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UniProtKB - Q9H8H3 (MET7A_HUMAN)

Entry version 160 (23 Feb 2022)
Sequence version 1 (01 Mar 2001)
Previous versions | rss
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Protein

Putative methyltransferase-like protein 7A

Gene

METTL7A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Putative methyltransferase.

Curated

(Microbial infection) May be involved in the assembly and release stages of hepatitis C virus (HCV) life cycle and thus play a crucial role in HCV propagation.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processHost-virus interaction

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9H8H3

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-6798695, Neutrophil degranulation

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9H8H3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative methyltransferase-like protein 7ACurated (EC:2.1.1.-Curated)
Alternative name(s):
Protein AAM-B1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:METTL7A
ORF Names:PRO0066, UNQ1902/PRO4348
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:24550, METTL7A

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		618338, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9H8H3

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000185432

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Endoplasmic reticulum, Lipid droplet, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		25840

Open Targets

More...OpenTargetsi		ENSG00000185432

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA128394635

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9H8H3, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		METTL7A

Domain mapping of disease mutations (DMDM)

More...DMDMi		74761529

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 29Sequence analysisAdd BLAST29
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000025192130 – 244Putative methyltransferase-like protein 7AAdd BLAST215

Proteomic databases

The CPTAC Assay portal

More...CPTACi		CPTAC-238
CPTAC-239

Encyclopedia of Proteome Dynamics

More...EPDi		Q9H8H3

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9H8H3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9H8H3

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9H8H3

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9H8H3

PeptideAtlas

More...PeptideAtlasi		Q9H8H3

PRoteomics IDEntifications database

More...PRIDEi		Q9H8H3

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		81213

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9H8H3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9H8H3

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q9H8H3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000185432, Expressed in substantia nigra and 250 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9H8H3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9H8H3, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000185432, Tissue enhanced (liver)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

(Microbial infection) Interacts with HCV non-structural protein 4B/NS4B (via C-terminal region); this interaction may promote the recruitment of NS4B in the proximity of lipid droplet.

1 Publication

Self-associates.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		117366, 357 interactors

Protein interaction database and analysis system

More...IntActi		Q9H8H3, 19 interactors

Molecular INTeraction database

More...MINTi		Q9H8H3

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000448785

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9H8H3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9H8H3

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 28Targeting to lipid droplets1 PublicationAdd BLAST28

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the methyltransferase superfamily.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4300, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000154786

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9H8H3

Identification of Orthologs from Complete Genome Data

More...OMAi		ETWKYVE

Database of Orthologous Groups

More...OrthoDBi		1178802at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9H8H3

TreeFam database of animal gene trees

More...TreeFami		TF331790

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013216, Methyltransf_11
IPR029063, SAM-dependent_MTases

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08241, Methyltransf_11, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53335, SSF53335, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9H8H3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MELTIFILRL AIYILTFPLY LLNFLGLWSW ICKKWFPYFL VRFTVIYNEQ 
        60         70         80         90        100
MASKKRELFS NLQEFAGPSG KLSLLEVGCG TGANFKFYPP GCRVTCIDPN 
       110        120        130        140        150
PNFEKFLIKS IAENRHLQFE RFVVAAGENM HQVADGSVDV VVCTLVLCSV 
       160        170        180        190        200
KNQERILREV CRVLRPGGAF YFMEHVAAEC STWNYFWQQV LDPAWHLLFD 
       210        220        230        240 
GCNLTRESWK ALERASFSKL KLQHIQAPLS WELVRPHIYG YAVK
Length:244
Mass (Da):28,319
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6967783BAB2348BE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8VQX6F8VQX6_HUMAN
Methyltransferase-like protein 7A
METTL7A
180Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YI09H0YI09_HUMAN
Methyltransferase-like protein 7A
METTL7A
244Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF20268 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti39F → L in BAB14913 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_050296134A → T. Corresponds to variant dbSNP:rs28372674Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AJ536233 mRNA Translation: CAD60207.1
AY358797 mRNA Translation: AAQ89157.1
AK023693 mRNA Translation: BAB14643.1
AK024409 mRNA Translation: BAB14913.1
BC004492 mRNA Translation: AAH04492.1
BC008180 mRNA Translation: AAH08180.1
AL050159 mRNA Translation: CAB43300.1
AF113007 mRNA Translation: AAF20268.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS8804.1

