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Entry version 116 (11 Dec 2019)
Sequence version 2 (26 Feb 2008)
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Protein

Putative sodium-coupled neutral amino acid transporter 10

Gene

SLC38A10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Putative sodium-dependent amino acid/proton antiporter.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAmino-acid transport, Ion transport, Sodium transport, Transport
LigandSodium

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.18.6.16 the amino acid/auxin permease (aaap) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative sodium-coupled neutral amino acid transporter 10
Alternative name(s):
Solute carrier family 38 member 10
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PP1744
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000157637.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28237 SLC38A10

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
616525 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9HBR0

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Transmembranei36 – 58HelicalSequence analysisAdd BLAST23
Transmembranei84 – 104HelicalSequence analysisAdd BLAST21
Transmembranei120 – 140HelicalSequence analysisAdd BLAST21
Transmembranei153 – 173HelicalSequence analysisAdd BLAST21
Transmembranei229 – 249HelicalSequence analysisAdd BLAST21
Transmembranei272 – 292HelicalSequence analysisAdd BLAST21
Transmembranei323 – 343HelicalSequence analysisAdd BLAST21
Transmembranei345 – 365HelicalSequence analysisAdd BLAST21
Transmembranei378 – 398HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000157637

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162403738

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9HBR0 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC38A10

Domain mapping of disease mutations (DMDM)

More...
DMDMi
172045932

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003189751 – 1119Putative sodium-coupled neutral amino acid transporter 10Add BLAST1119

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei612PhosphoserineBy similarity1
Modified residuei772PhosphothreonineCombined sources1
Modified residuei802PhosphoserineCombined sources1
Modified residuei889PhosphoserineBy similarity1
Modified residuei965PhosphoserineCombined sources1
Modified residuei997PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9HBR0

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9HBR0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9HBR0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9HBR0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9HBR0

PeptideAtlas

More...
PeptideAtlasi
Q9HBR0

PRoteomics IDEntifications database

More...
PRIDEi
Q9HBR0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
81585 [Q9HBR0-1]
81586 [Q9HBR0-2]
81587 [Q9HBR0-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9HBR0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9HBR0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000157637 Expressed in 207 organ(s), highest expression level in right lobe of liver

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9HBR0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9HBR0 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA021374
HPA023161
HPA024631

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125874, 22 interactors

Protein interaction database and analysis system

More...
IntActi
Q9HBR0, 16 interactors

Molecular INTeraction database

More...
MINTi
Q9HBR0

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000363891

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9HBR0 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1305 Eukaryota
COG0814 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159369

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000154237

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9HBR0

KEGG Orthology (KO)

More...
KOi
K14996

Identification of Orthologs from Complete Genome Data

More...
OMAi
GQQGHRL

Database of Orthologous Groups

More...
OrthoDBi
1109791at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9HBR0

