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Protein

p53-regulated apoptosis-inducing protein 1

Gene

TP53AIP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play an important role in mediating p53/TP53-dependent apoptosis.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • apoptotic process Source: UniProtKB
  • regulation of apoptotic process Source: Reactome

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processApoptosis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
p53-regulated apoptosis-inducing protein 1
Short name:
p53AIP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000120471.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29984 TP53AIP1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
605426 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9HCN2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
63970

Open Targets

More...
OpenTargetsi
ENSG00000120471

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA164726680

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TP53AIP1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003008131 – 124p53-regulated apoptosis-inducing protein 1Add BLAST124

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9HCN2

PRoteomics IDEntifications database

More...
PRIDEi
Q9HCN2

ProteomicsDB human proteome resource

More...
ProteomicsDBi
81770
81771 [Q9HCN2-2]
81772 [Q9HCN2-3]
81773 [Q9HCN2-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9HCN2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9HCN2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Only found to be expressed in thymus.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By p53/TP53.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000120471 Expressed in 111 organ(s), highest expression level in vagina

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9HCN2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA044300
HPA048797

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122018, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000432743

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9HCN2

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9HCN2

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410KC77 Eukaryota
ENOG4110P9G LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000000643

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000154669

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9HCN2

KEGG Orthology (KO)

More...
KOi
K13773

Identification of Orthologs from Complete Genome Data

More...
OMAi
VWCLTGL

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0W1P

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9HCN2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029284 TP53AIP1

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15338 TPIP1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q9HCN2-1) [UniParc]FASTAAdd to basket
Also known as: Alpha

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGSSSEASFR SAQASCSGAR RQGLGRGDQN LSVMPPNGRA QTHTPGWVSD
60 70 80 90 100
PLVLGAQVHG GCRGIEALSV SSGSWSSATV WILTGLGLGL SRPFLPGATV
110 120
LRDRPLGSAF ELSYDQKKAP LRLQ
Length:124
Mass (Da):12,935
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBE3858F03F4036C5
GO
Isoform 2 (identifier: Q9HCN2-2) [UniParc]FASTAAdd to basket
Also known as: Beta

The sequence of this isoform differs from the canonical sequence as follows:
     85-86: GL → VQ
     87-124: Missing.

Show »
Length:86
Mass (Da):8,841
Checksum:i3C53054B32433276
GO
Isoform 3 (identifier: Q9HCN2-3) [UniParc]FASTAAdd to basket
Also known as: Gamma

The sequence of this isoform differs from the canonical sequence as follows:
     50-124: DPLVLGAQVH...DQKKAPLRLQ → PCSENRDGLL...QFRALDRAGN

Note: Dubious isoform. Could be a cloning artifact.
Show »
Length:108
Mass (Da):11,288
Checksum:iAC665F271598351C
GO
Isoform 4 (identifier: Q9HCN2-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     86-89: Missing.

Show »
Length:120
Mass (Da):12,594
Checksum:iF6B84A682DAF1BFD
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0597357A → V1 PublicationCorresponds to variant dbSNP:rs35942033Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_02786550 – 124DPLVL…PLRLQ → PCSENRDGLLPATAPGRLCS HRGADIPSFQTHQDPVTASG SSELHADCPQFRALDRAGN in isoform 3. 2 PublicationsAdd BLAST75
Alternative sequenceiVSP_02786685 – 86GL → VQ in isoform 2. 1 Publication2
Alternative sequenceiVSP_02786886 – 89Missing in isoform 4. 1 Publication4
Alternative sequenceiVSP_02786787 – 124Missing in isoform 2. 1 PublicationAdd BLAST38

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB045830 mRNA Translation: BAB16421.1
AB045831 mRNA Translation: BAB16422.1
AB045832 mRNA Translation: BAB16423.1
AY302135 mRNA Translation: AAP57627.1
AP000920 Genomic DNA No translation available.
BC069399 mRNA Translation: AAH69399.1
BC069426 mRNA Translation: AAH69426.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS55797.1 [Q9HCN2-2]
CCDS55798.1 [Q9HCN2-4]
CCDS58195.1 [Q9HCN2-3]
CCDS8480.2 [Q9HCN2-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001182123.1, NM_001195194.1 [Q9HCN2-4]
NP_001182124.1, NM_001195195.1 [Q9HCN2-2]
NP_001238893.1, NM_001251964.1 [Q9HCN2-3]
NP_071395.2, NM_022112.2 [Q9HCN2-1]
XP_016873605.1, XM_017018116.1 [Q9HCN2-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.160953

