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Protein

Steroid receptor RNA activator 1

Gene

SRA1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.5 Publications

Miscellaneous

Appears to be the first example of a new class of functional RNAs also able to encode a protein.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • nuclear receptor transcription coactivator activity Source: GO_Central
  • steroid receptor RNA activator RNA binding Source: UniProtKB
  • transcription coactivator activity Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Receptor, Ribonucleoprotein
Biological processApoptosis, Transcription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Steroid receptor RNA activator 1
Alternative name(s):
Steroid receptor RNA activator protein
Short name:
SRAP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SRA1Imported
ORF Names:PP7684
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000213523.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:11281 SRA1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
603819 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9HD15

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
10011

GeneReviews a resource of expert-authored, peer-reviewed disease descriptions.

More...
GeneReviewsi
SRA1

MalaCards human disease database

More...
MalaCardsi
SRA1

Open Targets

More...
OpenTargetsi
ENSG00000213523

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA36110

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SRA1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74718904

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002341051 – 236Steroid receptor RNA activator 1Add BLAST236

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei60PhosphoserineCombined sources1
Modified residuei69PhosphoserineCombined sources1
Modified residuei87PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9HD15

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9HD15

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9HD15

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9HD15

PeptideAtlas

More...
PeptideAtlasi
Q9HD15

PRoteomics IDEntifications database

More...
PRIDEi
Q9HD15

ProteomicsDB human proteome resource

More...
ProteomicsDBi
81809

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9HD15

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9HD15

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up-regulated in human tumors of the breast, ovary, and uterus.3 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000213523 Expressed in 196 organ(s), highest expression level in right adrenal gland

CleanEx database of gene expression profiles

More...
CleanExi
HS_SRA1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9HD15 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9HD15 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA044598
HPA050153

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

SRA1 RNA exists in a ribonucleoprotein complex containing NCOA1. The RNA also forms a complex with PUS1 and RARG in the nucleus. Interacts with AR.By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
HDAC2Q927692EBI-727136,EBI-301821

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115329, 41 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9HD15

Protein interaction database and analysis system

More...
IntActi
Q9HD15, 11 interactors

Molecular INTeraction database

More...
MINTi
Q9HD15

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000337513

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1236
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2MGXNMR-A107-236[»]
4NBOX-ray2.81A/B106-215[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9HD15

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9HD15

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi56 – 104Pro-richSequence analysisAdd BLAST49

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SRA1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IK8X Eukaryota
ENOG4112996 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001803

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG061820

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9HD15

Identification of Orthologs from Complete Genome Data

More...
OMAi
FPVIESE

Database of Orthologous Groups

More...
OrthoDBi
1577322at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9HD15

TreeFam database of animal gene trees

More...
TreeFami
TF314789

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009917 SRA1-protein/COPII_Sec31
IPR040243 Steroid_recept_RNA_1

The PANTHER Classification System

More...
PANTHERi
PTHR18834 PTHR18834, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07304 SRA1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9HD15-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTRCPAGQAE VEMAELYVKP GNKERGWNDP PQFSYGLQTQ AGGPRRSLLT
60 70 80 90 100
KRVAAPQDGS PRVPASETSP GPPPMGPPPP SSKAPRSPPV GSGPASGVEP
110 120 130 140 150
TSFPVESEAV MEDVLRPLEQ ALEDCRGHTR KQVCDDISRR LALLQEQWAG
160 170 180 190 200
GKLSIPVKKR MALLVQELSS HRWDAADDIH RSLMVDHVTE VSQWMVGVKR
210 220 230
LIAEKRSLFS EEAANEEKSA ATAEKNHTIP GFQQAS
Length:236
Mass (Da):25,673
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9B0B60BE30ADD263
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
R4GMW4R4GMW4_HUMAN
Steroid receptor RNA activator 1
SRA1
75Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH40043 differs from that shown. Reason: Frameshift at position 29.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti12 – 13EM → RL in AF092038 (PubMed:10199399).Curated2
Sequence conflicti29D → T in AAH40043 (PubMed:15489334).Curated1
Sequence conflicti50T → I in AAG02115 (PubMed:12565891).Curated1
Sequence conflicti110V → RL in AAG02116 (PubMed:12565891).Curated1
Sequence conflicti110V → RL in AAL55868 (PubMed:15498874).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05206032Q → E. Corresponds to variant dbSNP:rs35610885Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF293024 mRNA Translation: AAG02114.1
AF293025 mRNA Translation: AAG02115.1
AF293026 mRNA Translation: AAG02116.1
AF318361 mRNA Translation: AAL55868.1
AF092038 mRNA No translation available.
BC040043 mRNA Translation: AAH40043.2 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34245.1

