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Protein

Ubiquitin carboxyl-terminal hydrolase MINDY-3

Gene

MINDY3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.1 Publication

Caution

Was named CARP for 'CARD domain-containing protein' by PubMed:12054670. However, no CARD domain is detected by any prediction tool.Curated

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei51NucleophileBy similarity1
Active sitei287Proton acceptorBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protease, Thiol protease
Biological processApoptosis, Ubl conjugation pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ubiquitin carboxyl-terminal hydrolase MINDY-3 (EC:3.4.19.12)
Alternative name(s):
Dermal papilla-derived protein 5
Deubiquitinating enzyme MINDY-3
Protein CARP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MINDY3Imported
Synonyms:C10orf97, CARP, DERP5, FAM188A
ORF Names:MSTP126, My042
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000148481.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23578 MINDY3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611649 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H8M7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
80013

Open Targets

More...
OpenTargetsi
ENSG00000148481

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA165548562

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM188A

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74761533

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003175601 – 445Ubiquitin carboxyl-terminal hydrolase MINDY-3Add BLAST445

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei125PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H8M7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H8M7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H8M7

PeptideAtlas

More...
PeptideAtlasi
Q9H8M7

PRoteomics IDEntifications database

More...
PRIDEi
Q9H8M7

ProteomicsDB human proteome resource

More...
ProteomicsDBi
81227
81228 [Q9H8M7-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H8M7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H8M7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed with high levels in heart, skeletal muscle, and kidney, and low levels in liver and brain (PubMed:12054670). Also expressed in lung (at protein level) (PubMed:21499297).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000148481 Expressed in 215 organ(s), highest expression level in corpus callosum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9H8M7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H8M7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA038400
HPA038406

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with COPS5.1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123069, 32 interactors

Protein interaction database and analysis system

More...
IntActi
Q9H8M7, 12 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000277632

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9H8M7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2871 Eukaryota
ENOG410XSGV LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155958

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG061682

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H8M7

KEGG Orthology (KO)

More...
KOi
K22647

Identification of Orthologs from Complete Genome Data

More...
OMAi
LVSEPEY

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0TF1

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H8M7

TreeFam database of animal gene trees

More...
TreeFami
TF323996

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025257 DUF4205
IPR011992 EF-hand-dom_pair
IPR039785 MINY3/4

The PANTHER Classification System

More...
PANTHERi
PTHR12473 PTHR12473, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13898 DUF4205, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01174 DUF4205, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47473 SSF47473, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H8M7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSELTKELME LVWGTKSSPG LSDTIFCRWT QGFVFSESEG SALEQFEGGP
60 70 80 90 100
CAVIAPVQAF LLKKLLFSSE KSSWRDCSEE EQKELLCHTL CDILESACCD
110 120 130 140 150
HSGSYCLVSW LRGKTTEETA SISGSPAESS CQVEHSSALA VEELGFERFH
160 170 180 190 200
ALIQKRSFRS LPELKDAVLD QYSMWGNKFG VLLFLYSVLL TKGIENIKNE
210 220 230 240 250
IEDASEPLID PVYGHGSQSL INLLLTGHAV SNVWDGDREC SGMKLLGIHE
260 270 280 290 300
QAAVGFLTLM EALRYCKVGS YLKSPKFPIW IVGSETHLTV FFAKDMALVA
310 320 330 340 350
PEAPSEQARR VFQTYDPEDN GFIPDSLLED VMKALDLVSD PEYINLMKNK
360 370 380 390 400
LDPEGLGIIL LGPFLQEFFP DQGSSGPESF TVYHYNGLKQ SNYNEKVMYV
410 420 430 440
EGTAVVMGFE DPMLQTDDTP IKRCLQTKWP YIELLWTTDR SPSLN
Length:445
Mass (Da):49,725
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF30B4A5E357AF52E
GO
Isoform 2 (identifier: Q9H8M7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     137-445: Missing.

Show »
Length:136
Mass (Da):14,942
Checksum:iFB29CAFB7F8C68AB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
X6RC97X6RC97_HUMAN
Ubiquitin carboxyl-terminal hydrola...
MINDY3
164Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
X6R9S5X6R9S5_HUMAN
Ubiquitin carboxyl-terminal hydrola...
MINDY3
150Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
X6RC30X6RC30_HUMAN
Ubiquitin carboxyl-terminal hydrola...
MINDY3
182Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAG43159 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH61585 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAQ13660 differs from that shown. Reason: Frameshift at position 111.Curated
The sequence EAW86233 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti31Q → R in CAG33596 (Ref. 5) Curated1
Sequence conflicti96S → G in AAH20605 (PubMed:15489334).Curated1
Sequence conflicti111L → V in AAQ13660 (Ref. 6) Curated1
Sequence conflicti116T → A in CAG33596 (Ref. 5) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_031039137 – 445Missing in isoform 2. 2 PublicationsAdd BLAST309

