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Entry version 154 (16 Oct 2019)
Sequence version 2 (27 Apr 2001)
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Protein

Transmembrane 9 superfamily member 3

Gene

TM9SF3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane 9 superfamily member 3
Alternative name(s):
EP70-P-iso
SM-11044-binding protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TM9SF3
Synonyms:SMBP
ORF Names:UNQ245/PRO282
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21529 TM9SF3

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9HD45

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei224 – 244HelicalSequence analysisAdd BLAST21
Transmembranei294 – 314HelicalSequence analysisAdd BLAST21
Transmembranei328 – 348HelicalSequence analysisAdd BLAST21
Transmembranei360 – 380HelicalSequence analysisAdd BLAST21
Transmembranei389 – 409HelicalSequence analysisAdd BLAST21
Transmembranei449 – 469HelicalSequence analysisAdd BLAST21
Transmembranei482 – 502HelicalSequence analysisAdd BLAST21
Transmembranei519 – 539HelicalSequence analysisAdd BLAST21
Transmembranei551 – 571HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
56889

Open Targets

More...
OpenTargetsi
ENSG00000077147

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA144596264

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9HD45

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TM9SF3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
13878808

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 28Sequence analysisAdd BLAST28
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003436929 – 589Transmembrane 9 superfamily member 3Add BLAST561

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi174N-linked (GlcNAc...) asparagine2 Publications1
Glycosylationi419N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9HD45

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9HD45

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9HD45

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9HD45

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9HD45

PeptideAtlas

More...
PeptideAtlasi
Q9HD45

PRoteomics IDEntifications database

More...
PRIDEi
Q9HD45

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
81832

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
1842

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9HD45

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9HD45

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9HD45

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000077147 Expressed in 229 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9HD45 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9HD45 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA039609

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
121219, 15 interactors

Protein interaction database and analysis system

More...
IntActi
Q9HD45, 25 interactors

Molecular INTeraction database

More...
MINTi
Q9HD45

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000360184

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1277 Eukaryota
ENOG410XSVB LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155493

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000216680

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9HD45

KEGG Orthology (KO)

More...
KOi
K17087

Identification of Orthologs from Complete Genome Data

More...
OMAi
CVIMFAI

Database of Orthologous Groups

More...
OrthoDBi
641127at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9HD45

TreeFam database of animal gene trees

More...
TreeFami
TF314271

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004240 EMP70

The PANTHER Classification System

More...
PANTHERi
PTHR10766 PTHR10766, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02990 EMP70, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9HD45-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRPLPGALGV AAAAALWLLL LLLPRTRADE HEHTYQDKEE VVLWMNTVGP
60 70 80 90 100
YHNRQETYKY FSLPFCVGSK KSISHYHETL GEALQGVELE FSGLDIKFKD
110 120 130 140 150
DVMPATYCEI DLDKEKRDAF VYAIKNHYWY QMYIDDLPIW GIVGEADENG
160 170 180 190 200
EDYYLWTYKK LEIGFNGNRI VDVNLTSEGK VKLVPNTKIQ MSYSVKWKKS
210 220 230 240 250
DVKFEDRFDK YLDPSFFQHR IHWFSIFNSF MMVIFLVGLV SMILMRTLRK
260 270 280 290 300
DYARYSKEEE MDDMDRDLGD EYGWKQVHGD VFRPSSHPLI FSSLIGSGCQ
310 320 330 340 350
IFAVSLIVII VAMIEDLYTE RGSMLSTAIF VYAATSPVNG YFGGSLYARQ
360 370 380 390 400
GGRRWIKQMF IGAFLIPAMV CGTAFFINFI AIYYHASRAI PFGTMVAVCC
410 420 430 440 450
ICFFVILPLN LVGTILGRNL SGQPNFPCRV NAVPRPIPEK KWFMEPAVIV
460 470 480 490 500
CLGGILPFGS IFIEMYFIFT SFWAYKIYYV YGFMMLVLVI LCIVTVCVTI
510 520 530 540 550
VCTYFLLNAE DYRWQWTSFL SAASTAIYVY MYSFYYYFFK TKMYGLFQTS
560 570 580
FYFGYMAVFS TALGIMCGAI GYMGTSAFVR KIYTNVKID
Length:589
Mass (Da):67,888
Last modified:April 27, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE673D547A35BC4A7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5TB53Q5TB53_HUMAN
Transmembrane 9 superfamily member
TM9SF3
253Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF67014 differs from that shown. Reason: Frameshift.Curated
The sequence AAQ89178 differs from that shown. Reason: Frameshift.Curated
The sequence BAA91362 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti15Missing in AAF67014 (Ref. 2) Curated1
Sequence conflicti191M → I in AAF98159 (Ref. 1) Curated1
Sequence conflicti210 – 218KYLDPSFFQ → NILIVLFS in AAF67014 (Ref. 2) Curated9
Sequence conflicti232M → T in BAA91362 (PubMed:14702039).Curated1
Sequence conflicti398V → R in AAQ89178 (PubMed:12975309).Curated1
Sequence conflicti547F → S in BAA91362 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF269150 mRNA Translation: AAF98159.1
AF160213 mRNA Translation: AAF67014.1 Frameshift.
AL138765 Genomic DNA No translation available.
CH471066 Genomic DNA Translation: EAW49972.1
CH471066 Genomic DNA Translation: EAW49974.1
BC136788 mRNA Translation: AAI36789.1
BC136789 mRNA Translation: AAI36790.1
AF116347 mRNA Translation: AAF21983.1
AY358819 mRNA Translation: AAQ89178.1 Frameshift.
AK000756 mRNA Translation: BAA91362.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS7450.1

