SLC25A22

Functionⁱ

Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H⁺.1 Publication

GO - Molecular functionⁱ

amino acid:proton symporter activity Source: Reactome
high-affinity glutamate transmembrane transporter activity Source: GO_Central
L-glutamate transmembrane transporter activity
Source: UniProtKB
Inferred from direct assayⁱ
- 11897791

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

ion transport Source: Reactome
L-glutamate transmembrane transport
Source: UniProtKB
Inferred from direct assayⁱ
- 11897791
mitochondrial transport Source: GO_Central

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Symport, Transport

Biological process

Symport, Transport

Enzyme and pathway databases

Reactomeⁱ	R-HSA-428643 Organic anion transporters

Reactomeⁱ

R-HSA-428643 Organic anion transporters

Protein family/group databases

TCDBⁱ	2.A.29.14.3 the mitochondrial carrier (mc) family

TCDBⁱ

2.A.29.14.3 the mitochondrial carrier (mc) family

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Mitochondrial glutamate carrier 1 Short name: GC-1 Alternative name(s): Glutamate/H(+) symporter 1 Solute carrier family 25 member 22
Gene namesⁱ	Name:SLC25A22 Synonyms:GC1
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 11

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000177542.10
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:19954 SLC25A22
MIMⁱ	609302 gene
neXtProtⁱ	NX_Q9H936

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	12 – 32	Helical; Name=1Sequence analysisAdd BLAST	21
Transmembraneⁱ	62 – 82	Helical; Name=2Sequence analysisAdd BLAST	21
Transmembraneⁱ	107 – 127	Helical; Name=3Sequence analysisAdd BLAST	21
Transmembraneⁱ	189 – 209	Helical; Name=4Sequence analysisAdd BLAST	21
Transmembraneⁱ	223 – 243	Helical; Name=5Sequence analysisAdd BLAST	21
Transmembraneⁱ	292 – 312	Helical; Name=6Sequence analysisAdd BLAST	21

Keywords - Cellular componentⁱ

Membrane, Mitochondrion, Mitochondrion inner membrane

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Epileptic encephalopathy, early infantile, 3 (EIEE3)1 Publication

The disease is caused by mutations affecting the gene represented in this entry.

Disease descriptionA severe form of epilepsy characterized by frequent tonic seizures or spasms beginning in infancy with a specific EEG finding of suppression-burst patterns, characterized by high-voltage bursts alternating with almost flat suppression phases. Epileptic encephalopathy early infantile type 3 is characterized by a very early onset, erratic and fragmentary myoclonus, massive myoclonus, partial motor seizures and late tonic spasms. The prognosis is poor, with no effective treatment, and children with the condition either die within 1 to 2 years after birth or survive in a persistent vegetative state.

Keywords - Diseaseⁱ

Disease mutation, Epilepsy

Organism-specific databases

DisGeNET More...DisGeNETⁱ	79751
MalaCards human disease database More...MalaCardsⁱ	SLC25A22
MIMⁱ	609304 phenotype
Open Targets More...OpenTargetsⁱ	ENSG00000177542
Orphanetⁱ	1934 Early infantile epileptic encephalopathy 1935 Early myoclonic encephalopathy 293181 Malignant migrating partial seizures of infancy
PharmGKBⁱ	PA134955826

Chemistry databases

Drug and drug target database More...DrugBankⁱ	DB00142 L-Glutamic Acid

DrugBankⁱ

DB00142 L-Glutamic Acid

Polymorphism and mutation databases

BioMutaⁱ	SLC25A22
DMDMⁱ	34222632

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000090619	1 – 323	Mitochondrial glutamate carrier 1Add BLAST		323

Proteomic databases

EPDⁱ	Q9H936
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q9H936
PaxDbⁱ	Q9H936
PeptideAtlas More...PeptideAtlasⁱ	Q9H936
PRIDEⁱ	Q9H936
ProteomicsDBⁱ	81277
TopDownProteomicsⁱ	Q9H936

PTM databases

iPTMnetⁱ	Q9H936
PhosphoSitePlusⁱ	Q9H936
SwissPalmⁱ	Q9H936

Expressionⁱ

Tissue specificityⁱ

Highly expressed in most tissues.

