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Entry version 170 (07 Oct 2020)
Sequence version 3 (05 Oct 2010)
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Protein

Cysteine-rich protein 2-binding protein

Gene

KAT14

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.3.1.48, 2681

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9H8E8

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-3214847, HATs acetylate histones

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cysteine-rich protein 2-binding protein
Short name:
CSRP2-binding protein
Alternative name(s):
ADA2A-containing complex subunit 2
Short name:
ATAC2
CRP2-binding partner
Short name:
CRP2BP
Lysine acetyltransferase 14Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KAT14Imported
Synonyms:CSRP2BP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000149474.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:15904, KAT14

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
617501, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H8E8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
57325

Open Targets

More...
OpenTargetsi
ENSG00000149474

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA26969

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9H8E8, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
KAT14

Domain mapping of disease mutations (DMDM)

More...
DMDMi
308153608

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000746031 – 782Cysteine-rich protein 2-binding proteinAdd BLAST782

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei4PhosphoserineCombined sources1
Modified residuei231N6-acetyllysineBy similarity1
Modified residuei285PhosphoserineCombined sources1
Modified residuei292N6-acetyllysineCombined sources1
Modified residuei416PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H8E8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H8E8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9H8E8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H8E8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H8E8

PeptideAtlas

More...
PeptideAtlasi
Q9H8E8

PRoteomics IDEntifications database

More...
PRIDEi
Q9H8E8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
81203 [Q9H8E8-1]
81204 [Q9H8E8-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H8E8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H8E8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in skeletal muscle, heart, lung, placenta, brain, liver, pancreas and kidney. High expression in skeletal muscle and heart. Lower expression in lung.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000149474, Expressed in frontal cortex and 208 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9H8E8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H8E8, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000149474, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with the LIM 1 domain of CSRP2.

Component of the ADA2A-containing complex (ATAC), composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, MBIP and WDR5.

2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
121485, 43 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-1004, PCAF-containing ATAC complex
CPX-997, GCN5-containing ATAC complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9H8E8

Protein interaction database and analysis system

More...
IntActi
Q9H8E8, 31 interactors

Molecular INTeraction database

More...
MINTi
Q9H8E8

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000392318

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9H8E8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9H8E8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini638 – 782N-acetyltransferasePROSITE-ProRule annotationAdd BLAST145

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3138, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001146

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_022855_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H8E8

Identification of Orthologs from Complete Genome Data

More...
OMAi
PRRNWPW

Database of Orthologous Groups

More...
OrthoDBi
1404086at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H8E8

TreeFam database of animal gene trees

More...
TreeFami
TF324809

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016181, Acyl_CoA_acyltransferase
IPR000182, GNAT_dom
IPR037829, KAT14

The PANTHER Classification System

More...
PANTHERi
PTHR20916:SF0, PTHR20916:SF0, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00583, Acetyltransf_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55729, SSF55729, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51186, GNAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H8E8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDSSIHLSSL ISRHDDEATR TSTSEGLEEG EVEGETLLIV ESEDQASVDL
60 70 80 90 100
SHDQSGDSLN SDEGDVSWME EQLSYFCDKC QKWIPASQLR EQLSYLKGDN
110 120 130 140 150
FFRFTCSDCS ADGKEQYERL KLTWQQVVML AMYNLSLEGS GRQGYFRWKE
160 170 180 190 200
DICAFIEKHW TFLLGNRKKT STWWSTVAGC LSVGSPMYFR SGAQEFGEPG
210 220 230 240 250
WWKLVHNKPP TMKPEGEKLS ASTLKIKAAS KPTLDPIITV EGLRKRASRN
260 270 280 290 300
PVESAMELKE KRSRTQEAKD IRRAQKEAAG FLDRSTSSTP VKFISRGRRP
310 320 330 340 350
DVILEKGEVI DFSSLSSSDR TPLTSPSPSP SLDFSAPGTP ASHSATPSLL
360 370 380 390 400
SEADLIPDVM PPQALFHDDD EMEGDGVIDP GMEYVPPPAG SVASGPVVGV
410 420 430 440 450
RKKVRGPEQI KQEVESEEEK PDRMDIDSED TDSNTSLQTR AREKRKPQLE
460 470 480 490 500
KDTKPKEPRY TPVSIYEEKL LLKRLEACPG AVAMTPEARR LKRKLIVRQA
510 520 530 540 550
KRDRGLPLFD LDQVVNAALL LVDGIYGAKE GGISRLPAGQ ATYRTTCQDF
560 570 580 590 600
RILDRYQTSL PSRKGFRHQT TKFLYRLVGS EDMAVDQSIV SPYTSRILKP
610 620 630 640 650
YIRRDYETKP PKLQLLSQIR SHLHRSDPHW TPEPDAPLDY CYVRPNHIPT
660 670 680 690 700
INSMCQEFFW PGIDLSECLQ YPDFSVVVLY KKVIIAFGFM VPDVKYNEAY
710 720 730 740 750
ISFLFVHPEW RRAGIATFMI YHLIQTCMGK DVTLHVSASN PAMLLYQKFG
760 770 780
FKTEEYVLDF YDKYYPLEST ECKHAFFLRL RR
Length:782
Mass (Da):88,844
Last modified:October 5, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE84FAEF06412EA77
GO
Isoform 2 (identifier: Q9H8E8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-128: Missing.

