UniProtKB - Q9HE11 (UTP5_SCHPO)
Protein
U3 small nucleolar RNA-associated protein 5
Gene
utp5
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs) (By similarity).By similarity
GO - Molecular functioni
- snoRNA binding Source: PomBase
GO - Biological processi
- maturation of SSU-rRNA Source: PomBase
Keywordsi
Molecular function | Ribonucleoprotein |
Biological process | Ribosome biogenesis, rRNA processing, Transcription |
Enzyme and pathway databases
Reactomei | R-SPO-6791226, Major pathway of rRNA processing in the nucleolus and cytosol |
Names & Taxonomyi
Protein namesi | Recommended name: U3 small nucleolar RNA-associated protein 5Short name: U3 snoRNA-associated protein 5 Alternative name(s): U3 protein 5 required for transcription |
Gene namesi | Name:utp5 ORF Names:SPAC20H4.01, SPAC631.03 |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPAC20H4.01, utp5 |
VEuPathDBi | FungiDB:SPAC20H4.01 |
Subcellular locationi
Nucleus
- nucleolus 1 Publication
Cytosol
- cytosol Source: PomBase
Nucleus
- nucleus Source: PomBase
- t-UTP complex Source: PomBase
Other locations
- small-subunit processome Source: PomBase
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000116824 | 1 – 666 | U3 small nucleolar RNA-associated protein 5Add BLAST | 666 |
Proteomic databases
MaxQBi | Q9HE11 |
PaxDbi | Q9HE11 |
PTM databases
iPTMneti | Q9HE11 |
Interactioni
Subunit structurei
Component of the ribosomal small subunit (SSU) processome.
By similarityProtein-protein interaction databases
BioGRIDi | 279810, 2 interactors |
STRINGi | 4896.SPAC20H4.01.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 14 – 56 | WD 1Add BLAST | 43 | |
Repeati | 60 – 114 | WD 2Add BLAST | 55 | |
Repeati | 201 – 246 | WD 3Add BLAST | 46 | |
Repeati | 259 – 301 | WD 4Add BLAST | 43 | |
Repeati | 316 – 362 | WD 5Add BLAST | 47 | |
Repeati | 495 – 535 | WD 6Add BLAST | 41 | |
Repeati | 570 – 609 | WD 7Add BLAST | 40 |
Sequence similaritiesi
Belongs to the UTP5 family.Curated
Keywords - Domaini
Repeat, WD repeatPhylogenomic databases
eggNOGi | KOG4547, Eukaryota |
HOGENOMi | CLU_023936_0_0_1 |
InParanoidi | Q9HE11 |
OMAi | WIRCTLI |
PhylomeDBi | Q9HE11 |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR007148, SSU_processome_Utp12 IPR015943, WD40/YVTN_repeat-like_dom_sf IPR036322, WD40_repeat_dom_sf |
Pfami | View protein in Pfam PF04003, Utp12, 1 hit |
SUPFAMi | SSF50978, SSF50978, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9HE11-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAVRSRPQLA FQTEKENGIG ITAFNETAKL YANVVEALDA QRLRIFDSVA
60 70 80 90 100
GSLKTEYILE KEKVISCIAW EQKPLYASEQ ITTDISGSGE ILVLGTNSGE
110 120 130 140 150
ILIYSEHLGS LTRTYSFGIL QKIIGAHVLA NDGFAIDITG KVVCFSVNTG
160 170 180 190 200
EVRTSFTVPS SSREFSGLYL STVFKNLALA SSHNIHIVDL NHRNPIDSLT
210 220 230 240 250
THTSMINSVV FQYLKDENKF YFGVSANQDR FINLYSKELD GTGEFPTNTV
260 270 280 290 300
KNVGALVCEN EVKMLSIAYE IENPETGVLA ALTNDGTIEM FENPWLSKLR
310 320 330 340 350
QNGTNASSLS HRRKLLTSHS TLKICFCRSR GDPPIVLESI AFESTDSLTV
360 370 380 390 400
VWKESTRTVF ETVPWRILSS QATNGLIELV RSKTRLTSKN KTVSNVYDES
410 420 430 440 450
NATISSGVMQ KDLRKTEEIG SAEAMEGEEQ EPSLAERLQN LTKLDQQAQA
460 470 480 490 500
LSTQISASTS LSTVLTQALK TNDQSLLESC FNNNNVETID TTIRRLDPSL
510 520 530 540 550
APILLDKLAE KLALRPMRAD VLMVWIRCTL ITHGGHLVLV DDLKHKLANL
560 570 580 590 600
HSILEDRASK YSSMLALQGK LDLVLSQIAF RKAGGSKDNA EDEEPISIYY
610 620 630 640 650
EGYEESMDEA SSTGDEGYSS DDSVDNEMYS DEENSSKGAF PDEENENREL
660
SEDYSGDESL ENSESE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329670 Genomic DNA Translation: CAC05485.1 |
RefSeqi | NP_593621.2, NM_001019052.3 |
Genome annotation databases
EnsemblFungii | SPAC20H4.01.1; SPAC20H4.01.1:pep; SPAC20H4.01 |
GeneIDi | 2543388 |
KEGGi | spo:SPAC20H4.01 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329670 Genomic DNA Translation: CAC05485.1 |
RefSeqi | NP_593621.2, NM_001019052.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 279810, 2 interactors |
STRINGi | 4896.SPAC20H4.01.1 |
PTM databases
iPTMneti | Q9HE11 |
Proteomic databases
MaxQBi | Q9HE11 |
PaxDbi | Q9HE11 |
Genome annotation databases
EnsemblFungii | SPAC20H4.01.1; SPAC20H4.01.1:pep; SPAC20H4.01 |
GeneIDi | 2543388 |
KEGGi | spo:SPAC20H4.01 |
Organism-specific databases
PomBasei | SPAC20H4.01, utp5 |
VEuPathDBi | FungiDB:SPAC20H4.01 |
Phylogenomic databases
eggNOGi | KOG4547, Eukaryota |
HOGENOMi | CLU_023936_0_0_1 |
InParanoidi | Q9HE11 |
OMAi | WIRCTLI |
PhylomeDBi | Q9HE11 |
Enzyme and pathway databases
Reactomei | R-SPO-6791226, Major pathway of rRNA processing in the nucleolus and cytosol |
Miscellaneous databases
PROi | PR:Q9HE11 |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR007148, SSU_processome_Utp12 IPR015943, WD40/YVTN_repeat-like_dom_sf IPR036322, WD40_repeat_dom_sf |
Pfami | View protein in Pfam PF04003, Utp12, 1 hit |
SUPFAMi | SSF50978, SSF50978, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | UTP5_SCHPO | |
Accessioni | Q9HE11Primary (citable) accession number: Q9HE11 Secondary accession number(s): Q9HGP3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 29, 2004 |
Last sequence update: | March 29, 2004 | |
Last modified: | February 10, 2021 | |
This is version 109 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names