Gene expression databases

Bgeeⁱ	ENSG00000177542 Expressed in 193 organ(s), highest expression level in cerebellar vermis
CleanExⁱ	HS_SLC25A22
ExpressionAtlasⁱ	Q9H936 baseline and differential
Genevisibleⁱ	Q9H936 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA014662

HPAⁱ

HPA014662

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	122862, 34 interactors
IntActⁱ	Q9H936, 36 interactors
Molecular INTeraction database More...MINTⁱ	Q9H936
STRINGⁱ	9606.ENSP00000322020

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9H936
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Repeatⁱ	6 – 93	Solcar 1Add BLAST	88
Repeatⁱ	101 – 214	Solcar 2Add BLAST	114
Repeatⁱ	223 – 312	Solcar 3Add BLAST	90

Sequence similaritiesⁱ

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]Curated

Keywords - Domainⁱ

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG0750 Eukaryota ENOG410Y240 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000062944
HOGENOMⁱ	HOG000168308
HOVERGENⁱ	HBG039469
InParanoidⁱ	Q9H936
KEGG Orthology (KO) More...KOⁱ	K15107
OMAⁱ	RKLMPET
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G08GT
PhylomeDBⁱ	Q9H936
TreeFamⁱ	TF313209

Family and domain databases

Gene3Dⁱ	1.50.40.10, 1 hit
InterProⁱ	View protein in InterPro IPR002067 Mit_carrier IPR018108 Mitochondrial_sb/sol_carrier IPR023395 Mt_carrier_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00153 Mito_carr, 3 hits
PRINTSⁱ	PR00926 MITOCARRIER
SUPFAMⁱ	SSF103506 SSF103506, 1 hit
PROSITEⁱ	View protein in PROSITE PS50920 SOLCAR, 3 hits

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 17 potential isoforms that are computationally mapped.Show all Align All

Q9H936-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MADKQISLPA KLINGGIAGL IGVTCVFPID LAKTRLQNQQ NGQRVYTSMS 
        60         70         80         90        100
DCLIKTVRSE GYFGMYRGAA VNLTLVTPEK AIKLAANDFF RHQLSKDGQK 
       110        120        130        140        150
LTLLKEMLAG CGAGTCQVIV TTPMEMLKIQ LQDAGRIAAQ RKILAAQGQL 
       160        170        180        190        200
SAQGGAQPSV EAPAAPRPTA TQLTRDLLRS RGIAGLYKGL GATLLRDVPF 
       210        220        230        240        250
SVVYFPLFAN LNQLGRPASE EKSPFYVSFL AGCVAGSAAA VAVNPCDVVK 
       260        270        280        290        300
TRLQSLQRGV NEDTYSGILD CARKILRHEG PSAFLKGAYC RALVIAPLFG 
       310        320 
IAQVVYFLGI AESLLGLLQD PQA

Length:323

Mass (Da):34,470

Last modified:March 1, 2001 - v1

Checksum:ⁱD0E06FD88E5A3198

GO

Computationally mapped potential isoform sequencesⁱ

There are 17 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name	Protein names	Gene names	Length	Annotation

	E9PI74	E9PI74_HUMAN	Mitochondrial glutamate carrier 1 Mitochondrial glutamate carrier 1	SLC25A22	127	Annotation score:
	K4DIB6	K4DIB6_HUMAN	Mitochondrial glutamate carrier 1 Mitochondrial glutamate carrier 1	SLC25A22	156	Annotation score:
	E9PS95	E9PS95_HUMAN	Mitochondrial glutamate carrier 1 Mitochondrial glutamate carrier 1	SLC25A22	196	Annotation score:
	K4DIB0	K4DIB0_HUMAN	Mitochondrial glutamate carrier 1 Mitochondrial glutamate carrier 1	SLC25A22	103	Annotation score:
	K4DIA8	K4DIA8_HUMAN	Mitochondrial glutamate carrier 1 Mitochondrial glutamate carrier 1	SLC25A22	190	Annotation score:
	K4DIB8	K4DIB8_HUMAN	Mitochondrial glutamate carrier 1 Mitochondrial glutamate carrier 1	SLC25A22	177	Annotation score:
	E9PQ36	E9PQ36_HUMAN	Mitochondrial glutamate carrier 1 Mitochondrial glutamate carrier 1	SLC25A22	134	Annotation score:
	K4DIB3	K4DIB3_HUMAN	Mitochondrial glutamate carrier 1 Mitochondrial glutamate carrier 1	SLC25A22	161	Annotation score:
	K4DIA2	K4DIA2_HUMAN	Mitochondrial glutamate carrier 1 Mitochondrial glutamate carrier 1	SLC25A22	114	Annotation score:
	E9PJH7	E9PJH7_HUMAN	Mitochondrial glutamate carrier 1 Mitochondrial glutamate carrier 1	SLC25A22	313	Annotation score:
There are more potential isoformsShow all