TreeFam database of animal gene trees

More...
TreeFami
TF320116

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013057 AA_transpt_TM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01490 Aa_trans, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9HBR0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTAAAASNWG LITNIVNSIV GVSVLTMPFC FKQCGIVLGA LLLVFCSWMT
60 70 80 90 100
HQSCMFLVKS ASLSKRRTYA GLAFHAYGKA GKMLVETSMI GLMLGTCIAF
110 120 130 140 150
YVVIGDLGSN FFARLFGFQV GGTFRMFLLF AVSLCIVLPL SLQRNMMASI
160 170 180 190 200
QSFSAMALLF YTVFMFVIVL SSLKHGLFSG QWLRRVSYVR WEGVFRCIPI
210 220 230 240 250
FGMSFACQSQ VLPTYDSLDE PSVKTMSSIF ASSLNVVTTF YVMVGFFGYV
260 270 280 290 300
SFTEATAGNV LMHFPSNLVT EMLRVGFMMS VAVGFPMMIL PCRQALSTLL
310 320 330 340 350
CEQQQKDGTF AAGGYMPPLR FKALTLSVVF GTMVGGILIP NVETILGLTG
360 370 380 390 400
ATMGSLICFI CPALIYKKIH KNALSSQVVL WVGLGVLVVS TVTTLSVSEE
410 420 430 440 450
VPEDLAEEAP GGRLGEAEGL MKVEAARLSA QDPVVAVAED GREKPKLPKE
460 470 480 490 500
REELEQAQIK GPVDVPGRED GKEAPEEAQL DRPGQGIAVP VGEAHRHEPP
510 520 530 540 550
VPHDKVVVDE GQDREVPEEN KPPSRHAGGK APGVQGQMAP PLPDSEREKQ
560 570 580 590 600
EPEQGEVGKR PGQAQALEEA GDLPEDPQKV PEADGQPAVQ PAKEDLGPGD
610 620 630 640 650
RGLHPRPQAV LSEQQNGLAV GGGEKAKGGP PPGNAAGDTG QPAEDSDHGG
660 670 680 690 700
KPPLPAEKPA PGPGLPPEPR EQRDVERAGG NQAASQLEEA GRAEMLDHAV
710 720 730 740 750
LLQVIKEQQV QQKRLLDQQE KLLAVIEEQH KEIHQQRQED EEDKPRQVEV
760 770 780 790 800
HQEPGAAVPR GQEAPEGKAR ETVENLPPLP LDPVLRAPGG RPAPSQDLNQ
810 820 830 840 850
RSLEHSEGPV GRDPAGPPDG GPDTEPRAAQ AKLRDGQKDA APRAAGTVKE
860 870 880 890 900
LPKGPEQVPV PDPAREAGGP EERLAEEFPG QSQDVTGGSQ DRKKPGKEVA
910 920 930 940 950
ATGTSILKEA NWLVAGPGAE TGDPRMKPKQ VSRDLGLAAD LPGGAEGAAA
960 970 980 990 1000
QPQAVLRQPE LRVISDGEQG GQQGHRLDHG GHLEMRKARG GDHVPVSHEQ
1010 1020 1030 1040 1050
PRGGEDAAVQ EPRQRPEPEL GLKRAVPGGQ RPDNAKPNRD LKLQAGSDLR
1060 1070 1080 1090 1100
RRRRDLGPHA EGQLAPRDGV IIGLNPLPDV QVNDLRGALD AQLRQAAGGA
1110
LQVVHSRQLR QAPGPPEES
Length:1,119
Mass (Da):119,762
Last modified:February 26, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF328CFEB6A5336D9
GO
Isoform 2 (identifier: Q9HBR0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     689-780: EAGRAEMLDH...ETVENLPPLP → GKASALQPPA...DYRFISLAPL
     781-1119: Missing.

Show »
Length:780
Mass (Da):83,324
Checksum:iE529A228C8842312
GO
Isoform 3 (identifier: Q9HBR0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-82: Missing.
     768-768: K → S
     769-1119: Missing.

Show »
Length:686
Mass (Da):73,978
Checksum:iF260EB0E42807634
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5H3T4F5H3T4_HUMAN
Putative sodium-coupled neutral ami...
SLC38A10
119Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L0Q8I3L0Q8_HUMAN
Putative sodium-coupled neutral ami...
SLC38A10
258Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YF92H0YF92_HUMAN
Putative sodium-coupled neutral ami...
SLC38A10
298Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YGS1H0YGS1_HUMAN
Putative sodium-coupled neutral ami...
SLC38A10
70Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAG17235 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC04027 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1071Missing in AAG17235 (PubMed:15498874).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_048126559K → R. Corresponds to variant dbSNP:rs35546507Ensembl.1
Natural variantiVAR_038927831A → G1 PublicationCorresponds to variant dbSNP:rs2725405Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0313231 – 82Missing in isoform 3. 1 PublicationAdd BLAST82
Alternative sequenceiVSP_031324689 – 780EAGRA…LPPLP → GKASALQPPASGPGSGSPLP QPWGDAQVILGSPARPPFSF QPPAEQTPRRAFCSLPISSL LSGNLLSALLPFKHLRHRHM ACDYRFISLAPL in isoform 2. 2 PublicationsAdd BLAST92
Alternative sequenceiVSP_031325768K → S in isoform 3. 1 Publication1
Alternative sequenceiVSP_031326769 – 1119Missing in isoform 3. 1 PublicationAdd BLAST351
Alternative sequenceiVSP_031327781 – 1119Missing in isoform 2. 2 PublicationsAdd BLAST339

