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Entry version 138 (12 Aug 2020)
Sequence version 1 (01 Mar 2001)
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Protein

Damage-control phosphatase ARMT1

Gene

ARMT1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate (By similarity). Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism (By similarity). Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues (PubMed:25732820). Possibly methylates PCNA, suggesting it is involved in the DNA damage response (PubMed:25732820).By similarity1 Publication

Caution

Has been reportedly associated with a protein carboxyl methyltransferase activity, but whether this protein indeed has such an activity remains to be determined (PubMed:25732820). It has been later shown to belong to a family of metal-dependent phosphatases implicated in metabolite damage-control (PubMed:27322068).1 Publication1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mn2+By similarity, Ni2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi253Manganese or nickel; catalyticBy similarity1
Metal bindingi254Manganese or nickel; catalyticBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei258S-adenosyl-L-methionine1 Publication1
Metal bindingi291Manganese or nickel; catalyticBy similarity1
Binding sitei291S-adenosyl-L-methionine1 Publication1
Binding sitei404SubstrateBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Methyltransferase, Transferase
Biological processDNA damage
LigandManganese, Metal-binding, Nickel, S-adenosyl-L-methionine

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9H993

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Damage-control phosphatase ARMT1By similarity (EC:3.1.3.-By similarity)
Alternative name(s):
Acidic residue methyltransferase 11 Publication
Protein-glutamate O-methyltransferaseCurated (EC:2.1.1.-1 Publication)
Sugar phosphate phosphatase ARMT1By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ARMT11 PublicationImported
Synonyms:C6orf211Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000146476.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:17872, ARMT1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
616332, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H993

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
79624

Open Targets

More...
OpenTargetsi
ENSG00000146476

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134870747

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9H993, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ARMT1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74752737

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002307952 – 441Damage-control phosphatase ARMT1Add BLAST440

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineCombined sources1
Modified residuei40N6-acetyllysineCombined sources1
Modified residuei102PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Automethylated.1 Publication

Keywords - PTMi

Acetylation, Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q9H993

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q9H993

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q9H993

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H993

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H993

PeptideAtlas

More...
PeptideAtlasi
Q9H993

PRoteomics IDEntifications database

More...
PRIDEi
Q9H993

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
81298

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H993

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H993

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000146476, Expressed in female gonad and 239 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9H993, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H993, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000146476, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
122754, 33 interactors

Protein interaction database and analysis system

More...
IntActi
Q9H993, 14 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000356263

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9H993, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q9H993

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni253 – 254Substrate bindingBy similarity2
Regioni367 – 371Substrate bindingBy similarity5

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi401 – 404Subfamily III RTxK motifBy similarity4

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3870, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000064023

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_030117_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H993

KEGG Orthology (KO)

More...
KOi
K23114

Identification of Orthologs from Complete Genome Data

More...
OMAi
GFRPTNI

Database of Orthologous Groups

More...
OrthoDBi
856818at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H993

TreeFam database of animal gene trees

More...
TreeFami
TF314853

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036075, AF1104-like_sf
IPR039763, ARMT1
IPR002791, DUF89

The PANTHER Classification System

More...
PANTHERi
PTHR12260, PTHR12260, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01937, DUF89, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF111321, SSF111321, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9H993-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVVPASLSG QDVGSFAYLT IKDRIPQILT KVIDTLHRHK SEFFEKHGEE
60 70 80 90 100
GVEAEKKAIS LLSKLRNELQ TDKPFIPLVE KFVDTDIWNQ YLEYQQSLLN
110 120 130 140 150
ESDGKSRWFY SPWLLVECYM YRRIHEAIIQ SPPIDYFDVF KESKEQNFYG
160 170 180 190 200
SQESIIALCT HLQQLIRTIE DLDENQLKDE FFKLLQISLW GNKCDLSLSG
210 220 230 240 250
GESSSQNTNV LNSLEDLKPF ILLNDMEHLW SLLSNCKKTR EKASATRVYI
260 270 280 290 300
VLDNSGFELV TDLILADFLL SSELATEVHF YGKTIPWFVS DTTIHDFNWL
310 320 330 340 350
IEQVKHSNHK WMSKCGADWE EYIKMGKWVY HNHIFWTLPH EYCAMPQVAP
360 370 380 390 400
DLYAELQKAH LILFKGDLNY RKLTGDRKWE FSVPFHQALN GFHPAPLCTI
410 420 430 440
RTLKAEIQVG LQPGQGEQLL ASEPSWWTTG KYGIFQYDGP L
Length:441
Mass (Da):51,172
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3BE4D15528FDFC4E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5GZY1F5GZY1_HUMAN
Sugar phosphate phosphatase
ARMT1
322Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F2Z3I8F2Z3I8_HUMAN
Damage-control phosphatase ARMT1
ARMT1
56Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti120 – 121MY → ID in AAH11348 (PubMed:15489334).Curated2
Sequence conflicti148F → S in CAB53692 (PubMed:17974005).Curated1
Sequence conflicti173D → Y in AAH11348 (PubMed:15489334).Curated1
Sequence conflicti220F → Y in CAB53692 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05309073K → N. Corresponds to variant dbSNP:rs35036943Ensembl.1
Natural variantiVAR_02579177P → R1 PublicationCorresponds to variant dbSNP:rs17850732Ensembl.1
Natural variantiVAR_053091150G → E. Corresponds to variant dbSNP:rs35734927Ensembl.1
Natural variantiVAR_053092154S → A. Corresponds to variant dbSNP:rs34437617Ensembl.1
Natural variantiVAR_053093161H → P. Corresponds to variant dbSNP:rs36037706Ensembl.1
Natural variantiVAR_053094264I → V. Corresponds to variant dbSNP:rs35989216Ensembl.1
Natural variantiVAR_053095317A → T. Corresponds to variant dbSNP:rs35972078Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK022972 mRNA Translation: BAB14339.1
AL590543 Genomic DNA No translation available.
BC011348 mRNA Translation: AAH11348.1
AL110241 mRNA Translation: CAB53692.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5233.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T14772

