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UniProtKB - Q9HGL3 (SUM2_SCHPO)

Entry version 115 (07 Apr 2021)
Sequence version 1 (01 Mar 2001)
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Protein

Protein sum2

Gene

sum2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for G2/M phase checkpoint control.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • mRNA binding Source: GO_Central
Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein sum2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sum2
ORF Names:SPBC800.09
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

Schizosaccharomyces pombe database

More...PomBasei		SPBC800.09, sum2

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		FungiDB:SPBC800.09

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000723121 – 426Protein sum2Add BLAST426

Proteomic databases

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9HGL3

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9HGL3

PRoteomics IDEntifications database

More...PRIDEi		Q9HGL3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9HGL3

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		277347, 184 interactors

Protein interaction database and analysis system

More...IntActi		Q9HGL3, 2 interactors

Molecular INTeraction database

More...MINTi		Q9HGL3

STRING: functional protein association networks

More...STRINGi		4896.SPBC800.09.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9HGL3

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini296 – 332DFDFPROSITE-ProRule annotationAdd BLAST37

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi335 – 351FFD boxAdd BLAST17
Motifi360 – 380TFG boxAdd BLAST21

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1073, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_019221_4_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9HGL3

Identification of Orthologs from Complete Genome Data

More...OMAi		HPRWSPY

Family and domain databases

Conserved Domains Database

More...CDDi		cd01736, LSm14_N, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR025762, DFDF
IPR019050, FDF_dom
IPR025761, FFD_box
IPR025609, Lsm14-like_N
IPR010920, LSM_dom_sf
IPR025768, TFG_box

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12701, LSM14, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01199, FDF, 1 hit
SM01271, LSM14, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50182, SSF50182, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51512, DFDF, 1 hit
PS51513, FFD, 1 hit
PS51536, TFG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9HGL3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTEFIGSRIS LISKSDIRYV GILQDINSQD STLALKHVRW CGTEGRKQDP 
        60         70         80         90        100
SQEIPPSDNV FDYIVFRGSD VKDLRIEEPA TTPSAPPVQP PNDPAIIGSN 
       110        120        130        140        150
SGQYNWNQAQ TAQPPQPVQP NPYGAPYQQA PPAGAPYYMY PNAPAQFVPP 
       160        170        180        190        200
GGLPLGTPLD ASTPAVPYYG APDQQQMGQR PEFAQNVSQG FAGQAPYNVR 
       210        220        230        240        250
PGYGMPSNQK PPNFAPGMPA PGPTAVSASP SLQSMPPTNG VIPGAQPSIE 
       260        270        280        290        300
ASIEKESTSI RNSTVTNDRV VNTTVDVSQS QTVETSGPSK EVPTTQPDAS 
       310        320        330        340        350
AAKPRTEFDF QTANQKFQSM KDDLLKGKND EEAEEFYKPK QSFFDNISCE 
       360        370        380        390        400
SKEKGMEAAD RRALRDRERS LNMETFGVAG SGNRGRRGRG RGRGGRGRGR 
       410        420 
GYARNQYNQY RNSNGSQPRA QPANDQ
Length:426
Mass (Da):46,225
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3E97B4263D2FAF4D
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA13831 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti34A → V in BAA13831 (PubMed:9501991).Curated1
Sequence conflicti308F → L in BAA13831 (PubMed:9501991).Curated1
Sequence conflicti337Y → H in BAA13831 (PubMed:9501991).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
D89169 mRNA Translation: BAA13831.1 Frameshift.
CU329671 Genomic DNA Translation: CAC01524.1

Protein sequence database of the Protein Information Resource

More...PIRi		T42532

NCBI Reference Sequences

More...RefSeqi		NP_595110.1, NM_001021017.2

Genome annotation databases

Ensembl fungal genome annotation project

More...EnsemblFungii		SPBC800.09.1; SPBC800.09.1:pep; SPBC800.09

Database of genes from NCBI RefSeq genomes

More...GeneIDi		2540829

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		spo:SPBC800.09

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D89169 mRNA Translation: BAA13831.1 Frameshift.
CU329671 Genomic DNA Translation: CAC01524.1
PIRiT42532
RefSeqiNP_595110.1, NM_001021017.2

3D structure databases

SMRiQ9HGL3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi277347, 184 interactors
IntActiQ9HGL3, 2 interactors
MINTiQ9HGL3
STRINGi4896.SPBC800.09.1

PTM databases

iPTMnetiQ9HGL3

Proteomic databases

MaxQBiQ9HGL3
PaxDbiQ9HGL3
PRIDEiQ9HGL3

Genome annotation databases

EnsemblFungiiSPBC800.09.1; SPBC800.09.1:pep; SPBC800.09
GeneIDi2540829
KEGGispo:SPBC800.09

Organism-specific databases

PomBaseiSPBC800.09, sum2
VEuPathDBiFungiDB:SPBC800.09

Phylogenomic databases

eggNOGiKOG1073, Eukaryota
HOGENOMiCLU_019221_4_1_1
InParanoidiQ9HGL3
OMAiHPRWSPY

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q9HGL3

Family and domain databases

CDDicd01736, LSm14_N, 1 hit
InterProiView protein in InterPro
IPR025762, DFDF
IPR019050, FDF_dom
IPR025761, FFD_box
IPR025609, Lsm14-like_N
IPR010920, LSM_dom_sf
IPR025768, TFG_box
PfamiView protein in Pfam
PF12701, LSM14, 1 hit
SMARTiView protein in SMART
SM01199, FDF, 1 hit
SM01271, LSM14, 1 hit
SUPFAMiSSF50182, SSF50182, 1 hit
PROSITEiView protein in PROSITE
PS51512, DFDF, 1 hit
PS51513, FFD, 1 hit
PS51536, TFG, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSUM2_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9HGL3
Secondary accession number(s): P78821
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2003
Last sequence update: March 1, 2001
Last modified: April 7, 2021
This is version 115 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
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