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UniProtKB - Q9H9K5 (MER34_HUMAN)

Entry version 119 (17 Jun 2020)
Sequence version 1 (01 Mar 2001)
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Protein

Endogenous retroviral envelope protein HEMO

Gene

ERVMER34-1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Endogenous envelope proteins originate from retroviral envelope proteins, which mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Endogenous retroviral envelope protein HEMOCurated
Alternative name(s):
Endogenous retrovirus group MER34 member 1 Env polyproteinCurated
HERV-MER_4q12 provirus ancestral Env polyprotein
Human endogenous MER34 (medium-reiteration-frequency-family-34) open reading frame1 Publication
Human endogenous MER34 ORF1 Publication
Short name:
HEMO1 Publication
Cleaved into the following chain:
Endogenous retroviral envelope protein HEMO, secreted formCurated
Alternative name(s):
Endogenous retroviral envelope protein HEMO, 48 kDa form
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ERVMER34-1Imported
Synonyms:HEMO1 Publication
ORF Names:LP9056
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000226887.7

Human Gene Nomenclature Database

More...HGNCi		HGNC:42970 ERVMER34-1

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9H9K5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini27 – 488ExtracellularSequence analysisAdd BLAST462
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei489 – 509HelicalSequence analysisAdd BLAST21
Topological domaini510 – 563CytoplasmicSequence analysisAdd BLAST54

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell membrane, Membrane, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi352 – 355CTQG → RTKR: Introduction of a furin cleavage site, promoting proteolytic cleavage of the protein by furin and release in the extracellular medium. 1 Publication4
Mutagenesisi433 – 563Missing : Promotes release in the extracellular medium. 1 PublicationAdd BLAST131
Mutagenesisi472 – 563Missing : Promotes release in the extracellular medium. 1 PublicationAdd BLAST92
Mutagenesisi489 – 563Missing : Promotes release in the extracellular medium. 1 PublicationAdd BLAST75

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000226887

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9H9K5 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ERVMER34-1

Domain mapping of disease mutations (DMDM)

More...DMDMi		74734033

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 261 PublicationAdd BLAST26
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000034135227 – 563Endogenous retroviral envelope protein HEMOAdd BLAST537
ChainiPRO_000044380027 – 432Endogenous retroviral envelope protein HEMO, secreted form1 PublicationAdd BLAST406

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi122N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi192N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-glycosylated.1 Publication
Cleaved by some metalloproteinase at 432-Gln-Arg-433 (mainly) or 433-Arg-Gln-434, leading to release the secreted form (Endogenous retroviral envelope protein HEMO, secreted form) in the extracellular medium.1 Publication

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9H9K5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9H9K5

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9H9K5

PeptideAtlas

More...PeptideAtlasi		Q9H9K5

PRoteomics IDEntifications database

More...PRIDEi		Q9H9K5

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		81327

Consortium for Top Down Proteomics

More...TopDownProteomicsi		Q9H9K5

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9H9K5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9H9K5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed at high level in the placenta and stem cells (at protein level) (PubMed:28739914). Also expressed in the kidney but at a lower level (PubMed:28739914). Endogenous retroviral envelope protein HEMO, secreted form: Present in the blood of pregnant women (at protein level) (PubMed:28739914).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000226887 Expressed in chorionic villus and 88 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9H9K5 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000226887 Group enriched (parathyroid gland, placenta)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000460602

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9H9K5 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi171 – 174Poly-Asp4

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the gamma type-C retroviral envelope protein family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410J8IS Eukaryota
ENOG4111C12 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00870000136875

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_483911_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9H9K5

Identification of Orthologs from Complete Genome Data

More...OMAi		GKWRCAD

Database of Orthologous Groups

More...OrthoDBi		389221at2759

TreeFam database of animal gene trees

More...TreeFami		TF344098

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR018154 TLV/ENV_coat_polyprotein

