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Entry version 156 (29 Sep 2021)
Sequence version 2 (24 May 2004)
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Protein

Ketosamine-3-kinase

Gene

FN3KRP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Ketosamine-3-kinase involved in protein deglycation by mediating phosphorylation of ribuloselysine and psicoselysine on glycated proteins, to generate ribuloselysine-3 phosphate and psicoselysine-3 phosphate, respectively (PubMed:14633848, PubMed:15137908).

Ribuloselysine-3 phosphate and psicoselysine-3 phosphate adducts are unstable and decompose under physiological conditions (PubMed:14633848, PubMed:15137908).

Not able to phosphorylate fructoselysine (PubMed:14633848).

2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=160 µM for deoxymorpholinopsicose1 Publication
  2. KM=270 µM for psicoselysine1 Publication
  3. KM=3.5 µM for deoxymorpholinoribulose1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei217Proton acceptorBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi89 – 91ATP1 Publication3

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:ENSG00000141560-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.7.1.171, 2681
2.7.1.172, 2681

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9HA64

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-163841, Gamma carboxylation, hypusine formation and arylsulfatase activation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ketosamine-3-kinase1 Publication (EC:2.7.1.1722 Publications)
Alternative name(s):
Fructosamine-3-kinase-related protein1 Publication
Short name:
FN3K-RP1 Publication
Short name:
FN3K-related protein1 Publication
Protein-psicosamine 3-kinase FN3KRPCurated (EC:2.7.1.-1 Publication)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FN3KRP1 PublicationImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25700, FN3KRP

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611683, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9HA64

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000141560

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
79672

Open Targets

More...
OpenTargetsi
ENSG00000141560

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA164720079

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9HA64, Tbio

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL4295947

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FN3KRP

Domain mapping of disease mutations (DMDM)

More...
DMDMi
47606765

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002163391 – 309Ketosamine-3-kinaseAdd BLAST309

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei20PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9HA64

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9HA64

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9HA64

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9HA64

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9HA64

PeptideAtlas

More...
PeptideAtlasi
Q9HA64

PRoteomics IDEntifications database

More...
PRIDEi
Q9HA64

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
81378

2D gel databases

REPRODUCTION-2DPAGE

More...
REPRODUCTION-2DPAGEi
IPI00099986

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q9HA64, 1 site, 1 O-linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9HA64

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9HA64

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed; except in skeletal muscle where it is expressed at very low level (PubMed:15331600). Expressed in erythrocytes (PubMed:15137908).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000141560, Expressed in right ovary and 221 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9HA64, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9HA64, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000141560, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
122797, 34 interactors

Protein interaction database and analysis system

More...
IntActi
Q9HA64, 10 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000269373

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9HA64, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9HA64

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The ATP-binding domain is structurally related to aminoglycoside phosphotransferase family.1 Publication

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the fructosamine kinase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3021, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005730

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_036517_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9HA64

Identification of Orthologs from Complete Genome Data

More...
OMAi
RECDIAM

Database of Orthologous Groups

More...
OrthoDBi
943202at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9HA64

TreeFam database of animal gene trees

More...
TreeFami
TF313452

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016477, Fructo-/Ketosamine-3-kinase
IPR011009, Kinase-like_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR12149, PTHR12149, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03881, Fructosamin_kin, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF006221, Ketosamine-3-kinase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56112, SSF56112, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

Q9HA64-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEELLRRELG CSSVRATGHS GGGCISQGRS YDTDQGRVFV KVNPKAEARR
60 70 80 90 100
MFEGEMASLT AILKTNTVKV PKPIKVLDAP GGGSVLVMEH MDMRHLSSHA
110 120 130 140 150
AKLGAQLADL HLDNKKLGEM RLKEAGTVGR GGGQEERPFV ARFGFDVVTC
160 170 180 190 200
CGYLPQVNDW QEDWVVFYAR QRIQPQMDMV EKESGDREAL QLWSALQLKI
210 220 230 240 250
PDLFRDLEII PALLHGDLWG GNVAEDSSGP VIFDPASFYG HSEYELAIAG
260 270 280 290 300
MFGGFSSSFY SAYHGKIPKA PGFEKRLQLY QLFHYLNHWN HFGSGYRGSS

