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UniProtKB - Q9H9F9 (ARP5_HUMAN)

Entry version 146 (07 Apr 2021)
Sequence version 2 (25 Jul 2006)
Previous versions | rss
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Protein

Actin-related protein 5

Gene

ACTR5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Involved in DNA double-strand break repair and UV-damage excision repair.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9H9F9

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-5689603, UCH proteinases
R-HSA-5696394, DNA Damage Recognition in GG-NER

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9H9F9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Actin-related protein 5
Short name:
hARP5
Alternative name(s):
Sarcoma antigen NY-SAR-16
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ACTR5
Synonyms:ARP5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:14671, ACTR5

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9H9F9

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000101442.9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		79913

Open Targets

More...OpenTargetsi		ENSG00000101442

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA24490

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9H9F9, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ACTR5

Domain mapping of disease mutations (DMDM)

More...DMDMi		110832751

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002478421 – 607Actin-related protein 5Add BLAST607

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki283Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9H9F9

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9H9F9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9H9F9

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9H9F9

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9H9F9

PeptideAtlas

More...PeptideAtlasi		Q9H9F9

PRoteomics IDEntifications database

More...PRIDEi		Q9H9F9

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		81319

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9H9F9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9H9F9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000101442, Expressed in epithelium of mammary gland and 217 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9H9F9, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000101442, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the helicase ATP-binding and the helicase C-terminal domain of INO80.

Interacts with DDB1.

Interacts with ACTR8; the interaction is observed in asynchronous (interphase) cells but not in metaphase-arrested cells indicative for a possible dissociation of the INO80 complex in mitotic cells.

5 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		122993, 53 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-846, INO80 chromatin remodeling complex

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		Q9H9F9

Database of interacting proteins

More...DIPi		DIP-34297N

Protein interaction database and analysis system

More...IntActi		Q9H9F9, 49 interactors

Molecular INTeraction database

More...MINTi		Q9H9F9

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000243903

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9H9F9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9H9F9

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili288 – 327Sequence analysisAdd BLAST40
Coiled coili355 – 384Sequence analysisAdd BLAST30

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the actin family. ARP5 subfamily.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0681, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00720000108866

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_008246_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9H9F9

Identification of Orthologs from Complete Genome Data

More...OMAi		ITNWNHQ

Database of Orthologous Groups

More...OrthoDBi		344271at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9H9F9

TreeFam database of animal gene trees

More...TreeFami		TF324227

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004000, Actin
IPR004001, Actin_CS
IPR027664, Arp5
IPR043129, ATPase_NBD

The PANTHER Classification System

More...PANTHERi		PTHR11937, PTHR11937, 2 hits
PTHR11937:SF16, PTHR11937:SF16, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00022, Actin, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00268, ACTIN, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53067, SSF53067, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00432, ACTINS_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9H9F9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAANVFPFRD ARAAPDPVLE AGPVAHGPLP VPLVLDNGSF QVRAGWACPG 
        60         70         80         90        100
QDPGPEPRLQ FRAVCARGRG GARGASGPQV GNALGSLEPL RWMLRSPFDR 
       110        120        130        140        150
NVPVNLELQE LLLDYSFQHL GVSSQGCVDH PIVLTEAVCN PLYSRQMMSE 
       160        170        180        190        200
LLFECYGIPK VAYGIDSLFS FYHNKPKNSM CSGLIISSGY QCTHVLPILE 
       210        220        230        240        250
GRLDAKNCKR INLGGSQAAG YLQRLLQLKY PGHLAAITLS RMEEILHEHS 
       260        270        280        290        300
YIAEDYVEEL HKWRCPDYYE NNVHKMQLPF SSKLLGSTLT SEEKQERRQQ 
       310        320        330        340        350
QLRRLQELNA RRREEKLQLD QERLDRLLYV QELLEDGQMD QFHKALIELN 
       360        370        380        390        400
MDSPEELQSY IQKLSIAVEQ AKQKILQAEV NLEVDVVDSK PETPDLEQLE 
       410        420        430        440        450
PSLEDVESMN DFDPLFSEET PGVEKPVTTV QPVFNLAAYH QLFVGTERIR 
       460        470        480        490        500
APEIIFQPSL IGEEQAGIAE TLQYILDRYP KDIQEMLVQN VFLTGGNTMY 
       510        520        530        540        550
PGMKARMEKE LLEMRPFRSS FQVQLASNPV LDAWYGARDW ALNHLDDNEV 
       560        570        580        590        600
WITRKEYEEK GGEYLKEHCA SNIYVPIRLP KQASRSSDAQ ASSKGSAAGG 