Protein sequence database of the Protein Information Resource

More...PIRi		T08785

NCBI Reference Sequences

More...RefSeqi		NP_054752.3, NM_014033.3
XP_006719395.1, XM_006719332.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000332160; ENSP00000331787; ENSG00000185432
ENST00000547104; ENSP00000447542; ENSG00000185432
ENST00000548553; ENSP00000448785; ENSG00000185432

Database of genes from NCBI RefSeq genomes

More...GeneIDi		25840

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:25840

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000332160.5; ENSP00000331787.4; NM_014033.4; NP_054752.3

UCSC genome browser

More...UCSCi		uc001rxb.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ536233 mRNA Translation: CAD60207.1
AY358797 mRNA Translation: AAQ89157.1
AK023693 mRNA Translation: BAB14643.1
AK024409 mRNA Translation: BAB14913.1
BC004492 mRNA Translation: AAH04492.1
BC008180 mRNA Translation: AAH08180.1
AL050159 mRNA Translation: CAB43300.1
AF113007 mRNA Translation: AAF20268.1 Different initiation.
CCDSiCCDS8804.1
PIRiT08785
RefSeqiNP_054752.3, NM_014033.3
XP_006719395.1, XM_006719332.1

3D structure databases

SMRiQ9H8H3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi117366, 357 interactors
IntActiQ9H8H3, 19 interactors
MINTiQ9H8H3
STRINGi9606.ENSP00000448785

PTM databases

iPTMnetiQ9H8H3
PhosphoSitePlusiQ9H8H3
SwissPalmiQ9H8H3

Genetic variation databases

BioMutaiMETTL7A
DMDMi74761529

Proteomic databases

CPTACiCPTAC-238
CPTAC-239
EPDiQ9H8H3
jPOSTiQ9H8H3
MassIVEiQ9H8H3
MaxQBiQ9H8H3
PaxDbiQ9H8H3
PeptideAtlasiQ9H8H3
PRIDEiQ9H8H3
ProteomicsDBi81213

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		2699, 235 antibodies from 26 providers

The DNASU plasmid repository

More...DNASUi		25840

Genome annotation databases

EnsembliENST00000332160; ENSP00000331787; ENSG00000185432
ENST00000547104; ENSP00000447542; ENSG00000185432
ENST00000548553; ENSP00000448785; ENSG00000185432
GeneIDi25840
KEGGihsa:25840
MANE-SelectiENST00000332160.5; ENSP00000331787.4; NM_014033.4; NP_054752.3
UCSCiuc001rxb.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		25840
DisGeNETi25840

GeneCards: human genes, protein and diseases

More...GeneCardsi		METTL7A
HGNCiHGNC:24550, METTL7A
HPAiENSG00000185432, Tissue enhanced (liver)
MIMi618338, gene
neXtProtiNX_Q9H8H3
OpenTargetsiENSG00000185432
PharmGKBiPA128394635
VEuPathDBiHostDB:ENSG00000185432

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4300, Eukaryota
GeneTreeiENSGT00940000154786
InParanoidiQ9H8H3
OMAiETWKYVE
OrthoDBi1178802at2759
PhylomeDBiQ9H8H3
TreeFamiTF331790

Enzyme and pathway databases

PathwayCommonsiQ9H8H3
ReactomeiR-HSA-6798695, Neutrophil degranulation
SignaLinkiQ9H8H3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		25840, 47 hits in 1041 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		METTL7A, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		25840
PharosiQ9H8H3, Tbio

Protein Ontology

More...PROi		PR:Q9H8H3
RNActiQ9H8H3, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000185432, Expressed in substantia nigra and 250 other tissues
ExpressionAtlasiQ9H8H3, baseline and differential
GenevisibleiQ9H8H3, HS

Family and domain databases

InterProiView protein in InterPro
IPR013216, Methyltransf_11
IPR029063, SAM-dependent_MTases
PfamiView protein in Pfam
PF08241, Methyltransf_11, 1 hit
SUPFAMiSSF53335, SSF53335, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMET7A_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H8H3
Secondary accession number(s): Q9H7R3, Q9UHZ7, Q9Y422
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: March 1, 2001
Last modified: February 23, 2022
This is version 160 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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