UniProtKB - Q9HC77 (CENPJ_HUMAN)
Centromere protein J
CENPJ
Functioni
GO - Molecular functioni
- gamma-tubulin binding Source: MGI
- identical protein binding Source: IntAct
- protein domain specific binding Source: UniProtKB
- protein kinase binding Source: UniProtKB
- transcription coactivator activity Source: MGI
- tubulin binding Source: UniProtKB
GO - Biological processi
- astral microtubule nucleation Source: MGI
- cell division Source: UniProtKB
- centriole elongation Source: UniProtKB
- centriole replication Source: UniProtKB
- ciliary basal body-plasma membrane docking Source: Reactome
- cilium assembly Source: GO_Central
- G2/M transition of mitotic cell cycle Source: Reactome
- microtubule nucleation Source: UniProtKB
- microtubule polymerization Source: UniProtKB
- positive regulation of centriole elongation Source: UniProtKB
- positive regulation of establishment of protein localization Source: UniProtKB
- positive regulation of receptor signaling pathway via JAK-STAT Source: MGI
- regulation of centriole replication Source: UniProtKB
- regulation of G2/M transition of mitotic cell cycle Source: Reactome
Enzyme and pathway databases
PathwayCommonsi | Q9HC77 |
Reactomei | R-HSA-2565942, Regulation of PLK1 Activity at G2/M Transition R-HSA-380259, Loss of Nlp from mitotic centrosomes R-HSA-380270, Recruitment of mitotic centrosome proteins and complexes R-HSA-380284, Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380320, Recruitment of NuMA to mitotic centrosomes R-HSA-5620912, Anchoring of the basal body to the plasma membrane R-HSA-6804115, TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-8854518, AURKA Activation by TPX2 |
SIGNORi | Q9HC77 |
Names & Taxonomyi
Protein namesi | Recommended name: Centromere protein JShort name: CENP-J Alternative name(s): Centrosomal P4.1-associated protein LAG-3-associated protein LYST-interacting protein 1 |
Gene namesi | Name:CENPJ Synonyms:CPAP, LAP, LIP1 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:17272, CENPJ |
MIMi | 609279, gene |
neXtProti | NX_Q9HC77 |
VEuPathDBi | HostDB:ENSG00000151849.14 |
Subcellular locationi
Cytoskeleton
- centrosome 3 Publications
- centriole 3 Publications
Note: Localized within the center of microtubule asters (PubMed:11003675). During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles (PubMed:17681131).2 Publications
Cytoskeleton
- centriole Source: UniProtKB
- centrosome Source: UniProtKB
- gamma-tubulin small complex Source: UniProtKB
- microtubule Source: UniProtKB-KW
Cytosol
- cytosol Source: Reactome
Nucleus
- nucleoplasm Source: HPA
- nucleus Source: GO_Central
Plasma Membrane
- plasma membrane Source: HPA
Other locations
- cytoplasm Source: MGI
Keywords - Cellular componenti
Cytoplasm, Cytoskeleton, MicrotubulePathology & Biotechi
Involvement in diseasei
Microcephaly 6, primary, autosomal recessive (MCPH6)2 Publications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_032433 | 1235 | E → V in MCPH6; reduced interaction with STIL. 2 PublicationsCorresponds to variant dbSNP:rs121434311EnsemblClinVar. | 1 |
Seckel syndrome 4 (SCKL4)1 Publication
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 338 | F → A: Decreases interaction with alpha/beta-tubulin; when associated with A-339 and A-341. 1 Publication | 1 | |
Mutagenesisi | 339 | E → A: Decreases interaction with alpha/beta-tubulin; when associated with A-338 and A-341. 1 Publication | 1 | |
Mutagenesisi | 341 | Y → A: Decreases interaction with alpha/beta-tubulin; when associated with A-338 and A-339. 1 Publication | 1 | |
Mutagenesisi | 343 | E → A: Slightly decreases interaction with alpha/beta-tubulin; causes overly long daughter centrioles and enhances ciliary length; when associated with A-344. 1 Publication | 1 | |