GGAGEQA
Length:607
Mass (Da):68,297
Last modified:July 25, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDA3E50AE37BCC363
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAO65164 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti69 – 70RG → AR in AAO65164 (PubMed:12601173).Curated2
Sequence conflicti481K → E in BAB14270 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_027158298R → L1 PublicationCorresponds to variant dbSNP:rs17853829Ensembl.1
Natural variantiVAR_048189461I → L. Corresponds to variant dbSNP:rs35805905Ensembl.1
Natural variantiVAR_027159483I → V1 PublicationCorresponds to variant dbSNP:rs2245231Ensembl.1
Natural variantiVAR_027160580P → L. Corresponds to variant dbSNP:rs3752289Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK022847 mRNA Translation: BAB14270.1
AL133519 Genomic DNA No translation available.
BC001324 mRNA Translation: AAH01324.1
BC006162 mRNA Translation: AAH06162.1
BC038402 mRNA Translation: AAH38402.1
AY211911 mRNA Translation: AAO65164.1 Frameshift.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS13308.1

NCBI Reference Sequences

More...RefSeqi		NP_079131.3, NM_024855.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000243903; ENSP00000243903; ENSG00000101442

Database of genes from NCBI RefSeq genomes

More...GeneIDi		79913

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:79913

UCSC genome browser

More...UCSCi		uc002xjd.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK022847 mRNA Translation: BAB14270.1
AL133519 Genomic DNA No translation available.
BC001324 mRNA Translation: AAH01324.1
BC006162 mRNA Translation: AAH06162.1
BC038402 mRNA Translation: AAH38402.1
AY211911 mRNA Translation: AAO65164.1 Frameshift.
CCDSiCCDS13308.1
RefSeqiNP_079131.3, NM_024855.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6HTSelectron microscopy4.80H1-607[»]
SMRiQ9H9F9
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi122993, 53 interactors
ComplexPortaliCPX-846, INO80 chromatin remodeling complex
CORUMiQ9H9F9
DIPiDIP-34297N
IntActiQ9H9F9, 49 interactors
MINTiQ9H9F9
STRINGi9606.ENSP00000243903

PTM databases

iPTMnetiQ9H9F9
PhosphoSitePlusiQ9H9F9

Genetic variation databases

BioMutaiACTR5
DMDMi110832751

Proteomic databases

EPDiQ9H9F9
jPOSTiQ9H9F9
MassIVEiQ9H9F9
MaxQBiQ9H9F9
PaxDbiQ9H9F9
PeptideAtlasiQ9H9F9
PRIDEiQ9H9F9
ProteomicsDBi81319

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		43543, 128 antibodies

Genome annotation databases

EnsembliENST00000243903; ENSP00000243903; ENSG00000101442
GeneIDi79913
KEGGihsa:79913
UCSCiuc002xjd.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79913
DisGeNETi79913

GeneCards: human genes, protein and diseases

More...GeneCardsi		ACTR5
HGNCiHGNC:14671, ACTR5
HPAiENSG00000101442, Low tissue specificity
neXtProtiNX_Q9H9F9
OpenTargetsiENSG00000101442
PharmGKBiPA24490
VEuPathDBiHostDB:ENSG00000101442.9

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0681, Eukaryota
GeneTreeiENSGT00720000108866
HOGENOMiCLU_008246_2_0_1
InParanoidiQ9H9F9
OMAiITNWNHQ
OrthoDBi344271at2759
PhylomeDBiQ9H9F9
TreeFamiTF324227

Enzyme and pathway databases

PathwayCommonsiQ9H9F9
ReactomeiR-HSA-5689603, UCH proteinases
R-HSA-5696394, DNA Damage Recognition in GG-NER
SignaLinkiQ9H9F9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		79913, 144 hits in 1006 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ACTR5, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		79913
PharosiQ9H9F9, Tbio

Protein Ontology

More...PROi		PR:Q9H9F9
RNActiQ9H9F9, protein

Gene expression databases

BgeeiENSG00000101442, Expressed in epithelium of mammary gland and 217 other tissues
GenevisibleiQ9H9F9, HS

Family and domain databases

InterProiView protein in InterPro
IPR004000, Actin
IPR004001, Actin_CS
IPR027664, Arp5
IPR043129, ATPase_NBD
PANTHERiPTHR11937, PTHR11937, 2 hits
PTHR11937:SF16, PTHR11937:SF16, 2 hits
PfamiView protein in Pfam
PF00022, Actin, 1 hit
SMARTiView protein in SMART
SM00268, ACTIN, 1 hit
SUPFAMiSSF53067, SSF53067, 2 hits
PROSITEiView protein in PROSITE
PS00432, ACTINS_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARP5_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H9F9
Secondary accession number(s): Q86WF7
, Q8IUY5, Q8N724, Q9BRN0, Q9BVB7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: July 25, 2006
Last modified: April 7, 2021
This is version 146 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. SIMILARITY comments
    Index of protein domains and families
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