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Entry version 128 (18 Sep 2019)
Sequence version 2 (17 Apr 2007)
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Protein

Radical S-adenosyl methionine domain-containing protein 1, mitochondrial

Gene

RSAD1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity (Probable). Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (By similarity).By similarity1 Publication

Miscellaneous

Might carry two S-adenosyl-L-methionine binding sites with only one binding to the iron-sulfur cluster.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei43S-adenosyl-L-methionine 1By similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi49Iron-sulfur (4Fe-4S-S-AdoMet)By similarity1
Metal bindingi53Iron-sulfur (4Fe-4S-S-AdoMet)By similarity1
Metal bindingi56Iron-sulfur (4Fe-4S-S-AdoMet)By similarity1
Binding sitei98S-adenosyl-L-methionine 1; via amide nitrogen and carbonyl oxygenBy similarity1
Binding sitei131S-adenosyl-L-methionine 1By similarity1
Binding sitei158S-adenosyl-L-methionine 2By similarity1
Binding sitei170S-adenosyl-L-methionine 2By similarity1
Binding sitei195S-adenosyl-L-methionine 2By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperone
Ligand4Fe-4S, Heme, Iron, Iron-sulfur, Metal-binding, S-adenosyl-L-methionine

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial
Alternative name(s):
Putative heme chaperone1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RSAD1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25634 RSAD1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9HA92

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000136444

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134945325

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9HA92

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RSAD1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
145566941

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 17MitochondrionSequence analysisAdd BLAST17
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000028460918 – 442Radical S-adenosyl methionine domain-containing protein 1, mitochondrialAdd BLAST425

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9HA92

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9HA92

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9HA92

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9HA92

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9HA92

PeptideAtlas

More...
PeptideAtlasi
Q9HA92

PRoteomics IDEntifications database

More...
PRIDEi
Q9HA92

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
4646
81387 [Q9HA92-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9HA92

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9HA92

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000136444 Expressed in 222 organ(s), highest expression level in ectocervix

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9HA92 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9HA92 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA022436
HPA022967

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
120598, 14 interactors

Protein interaction database and analysis system

More...
IntActi
Q9HA92, 8 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000258955

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9HA92

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni99 – 100S-adenosyl-L-methionine 2 bindingBy similarity2

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi12 – 18Poly-Ala7
Compositional biasi20 – 23Poly-Arg4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IF9E Eukaryota
COG0635 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011216

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000070024

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9HA92

Identification of Orthologs from Complete Genome Data

More...
OMAi
GPSAHSF

Database of Orthologous Groups

More...
OrthoDBi
1201842at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9HA92

TreeFam database of animal gene trees

More...
TreeFami
TF332416

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.30.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR034505 Coproporphyrinogen-III_oxidase
IPR006638 Elp3/MiaB/NifB
IPR010723 HemN_C
IPR004559 HemW-like
IPR007197 rSAM
IPR023404 rSAM_horseshoe

The PANTHER Classification System

More...
PANTHERi
PTHR13932 PTHR13932, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06969 HemN_C, 1 hit
PF04055 Radical_SAM, 1 hit

Structure-Function Linkage Database

More...
SFLDi
SFLDS00029 Radical_SAM, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00729 Elp3, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00539 hemN_rel, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9HA92-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MALPGARARG WAAAARAAQR RRRVENAGGS PSPEPAGRRA ALYVHWPYCE
60 70 80 90 100
KRCSYCNFNK YIPRRLEEAA MQKCLVTEAQ TLLRLSGVQR VESVFFGGGT
110 120 130 140 150
PSLASPHTVA AVLEAVAQAA HLPADLEVTL EANPTSAPGS RLAEFGAAGV
160 170 180 190 200
NRLSIGLQSL DDTELRLLGR THSACDALRT LAEARRLFPG RVSVDLMLGL
210 220 230 240 250
PAQQVGPWLG QLQELLHHCD DHLSLYQLSL ERGTALFAQV QRGALPAPDP
260 270 280 290 300
ELAAEMYQRG RAVLREAGFH QYEVSNFARN GALSTHNWTY WQCGQYLGVG
310 320 330 340 350
PGAHGRFMPQ GAGGHTREAR IQTLEPDNWM KEVMLFGHGT RKRVPLGRLE
360 370 380 390 400
LLEEVLALGL RTDVGITHQH WQQFEPQLTL WDVFGANKEV QELLERGLLQ
410 420 430 440
LDHRGLRCSW EGLAVLDSLL LTLLPQLQEA WQQRTPSPVP GG
Length:442
Mass (Da):48,714
Last modified:April 17, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA450E02F3AE2D554
GO
Isoform 2 (identifier: Q9HA92-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     46-158: Missing.
     282-307: ALSTHNWTYWQCGQYLGVGPGAHGRF → PMDDLCPRGLEATPGRLGSRHWSLTT
     308-441: Missing.

