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UniProtKB - Q9H9P2 (CHODL_HUMAN)

Entry version 169 (22 Apr 2020)
Sequence version 2 (18 Oct 2001)
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Protein

Chondrolectin

Gene

CHODL

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in the development of the nervous system such as in neurite outgrowth and elongation. May be involved in motor axon growth and guidance.By similarity

Miscellaneous

A protein of the expected size has been detected by antibody binding and Western blot in at least one of the analyzed tissues or cells.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

  • muscle organ development Source: HGNC-UCL
  • positive regulation of axonogenesis Source: GO_Central
Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processNeurogenesis
LigandLectin

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Chondrolectin
Alternative name(s):
Transmembrane protein MT75
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CHODL
Synonyms:C21orf68
ORF Names:PRED12, UNQ872/PRO1890
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:17807 CHODL

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		607247 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9H9P2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini22 – 216ExtracellularSequence analysisAdd BLAST195
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei217 – 237HelicalSequence analysisAdd BLAST21
Topological domaini238 – 273CytoplasmicSequence analysisAdd BLAST36

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		140578

Open Targets

More...OpenTargetsi		ENSG00000154645

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA26475

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9H9P2 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CHODL

Domain mapping of disease mutations (DMDM)

More...DMDMi		18202949

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 21Sequence analysisAdd BLAST21
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001741522 – 273ChondrolectinAdd BLAST252

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi61 ↔ 178PROSITE-ProRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi86N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi144 ↔ 170PROSITE-ProRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-glycosylated.

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9H9P2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9H9P2

PeptideAtlas

More...PeptideAtlasi		Q9H9P2

PRoteomics IDEntifications database

More...PRIDEi		Q9H9P2

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		81335 [Q9H9P2-1]
81336 [Q9H9P2-2]
81337 [Q9H9P2-3]
81338 [Q9H9P2-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9H9P2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9H9P2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Found in spleen, testis, prostate and fetal liver. Expression limited to vascular muscle of testis, smooth muscle of prostate stroma, heart muscle, skeletal muscle, crypts of small intestine, and red pulp of spleen. B lymphocytes express isoform 2 only; peripheral blood T lymphocytes express isoform 3 only; granulocytes and monocytes express neither isoform 2 nor isoform 3. During development of T lymphocytes, bone marrow progenitor cells express isoform 2 only; thymocytes at different stages of maturation express predominantly isoform 2 and weakly isoform 3, and mature thymocytes express only isoform 2.3 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000154645 Expressed in kidney and 127 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9H9P2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9H9P2 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000154645 Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with RABGGTB.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Show more details

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		Q9H9P2, 10 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000299295

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9H9P2 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9H9P2

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 179C-type lectinPROSITE-ProRule annotationAdd BLAST145

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4297 Eukaryota
ENOG410XPJ1 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00390000001844

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_045492_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9H9P2

KEGG Orthology (KO)

More...KOi		K10078

Identification of Orthologs from Complete Genome Data

More...OMAi		SGQKVCY

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9H9P2

TreeFam database of animal gene trees

More...TreeFami		TF330715

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.10.100.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR016187 CTDL_fold

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00059 Lectin_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00034 CLECT, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF56436 SSF56436, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50041 C_TYPE_LECTIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative promoter usage and alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H9P2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSRVVSLLLG AALLCGHGAF CRRVVSGQKV CFADFKHPCY KMAYFHELSS 
        60         70         80         90        100
RVSFQEARLA CESEGGVLLS LENEAEQKLI ESMLQNLTKP GTGISDGDFW 
       110        120        130        140        150
IGLWRNGDGQ TSGACPDLYQ WSDGSNSQYR NWYTDEPSCG SEKCVVMYHQ 
       160        170        180        190        200
PTANPGLGGP YLYQWNDDRC NMKHNYICKY EPEINPTAPV EKPYLTNQPG 
       210        220        230        240        250
DTHQNVVVTE AGIIPNLIYV VIPTIPLLLL ILVAFGTCCF QMLHKSKGRT 
       260        270 
KTSPNQSTLW ISKSTRKESG MEV
Note: Produced by alternative promoter usage.
Length:273
Mass (Da):30,431
Last modified:October 18, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF4890AAFB572A311
GO
Isoform 2 (identifier: Q9H9P2-2) [UniParc]FASTAAdd to basket
Also known as: CHODLF

The sequence of this isoform differs from the canonical sequence as follows:
     1-41: Missing.