NCBI Reference Sequences

More...
RefSeqi
NP_001273491.1, NM_001286562.1
NP_078849.1, NM_024573.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000367294; ENSP00000356263; ENSG00000146476

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79624

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79624

UCSC genome browser

More...
UCSCi
uc003qok.3, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK022972 mRNA Translation: BAB14339.1
AL590543 Genomic DNA No translation available.
BC011348 mRNA Translation: AAH11348.1
AL110241 mRNA Translation: CAB53692.2
CCDSiCCDS5233.1
PIRiT14772
RefSeqiNP_001273491.1, NM_001286562.1
NP_078849.1, NM_024573.2

3D structure databases

SMRiQ9H993
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi122754, 33 interactors
IntActiQ9H993, 14 interactors
STRINGi9606.ENSP00000356263

PTM databases

iPTMnetiQ9H993
PhosphoSitePlusiQ9H993

Polymorphism and mutation databases

BioMutaiARMT1
DMDMi74752737

Proteomic databases

EPDiQ9H993
jPOSTiQ9H993
MassIVEiQ9H993
MaxQBiQ9H993
PaxDbiQ9H993
PeptideAtlasiQ9H993
PRIDEiQ9H993
ProteomicsDBi81298

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1089, 146 antibodies

The DNASU plasmid repository

More...
DNASUi
79624

Genome annotation databases

EnsembliENST00000367294; ENSP00000356263; ENSG00000146476
GeneIDi79624
KEGGihsa:79624
UCSCiuc003qok.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79624
DisGeNETi79624
EuPathDBiHostDB:ENSG00000146476.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ARMT1
HGNCiHGNC:17872, ARMT1
HPAiENSG00000146476, Low tissue specificity
MIMi616332, gene
neXtProtiNX_Q9H993
OpenTargetsiENSG00000146476
PharmGKBiPA134870747

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3870, Eukaryota
GeneTreeiENSGT00530000064023
HOGENOMiCLU_030117_0_0_1
InParanoidiQ9H993
KOiK23114
OMAiGFRPTNI
OrthoDBi856818at2759
PhylomeDBiQ9H993
TreeFamiTF314853

Enzyme and pathway databases

PathwayCommonsiQ9H993

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
79624, 21 hits in 861 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ARMT1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
79624
PharosiQ9H993, Tbio

Protein Ontology

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PROi
PR:Q9H993
RNActiQ9H993, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000146476, Expressed in female gonad and 239 other tissues
ExpressionAtlasiQ9H993, baseline and differential
GenevisibleiQ9H993, HS

Family and domain databases

InterProiView protein in InterPro
IPR036075, AF1104-like_sf
IPR039763, ARMT1
IPR002791, DUF89
PANTHERiPTHR12260, PTHR12260, 1 hit
PfamiView protein in Pfam
PF01937, DUF89, 1 hit
SUPFAMiSSF111321, SSF111321, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARMT1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H993
Secondary accession number(s): Q96FC6, Q9UFY5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: March 1, 2001
Last modified: August 12, 2020
This is version 138 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. SIMILARITY comments
    Index of protein domains and families
  5. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  6. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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