Mutagenesisi | 344 | E → A: Slightly decreases interaction with alpha/beta-tubulin; causes overly long daughter centrioles and enhances ciliary length; when associated with A-343. 1 Publication | 1 | |
Mutagenesisi | 375 | F → A: Decreases interaction with alpha/beta-tubulin; disrupts association with microtubule distal tip; no effect on association with microtubule lattice; when associated with A-385. 1 Publication | 1 | |
Mutagenesisi | 375 | F → A: Strongly decreases interaction with alpha/beta-tubulin; causes shorter centrioles and doublet microtubules in cilia. 1 Publication | 1 | |
Mutagenesisi | 377 | K → E: Decreases interaction with alpha/beta-tubulin; disrupts association with microtubule distal tip; no effect on association with microtubule lattice; when associated with E-378. 1 Publication | 1 | |
Mutagenesisi | 378 | R → E: Decreases interaction with alpha/beta-tubulin; disrupts association with microtubule distal tip; no effect on association with microtubule lattice; when associated with E-377. 1 Publication | 1 | |
Mutagenesisi | 385 | F → A: Decreases interaction with alpha/beta-tubulin; disrupts association with microtubule distal tip; no effect on association with microtubule lattice; when associated with A-375. 1 Publication | 1 | |
Mutagenesisi | 589 | S → A: Abolishes phosphorylation by PLK2 and procentriole formation; when associated with A-595. 1 Publication | 1 | |
Mutagenesisi | 595 | S → A: Abolishes phosphorylation by PLK2 and procentriole formation; when associated with A-589. 1 Publication | 1 |
Keywords - Diseasei
Disease variant, Dwarfism, Mental retardation, Primary microcephalyOrganism-specific databases
DisGeNETi | 55835 |
MalaCardsi | CENPJ |
MIMi | 608393, phenotype 613676, phenotype |
OpenTargetsi | ENSG00000151849 |
Orphaneti | 2512, Autosomal recessive primary microcephaly 808, Seckel syndrome |
PharmGKBi | PA26403 |
Miscellaneous databases
Pharosi | Q9HC77, Tbio |
Genetic variation databases
BioMutai | CENPJ |
DMDMi | 62899891 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000089480 | 1 – 1338 | Centromere protein JAdd BLAST | 1338 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 260 | PhosphoserineCombined sources | 1 | |
Modified residuei | 316 | PhosphoserineCombined sources | 1 | |
Modified residuei | 540 | PhosphoserineCombined sources | 1 | |
Modified residuei | 589 | Phosphoserine; by PLK21 Publication | 1 | |
Modified residuei | 595 | Phosphoserine; by PLK2 and PLK41 Publication | 1 | |
Modified residuei | 759 | PhosphoserineCombined sources | 1 |
Post-translational modificationi
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q9HC77 |
jPOSTi | Q9HC77 |
MassIVEi | Q9HC77 |
MaxQBi | Q9HC77 |
PaxDbi | Q9HC77 |
PeptideAtlasi | Q9HC77 |
PRIDEi | Q9HC77 |
ProteomicsDBi | 63008 81646 [Q9HC77-1] |
PTM databases
iPTMneti | Q9HC77 |
PhosphoSitePlusi | Q9HC77 |
Expressioni
Gene expression databases
Bgeei | ENSG00000151849, Expressed in left lobe of thyroid gland and 205 other tissues |
ExpressionAtlasi | Q9HC77, baseline and differential |
Genevisiblei | Q9HC77, HS |
Organism-specific databases
HPAi | ENSG00000151849, Low tissue specificity |
Interactioni
Subunit structurei
Forms homodimers (PubMed:27219064). Associates with microtubules plus ends; binds to beta-tublin subunits exposed on microtubule outer surface at its distal tip; also associates with microtubule lattice (PubMed:19131341, PubMed:27219064, PubMed:27306797). Associated with the gamma-tubulin complex.
Interacts with the head domain of EPB41 (PubMed:11003675).
Interacts with LYST (PubMed:11984006).
Interacts with CEP152 (via C-terminus) (PubMed:20852615).
Interacts with STIL (PubMed:22020124, PubMed:25385835).
Forms a complex with STIL and SASS6 (PubMed:22020124).
