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Entry version 122 (11 Dec 2019)
Sequence version 1 (01 Mar 2001)
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Protein

MANSC domain-containing protein 1

Gene

MANSC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
MANSC domain-containing protein 1
Alternative name(s):
Loss of heterozygosity 12 chromosomal region 3 protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MANSC1
Synonyms:LOH12CR3
ORF Names:UNQ316/PRO361
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000111261.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25505 MANSC1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H8J5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini27 – 385ExtracellularSequence analysisAdd BLAST359
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei386 – 408HelicalSequence analysisAdd BLAST23
Topological domaini409 – 431CytoplasmicSequence analysisAdd BLAST23

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
54682

Open Targets

More...
OpenTargetsi
ENSG00000111261

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134948173

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9H8J5 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MANSC1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
48428493

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 26Sequence analysisAdd BLAST26
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002163627 – 431MANSC domain-containing protein 1Add BLAST405

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi72N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi222N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi251N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi327N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi352N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H8J5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H8J5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9H8J5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H8J5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H8J5

PeptideAtlas

More...
PeptideAtlasi
Q9H8J5

PRoteomics IDEntifications database

More...
PRIDEi
Q9H8J5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
81214 [Q9H8J5-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H8J5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H8J5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000111261 Expressed in 224 organ(s), highest expression level in saliva-secreting gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9H8J5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H8J5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA007955
HPA007956

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
120101, 98 interactors

Protein interaction database and analysis system

More...
IntActi
Q9H8J5, 90 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000438205

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9H8J5 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini33 – 117MANSCPROSITE-ProRule annotationAdd BLAST85

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi237 – 332Thr-richAdd BLAST96

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IT12 Eukaryota
ENOG4112D4M LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153377

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000113476

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H8J5

Identification of Orthologs from Complete Genome Data

More...
OMAi
SQNCPTK

Database of Orthologous Groups

More...
OrthoDBi
778983at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H8J5

TreeFam database of animal gene trees

More...
TreeFami
TF336966

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013980 MANSC_dom
IPR011106 MANSC_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07502 MANEC, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00765 MANEC, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50986 MANSC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H8J5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFFGGEGSLT YTLVIICFLT LRLSASQNCL KKSLEDVVID IQSSLSKGIR
60 70 80 90 100
GNEPVYTSTQ EDCINSCCST KNISGDKACN LMIFDTRKTA RQPNCYLFFC
110 120 130 140 150
PNEEACPLKP AKGLMSYRII TDFPSLTRNL PSQELPQEDS LLHGQFSQAV
160 170 180 190 200
TPLAHHHTDY SKPTDISWRD TLSQKFGSSD HLEKLFKMDE ASAQLLAYKE
210 220 230 240 250
KGHSQSSQFS SDQEIAHLLP ENVSALPATV AVASPHTTSA TPKPATLLPT
260 270 280 290 300
NASVTPSGTS QPQLATTAPP VTTVTSQPPT TLISTVFTRA AATLQAMATT
310 320 330 340 350
AVLTTTFQAP TDSKGSLETI PFTEISNLTL NTGNVYNPTA LSMSNVESST
360 370 380 390 400
MNKTASWEGR EASPGSSSQG SVPENQYGLP FEKWLLIGSL LFGVLFLVIG
410 420 430
LVLLGRILSE SLRRKRYSRL DYLINGIYVD I
Length:431
Mass (Da):46,810
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i189136416F0F89AE
GO
Isoform 2 (identifier: Q9H8J5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     14-47: Missing.

Show »
Length:397
Mass (Da):43,063
Checksum:iE2FEFF2E61122C62
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5H3M3F5H3M3_HUMAN
MANSC domain-containing protein 1
MANSC1
350Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H6G8F5H6G8_HUMAN
MANSC domain-containing protein 1
MANSC1
57Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02184055V → I1 PublicationCorresponds to variant dbSNP:rs3741798Ensembl.1
Natural variantiVAR_061682141L → V. Corresponds to variant dbSNP:rs34668262Ensembl.1
Natural variantiVAR_051151165D → N. Corresponds to variant dbSNP:rs17375215Ensembl.1
Natural variantiVAR_021841375N → Y. Corresponds to variant dbSNP:rs3741803Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_05592714 – 47Missing in isoform 2. 1 PublicationAdd BLAST34