Note: No experimental confirmation available.
Show »
Length:195
Mass (Da):21,317
Checksum:iC0A73AD8C1CC9EC3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y9X4H0Y9X4_HUMAN
Radical S-adenosyl methionine domai...
RSAD1
85Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y934H0Y934_HUMAN
Radical S-adenosyl methionine domai...
RSAD1
195Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EKD3K7EKD3_HUMAN
Radical S-adenosyl methionine domai...
RSAD1
32Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti186R → G in BAB13962 (PubMed:14702039).Curated1
Sequence conflicti213Q → R in BAD96192 (Ref. 2) Curated1
Sequence conflicti272Y → C in BAB13962 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_031777119A → T1 PublicationCorresponds to variant dbSNP:rs2290862Ensembl.1
Natural variantiVAR_031778126L → S1 PublicationCorresponds to variant dbSNP:rs2290861Ensembl.1
Natural variantiVAR_061126354E → Q. Corresponds to variant dbSNP:rs9891176Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_05613046 – 158Missing in isoform 2. 1 PublicationAdd BLAST113
Alternative sequenceiVSP_056131282 – 307ALSTH…AHGRF → PMDDLCPRGLEATPGRLGSR HWSLTT in isoform 2. 1 PublicationAdd BLAST26
Alternative sequenceiVSP_056132308 – 441Missing in isoform 2. 1 PublicationAdd BLAST134

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK002026 mRNA Translation: BAA92043.1
AK022105 mRNA Translation: BAB13962.1
AK297655 mRNA Translation: BAG60022.1
AK222472 mRNA Translation: BAD96192.1
AC021491 Genomic DNA No translation available.
BC005854 mRNA Translation: AAH05854.4
BC050538 mRNA Translation: AAH50538.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11569.1 [Q9HA92-1]

NCBI Reference Sequences

More...
RefSeqi
NP_060816.1, NM_018346.2 [Q9HA92-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000258955; ENSP00000258955; ENSG00000136444 [Q9HA92-1]
ENST00000515221; ENSP00000424558; ENSG00000136444 [Q9HA92-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55316

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55316

UCSC genome browser

More...
UCSCi
uc002iqw.2 human [Q9HA92-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002026 mRNA Translation: BAA92043.1
AK022105 mRNA Translation: BAB13962.1
AK297655 mRNA Translation: BAG60022.1
AK222472 mRNA Translation: BAD96192.1
AC021491 Genomic DNA No translation available.
BC005854 mRNA Translation: AAH05854.4
BC050538 mRNA Translation: AAH50538.1
CCDSiCCDS11569.1 [Q9HA92-1]
RefSeqiNP_060816.1, NM_018346.2 [Q9HA92-1]

3D structure databases

SMRiQ9HA92
ModBaseiSearch...

Protein-protein interaction databases

BioGridi120598, 14 interactors
IntActiQ9HA92, 8 interactors
STRINGi9606.ENSP00000258955

PTM databases

iPTMnetiQ9HA92
PhosphoSitePlusiQ9HA92

Polymorphism and mutation databases

BioMutaiRSAD1
DMDMi145566941

Proteomic databases

EPDiQ9HA92
jPOSTiQ9HA92
MassIVEiQ9HA92
MaxQBiQ9HA92
PaxDbiQ9HA92
PeptideAtlasiQ9HA92
PRIDEiQ9HA92
ProteomicsDBi4646
81387 [Q9HA92-1]

Genome annotation databases

EnsembliENST00000258955; ENSP00000258955; ENSG00000136444 [Q9HA92-1]
ENST00000515221; ENSP00000424558; ENSG00000136444 [Q9HA92-2]
GeneIDi55316
KEGGihsa:55316
UCSCiuc002iqw.2 human [Q9HA92-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55316

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RSAD1
HGNCiHGNC:25634 RSAD1
HPAiHPA022436
HPA022967
neXtProtiNX_Q9HA92
OpenTargetsiENSG00000136444
PharmGKBiPA134945325

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IF9E Eukaryota
COG0635 LUCA
GeneTreeiENSGT00390000011216
HOGENOMiHOG000070024
InParanoidiQ9HA92
OMAiGPSAHSF
OrthoDBi1201842at2759
PhylomeDBiQ9HA92
TreeFamiTF332416

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
RSAD1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
55316
PharosiQ9HA92

Protein Ontology

More...
PROi
PR:Q9HA92

Gene expression databases

BgeeiENSG00000136444 Expressed in 222 organ(s), highest expression level in ectocervix
ExpressionAtlasiQ9HA92 baseline and differential
GenevisibleiQ9HA92 HS

Family and domain databases

Gene3Di3.80.30.20, 1 hit
InterProiView protein in InterPro
IPR034505 Coproporphyrinogen-III_oxidase
IPR006638 Elp3/MiaB/NifB
IPR010723 HemN_C
IPR004559 HemW-like
IPR007197 rSAM
IPR023404 rSAM_horseshoe
PANTHERiPTHR13932 PTHR13932, 1 hit
PfamiView protein in Pfam
PF06969 HemN_C, 1 hit
PF04055 Radical_SAM, 1 hit
SFLDiSFLDS00029 Radical_SAM, 1 hit
SMARTiView protein in SMART
SM00729 Elp3, 1 hit
TIGRFAMsiTIGR00539 hemN_rel, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRSAD1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9HA92
Secondary accession number(s): B4DMW0
, Q53HV8, Q86VC4, Q9BRY7, Q9NUS7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: April 17, 2007
Last modified: September 18, 2019
This is version 128 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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