7 PublicationsBinary interactionsi
Hide detailsQ9HC77
GO - Molecular functioni
- gamma-tubulin binding Source: MGI
- identical protein binding Source: IntAct
- protein domain specific binding Source: UniProtKB
- protein kinase binding Source: UniProtKB
- tubulin binding Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 120939, 156 interactors |
ComplexPortali | CPX-1159, CPAP-STIL complex |
DIPi | DIP-49904N |
IntActi | Q9HC77, 137 interactors |
MINTi | Q9HC77 |
STRINGi | 9606.ENSP00000371308 |
Miscellaneous databases
RNActi | Q9HC77, protein |
Structurei
Secondary structure
3D structure databases
BMRBi | Q9HC77 |
SMRi | Q9HC77 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 319 – 394 | Alpha/beta-tubulin binding1 PublicationAdd BLAST | 76 | |
Regioni | 895 – 1338 | Interaction with STIL2 PublicationsAdd BLAST | 444 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | ENOG502QQR0, Eukaryota |
GeneTreei | ENSGT00530000063927 |
HOGENOMi | CLU_008072_0_0_1 |
InParanoidi | Q9HC77 |
OMAi | EPLNFPD |
OrthoDBi | 1249457at2759 |
PhylomeDBi | Q9HC77 |
TreeFami | TF343156 |
Family and domain databases
InterProi | View protein in InterPro IPR033068, CENP-J IPR009852, Tcp10_C_dom IPR026581, TCP10_fam |
PANTHERi | PTHR10331, PTHR10331, 1 hit PTHR10331:SF23, PTHR10331:SF23, 1 hit |
Pfami | View protein in Pfam PF07202, Tcp10_C, 4 hits |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MFLMPTSSEL NSGQNFLTQW MTNPSRAGVI LNRGFPILEA DKEKRAAVDI
60 70 80 90 100
STSFPIKGTH FSDSFSFINE EDSLLEEQKL ESNNPYKPQS DKSETHTAFP
110 120 130 140 150
CIKKGPQVAA CHSAPGHQEE NKNDFIPDLA SEFKEGAYKD PLFKKLEQLK
160 170 180 190 200
EVQQKKQEQL KRQQLEQLQR LMEEQEKLLT MVSGQCTLPG LSLLPDDQSQ
210 220 230 240 250
KHRSPGNTTT GERATCCFPS YVYPDPTQEE TYPSNILSHE QSNFCRTAHG
260 270 280 290 300
DFVLTSKRAS PNLFSEAQYQ EAPVEKNNLK EENRNHPTGE SILCWEKVTE
310 320 330 340 350
QIQEANDKNL QKHDDSSEVA NIEERPIKAA IGERKQTFED YLEEQIQLEE
360 370 380 390 400
QELKQKQLKE AEGPLPIKAK PKQPFLKRGE GLARFTNAKS KFQKGKESKL
410 420 430 440 450
VTNQSTSEDQ PLFKMDRQQL QRKTALKNKE LCADNPILKK DSKARTKSGS
460 470 480 490 500
VTLSQKPKML KCSNRKSLSP SGLKIQTGKK CDGQFRDQIK FENKVTSNNK
510 520 530 540 550
ENVTECPKPC DTGCTGWNKT QGKDRLPLST GPASRLAAKS PIRETMKESE
560 570 580 590 600
SSLDVSLQKK LETWEREKEK ENLELDEFLF LEQAADEISF SSNSSFVLKI
610 620 630 640 650
LERDQQICKG HRMSSTPVKA VPQKTNPADP ISHCNRSEDL DHTAREKESE
660 670 680 690 700
CEVAPKQLHS LSSADELREQ PCKIRKAVQK STSENQTEWN ARDDEGVPNS
710 720 730 740 750
DSSTDSEEQL DVTIKPSTED RERGISSRED SPQVCDDKGP FKDTRTQEDK
760 770 780 790 800
RRDVDLDLSD KDYSSDESIM ESIKHKVSEP SRSSSLSLSK MDFDDERTWT
810 820 830 840 850
DLEENLCNHD VVLGNESTYG TPQTCYPNNE IGILDKTIKR KIAPVKRGED
860 870 880 890 900
LSKSRRSRSP PTSELMMKFF PSLKPKPKSD SHLGNELKLN ISQDQPPGDN
910 920 930 940 950
ARSQVLREKI IELETEIEKF KAENASLAKL RIERESALEK LRKEIADFEQ
960 970 980 990 1000
QKAKELARIE EFKKEEMRKL QKERKVFEKY TTAARTFPDK KEREEIQTLK
1010 1020 1030 1040 1050
QQIADLREDL KRKETKWSST HSRLRSQIQM LVRENTDLRE EIKVMERFRL
1060 1070 1080 1090 1100
DAWKRAEAIE SSLEVEKKDK LANTSVRFQN SQISSGTQVE KYKKNYLPMQ
1110 1120 1130 1140 1150
GNPPRRSKSA PPRDLGNLDK GQAASPREPL EPLNFPDPEY KEEEEDQDIQ
1160 1170 1180 1190 1200
GEISHPDGKV EKVYKNGCRV ILFPNGTRKE VSADGKTITV TFFNGDVKQV
1210 1220 1230 1240 1250
MPDQRVIYYY AAAQTTHTTY PEGLEVLHFS SGQIEKHYPD GRKEITFPDQ