Note: roduced by alternative promoter usage.Curated
Show »
Length:232
Mass (Da):25,979
Checksum:i98B80BBDF7C7F439
GO
Isoform 3 (identifier: Q9H9P2-3) [UniParc]FASTAAdd to basket
Also known as: CHODLFdeltaE

The sequence of this isoform differs from the canonical sequence as follows:
     1-41: Missing.
     212-273: GIIPNLIYVV...STRKESGMEV → VKEEQKLVQT...EITKDLQDEL

Note: Produced by alternative splicing of isoform 2.Curated
Show »
Length:236
Mass (Da):27,157
Checksum:i5110DE6A86472CD9
GO
Isoform 4 (identifier: Q9H9P2-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-27: MSRVVSLLLGAALLCGHGAFCRRVVSG → MTAGSAHS

Note: Produced by alternative splicing of isoform 1.Curated
Show »
Length:254
Mass (Da):28,418
Checksum:iCD50D9959326678D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0C4DFS2A0A0C4DFS2_HUMAN
Chondrolectin
CHODL
236Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti56E → G in AAP43902 (PubMed:12621022).Curated1
Sequence conflicti159G → S in AAP43902 (PubMed:12621022).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0172751 – 41Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST41
Alternative sequenceiVSP_0433001 – 27MSRVV…RVVSG → MTAGSAHS in isoform 4. 1 PublicationAdd BLAST27
Alternative sequenceiVSP_017276212 – 273GIIPN…SGMEV → VKEEQKLVQTSLHCGFQRVP EKKAAWKYNNSLTWFQNFVI LDLYKEWHQNNSLEWLEITK DLQDEL in isoform 3. 1 PublicationAdd BLAST62

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF257472 mRNA Translation: AAL05981.1
AF523313 mRNA Translation: AAP43902.1
AF523314 mRNA Translation: AAP43903.1
AF523315 mRNA Translation: AAP43904.1
AY358608 mRNA Translation: AAQ88971.1
AK022689 mRNA Translation: BAB14181.1
AK296009 mRNA Translation: BAG58780.1
AK313725 mRNA Translation: BAG36467.1
AF130417 Genomic DNA No translation available.
AL078474 Genomic DNA No translation available.
AL109761 Genomic DNA No translation available.
AL163217 Genomic DNA Translation: CAB90388.1
AP000404 Genomic DNA No translation available.
AP000656 Genomic DNA No translation available.
AP000745 Genomic DNA No translation available.
AP000998 Genomic DNA No translation available.
CH471079 Genomic DNA Translation: EAX10018.1
BC009418 mRNA Translation: AAH09418.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS13570.1 [Q9H9P2-1]
CCDS56208.1 [Q9H9P2-4]
CCDS56209.1 [Q9H9P2-2]
CCDS56210.1 [Q9H9P2-3]

NCBI Reference Sequences

More...RefSeqi		NP_001191103.1, NM_001204174.1 [Q9H9P2-4]
NP_001191104.1, NM_001204175.1 [Q9H9P2-2]
NP_001191105.1, NM_001204176.1 [Q9H9P2-2]
NP_001191106.1, NM_001204177.1
NP_001191107.1, NM_001204178.1
NP_079220.2, NM_024944.2 [Q9H9P2-1]
XP_011527759.1, XM_011529457.2 [Q9H9P2-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000299295; ENSP00000299295; ENSG00000154645 [Q9H9P2-1]
ENST00000400127; ENSP00000382992; ENSG00000154645 [Q9H9P2-2]
ENST00000400128; ENSP00000382993; ENSG00000154645 [Q9H9P2-2]
ENST00000543733; ENSP00000443566; ENSG00000154645 [Q9H9P2-4]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		140578

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:140578

UCSC genome browser

More...UCSCi		uc002ykr.5 human [Q9H9P2-1]

Keywords - Coding sequence diversityi

Alternative promoter usage, Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Functional Glycomics Gateway - Glycan Binding