Sequence cautionⁱ

The sequence AAH24212 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_022737	206	P → L in EIEE3. 1 PublicationCorresponds to variant dbSNP:rs121918334EnsemblClinVar.		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AJ428202 mRNA Translation: CAD21007.1 AK023106 mRNA Translation: BAB14407.1 AK290481 mRNA Translation: BAF83170.1 AP006621 Genomic DNA No translation available. BC019033 mRNA Translation: AAH19033.1 BC023545 mRNA Translation: AAH23545.1 BC024212 mRNA Translation: AAH24212.2 Different initiation.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS7715.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001177989.1, NM_001191060.1 NP_001177990.1, NM_001191061.1 NP_078974.1, NM_024698.5 XP_011518671.1, XM_011520369.1 XP_011518672.1, XM_011520370.1 XP_011518673.1, XM_011520371.1
UniGeneⁱ	Hs.99486

Genome annotation databases

Ensemblⁱ	ENST00000320230; ENSP00000322020; ENSG00000177542 ENST00000531214; ENSP00000437236; ENSG00000177542 ENST00000628067; ENSP00000486058; ENSG00000177542
GeneIDⁱ	79751
KEGGⁱ	hsa:79751
UCSC genome browser More...UCSCⁱ	uc001lri.3 human

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9H936	Mitochondrial glutamate carrier 1 (Fragment)		HUMAN		197	UniRef100_Q9H936
SLC25A22 isoform 13 (Fragment)		PANTR		97
Mitochondrial glutamate carrier 1 (Fragment)		HUMAN		97
Mitochondrial glutamate carrier 1 (Fragment)		HUMAN		247
Mitochondrial glutamate carrier 1 (Fragment)		HUMAN		127
+16

Protein	Similar proteins		Species	Score	Length	Source
Q9H936	Mitochondrial glutamate carrier 1		MOUSE		323	UniRef90_Q9H936
Mitochondrial glutamate carrier 1		PONAB		323
Mitochondrial glutamate carrier 1 (Fragment)		HUMAN		197
SLC25A22 isoform 13 (Fragment)		PANTR		97
mitochondrial glutamate carrier 1		NEOSC		323
+110

Protein	Similar proteins		Species	Score	Length	Source
Q9H936	Mitochondrial glutamate carrier 1		PONAB		323	UniRef50_Q9H936
Mitochondrial glutamate carrier 1		MOUSE		323
Mitochondrial glutamate carrier 1 (Fragment)		HUMAN		197
SLC25A22 isoform 13 (Fragment)		PANTR		97
mitochondrial glutamate carrier 1		ERIEU		323
+231

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AJ428202 mRNA Translation: CAD21007.1 AK023106 mRNA Translation: BAB14407.1 AK290481 mRNA Translation: BAF83170.1 AP006621 Genomic DNA No translation available. BC019033 mRNA Translation: AAH19033.1 BC023545 mRNA Translation: AAH23545.1 BC024212 mRNA Translation: AAH24212.2 Different initiation.
CCDSⁱ	CCDS7715.1
RefSeqⁱ	NP_001177989.1, NM_001191060.1 NP_001177990.1, NM_001191061.1 NP_078974.1, NM_024698.5 XP_011518671.1, XM_011520369.1 XP_011518672.1, XM_011520370.1 XP_011518673.1, XM_011520371.1
UniGeneⁱ	Hs.99486

3D structure databases

ProteinModelPortalⁱ	Q9H936
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	122862, 34 interactors
IntActⁱ	Q9H936, 36 interactors
MINTⁱ	Q9H936
STRINGⁱ	9606.ENSP00000322020

