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Entry version 116 (16 Oct 2019)
Sequence version 2 (05 May 2009)
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Protein

Zinc finger SWIM domain-containing protein 6

Gene

ZSWIM6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

involved in nervous system development, important for striatal morphology and motor regulation.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri246 – 283SWIM-typePROSITE-ProRule annotationAdd BLAST38

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processNeurogenesis
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger SWIM domain-containing protein 6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZSWIM61 PublicationImported
Synonyms:KIAA1577
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29316 ZSWIM6

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
615951 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9HCJ5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Acromelic frontonasal dysostosis (AFND)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA rare variant form of frontonasal dysplasia, an array of abnormalities affecting the eyes, forehead and nose and linked to midfacial dysraphia. The clinical picture is highly variable. Major findings include true ocular hypertelorism, broadening of the nasal root, median facial cleft affecting the nose and/or upper lip and palate, unilateral or bilateral clefting of the alae nasi, lack of formation of the nasal tip, anterior cranium bifidum occultum, a V-shaped or widow's peak frontal hairline. AFND is characterized by the association of frontonasal malformations with various combinations of polydactyly, tibial hypoplasia, epibulbar dermoid, encephalocoele, corpus callosum agenesis and Dandy-Walker malformation.
Related information in OMIM
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0718021163R → W in AFND. 1 PublicationCorresponds to variant dbSNP:rs587777695EnsemblClinVar.1
Neurodevelopmental disorder with movement abnormalities, abnormal gait, and autistic features (NEDMAGA)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionAn autosomal dominant neurodevelopmental disorder characterized by infantile-onset global developmental delay, severe to profound intellectual disability, mildly delayed walking with broad-based and unsteady gait, and absence of meaningful language. Patients have features of autism, with repetitive behaviors and poor communication, but usually are socially reactive and have a happy demeanor. More variable neurologic features include mild seizures, spasticity, and peripheral neuropathy.
Related information in OMIM
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_080756913 – 1215Missing in NEDMAGA. 1 PublicationAdd BLAST303

Keywords - Diseasei

Disease mutation, Dwarfism, Mental retardation

Organism-specific databases

DisGeNET

More...
DisGeNETi
57688

MalaCards human disease database

More...
MalaCardsi
ZSWIM6
MIMi603671 phenotype
617865 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000130449

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
1827 Acromelic frontonasal dysplasia

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134910181

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9HCJ5

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZSWIM6

Domain mapping of disease mutations (DMDM)

More...
DMDMi
229462808

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002231051 – 1215Zinc finger SWIM domain-containing protein 6Add BLAST1215

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9HCJ5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9HCJ5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9HCJ5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9HCJ5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9HCJ5

PeptideAtlas

More...
PeptideAtlasi
Q9HCJ5

PRoteomics IDEntifications database

More...
PRIDEi
Q9HCJ5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
81740

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9HCJ5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9HCJ5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000130449 Expressed in 204 organ(s), highest expression level in forebrain

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9HCJ5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA035938

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
121714, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q9HCJ5, 5 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000252744

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi19 – 154Gly-richAdd BLAST136
Compositional biasi155 – 158Poly-Ser4
Compositional biasi160 – 197Ala-richAdd BLAST38

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri246 – 283SWIM-typePROSITE-ProRule annotationAdd BLAST38

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3615 Eukaryota
ENOG410XPZG LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155496

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231419

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9HCJ5

Identification of Orthologs from Complete Genome Data

More...
OMAi
KKWNGVD

Database of Orthologous Groups

More...
OrthoDBi
1585262at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9HCJ5