Chondrolectin

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF257472 mRNA Translation: AAL05981.1
AF523313 mRNA Translation: AAP43902.1
AF523314 mRNA Translation: AAP43903.1
AF523315 mRNA Translation: AAP43904.1
AY358608 mRNA Translation: AAQ88971.1
AK022689 mRNA Translation: BAB14181.1
AK296009 mRNA Translation: BAG58780.1
AK313725 mRNA Translation: BAG36467.1
AF130417 Genomic DNA No translation available.
AL078474 Genomic DNA No translation available.
AL109761 Genomic DNA No translation available.
AL163217 Genomic DNA Translation: CAB90388.1
AP000404 Genomic DNA No translation available.
AP000656 Genomic DNA No translation available.
AP000745 Genomic DNA No translation available.
AP000998 Genomic DNA No translation available.
CH471079 Genomic DNA Translation: EAX10018.1
BC009418 mRNA Translation: AAH09418.1
CCDSiCCDS13570.1 [Q9H9P2-1]
CCDS56208.1 [Q9H9P2-4]
CCDS56209.1 [Q9H9P2-2]
CCDS56210.1 [Q9H9P2-3]
RefSeqiNP_001191103.1, NM_001204174.1 [Q9H9P2-4]
NP_001191104.1, NM_001204175.1 [Q9H9P2-2]
NP_001191105.1, NM_001204176.1 [Q9H9P2-2]
NP_001191106.1, NM_001204177.1
NP_001191107.1, NM_001204178.1
NP_079220.2, NM_024944.2 [Q9H9P2-1]
XP_011527759.1, XM_011529457.2 [Q9H9P2-2]

3D structure databases

SMRiQ9H9P2
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ9H9P2, 10 interactors
STRINGi9606.ENSP00000299295

PTM databases

iPTMnetiQ9H9P2
PhosphoSitePlusiQ9H9P2

Polymorphism and mutation databases

BioMutaiCHODL
DMDMi18202949

Proteomic databases

MassIVEiQ9H9P2
PaxDbiQ9H9P2
PeptideAtlasiQ9H9P2
PRIDEiQ9H9P2
ProteomicsDBi81335 [Q9H9P2-1]
81336 [Q9H9P2-2]
81337 [Q9H9P2-3]
81338 [Q9H9P2-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		2518 128 antibodies

The DNASU plasmid repository

More...DNASUi		140578

Genome annotation databases

EnsembliENST00000299295; ENSP00000299295; ENSG00000154645 [Q9H9P2-1]
ENST00000400127; ENSP00000382992; ENSG00000154645 [Q9H9P2-2]
ENST00000400128; ENSP00000382993; ENSG00000154645 [Q9H9P2-2]
ENST00000543733; ENSP00000443566; ENSG00000154645 [Q9H9P2-4]
GeneIDi140578
KEGGihsa:140578
UCSCiuc002ykr.5 human [Q9H9P2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		140578
DisGeNETi140578

GeneCards: human genes, protein and diseases

More...GeneCardsi		CHODL
HGNCiHGNC:17807 CHODL
HPAiENSG00000154645 Tissue enriched (testis)
MIMi607247 gene
neXtProtiNX_Q9H9P2
OpenTargetsiENSG00000154645
PharmGKBiPA26475

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4297 Eukaryota
ENOG410XPJ1 LUCA
GeneTreeiENSGT00390000001844
HOGENOMiCLU_045492_1_0_1
InParanoidiQ9H9P2
KOiK10078
OMAiSGQKVCY
PhylomeDBiQ9H9P2
TreeFamiTF330715

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		CHODL human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		CHODL

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		140578
PharosiQ9H9P2 Tbio

Protein Ontology

More...PROi		PR:Q9H9P2
RNActiQ9H9P2 protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000154645 Expressed in kidney and 127 other tissues
ExpressionAtlasiQ9H9P2 baseline and differential
GenevisibleiQ9H9P2 HS

Family and domain databases

Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR016187 CTDL_fold
PfamiView protein in Pfam
PF00059 Lectin_C, 1 hit
SMARTiView protein in SMART
SM00034 CLECT, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit
PROSITEiView protein in PROSITE
PS50041 C_TYPE_LECTIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCHODL_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H9P2
Secondary accession number(s): B2R9C0
, B4DJB8, Q7Z798, Q7Z799, Q7Z7A0, Q9HCY3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: October 18, 2001
Last modified: April 22, 2020
This is version 169 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
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