Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 170 (02 Jun 2021)
Sequence version 2 (11 Dec 2019)
Previous versions | rss
Add a publicationFeedback
Protein

Zinc finger protein 287

Gene

ZNF287

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri368 – 390C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri396 – 418C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri424 – 446C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri452 – 474C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri480 – 502C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri508 – 530C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri536 – 558C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri564 – 586C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri592 – 614C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri620 – 642C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri648 – 670C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri676 – 698C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri704 – 726C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri732 – 754C2H2-type 14PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9HBT7

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 287Curated
Alternative name(s):
Zinc finger protein with KRAB and SCAN domains 13
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF287Imported
Synonyms:ZKSCAN13
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13502, ZNF287

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9HBT7

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000141040.14

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
57336

Open Targets

More...
OpenTargetsi
ENSG00000141040

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37788

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9HBT7, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF287

Domain mapping of disease mutations (DMDM)

More...
DMDMi
20141038

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000475111 – 761Zinc finger protein 287Add BLAST761

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9HBT7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9HBT7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9HBT7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9HBT7

PeptideAtlas

More...
PeptideAtlasi
Q9HBT7

PRoteomics IDEntifications database

More...
PRIDEi
Q9HBT7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
81591

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9HBT7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9HBT7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000141040, Expressed in adenohypophysis and 146 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9HBT7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9HBT7, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000141040, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
121490, 11 interactors

Protein interaction database and analysis system

More...
IntActi
Q9HBT7, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000379168

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9HBT7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9HBT7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini49 – 131SCAN boxPROSITE-ProRule annotationAdd BLAST83
Domaini170 – 238KRABPROSITE-ProRule annotationAdd BLAST69

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni134 – 154DisorderedSequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri368 – 390C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri396 – 418C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri424 – 446C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri452 – 474C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri480 – 502C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri508 – 530C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri536 – 558C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri564 – 586C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri592 – 614C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri620 – 642C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri648 – 670C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri676 – 698C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri704 – 726C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri732 – 754C2H2-type 14PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162333

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_49_8_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9HBT7

Identification of Orthologs from Complete Genome Data

More...
OMAi
GFWKIHT

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9HBT7

TreeFam database of animal gene trees

More...
TreeFami
TF350843

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765, KRAB_A-box, 1 hit
cd07936, SCAN, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.4020.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR003309, SCAN_dom
IPR038269, SCAN_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352, KRAB, 1 hit
PF02023, SCAN, 1 hit
PF00096, zf-C2H2, 14 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349, KRAB, 1 hit
SM00431, SCAN, 1 hit
SM00355, ZnF_C2H2, 14 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 8 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805, KRAB, 1 hit
PS50804, SCAN_BOX, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 14 hits
PS50157, ZINC_FINGER_C2H2_2, 14 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9HBT7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLASSKRMNS SSRSQILLRW KSDKAQSGPY NVEKEILTSR FLRDTETCRQ
60 70 80 90 100
NFRNFPYPDL AGPRKALSQL RELCLKWLRP EIHSKEQILE LLVLEQFLTI
110 120 130 140 150
LPGEVRTWVK SQYPESSEEA VTLVEDLTQI LEEEAPQNST LSQDTPEEDP
160 170 180 190 200
RGKHAFQTGW LNDLVTKESM TFKDVAVDIT QEDWELMRPV QKELYKTVTL
210 220 230 240 250
QNYWNMVSLG LTVYRPTVIP ILEEPWMVIK EILEGPSPEW ETKAQACTPV
260 270 280 290 300
EDMSKLTKEE THTIKLEDSY DYDDRLERRG KGGFWKIHTD ERGFSLKSVL
310 320 330 340 350
SQEYDPTEEC LSKYDIYRNN FEKHSNLIVQ FDTQLDNKTS VYNEGRATFN
360 370 380 390 400
HVSYGIVHRK ILPGEKPYKC NVCGKKFRKY PSLLKHQSTH AKEKSYECEE
410 420 430 440 450
CGKEFRHISS LIAHQRMHTG EKPYECHQCG KAFSQRAHLT IHQRIHTGEK
460 470 480 490 500
PYKCDDCGKD FSQRAHLTIH QRTHTGEKPY KCLECGKTFS HSSSLINHQR
510 520 530 540 550
VHTGEKPYIC NECGKTFSQS THLLQHQKIH TGKKPYKCNE CWKVFSQSTY
560 570 580 590 600
LIRHQRIHSG EKCYKCNECG KAFAHSSTLI QHQTTHTGEK SYICNICGKA
610 620 630 640 650
FSQSANLTQH HRTHTGEKPY KCSVCGKAFS QSVHLTQHQR IHNGEKPFKC
660 670 680 690 700
NICGKAYRQG ANLTQHQRIH TGEKPYKCNE CGKAFIYSSS LNQHQRTHTG
710 720 730 740 750
ERPYKCNECD KDFSQRTCLI QHQRIHTGEK PYACRICGKT FTQSTNLIQH
760
QRVHTGAKHR N
Length:761
Mass (Da):88,339
Last modified:December 11, 2019 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC8FF17233AEEC04E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JAV4C9JAV4_HUMAN
Zinc finger protein 287
ZNF287
57Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAG09702 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence AAI01488 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence AAI13364 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024207281K → T. Corresponds to variant dbSNP:rs7224723Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF217227 mRNA Translation: AAG09702.1 Different initiation.
AC127540 Genomic DNA No translation available.
BC101487 mRNA Translation: AAI01488.1 Different initiation.
BC113363 mRNA Translation: AAI13364.1 Different initiation.
CR457194 mRNA Translation: CAG33475.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11179.2