TreeFam database of animal gene trees

More...
TreeFami
TF324881

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007527 Znf_SWIM

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50966 ZF_SWIM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9HCJ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAERGQQPPP AKRLCCRPGG GGGGGGSSGG GGGAGGGYSS ACRPGPRAGG
60 70 80 90 100
AAAAAACGGG AALGLLPPGK TQSPESLLDI AARRVAEKWP FQRVEERFER
110 120 130 140 150
IPEPVQRRIV YWSFPRSERE ICMYSSFNTG GGAAGGPGDD SGGGGGAGGG
160 170 180 190 200
GGGGSSSSPA ATSAAATSAA AAAAAAAAAA AAAAGAGAPS VGAAGAADGG
210 220 230 240 250
DETRLPFRRG IALLESGCVD NVLQVGFHLS GTVTEPAIQS EPETVCNVAI
260 270 280 290 300
SFDRCKITSV TCSCGNKDIF YCAHVVALSL YRIRKPDQVK LHLPISETLF
310 320 330 340 350
QMNRDQLQKF VQYLITVHHT EVLPTAQKLA DEILSQNSEI NQVHGAPDPT
360 370 380 390 400
AGASIDDENC WHLDEEQVQE QVKLFLSQGG YHGSGKQLNL LFAKVREMLK
410 420 430 440 450
MRDSNGARML TLITEQFMAD PRLSLWRQQG TAMTDKYRQL WDELGALWMC
460 470 480 490 500
IVLNPHCKLE QKASWLKQLK KWNSVDVCPW EDGNHGSELP NLTNALPQGA
510 520 530 540 550
NANQDSSNRP HRTVFTRAIE ACDLHWQDSH LQHIISSDLY TNYCYHDDTE
560 570 580 590 600
NSLFDSRGWP LWHEHVPTAC ARVDALRSHG YPREALRLAI AIVNTLRRQQ
610 620 630 640 650
QKQLEMFRTQ KKELPHKNIT SITNLEGWVG HPLDPVGTLF SSLMEACRID
660 670 680 690 700
DENLSGFSDF TENMGQCKSL EYQHLPAHKF LEEGESYLTL AVEVALIGLG
710 720 730 740 750
QQRIMPDGLY TQEKVCRNEE QLISKLQEIE LDDTLVKIFR KQAVFLLEAG
760 770 780 790 800
PYSGLGEIIH RESVPMHTFA KYLFTSLLPH DAELAYKIAL RAMRLLVLES
810 820 830 840 850
TAPSGDLTRP HHIASVVPNR YPRWFTLSHI ESQQCELAST MLTAAKGDVR
860 870 880 890 900
RLETVLESIQ KNIHSSSHIF KLAQDAFKIA TLMDSLPDIT LLKVSLELGL
910 920 930 940 950
QVMRMTLSTL NWRRREMVRW LVTCATEVGV YALDSIMQTW FTLFTPTEAT
960 970 980 990 1000
SIVATTVMSN STIVRLHLDC HQQEKLASSA RTLALQCAMK DPQNCALSAL
1010 1020 1030 1040 1050
TLCEKDHIAF ETAYQIVLDA ATTGMSYTQL FTIARYMEHR GYPMRAYKLA
1060 1070 1080 1090 1100
TLAMTHLNLS YNQDTHPAIN DVLWACALSH SLGKNELAAI IPLVVKSVKC
1110 1120 1130 1140 1150
ATVLSDILRR CTLTTPGMVG LHGRRNSGKL MSLDKAPLRQ LLDATIGAYI
1160 1170 1180 1190 1200
NTTHSRLTHI SPRHYSEFIE FLSKARETFL MAHDGHIQFT QFIDNLKQIY
1210
KGKKKLMMLV RERFG
Length:1,215
Mass (Da):133,470
Last modified:May 5, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i828B5AA0644EECE0
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_076431763S → R1 Publication1
Natural variantiVAR_080756913 – 1215Missing in NEDMAGA. 1 PublicationAdd BLAST303
Natural variantiVAR_0718021163R → W in AFND. 1 PublicationCorresponds to variant dbSNP:rs587777695EnsemblClinVar.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC122718 Genomic DNA No translation available.
AC008836 Genomic DNA No translation available.
AB046797 mRNA Translation: BAB13403.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47215.1

NCBI Reference Sequences

More...
RefSeqi
NP_065979.1, NM_020928.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000252744; ENSP00000252744; ENSG00000130449

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57688

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:57688

UCSC genome browser

More...
UCSCi
uc003jsr.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC122718 Genomic DNA No translation available.
AC008836 Genomic DNA No translation available.
AB046797 mRNA Translation: BAB13403.1
CCDSiCCDS47215.1
RefSeqiNP_065979.1, NM_020928.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi121714, 4 interactors
IntActiQ9HCJ5, 5 interactors
STRINGi9606.ENSP00000252744

PTM databases

iPTMnetiQ9HCJ5
PhosphoSitePlusiQ9HCJ5

Polymorphism and mutation databases

BioMutaiZSWIM6
DMDMi229462808

Proteomic databases

EPDiQ9HCJ5
jPOSTiQ9HCJ5
MassIVEiQ9HCJ5
MaxQBiQ9HCJ5
PaxDbiQ9HCJ5
PeptideAtlasiQ9HCJ5
PRIDEiQ9HCJ5
ProteomicsDBi81740

Genome annotation databases

EnsembliENST00000252744; ENSP00000252744; ENSG00000130449
GeneIDi57688
KEGGihsa:57688
UCSCiuc003jsr.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57688
DisGeNETi57688

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZSWIM6
HGNCiHGNC:29316 ZSWIM6
HPAiHPA035938
MalaCardsiZSWIM6
MIMi603671 phenotype
615951 gene
617865 phenotype
neXtProtiNX_Q9HCJ5
OpenTargetsiENSG00000130449
Orphaneti1827 Acromelic frontonasal dysplasia
PharmGKBiPA134910181

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3615 Eukaryota
ENOG410XPZG LUCA
GeneTreeiENSGT00940000155496
HOGENOMiHOG000231419
InParanoidiQ9HCJ5
OMAiKKWNGVD
OrthoDBi1585262at2759
PhylomeDBiQ9HCJ5
TreeFamiTF324881

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZSWIM6 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
57688
PharosiQ9HCJ5

Protein Ontology

More...
PROi
PR:Q9HCJ5

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000130449 Expressed in 204 organ(s), highest expression level in forebrain
GenevisibleiQ9HCJ5 HS

Family and domain databases

InterProiView protein in InterPro
IPR007527 Znf_SWIM
PROSITEiView protein in PROSITE
PS50966 ZF_SWIM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZSWM6_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9HCJ5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: May 5, 2009
Last modified: October 16, 2019
This is version 116 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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