Chemistry databases

DrugBankⁱ	DB00142 L-Glutamic Acid

DrugBankⁱ

DB00142 L-Glutamic Acid

Protein family/group databases

TCDBⁱ	2.A.29.14.3 the mitochondrial carrier (mc) family

TCDBⁱ

2.A.29.14.3 the mitochondrial carrier (mc) family

PTM databases

iPTMnetⁱ	Q9H936
PhosphoSitePlusⁱ	Q9H936
SwissPalmⁱ	Q9H936

Polymorphism and mutation databases

BioMutaⁱ	SLC25A22
DMDMⁱ	34222632

Proteomic databases

EPDⁱ	Q9H936
MaxQBⁱ	Q9H936
PaxDbⁱ	Q9H936
PeptideAtlasⁱ	Q9H936
PRIDEⁱ	Q9H936
ProteomicsDBⁱ	81277
TopDownProteomicsⁱ	Q9H936

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	79751
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000320230; ENSP00000322020; ENSG00000177542 ENST00000531214; ENSP00000437236; ENSG00000177542 ENST00000628067; ENSP00000486058; ENSG00000177542
GeneIDⁱ	79751
KEGGⁱ	hsa:79751
UCSCⁱ	uc001lri.3 human

Organism-specific databases

CTDⁱ	79751
DisGeNETⁱ	79751
EuPathDBⁱ	HostDB:ENSG00000177542.10
GeneCardsⁱ	SLC25A22
HGNCⁱ	HGNC:19954 SLC25A22
HPAⁱ	HPA014662
MalaCardsⁱ	SLC25A22
MIMⁱ	609302 gene 609304 phenotype
neXtProtⁱ	NX_Q9H936
OpenTargetsⁱ	ENSG00000177542
Orphanetⁱ	1934 Early infantile epileptic encephalopathy 1935 Early myoclonic encephalopathy 293181 Malignant migrating partial seizures of infancy
PharmGKBⁱ	PA134955826
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0750 Eukaryota ENOG410Y240 LUCA
GeneTreeⁱ	ENSGT00530000062944
HOGENOMⁱ	HOG000168308
HOVERGENⁱ	HBG039469
InParanoidⁱ	Q9H936
KOⁱ	K15107
OMAⁱ	RKLMPET
OrthoDBⁱ	EOG091G08GT
PhylomeDBⁱ	Q9H936
TreeFamⁱ	TF313209

Enzyme and pathway databases

Reactomeⁱ	R-HSA-428643 Organic anion transporters

Reactomeⁱ

R-HSA-428643 Organic anion transporters

Miscellaneous databases

GenomeRNAiⁱ	79751
Protein Ontology More...PROⁱ	PR:Q9H936
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000177542 Expressed in 193 organ(s), highest expression level in cerebellar vermis
CleanExⁱ	HS_SLC25A22
ExpressionAtlasⁱ	Q9H936 baseline and differential
Genevisibleⁱ	Q9H936 HS

Family and domain databases

Gene3Dⁱ	1.50.40.10, 1 hit
InterProⁱ	View protein in InterPro IPR002067 Mit_carrier IPR018108 Mitochondrial_sb/sol_carrier IPR023395 Mt_carrier_dom_sf
Pfamⁱ	View protein in Pfam PF00153 Mito_carr, 3 hits
PRINTSⁱ	PR00926 MITOCARRIER
SUPFAMⁱ	SSF103506 SSF103506, 1 hit
PROSITEⁱ	View protein in PROSITE PS50920 SOLCAR, 3 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	GHC1_HUMAN
Accessionⁱ	Q9H936Primary (citable) accession number: Q9H936 Secondary accession number(s): A8K366 Q8TBU8
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	August 22, 2003
	Last sequence update:	March 1, 2001
	Last modified:	October 10, 2018
	This is version 158 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
SIMILARITY comments
Index of protein domains and families
Human chromosome 11
Human chromosome 11: entries, gene names and cross-references to MIM
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

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UniParc

Help

UniRef

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Supporting data

UniProtKB - Q9H936 (GHC1_HUMAN)

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Mitochondrial glutamate carrier 1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Mitochondrion

Mitochondrion

Other locations

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Natural variant

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

Keywords - Diseaseⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