NCBI Reference Sequences

More...
RefSeqi
NP_001333096.1, NM_001346167.1
NP_001333097.1, NM_001346168.1
NP_001333098.1, NM_001346169.1
NP_065704.2, NM_020653.3
XP_011522270.1, XM_011523968.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000395824; ENSP00000379168; ENSG00000141040
ENST00000395825; ENSP00000379169; ENSG00000141040

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57336

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:57336

UCSC genome browser

More...
UCSCi
uc002gqi.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF217227 mRNA Translation: AAG09702.1 Different initiation.
AC127540 Genomic DNA No translation available.
BC101487 mRNA Translation: AAI01488.1 Different initiation.
BC113363 mRNA Translation: AAI13364.1 Different initiation.
CR457194 mRNA Translation: CAG33475.1
CCDSiCCDS11179.2
RefSeqiNP_001333096.1, NM_001346167.1
NP_001333097.1, NM_001346168.1
NP_001333098.1, NM_001346169.1
NP_065704.2, NM_020653.3
XP_011522270.1, XM_011523968.2

3D structure databases

SMRiQ9HBT7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi121490, 11 interactors
IntActiQ9HBT7, 1 interactor
STRINGi9606.ENSP00000379168

PTM databases

iPTMnetiQ9HBT7
PhosphoSitePlusiQ9HBT7

Genetic variation databases

BioMutaiZNF287
DMDMi20141038

Proteomic databases

jPOSTiQ9HBT7
MassIVEiQ9HBT7
MaxQBiQ9HBT7
PaxDbiQ9HBT7
PeptideAtlasiQ9HBT7
PRIDEiQ9HBT7
ProteomicsDBi81591

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
25338, 197 antibodies

The DNASU plasmid repository

More...
DNASUi
57336

Genome annotation databases

EnsembliENST00000395824; ENSP00000379168; ENSG00000141040
ENST00000395825; ENSP00000379169; ENSG00000141040
GeneIDi57336
KEGGihsa:57336
UCSCiuc002gqi.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57336
DisGeNETi57336

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF287
HGNCiHGNC:13502, ZNF287
HPAiENSG00000141040, Low tissue specificity
neXtProtiNX_Q9HBT7
OpenTargetsiENSG00000141040
PharmGKBiPA37788
VEuPathDBiHostDB:ENSG00000141040.14

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000162333
HOGENOMiCLU_002678_49_8_1
InParanoidiQ9HBT7
OMAiGFWKIHT
OrthoDBi1318335at2759
PhylomeDBiQ9HBT7
TreeFamiTF350843

Enzyme and pathway databases

PathwayCommonsiQ9HBT7
ReactomeiR-HSA-212436, Generic Transcription Pathway

Miscellaneous databases

PharosiQ9HBT7, Tdark

Protein Ontology

More...
PROi
PR:Q9HBT7
RNActiQ9HBT7, protein

Gene expression databases

BgeeiENSG00000141040, Expressed in adenohypophysis and 146 other tissues
ExpressionAtlasiQ9HBT7, baseline and differential
GenevisibleiQ9HBT7, HS

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
cd07936, SCAN, 1 hit
Gene3Di1.10.4020.10, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR003309, SCAN_dom
IPR038269, SCAN_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF02023, SCAN, 1 hit
PF00096, zf-C2H2, 14 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00431, SCAN, 1 hit
SM00355, ZnF_C2H2, 14 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS50804, SCAN_BOX, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 14 hits
PS50157, ZINC_FINGER_C2H2_2, 14 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN287_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9HBT7
Secondary accession number(s): Q6IAG1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: December 11, 2019
Last modified: June 2, 2021
This is version 170 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again