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY358563 mRNA Translation: AAQ88926.1
AK001160 mRNA Translation: BAA91526.1
AK023622 mRNA Translation: BAB14621.1
AC007621 Genomic DNA No translation available.
CH471094 Genomic DNA Translation: EAW96254.1
BC032998 mRNA Translation: AAH32998.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS86284.1 [Q9H8J5-2]
CCDS8648.1 [Q9H8J5-1]

NCBI Reference Sequences

More...
RefSeqi
NP_060520.2, NM_018050.2 [Q9H8J5-1]
XP_016875020.1, XM_017019531.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000396349; ENSP00000379638; ENSG00000111261 [Q9H8J5-2]
ENST00000535902; ENSP00000438205; ENSG00000111261 [Q9H8J5-1]
ENST00000626912; ENSP00000487244; ENSG00000281818 [Q9H8J5-2]
ENST00000629245; ENSP00000487587; ENSG00000281818 [Q9H8J5-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
54682

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:54682

UCSC genome browser

More...
UCSCi
uc001rai.2 human [Q9H8J5-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358563 mRNA Translation: AAQ88926.1
AK001160 mRNA Translation: BAA91526.1
AK023622 mRNA Translation: BAB14621.1
AC007621 Genomic DNA No translation available.
CH471094 Genomic DNA Translation: EAW96254.1
BC032998 mRNA Translation: AAH32998.1
CCDSiCCDS86284.1 [Q9H8J5-2]
CCDS8648.1 [Q9H8J5-1]
RefSeqiNP_060520.2, NM_018050.2 [Q9H8J5-1]
XP_016875020.1, XM_017019531.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi120101, 98 interactors
IntActiQ9H8J5, 90 interactors
STRINGi9606.ENSP00000438205

PTM databases

iPTMnetiQ9H8J5
PhosphoSitePlusiQ9H8J5

Polymorphism and mutation databases

BioMutaiMANSC1
DMDMi48428493

Proteomic databases

EPDiQ9H8J5
jPOSTiQ9H8J5
MassIVEiQ9H8J5
MaxQBiQ9H8J5
PaxDbiQ9H8J5
PeptideAtlasiQ9H8J5
PRIDEiQ9H8J5
ProteomicsDBi81214 [Q9H8J5-1]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
54682

Genome annotation databases

EnsembliENST00000396349; ENSP00000379638; ENSG00000111261 [Q9H8J5-2]
ENST00000535902; ENSP00000438205; ENSG00000111261 [Q9H8J5-1]
ENST00000626912; ENSP00000487244; ENSG00000281818 [Q9H8J5-2]
ENST00000629245; ENSP00000487587; ENSG00000281818 [Q9H8J5-1]
GeneIDi54682
KEGGihsa:54682
UCSCiuc001rai.2 human [Q9H8J5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54682
DisGeNETi54682
EuPathDBiHostDB:ENSG00000111261.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MANSC1
HGNCiHGNC:25505 MANSC1
HPAiHPA007955
HPA007956
neXtProtiNX_Q9H8J5
OpenTargetsiENSG00000111261
PharmGKBiPA134948173

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IT12 Eukaryota
ENOG4112D4M LUCA
GeneTreeiENSGT00940000153377
HOGENOMiHOG000113476
InParanoidiQ9H8J5
OMAiSQNCPTK
OrthoDBi778983at2759
PhylomeDBiQ9H8J5
TreeFamiTF336966

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MANSC1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
54682
PharosiQ9H8J5 Tdark

Protein Ontology

More...
PROi
PR:Q9H8J5
RNActiQ9H8J5 protein

Gene expression databases

BgeeiENSG00000111261 Expressed in 224 organ(s), highest expression level in saliva-secreting gland
ExpressionAtlasiQ9H8J5 baseline and differential
GenevisibleiQ9H8J5 HS

Family and domain databases

InterProiView protein in InterPro
IPR013980 MANSC_dom
IPR011106 MANSC_N
PfamiView protein in Pfam
PF07502 MANEC, 1 hit
SMARTiView protein in SMART
SM00765 MANEC, 1 hit
PROSITEiView protein in PROSITE
PS50986 MANSC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMANS1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H8J5
Secondary accession number(s): Q8NEC1, Q9NW60
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: March 1, 2001
Last modified: December 11, 2019
This is version 122 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
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