IPR025761, FFD_box IPR025609, Lsm14-like_N IPR010920, LSM_dom_sf IPR025768, TFG_box |
Pfami | View protein in Pfam PF12701, LSM14, 1 hit |
SMARTi | View protein in SMART SM01199, FDF, 1 hit SM01271, LSM14, 1 hit |
SUPFAMi | SSF50182, SSF50182, 1 hit |
PROSITEi | View protein in PROSITE PS51512, DFDF, 1 hit PS51513, FFD, 1 hit PS51536, TFG, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9HGL3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTEFIGSRIS LISKSDIRYV GILQDINSQD STLALKHVRW CGTEGRKQDP
60 70 80 90 100
SQEIPPSDNV FDYIVFRGSD VKDLRIEEPA TTPSAPPVQP PNDPAIIGSN
110 120 130 140 150
SGQYNWNQAQ TAQPPQPVQP NPYGAPYQQA PPAGAPYYMY PNAPAQFVPP
160 170 180 190 200
GGLPLGTPLD ASTPAVPYYG APDQQQMGQR PEFAQNVSQG FAGQAPYNVR
210 220 230 240 250
PGYGMPSNQK PPNFAPGMPA PGPTAVSASP SLQSMPPTNG VIPGAQPSIE
260 270 280 290 300
ASIEKESTSI RNSTVTNDRV VNTTVDVSQS QTVETSGPSK EVPTTQPDAS
310 320 330 340 350
AAKPRTEFDF QTANQKFQSM KDDLLKGKND EEAEEFYKPK QSFFDNISCE
360 370 380 390 400
SKEKGMEAAD RRALRDRERS LNMETFGVAG SGNRGRRGRG RGRGGRGRGR
410 420
GYARNQYNQY RNSNGSQPRA QPANDQ
Sequence cautioni
The sequence BAA13831 differs from that shown. Reason: Frameshift.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 34 | A → V in BAA13831 (PubMed:9501991).Curated | 1 | |
Sequence conflicti | 308 | F → L in BAA13831 (PubMed:9501991).Curated | 1 | |
Sequence conflicti | 337 | Y → H in BAA13831 (PubMed:9501991).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D89169 mRNA Translation: BAA13831.1 Frameshift. CU329671 Genomic DNA Translation: CAC01524.1 |
PIRi | T42532 |
RefSeqi | NP_595110.1, NM_001021017.2 |
Genome annotation databases
EnsemblFungii | SPBC800.09.1; SPBC800.09.1:pep; SPBC800.09 |
GeneIDi | 2540829 |
KEGGi | spo:SPBC800.09 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D89169 mRNA Translation: BAA13831.1 Frameshift. CU329671 Genomic DNA Translation: CAC01524.1 |
PIRi | T42532 |
RefSeqi | NP_595110.1, NM_001021017.2 |
3D structure databases
SMRi | Q9HGL3 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 277347, 184 interactors |
IntActi | Q9HGL3, 2 interactors |
MINTi | Q9HGL3 |
STRINGi | 4896.SPBC800.09.1 |
PTM databases
iPTMneti | Q9HGL3 |
Proteomic databases
MaxQBi | Q9HGL3 |
PaxDbi | Q9HGL3 |
PRIDEi | Q9HGL3 |
Genome annotation databases
EnsemblFungii | SPBC800.09.1; SPBC800.09.1:pep; SPBC800.09 |
GeneIDi | 2540829 |
KEGGi | spo:SPBC800.09 |
Organism-specific databases
PomBasei | SPBC800.09, sum2 |
VEuPathDBi | FungiDB:SPBC800.09 |
Phylogenomic databases
eggNOGi | KOG1073, Eukaryota |
HOGENOMi | CLU_019221_4_1_1 |
InParanoidi | Q9HGL3 |
OMAi | HPRWSPY |
Miscellaneous databases
PROi | PR:Q9HGL3 |
Family and domain databases
CDDi | cd01736, LSm14_N, 1 hit |
InterProi | View protein in InterPro IPR025762, DFDF IPR019050, FDF_dom IPR025761, FFD_box IPR025609, Lsm14-like_N IPR010920, LSM_dom_sf IPR025768, TFG_box |
Pfami | View protein in Pfam PF12701, LSM14, 1 hit |
SMARTi | View protein in SMART SM01199, FDF, 1 hit SM01271, LSM14, 1 hit |
SUPFAMi | SSF50182, SSF50182, 1 hit |
PROSITEi | View protein in PROSITE PS51512, DFDF, 1 hit PS51513, FFD, 1 hit PS51536, TFG, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SUM2_SCHPO | |
Accessioni | Q9HGL3Primary (citable) accession number: Q9HGL3 Secondary accession number(s): P78821 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2003 |
Last sequence update: | March 1, 2001 | |
Last modified: | April 7, 2021 | |
This is version 115 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names