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UniProtKB - Q9H8G2 (CAAP1_HUMAN)

Entry version 137 (23 Feb 2022)
Sequence version 2 (05 Jul 2005)
Previous versions | rss
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Protein

Caspase activity and apoptosis inhibitor 1

Gene

CAAP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Anti-apoptotic protein that modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processApoptosis

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9H8G2

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9H8G2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Caspase activity and apoptosis inhibitor 1
Alternative name(s):
Conserved anti-apoptotic protein
Short name:
CAAP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CAAP1
Synonyms:C9orf82, CAAP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:25834, CAAP1

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9H8G2

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000120159

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		79886

Open Targets

More...OpenTargetsi		ENSG00000120159

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134943744

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9H8G2, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CAAP1

Domain mapping of disease mutations (DMDM)

More...DMDMi		68565300

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000897171 – 361Caspase activity and apoptosis inhibitor 1Add BLAST361

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei89PhosphoserineCombined sources1
Modified residuei90PhosphothreonineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki104Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei120PhosphoserineCombined sources1
Modified residuei203PhosphoserineCombined sources1
Modified residuei312PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9H8G2

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9H8G2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9H8G2

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9H8G2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9H8G2

PeptideAtlas

More...PeptideAtlasi		Q9H8G2

PRoteomics IDEntifications database

More...PRIDEi		Q9H8G2

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		5380
81206 [Q9H8G2-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9H8G2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9H8G2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000120159, Expressed in colonic mucosa and 235 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9H8G2, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9H8G2, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000120159, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		122971, 28 interactors

Protein interaction database and analysis system

More...IntActi		Q9H8G2, 10 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000369431

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9H8G2, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 28DisorderedSequence analysisAdd BLAST28
Regioni67 – 100DisorderedSequence analysisAdd BLAST34
Regioni198 – 218DisorderedSequence analysisAdd BLAST21
Regioni230 – 331DisorderedSequence analysisAdd BLAST102

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili281 – 311Sequence analysisAdd BLAST31

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502RN9N, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000017010

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_078683_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9H8G2

Identification of Orthologs from Complete Genome Data

More...OMAi		LQQEAKY

Database of Orthologous Groups

More...OrthoDBi		1443498at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9H8G2

TreeFam database of animal gene trees

More...TreeFami		TF332850

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR038991, CAAP1

The PANTHER Classification System

More...PANTHERi		PTHR14740, PTHR14740, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF15335, CAAP1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H8G2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTGKKSSREK RRKRSSQEAA AALAAPDIVP ALASGSSGST SGCGSAGGCG 
        60         70         80         90        100
SVSCCGNANF SGSVTGGGSG GSCWGGSSVE RSERRKRRST DSSSVSGSLQ 
       110        120        130        140        150
QETKYILPTL EKELFLAEHS DLEEGGLDLT VSLKPVSFYI SDKKEMLQQC 
       160        170        180        190        200
FCIIGEKKLQ KMLPDVLKNC SIEEIKKLCQ EQLELLSEKK ILKILEGDNG 
       210        220        230        240        250
MDSDMEEEAD DGSKMGSDLV SQQDICIDSA SSVRENKQPE GLELKQGKGE 
       260        270        280        290        300
DSDVLSINAD AYDSDIEGPC NEEAAAPEAP ENTVQSEAGQ IDDLEKDIEK 
       310        320        330        340        350
SVNEILGLAE SSPNEPKAAT LAVPPPEDVQ PSAQQLELLE LEMRARAIKA 
       360 
LMKAGDIKKP A
Length:361
Mass (Da):38,368
Last modified:July 5, 2005 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF04D8734436C0072
GO
Isoform 2 (identifier: Q9H8G2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-145: Missing.

Show »
Length:216
Mass (Da):23,511
Checksum:iE6535352FC2FC0BF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E5RFV1E5RFV1_HUMAN
Caspase activity and apoptosis inhi...
CAAP1
111Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RFW3E5RFW3_HUMAN
Caspase activity and apoptosis inhi...
CAAP1
133Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B3ISJ3A0A3B3ISJ3_HUMAN
Caspase activity and apoptosis inhi...
CAAP1
237Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti34S → G in BAB14655 (PubMed:14702039).Curated1
Sequence conflicti188E → K in AAH14658 (PubMed:15489334).Curated1
Sequence conflicti292D → N in AAH71953 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_056818233V → M. Corresponds to variant dbSNP:rs12342214Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0442531 – 145Missing in isoform 2. 1 PublicationAdd BLAST145