1260 1270 1280 1290 1300
TVKNLFPDGQ EESIFPDGTI VRVQRDGNKL IEFNNGQREL HTAQFKRREY
1310 1320 1330
PDGTVKTVYA NGHQETKYRS GRIRVKDKEG NVLMDTEL
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF6VUX8 | F6VUX8_HUMAN | Centromere protein J | CENPJ | 1,136 | Annotation score: | ||
H0Y5L8 | H0Y5L8_HUMAN | Centromere protein J | CENPJ | 196 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 129 | L → R in AAG21074 (PubMed:11003675).Curated | 1 | |
Sequence conflicti | 1142 | E → R in AAG49440 (PubMed:11984006).Curated | 1 | |
Sequence conflicti | 1224 | L → W in AAG49440 (PubMed:11984006).Curated | 1 | |
Sequence conflicti | 1333 | L → S in AAG21074 (PubMed:11003675).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_032427 | 21 | M → V. Corresponds to variant dbSNP:rs35498994EnsemblClinVar. | 1 | |
Natural variantiVAR_032428 | 55 | P → A. Corresponds to variant dbSNP:rs17081389EnsemblClinVar. | 1 | |
Natural variantiVAR_032429 | 63 | D → H. Corresponds to variant dbSNP:rs7336216EnsemblClinVar. | 1 | |
Natural variantiVAR_032430 | 85 | P → T. Corresponds to variant dbSNP:rs9511510EnsemblClinVar. | 1 | |
Natural variantiVAR_032431 | 151 | E → G. Corresponds to variant dbSNP:rs34177811EnsemblClinVar. | 1 | |
Natural variantiVAR_032432 | 879 | S → A. Corresponds to variant dbSNP:rs17402892EnsemblClinVar. | 1 | |
Natural variantiVAR_032433 | 1235 | E → V in MCPH6; reduced interaction with STIL. 2 PublicationsCorresponds to variant dbSNP:rs121434311EnsemblClinVar. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_056831 | 1073 – 1086 | NTSVR…QISSG → AIHLEDPSLHLLVI in isoform 2. 1 PublicationAdd BLAST | 14 | |
Alternative sequenceiVSP_056832 | 1087 – 1338 | Missing in isoform 2. 1 PublicationAdd BLAST | 252 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF139625 mRNA Translation: AAG21074.1 AL833182 mRNA Translation: CAI46195.1 AL354798 Genomic DNA No translation available. CH471075 Genomic DNA Translation: EAX08354.1 BC024209 mRNA Translation: AAH24209.3 Different initiation. BC113110 mRNA Translation: AAI13111.1 BC113662 mRNA Translation: AAI13663.1 BC113664 mRNA Translation: AAI13665.1 AJ303006 mRNA Translation: CAC80028.1 AF141337 mRNA Translation: AAG49440.1 |
CCDSi | CCDS9310.1 [Q9HC77-1] |
RefSeqi | NP_060921.3, NM_018451.4 [Q9HC77-1] |
Genome annotation databases
Ensembli | ENST00000381884; ENSP00000371308; ENSG00000151849 [Q9HC77-1] ENST00000616936; ENSP00000477511; ENSG00000151849 [Q9HC77-2] |
GeneIDi | 55835 |
KEGGi | hsa:55835 |
UCSCi | uc001upt.6, human [Q9HC77-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF139625 mRNA Translation: AAG21074.1 AL833182 mRNA Translation: CAI46195.1 AL354798 Genomic DNA No translation available. CH471075 Genomic DNA Translation: EAX08354.1 BC024209 mRNA Translation: AAH24209.3 Different initiation. BC113110 mRNA Translation: AAI13111.1 BC113662 mRNA Translation: AAI13663.1 BC113664 mRNA Translation: AAI13665.1 AJ303006 mRNA Translation: CAC80028.1 AF141337 mRNA Translation: AAG49440.1 |
CCDSi | CCDS9310.1 [Q9HC77-1] |
RefSeqi | NP_060921.3, NM_018451.4 [Q9HC77-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5EIB | X-ray | 2.10 | F | 372-394 | [»] | |
5ITZ | X-ray | 2.20 | D | 311-422 | [»] | |
BMRBi | Q9HC77 | |||||