The PANTHER Classification System

More...PANTHERi		PTHR10424 PTHR10424, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9H9K5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSLSNYALL QLTLTAFLTI LVQPQHLLAP VFRTLSILTN QSNCWLCEHL 
        60         70         80         90        100
DNAEQPELVF VPASASTWWT YSGQWMYERV WYPQAEVQNH STSSYRKVTW 
       110        120        130        140        150
HWEASMEAQG LSFAQVRLLE GNFSLCVENK NGSGPFLGNI PKQYCNQILW 
       160        170        180        190        200
FDSTDGTFMP SIDVTNESRN DDDDTSVCLG TRQCSWFAGC TNRTWNSSAV 
       210        220        230        240        250
PLIGLPNTQD YKWVDRNSGL TWSGNDTCLY SCQNQTKGLL YQLFRNLFCS 
       260        270        280        290        300
YGLTEAHGKW RCADASITND KGHDGHRTPT WWLTGSNLTL SVNNSGLFFL 
       310        320        330        340        350
CGNGVYKGFP PKWSGRCGLG YLVPSLTRYL TLNASQITNL RSFIHKVTPH 
       360        370        380        390        400
RCTQGDTDNP PLYCNPKDNS TIRALFPSLG TYDLEKAILN ISKAMEQEFS 
       410        420        430        440        450
ATKQTLEAHQ SKVSSLASAS RKDHVLDIPT TQRQTACGTV GKQCCLYINY 
       460        470        480        490        500
SEEIKSNIQR LHEASENLKN VPLLDWQGIF AKVGDWFRSW GYVLLIVLFC 
       510        520        530        540        550
LFIFVLIYVR VFRKSRRSLN SQPLNLALSP QQSAQLLVSE TSCQVSNRAM 
       560 
KGLTTHQYDT SLL
Length:563
Mass (Da):63,547
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD8D0B75216FDF8B7
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH69998 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti34T → A in AAH69998 (PubMed:15489334).Curated1
Sequence conflicti81W → R in AAH67529 (PubMed:15489334).Curated1
Sequence conflicti418S → P in AAH67529 (PubMed:15489334).Curated1
Sequence conflicti434Q → R in AAH67529 (PubMed:15489334).Curated1
Sequence conflicti459Q → H in AAH69998 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY189288 mRNA Translation: AAO86732.1
AK022746 mRNA Translation: BAB14220.1
AK095318 mRNA Translation: BAG53026.1
CH471057 Genomic DNA Translation: EAX05439.1
BC067526 mRNA Translation: AAH67526.1
BC067528 mRNA Translation: AAH67528.1
BC067529 mRNA Translation: AAH67529.1
BC069998 mRNA Translation: AAH69998.1 Frameshift.

NCBI Reference Sequences

More...RefSeqi		NP_001229619.1, NM_001242690.1
NP_078810.1, NM_024534.5

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000440542; ENSP00000460255; ENSG00000226887
ENST00000443173; ENSP00000460602; ENSG00000226887

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100288413

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:100288413

UCSC genome browser

More...UCSCi		uc003gzr.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY189288 mRNA Translation: AAO86732.1
AK022746 mRNA Translation: BAB14220.1
AK095318 mRNA Translation: BAG53026.1
CH471057 Genomic DNA Translation: EAX05439.1
BC067526 mRNA Translation: AAH67526.1
BC067528 mRNA Translation: AAH67528.1
BC067529 mRNA Translation: AAH67529.1
BC069998 mRNA Translation: AAH69998.1 Frameshift.
RefSeqiNP_001229619.1, NM_001242690.1
NP_078810.1, NM_024534.5

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi9606.ENSP00000460602

PTM databases

iPTMnetiQ9H9K5
PhosphoSitePlusiQ9H9K5

Polymorphism and mutation databases

BioMutaiERVMER34-1
DMDMi74734033

Proteomic databases

EPDiQ9H9K5
MassIVEiQ9H9K5
PaxDbiQ9H9K5
PeptideAtlasiQ9H9K5
PRIDEiQ9H9K5
ProteomicsDBi81327
TopDownProteomicsiQ9H9K5

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		63827 4 antibodies

Genome annotation databases

EnsembliENST00000440542; ENSP00000460255; ENSG00000226887
ENST00000443173; ENSP00000460602; ENSG00000226887
GeneIDi100288413
KEGGihsa:100288413
UCSCiuc003gzr.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		100288413
EuPathDBiHostDB:ENSG00000226887.7

GeneCards: human genes, protein and diseases

More...GeneCardsi		ERVMER34-1
HGNCiHGNC:42970 ERVMER34-1
HPAiENSG00000226887 Group enriched (parathyroid gland, placenta)
neXtProtiNX_Q9H9K5
OpenTargetsiENSG00000226887

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410J8IS Eukaryota
ENOG4111C12 LUCA
GeneTreeiENSGT00870000136875
HOGENOMiCLU_483911_0_0_1
InParanoidiQ9H9K5
OMAiGKWRCAD
OrthoDBi389221at2759
TreeFamiTF344098

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		100288413 1 hit in 37 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ERVMER34-1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		100288413
PharosiQ9H9K5 Tdark

Protein Ontology

More...PROi		PR:Q9H9K5
RNActiQ9H9K5 protein

Gene expression databases

BgeeiENSG00000226887 Expressed in chorionic villus and 88 other tissues
GenevisibleiQ9H9K5 HS

Family and domain databases

InterProiView protein in InterPro
IPR018154 TLV/ENV_coat_polyprotein
PANTHERiPTHR10424 PTHR10424, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMER34_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H9K5
Secondary accession number(s): B3KTB4, Q0P5R3, Q6NWN0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: March 1, 2001
Last modified: June 17, 2020
This is version 119 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

ERV, Reference proteome, Transposable element

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
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