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000458238; ENSP00000390694; ENSG00000120471 [Q9HCN2-2]
ENST00000527504; ENSP00000435175; ENSG00000120471 [Q9HCN2-3]
ENST00000530777; ENSP00000432908; ENSG00000120471 [Q9HCN2-4]
ENST00000531399; ENSP00000432743; ENSG00000120471 [Q9HCN2-1]
ENST00000602346; ENSP00000473353; ENSG00000120471 [Q9HCN2-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
63970

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:63970

UCSC genome browser

More...
UCSCi
uc001qex.5 human [Q9HCN2-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB045830 mRNA Translation: BAB16421.1
AB045831 mRNA Translation: BAB16422.1
AB045832 mRNA Translation: BAB16423.1
AY302135 mRNA Translation: AAP57627.1
AP000920 Genomic DNA No translation available.
BC069399 mRNA Translation: AAH69399.1
BC069426 mRNA Translation: AAH69426.1
CCDSiCCDS55797.1 [Q9HCN2-2]
CCDS55798.1 [Q9HCN2-4]
CCDS58195.1 [Q9HCN2-3]
CCDS8480.2 [Q9HCN2-1]
RefSeqiNP_001182123.1, NM_001195194.1 [Q9HCN2-4]
NP_001182124.1, NM_001195195.1 [Q9HCN2-2]
NP_001238893.1, NM_001251964.1 [Q9HCN2-3]
NP_071395.2, NM_022112.2 [Q9HCN2-1]
XP_016873605.1, XM_017018116.1 [Q9HCN2-1]
UniGeneiHs.160953

3D structure databases

ProteinModelPortaliQ9HCN2
SMRiQ9HCN2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122018, 2 interactors
STRINGi9606.ENSP00000432743

PTM databases

iPTMnetiQ9HCN2
PhosphoSitePlusiQ9HCN2

Polymorphism and mutation databases

BioMutaiTP53AIP1

Proteomic databases

PaxDbiQ9HCN2
PRIDEiQ9HCN2
ProteomicsDBi81770
81771 [Q9HCN2-2]
81772 [Q9HCN2-3]
81773 [Q9HCN2-4]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
63970
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000458238; ENSP00000390694; ENSG00000120471 [Q9HCN2-2]
ENST00000527504; ENSP00000435175; ENSG00000120471 [Q9HCN2-3]
ENST00000530777; ENSP00000432908; ENSG00000120471 [Q9HCN2-4]
ENST00000531399; ENSP00000432743; ENSG00000120471 [Q9HCN2-1]
ENST00000602346; ENSP00000473353; ENSG00000120471 [Q9HCN2-3]
GeneIDi63970
KEGGihsa:63970
UCSCiuc001qex.5 human [Q9HCN2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
63970
DisGeNETi63970
EuPathDBiHostDB:ENSG00000120471.14

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TP53AIP1
HGNCiHGNC:29984 TP53AIP1
HPAiHPA044300
HPA048797
MIMi605426 gene
neXtProtiNX_Q9HCN2
OpenTargetsiENSG00000120471
PharmGKBiPA164726680

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410KC77 Eukaryota
ENOG4110P9G LUCA
GeneTreeiENSGT00390000000643
HOGENOMiHOG000154669
InParanoidiQ9HCN2
KOiK13773
OMAiVWCLTGL
OrthoDBiEOG091G0W1P
PhylomeDBiQ9HCN2

Enzyme and pathway databases

ReactomeiR-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
P53AIP1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
63970

Protein Ontology

More...
PROi
PR:Q9HCN2

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000120471 Expressed in 111 organ(s), highest expression level in vagina
GenevisibleiQ9HCN2 HS

Family and domain databases

InterProiView protein in InterPro
IPR029284 TP53AIP1
PfamiView protein in Pfam
PF15338 TPIP1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTPIP1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9HCN2
Secondary accession number(s): Q6NT40
, Q7Z6F7, Q9HCN0, Q9HCN1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2001
Last modified: November 7, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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