Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 143 (25 May 2022)
Sequence version 2 (23 Feb 2022)
Previous versions | rss
Add a publicationFeedback
Protein

Steroid receptor RNA activator 1

Gene

SRA1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.

5 Publications

Miscellaneous

Appears to be the first example of a new class of functional RNAs also able to encode a protein.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Receptor, Ribonucleoprotein
Biological processApoptosis, Transcription, Transcription regulation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9HD15

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q9HD15

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Steroid receptor RNA activator 1Curated
Alternative name(s):
Steroid receptor RNA activator protein
Short name:
SRAP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SRA1Imported
ORF Names:PP7684
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:11281, SRA1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
603819, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9HD15

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000213523

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
10011

GeneReviews a resource of expert-authored, peer-reviewed disease descriptions.

More...
GeneReviewsi
SRA1

MalaCards human disease database

More...
MalaCardsi
SRA1

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA36110

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9HD15, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SRA1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74718904

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002341051 – 224Steroid receptor RNA activator 1Add BLAST224

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei48PhosphoserineCombined sources1
Modified residuei57PhosphoserineCombined sources1
Modified residuei75PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9HD15

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9HD15

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9HD15

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9HD15

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9HD15

PeptideAtlas

More...
PeptideAtlasi
Q9HD15

PRoteomics IDEntifications database

More...
PRIDEi
Q9HD15

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
81809

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9HD15

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9HD15

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up-regulated in human tumors of the breast, ovary, and uterus.3 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000213523, Expressed in right adrenal gland and 210 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9HD15, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9HD15, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000213523, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

SRA1 RNA exists in a ribonucleoprotein complex containing NCOA1. The RNA also forms a complex with PUS1 and RARG in the nucleus.

Interacts with AR.

By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
115329, 57 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9HD15

Protein interaction database and analysis system

More...
IntActi
Q9HD15, 12 interactors

Molecular INTeraction database

More...
MINTi
Q9HD15

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000337513

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9HD15, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...
AlphaFoldDBi
Q9HD15

Biological Magnetic Resonance Data Bank

More...
BMRBi
Q9HD15

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9HD15

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni21 – 102DisorderedSequence analysisAdd BLAST82

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi66 – 87Pro residuesSequence analysisAdd BLAST22

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SRA1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502RZ38, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_081395_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9HD15

Identification of Orthologs from Complete Genome Data

More...
OMAi
KDRGWND

Database of Orthologous Groups

More...
OrthoDBi
1577322at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9HD15

TreeFam database of animal gene trees

More...
TreeFami
TF314789

Family and domain databases

Intrinsically Disordered proteins with Extensive Annotations and Literature

More...
IDEALi
IID00683

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009917, SRA1/Sec31
IPR040243, Steroid_recept_RNA_1

The PANTHER Classification System

More...
PANTHERi
PTHR18834, PTHR18834, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07304, SRA1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9HD15-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAELYVKPGN KERGWNDPPQ FSYGLQTQAG GPRRSLLTKR VAAPQDGSPR
60 70 80 90 100
VPASETSPGP PPMGPPPPSS KAPRSPPVGS GPASGVEPTS FPVESEAVME
110 120 130 140 150
DVLRPLEQAL EDCRGHTRKQ VCDDISRRLA LLQEQWAGGK LSIPVKKRMA
160 170 180 190 200
LLVQELSSHR WDAADDIHRS LMVDHVTEVS QWMVGVKRLI AEKRSLFSEE
210 220
AANEEKSAAT AEKNHTIPGF QQAS
Length:224
Mass (Da):24,400
Last modified:February 23, 2022 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i000F380D23A9FE8F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
R4GMW4R4GMW4_HUMAN
Steroid receptor RNA activator 1
SRA1
75Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAG02114 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence AAG02115 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence AAG02116 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence AAH40043 differs from that shown. Reason: Frameshift.Curated
The sequence AAL55868 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti38T → I in AAG02115 (PubMed:12565891).Curated1
Sequence conflicti98V → RL in AAG02116 (PubMed:12565891).Curated1
Sequence conflicti98V → RL in AAL55868 (PubMed:15498874).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05206020Q → E. Corresponds to variant dbSNP:rs35610885Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF293024 mRNA Translation: AAG02114.1 Different initiation.
AF293025 mRNA Translation: AAG02115.1 Different initiation.
AF293026 mRNA Translation: AAG02116.1 Different initiation.
AF318361 mRNA Translation: AAL55868.1 Different initiation.
AF092038 mRNA No translation available.
BC040043 mRNA Translation: AAH40043.2 Frameshift.