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK093037 mRNA Translation: BAC04027.1 Different initiation.
AK128330 mRNA Translation: BAC87387.1
AC027601 Genomic DNA No translation available.
CH471099 Genomic DNA Translation: EAW89643.1
BC014642 mRNA Translation: AAH14642.1
AF217993 mRNA Translation: AAG17235.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11780.1 [Q9HBR0-2]
CCDS42397.1 [Q9HBR0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001033073.1, NM_001037984.2 [Q9HBR0-1]
NP_612637.1, NM_138570.3 [Q9HBR0-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000288439; ENSP00000288439; ENSG00000157637 [Q9HBR0-2]
ENST00000374759; ENSP00000363891; ENSG00000157637 [Q9HBR0-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
124565

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:124565

UCSC genome browser

More...
UCSCi
uc002jzz.3 human [Q9HBR0-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093037 mRNA Translation: BAC04027.1 Different initiation.
AK128330 mRNA Translation: BAC87387.1
AC027601 Genomic DNA No translation available.
CH471099 Genomic DNA Translation: EAW89643.1
BC014642 mRNA Translation: AAH14642.1
AF217993 mRNA Translation: AAG17235.1 Different initiation.
CCDSiCCDS11780.1 [Q9HBR0-2]
CCDS42397.1 [Q9HBR0-1]
RefSeqiNP_001033073.1, NM_001037984.2 [Q9HBR0-1]
NP_612637.1, NM_138570.3 [Q9HBR0-2]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi125874, 22 interactors
IntActiQ9HBR0, 16 interactors
MINTiQ9HBR0
STRINGi9606.ENSP00000363891

Protein family/group databases

TCDBi2.A.18.6.16 the amino acid/auxin permease (aaap) family

PTM databases

iPTMnetiQ9HBR0
PhosphoSitePlusiQ9HBR0

Polymorphism and mutation databases

BioMutaiSLC38A10
DMDMi172045932

Proteomic databases

EPDiQ9HBR0
jPOSTiQ9HBR0
MassIVEiQ9HBR0
MaxQBiQ9HBR0
PaxDbiQ9HBR0
PeptideAtlasiQ9HBR0
PRIDEiQ9HBR0
ProteomicsDBi81585 [Q9HBR0-1]
81586 [Q9HBR0-2]
81587 [Q9HBR0-3]

Genome annotation databases

EnsembliENST00000288439; ENSP00000288439; ENSG00000157637 [Q9HBR0-2]
ENST00000374759; ENSP00000363891; ENSG00000157637 [Q9HBR0-1]
GeneIDi124565
KEGGihsa:124565
UCSCiuc002jzz.3 human [Q9HBR0-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
124565
EuPathDBiHostDB:ENSG00000157637.12

GeneCards: human genes, protein and diseases

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GeneCardsi
SLC38A10
HGNCiHGNC:28237 SLC38A10
HPAiHPA021374
HPA023161
HPA024631
MIMi616525 gene
neXtProtiNX_Q9HBR0
OpenTargetsiENSG00000157637
PharmGKBiPA162403738

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1305 Eukaryota
COG0814 LUCA
GeneTreeiENSGT00940000159369
HOGENOMiHOG000154237
InParanoidiQ9HBR0
KOiK14996
OMAiGQQGHRL
OrthoDBi1109791at2759
PhylomeDBiQ9HBR0
TreeFamiTF320116

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SLC38A10 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
SLC38A10

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
124565
PharosiQ9HBR0 Tdark

Protein Ontology

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PROi
PR:Q9HBR0
RNActiQ9HBR0 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000157637 Expressed in 207 organ(s), highest expression level in right lobe of liver
ExpressionAtlasiQ9HBR0 baseline and differential
GenevisibleiQ9HBR0 HS

Family and domain databases

InterProiView protein in InterPro
IPR013057 AA_transpt_TM
PfamiView protein in Pfam
PF01490 Aa_trans, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS38AA_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9HBR0
Secondary accession number(s): Q6ZRC5, Q8NA99, Q96C66
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: December 11, 2019
This is version 116 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
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