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB014761 mRNA Translation: BAB87802.1
AK023459 mRNA Translation: BAB14582.1
AL833873 mRNA Translation: CAD38730.1
CR457315 mRNA Translation: CAG33596.1
AF176916 mRNA Translation: AAQ13660.1 Frameshift.
AL590439 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86233.1 Sequence problems.
CH471072 Genomic DNA Translation: EAW86234.1
BC020605 mRNA Translation: AAH20605.1
BC061585 mRNA Translation: AAH61585.1 Sequence problems.
BC067799 mRNA Translation: AAH67799.1
AF063600 mRNA Translation: AAG43159.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS7110.1 [Q9H8M7-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
JC7861

NCBI Reference Sequences

More...
RefSeqi
NP_001305259.1, NM_001318330.1
NP_079224.1, NM_024948.3 [Q9H8M7-1]
XP_005252657.1, XM_005252600.2
XP_005252659.1, XM_005252602.2
XP_011517996.1, XM_011519694.1
XP_016872162.1, XM_017016673.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.158870

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000277632; ENSP00000277632; ENSG00000148481 [Q9H8M7-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80013

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:80013

UCSC genome browser

More...
UCSCi
uc001iod.2 human [Q9H8M7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB014761 mRNA Translation: BAB87802.1
AK023459 mRNA Translation: BAB14582.1
AL833873 mRNA Translation: CAD38730.1
CR457315 mRNA Translation: CAG33596.1
AF176916 mRNA Translation: AAQ13660.1 Frameshift.
AL590439 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86233.1 Sequence problems.
CH471072 Genomic DNA Translation: EAW86234.1
BC020605 mRNA Translation: AAH20605.1
BC061585 mRNA Translation: AAH61585.1 Sequence problems.
BC067799 mRNA Translation: AAH67799.1
AF063600 mRNA Translation: AAG43159.1 Different initiation.
CCDSiCCDS7110.1 [Q9H8M7-1]
PIRiJC7861
RefSeqiNP_001305259.1, NM_001318330.1
NP_079224.1, NM_024948.3 [Q9H8M7-1]
XP_005252657.1, XM_005252600.2
XP_005252659.1, XM_005252602.2
XP_011517996.1, XM_011519694.1
XP_016872162.1, XM_017016673.1
UniGeneiHs.158870

3D structure databases

ProteinModelPortaliQ9H8M7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123069, 32 interactors
IntActiQ9H8M7, 12 interactors
STRINGi9606.ENSP00000277632

PTM databases

iPTMnetiQ9H8M7
PhosphoSitePlusiQ9H8M7

Polymorphism and mutation databases

BioMutaiFAM188A
DMDMi74761533

Proteomic databases

EPDiQ9H8M7
MaxQBiQ9H8M7
PaxDbiQ9H8M7
PeptideAtlasiQ9H8M7
PRIDEiQ9H8M7
ProteomicsDBi81227
81228 [Q9H8M7-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
80013
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000277632; ENSP00000277632; ENSG00000148481 [Q9H8M7-1]
GeneIDi80013
KEGGihsa:80013
UCSCiuc001iod.2 human [Q9H8M7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80013
DisGeNETi80013
EuPathDBiHostDB:ENSG00000148481.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MINDY3
HGNCiHGNC:23578 MINDY3
HPAiHPA038400
HPA038406
MIMi611649 gene
neXtProtiNX_Q9H8M7
OpenTargetsiENSG00000148481
PharmGKBiPA165548562

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG2871 Eukaryota
ENOG410XSGV LUCA
GeneTreeiENSGT00940000155958
HOVERGENiHBG061682
InParanoidiQ9H8M7
KOiK22647
OMAiLVSEPEY
OrthoDBiEOG091G0TF1
PhylomeDBiQ9H8M7
TreeFamiTF323996

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
FAM188A human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
80013

Protein Ontology

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PROi
PR:Q9H8M7

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000148481 Expressed in 215 organ(s), highest expression level in corpus callosum
ExpressionAtlasiQ9H8M7 baseline and differential
GenevisibleiQ9H8M7 HS

Family and domain databases

InterProiView protein in InterPro
IPR025257 DUF4205
IPR011992 EF-hand-dom_pair
IPR039785 MINY3/4
PANTHERiPTHR12473 PTHR12473, 1 hit
PfamiView protein in Pfam
PF13898 DUF4205, 1 hit
SMARTiView protein in SMART
SM01174 DUF4205, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMINY3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H8M7
Secondary accession number(s): Q5SZ68
, Q5SZ69, Q5SZ70, Q6IA40, Q6P7P0, Q7Z2S1, Q8WUF1, Q9H3I4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: March 1, 2001
Last modified: December 5, 2018
This is version 149 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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