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK023719 mRNA Translation: BAB14655.1
AK301673 mRNA Translation: BAG63146.1
AL356133 Genomic DNA No translation available.
CH471071 Genomic DNA Translation: EAW58576.1
CH471071 Genomic DNA Translation: EAW58577.1
BC014658 mRNA Translation: AAH14658.1
BC071953 mRNA Translation: AAH71953.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS55299.1 [Q9H8G2-2]
CCDS6516.1 [Q9H8G2-1]

NCBI Reference Sequences

More...RefSeqi		NP_001161047.1, NM_001167575.1 [Q9H8G2-2]
NP_079104.3, NM_024828.3 [Q9H8G2-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000333916; ENSP00000369431; ENSG00000120159
ENST00000625311; ENSP00000487373; ENSG00000120159 [Q9H8G2-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		79886

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:79886

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000333916.8; ENSP00000369431.3; NM_024828.4; NP_079104.3

UCSC genome browser

More...UCSCi		uc003zqc.4, human [Q9H8G2-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK023719 mRNA Translation: BAB14655.1
AK301673 mRNA Translation: BAG63146.1
AL356133 Genomic DNA No translation available.
CH471071 Genomic DNA Translation: EAW58576.1
CH471071 Genomic DNA Translation: EAW58577.1
BC014658 mRNA Translation: AAH14658.1
BC071953 mRNA Translation: AAH71953.1
CCDSiCCDS55299.1 [Q9H8G2-2]
CCDS6516.1 [Q9H8G2-1]
RefSeqiNP_001161047.1, NM_001167575.1 [Q9H8G2-2]
NP_079104.3, NM_024828.3 [Q9H8G2-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi122971, 28 interactors
IntActiQ9H8G2, 10 interactors
STRINGi9606.ENSP00000369431

PTM databases

iPTMnetiQ9H8G2
PhosphoSitePlusiQ9H8G2

Genetic variation databases

BioMutaiCAAP1
DMDMi68565300

Proteomic databases

EPDiQ9H8G2
jPOSTiQ9H8G2
MassIVEiQ9H8G2
MaxQBiQ9H8G2
PaxDbiQ9H8G2
PeptideAtlasiQ9H8G2
PRIDEiQ9H8G2
ProteomicsDBi5380
81206 [Q9H8G2-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		10518, 27 antibodies from 9 providers

The DNASU plasmid repository

More...DNASUi		79886

Genome annotation databases

EnsembliENST00000333916; ENSP00000369431; ENSG00000120159
ENST00000625311; ENSP00000487373; ENSG00000120159 [Q9H8G2-2]
GeneIDi79886
KEGGihsa:79886
MANE-SelectiENST00000333916.8; ENSP00000369431.3; NM_024828.4; NP_079104.3
UCSCiuc003zqc.4, human [Q9H8G2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79886
DisGeNETi79886

GeneCards: human genes, protein and diseases

More...GeneCardsi		CAAP1
HGNCiHGNC:25834, CAAP1
HPAiENSG00000120159, Low tissue specificity
neXtProtiNX_Q9H8G2
OpenTargetsiENSG00000120159
PharmGKBiPA134943744
VEuPathDBiHostDB:ENSG00000120159

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502RN9N, Eukaryota
GeneTreeiENSGT00390000017010
HOGENOMiCLU_078683_0_0_1
InParanoidiQ9H8G2
OMAiLQQEAKY
OrthoDBi1443498at2759
PhylomeDBiQ9H8G2
TreeFamiTF332850

Enzyme and pathway databases

PathwayCommonsiQ9H8G2
SignaLinkiQ9H8G2

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		79886, 19 hits in 1047 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		CAAP1, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		C9orf82

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		79886
PharosiQ9H8G2, Tbio

Protein Ontology

More...PROi		PR:Q9H8G2
RNActiQ9H8G2, protein

Gene expression databases

BgeeiENSG00000120159, Expressed in colonic mucosa and 235 other tissues
ExpressionAtlasiQ9H8G2, baseline and differential
GenevisibleiQ9H8G2, HS

Family and domain databases

InterProiView protein in InterPro
IPR038991, CAAP1
PANTHERiPTHR14740, PTHR14740, 1 hit
PfamiView protein in Pfam
PF15335, CAAP1, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCAAP1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H8G2
Secondary accession number(s): B4DWT4
, D3DRK4, Q5VY32, Q6IPE6, Q96C59
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: July 5, 2005
Last modified: February 23, 2022
This is version 137 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
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