NCBI Reference Sequences

More...
RefSeqi
NP_001030312.2, NM_001035235.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.653135

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000336283; ENSP00000337513; ENSG00000213523

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10011

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10011

UCSC genome browser

More...
UCSCi
uc003lga.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF293024 mRNA Translation: AAG02114.1
AF293025 mRNA Translation: AAG02115.1
AF293026 mRNA Translation: AAG02116.1
AF318361 mRNA Translation: AAL55868.1
AF092038 mRNA No translation available.
BC040043 mRNA Translation: AAH40043.2 Frameshift.
CCDSiCCDS34245.1
RefSeqiNP_001030312.2, NM_001035235.3
UniGeneiHs.653135

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2MGXNMR-A107-236[»]
4NBOX-ray2.81A/B106-215[»]
ProteinModelPortaliQ9HD15
SMRiQ9HD15
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115329, 41 interactors
CORUMiQ9HD15
IntActiQ9HD15, 11 interactors
MINTiQ9HD15
STRINGi9606.ENSP00000337513

PTM databases

iPTMnetiQ9HD15
PhosphoSitePlusiQ9HD15

Polymorphism and mutation databases

BioMutaiSRA1
DMDMi74718904

Proteomic databases

EPDiQ9HD15
jPOSTiQ9HD15
MaxQBiQ9HD15
PaxDbiQ9HD15
PeptideAtlasiQ9HD15
PRIDEiQ9HD15
ProteomicsDBi81809

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
10011
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000336283; ENSP00000337513; ENSG00000213523
GeneIDi10011
KEGGihsa:10011
UCSCiuc003lga.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10011
DisGeNETi10011
EuPathDBiHostDB:ENSG00000213523.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SRA1
GeneReviewsiSRA1
HGNCiHGNC:11281 SRA1
HPAiHPA044598
HPA050153
MalaCardsiSRA1
MIMi603819 gene
neXtProtiNX_Q9HD15
OpenTargetsiENSG00000213523
PharmGKBiPA36110

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IK8X Eukaryota
ENOG4112996 LUCA
GeneTreeiENSGT00390000001803
HOVERGENiHBG061820
InParanoidiQ9HD15
OMAiFPVIESE
OrthoDBi1577322at2759
PhylomeDBiQ9HD15
TreeFamiTF314789

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
SRA1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
10011

Protein Ontology

More...
PROi
PR:Q9HD15

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000213523 Expressed in 196 organ(s), highest expression level in right adrenal gland
CleanExiHS_SRA1
ExpressionAtlasiQ9HD15 baseline and differential
GenevisibleiQ9HD15 HS

Family and domain databases

InterProiView protein in InterPro
IPR009917 SRA1-protein/COPII_Sec31
IPR040243 Steroid_recept_RNA_1
PANTHERiPTHR18834 PTHR18834, 1 hit
PfamiView protein in Pfam
PF07304 SRA1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSRA1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9HD15
Secondary accession number(s): Q6NVU9
, Q8IXM1, Q9HD13, Q9HD14
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: March 1, 2001
Last modified: January 16, 2019
This is version 126 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
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