SMRi | Q9HC77 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 120939, 156 interactors |
ComplexPortali | CPX-1159, CPAP-STIL complex |
DIPi | DIP-49904N |
IntActi | Q9HC77, 137 interactors |
MINTi | Q9HC77 |
STRINGi | 9606.ENSP00000371308 |
PTM databases
iPTMneti | Q9HC77 |
PhosphoSitePlusi | Q9HC77 |
Genetic variation databases
BioMutai | CENPJ |
DMDMi | 62899891 |
Proteomic databases
EPDi | Q9HC77 |
jPOSTi | Q9HC77 |
MassIVEi | Q9HC77 |
MaxQBi | Q9HC77 |
PaxDbi | Q9HC77 |
PeptideAtlasi | Q9HC77 |
PRIDEi | Q9HC77 |
ProteomicsDBi | 63008 81646 [Q9HC77-1] |
Protocols and materials databases
Antibodypediai | 22520, 183 antibodies |
Genome annotation databases
Ensembli | ENST00000381884; ENSP00000371308; ENSG00000151849 [Q9HC77-1] ENST00000616936; ENSP00000477511; ENSG00000151849 [Q9HC77-2] |
GeneIDi | 55835 |
KEGGi | hsa:55835 |
UCSCi | uc001upt.6, human [Q9HC77-1] |
Organism-specific databases
CTDi | 55835 |
DisGeNETi | 55835 |
GeneCardsi | CENPJ |
HGNCi | HGNC:17272, CENPJ |
HPAi | ENSG00000151849, Low tissue specificity |
MalaCardsi | CENPJ |
MIMi | 608393, phenotype 609279, gene 613676, phenotype |
neXtProti | NX_Q9HC77 |
OpenTargetsi | ENSG00000151849 |
Orphaneti | 2512, Autosomal recessive primary microcephaly 808, Seckel syndrome |
PharmGKBi | PA26403 |
VEuPathDBi | HostDB:ENSG00000151849.14 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QQR0, Eukaryota |
GeneTreei | ENSGT00530000063927 |
HOGENOMi | CLU_008072_0_0_1 |
InParanoidi | Q9HC77 |
OMAi | EPLNFPD |
OrthoDBi | 1249457at2759 |
PhylomeDBi | Q9HC77 |
TreeFami | TF343156 |
Enzyme and pathway databases
PathwayCommonsi | Q9HC77 |
Reactomei | R-HSA-2565942, Regulation of PLK1 Activity at G2/M Transition R-HSA-380259, Loss of Nlp from mitotic centrosomes R-HSA-380270, Recruitment of mitotic centrosome proteins and complexes R-HSA-380284, Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380320, Recruitment of NuMA to mitotic centrosomes R-HSA-5620912, Anchoring of the basal body to the plasma membrane R-HSA-6804115, TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-8854518, AURKA Activation by TPX2 |
SIGNORi | Q9HC77 |
Miscellaneous databases
BioGRID-ORCSi | 55835, 114 hits in 996 CRISPR screens |
ChiTaRSi | CENPJ, human |
GeneWikii | CENPJ |
GenomeRNAii | 55835 |
Pharosi | Q9HC77, Tbio |
PROi | PR:Q9HC77 |
RNActi | Q9HC77, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000151849, Expressed in left lobe of thyroid gland and 205 other tissues |
ExpressionAtlasi | Q9HC77, baseline and differential |
Genevisiblei | Q9HC77, HS |
Family and domain databases
InterProi | View protein in InterPro IPR033068, CENP-J IPR009852, Tcp10_C_dom IPR026581, TCP10_fam |
PANTHERi | PTHR10331, PTHR10331, 1 hit PTHR10331:SF23, PTHR10331:SF23, 1 hit |
Pfami | View protein in Pfam PF07202, Tcp10_C, 4 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CENPJ_HUMAN | |
Accessioni | Q9HC77Primary (citable) accession number: Q9HC77 Secondary accession number(s): Q2KHM6 Q9C067 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 26, 2005 |
Last sequence update: | April 26, 2005 | |
Last modified: | April 7, 2021 | |
This is version 163 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 13
Human chromosome 13: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families