NCBI Reference Sequences

More...
RefSeqi
NP_001030312.2, NM_001035235.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000336283.9; ENSP00000337513.6; ENSG00000213523.12

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10011

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10011

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...
MANE-Selecti
ENST00000336283.9; ENSP00000337513.6; NM_001035235.4; NP_001030312.3

UCSC genome browser

More...
UCSCi
uc003lga.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF293024 mRNA Translation: AAG02114.1 Different initiation.
AF293025 mRNA Translation: AAG02115.1 Different initiation.
AF293026 mRNA Translation: AAG02116.1 Different initiation.
AF318361 mRNA Translation: AAL55868.1 Different initiation.
AF092038 mRNA No translation available.
BC040043 mRNA Translation: AAH40043.2 Frameshift.
RefSeqiNP_001030312.2, NM_001035235.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2MGXNMR-A95-224[»]
4NBOX-ray2.81A/B94-203[»]
AlphaFoldDBiQ9HD15
BMRBiQ9HD15
SMRiQ9HD15
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi115329, 57 interactors
CORUMiQ9HD15
IntActiQ9HD15, 12 interactors
MINTiQ9HD15
STRINGi9606.ENSP00000337513

PTM databases

iPTMnetiQ9HD15
PhosphoSitePlusiQ9HD15

Genetic variation databases

BioMutaiSRA1
DMDMi74718904

Proteomic databases

EPDiQ9HD15
jPOSTiQ9HD15
MassIVEiQ9HD15
MaxQBiQ9HD15
PaxDbiQ9HD15
PeptideAtlasiQ9HD15
PRIDEiQ9HD15
ProteomicsDBi81809

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
26969, 221 antibodies from 32 providers

The DNASU plasmid repository

More...
DNASUi
10011

Genome annotation databases

EnsembliENST00000336283.9; ENSP00000337513.6; ENSG00000213523.12
GeneIDi10011
KEGGihsa:10011
MANE-SelectiENST00000336283.9; ENSP00000337513.6; NM_001035235.4; NP_001030312.3
UCSCiuc003lga.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10011
DisGeNETi10011

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SRA1
GeneReviewsiSRA1
HGNCiHGNC:11281, SRA1
HPAiENSG00000213523, Low tissue specificity
MalaCardsiSRA1
MIMi603819, gene
neXtProtiNX_Q9HD15
PharmGKBiPA36110
VEuPathDBiHostDB:ENSG00000213523

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502RZ38, Eukaryota
HOGENOMiCLU_081395_0_0_1
InParanoidiQ9HD15
OMAiKDRGWND
OrthoDBi1577322at2759
PhylomeDBiQ9HD15
TreeFamiTF314789

Enzyme and pathway databases

PathwayCommonsiQ9HD15
SignaLinkiQ9HD15

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
10011, 12 hits in 1077 CRISPR screens

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
SRA1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
10011
PharosiQ9HD15, Tbio

Protein Ontology

More...
PROi
PR:Q9HD15
RNActiQ9HD15, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000213523, Expressed in right adrenal gland and 210 other tissues
ExpressionAtlasiQ9HD15, baseline and differential
GenevisibleiQ9HD15, HS

Family and domain databases

IDEALiIID00683
InterProiView protein in InterPro
IPR009917, SRA1/Sec31
IPR040243, Steroid_recept_RNA_1
PANTHERiPTHR18834, PTHR18834, 1 hit
PfamiView protein in Pfam
PF07304, SRA1, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSRA1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9HD15
Secondary accession number(s): Q6NVU9
, Q8IXM1, Q9HD13, Q9HD14
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: February 23, 2022
Last modified: May 25, 2022
This is version 143 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again