LNIMRNLVK
Length:309
Mass (Da):34,412
Last modified:May 24, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEE6101C5BB2A7FF3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
I3L378I3L378_HUMAN
Protein-ribulosamine 3-kinase
FN3KRP
124Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L139I3L139_HUMAN
Protein-ribulosamine 3-kinase
FN3KRP
145Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L2G3I3L2G3_HUMAN
Protein-ribulosamine 3-kinase
FN3KRP
127Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L3W5I3L3W5_HUMAN
Protein-ribulosamine 3-kinase
FN3KRP
102Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L407I3L407_HUMAN
Ketosamine-3-kinase
FN3KRP
56Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L2K8I3L2K8_HUMAN
Ketosamine-3-kinase
FN3KRP
50Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAB66566 differs from that shown. Reason: Erroneous termination. Truncated C-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti129G → W in CAB66566 (PubMed:11230166).Curated1
Sequence conflicti265G → C in AAH01458 (PubMed:15489334).Curated1
Sequence conflicti278Q → R in BAB13992 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03405757A → V. Corresponds to variant dbSNP:rs3748811Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY360465 mRNA Translation: AAQ72344.1
AL136631 mRNA Translation: CAB66566.1 Sequence problems.
AK022233 mRNA Translation: BAB13992.1
BC001458 mRNA Translation: AAH01458.2
BC007611 mRNA Translation: AAH07611.1
BC014408 mRNA Translation: AAH14408.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11817.1

NCBI Reference Sequences

More...
RefSeqi
NP_078895.2, NM_024619.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000269373; ENSP00000269373; ENSG00000141560

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79672

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79672

UCSC genome browser

More...
UCSCi
uc002kfu.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY360465 mRNA Translation: AAQ72344.1
AL136631 mRNA Translation: CAB66566.1 Sequence problems.
AK022233 mRNA Translation: BAB13992.1
BC001458 mRNA Translation: AAH01458.2
BC007611 mRNA Translation: AAH07611.1
BC014408 mRNA Translation: AAH14408.1
CCDSiCCDS11817.1
RefSeqiNP_078895.2, NM_024619.3

3D structure databases

SMRiQ9HA64
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi122797, 34 interactors
IntActiQ9HA64, 10 interactors
STRINGi9606.ENSP00000269373

Chemistry databases

ChEMBLiCHEMBL4295947

PTM databases

GlyGeniQ9HA64, 1 site, 1 O-linked glycan (1 site)
iPTMnetiQ9HA64
PhosphoSitePlusiQ9HA64

Genetic variation databases

BioMutaiFN3KRP
DMDMi47606765

2D gel databases

REPRODUCTION-2DPAGEiIPI00099986

Proteomic databases

EPDiQ9HA64
jPOSTiQ9HA64
MassIVEiQ9HA64
MaxQBiQ9HA64
PaxDbiQ9HA64
PeptideAtlasiQ9HA64
PRIDEiQ9HA64
ProteomicsDBi81378

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
33041, 104 antibodies

The DNASU plasmid repository

More...
DNASUi
79672

Genome annotation databases

EnsembliENST00000269373; ENSP00000269373; ENSG00000141560
GeneIDi79672
KEGGihsa:79672
UCSCiuc002kfu.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79672
DisGeNETi79672

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FN3KRP
HGNCiHGNC:25700, FN3KRP
HPAiENSG00000141560, Low tissue specificity
MIMi611683, gene
neXtProtiNX_Q9HA64
OpenTargetsiENSG00000141560
PharmGKBiPA164720079
VEuPathDBiHostDB:ENSG00000141560

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3021, Eukaryota
GeneTreeiENSGT00390000005730
HOGENOMiCLU_036517_0_1_1
InParanoidiQ9HA64
OMAiRECDIAM
OrthoDBi943202at2759
PhylomeDBiQ9HA64
TreeFamiTF313452

Enzyme and pathway databases

BioCyciMetaCyc:ENSG00000141560-MONOMER
BRENDAi2.7.1.171, 2681
2.7.1.172, 2681
PathwayCommonsiQ9HA64
ReactomeiR-HSA-163841, Gamma carboxylation, hypusine formation and arylsulfatase activation

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
79672, 0 hits in 1014 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
FN3KRP, human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
FN3KRP

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
79672
PharosiQ9HA64, Tbio

Protein Ontology

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PROi
PR:Q9HA64
RNActiQ9HA64, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000141560, Expressed in right ovary and 221 other tissues
ExpressionAtlasiQ9HA64, baseline and differential
GenevisibleiQ9HA64, HS

Family and domain databases

InterProiView protein in InterPro
IPR016477, Fructo-/Ketosamine-3-kinase
IPR011009, Kinase-like_dom_sf
PANTHERiPTHR12149, PTHR12149, 1 hit
PfamiView protein in Pfam
PF03881, Fructosamin_kin, 1 hit
PIRSFiPIRSF006221, Ketosamine-3-kinase, 1 hit
SUPFAMiSSF56112, SSF56112, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKT3K_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9HA64
Secondary accession number(s): Q969F4, Q9H0U7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: May 24, 2004
Last modified: September 29, 2021
This is version 156 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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