NCBI Reference Sequences

More...
RefSeqi
NP_064508.3, NM_020123.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000371142; ENSP00000360184; ENSG00000077147

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
56889

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:56889

UCSC genome browser

More...
UCSCi
uc001kmm.5 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF269150 mRNA Translation: AAF98159.1
AF160213 mRNA Translation: AAF67014.1 Frameshift.
AL138765 Genomic DNA No translation available.
CH471066 Genomic DNA Translation: EAW49972.1
CH471066 Genomic DNA Translation: EAW49974.1
BC136788 mRNA Translation: AAI36789.1
BC136789 mRNA Translation: AAI36790.1
AF116347 mRNA Translation: AAF21983.1
AY358819 mRNA Translation: AAQ89178.1 Frameshift.
AK000756 mRNA Translation: BAA91362.1 Different initiation.
CCDSiCCDS7450.1
RefSeqiNP_064508.3, NM_020123.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi121219, 15 interactors
IntActiQ9HD45, 25 interactors
MINTiQ9HD45
STRINGi9606.ENSP00000360184

PTM databases

GlyConnecti1842
iPTMnetiQ9HD45
PhosphoSitePlusiQ9HD45
SwissPalmiQ9HD45

Polymorphism and mutation databases

BioMutaiTM9SF3
DMDMi13878808

Proteomic databases

EPDiQ9HD45
jPOSTiQ9HD45
MassIVEiQ9HD45
MaxQBiQ9HD45
PaxDbiQ9HD45
PeptideAtlasiQ9HD45
PRIDEiQ9HD45
ProteomicsDBi81832

Genome annotation databases

EnsembliENST00000371142; ENSP00000360184; ENSG00000077147
GeneIDi56889
KEGGihsa:56889
UCSCiuc001kmm.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
56889
DisGeNETi56889

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TM9SF3
HGNCiHGNC:21529 TM9SF3
HPAiHPA039609
neXtProtiNX_Q9HD45
OpenTargetsiENSG00000077147
PharmGKBiPA144596264

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1277 Eukaryota
ENOG410XSVB LUCA
GeneTreeiENSGT00940000155493
HOGENOMiHOG000216680
InParanoidiQ9HD45
KOiK17087
OMAiCVIMFAI
OrthoDBi641127at2759
PhylomeDBiQ9HD45
TreeFamiTF314271

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TM9SF3 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
56889
PharosiQ9HD45

Protein Ontology

More...
PROi
PR:Q9HD45

Gene expression databases

BgeeiENSG00000077147 Expressed in 229 organ(s), highest expression level in testis
ExpressionAtlasiQ9HD45 baseline and differential
GenevisibleiQ9HD45 HS

Family and domain databases

InterProiView protein in InterPro
IPR004240 EMP70
PANTHERiPTHR10766 PTHR10766, 1 hit
PfamiView protein in Pfam
PF02990 EMP70, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTM9S3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9HD45
Secondary accession number(s): Q5TB57
, Q6UWE7, Q9NWL8, Q9P0G9, Q9UHW8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: October 16, 2019
This is version 154 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
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