Note: May be due to an intron retention.Curated
Show »
Length:654
Mass (Da):74,324
Checksum:i2EA7F2981E7D4195
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A075B6H4A0A075B6H4_HUMAN
Cysteine-rich protein 2-binding pro...
KAT14
781Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RAU4D6RAU4_HUMAN
Cysteine-rich protein 2-binding pro...
KAT14
56Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti535R → G in BAB14669 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_028034214P → L. Corresponds to variant dbSNP:rs6081011Ensembl.1
Natural variantiVAR_028035400V → G2 PublicationsCorresponds to variant dbSNP:rs1205193Ensembl.1
Natural variantiVAR_020466442R → T. Corresponds to variant dbSNP:rs2295182Ensembl.1
Natural variantiVAR_033839600P → R. Corresponds to variant dbSNP:rs11557577Ensembl.1
Natural variantiVAR_048166738A → S. Corresponds to variant dbSNP:rs6081027Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0000701 – 128Missing in isoform 2. 2 PublicationsAdd BLAST128

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK023759 mRNA Translation: BAB14669.1
AL050321 Genomic DNA No translation available.
CH471133 Genomic DNA Translation: EAX10255.1
BC007537 mRNA Translation: AAH07537.1
BC009174 mRNA No translation available.
AF252257 mRNA Translation: AAG10249.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13133.1 [Q9H8E8-1]

NCBI Reference Sequences

More...
RefSeqi
NP_065397.3, NM_020536.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000435364; ENSP00000392318; ENSG00000149474 [Q9H8E8-1]
ENST00000489634; ENSP00000425909; ENSG00000149474 [Q9H8E8-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57325

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:57325

UCSC genome browser

More...
UCSCi
uc002wqk.3, human [Q9H8E8-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK023759 mRNA Translation: BAB14669.1
AL050321 Genomic DNA No translation available.
CH471133 Genomic DNA Translation: EAX10255.1
BC007537 mRNA Translation: AAH07537.1
BC009174 mRNA No translation available.
AF252257 mRNA Translation: AAG10249.1
CCDSiCCDS13133.1 [Q9H8E8-1]
RefSeqiNP_065397.3, NM_020536.4

3D structure databases

SMRiQ9H8E8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi121485, 43 interactors
ComplexPortaliCPX-1004, PCAF-containing ATAC complex
CPX-997, GCN5-containing ATAC complex
CORUMiQ9H8E8
IntActiQ9H8E8, 31 interactors
MINTiQ9H8E8
STRINGi9606.ENSP00000392318

PTM databases

iPTMnetiQ9H8E8
PhosphoSitePlusiQ9H8E8

Polymorphism and mutation databases

BioMutaiKAT14
DMDMi308153608

Proteomic databases

EPDiQ9H8E8
jPOSTiQ9H8E8
MassIVEiQ9H8E8
MaxQBiQ9H8E8
PaxDbiQ9H8E8
PeptideAtlasiQ9H8E8
PRIDEiQ9H8E8
ProteomicsDBi81203 [Q9H8E8-1]
81204 [Q9H8E8-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
24530, 152 antibodies

The DNASU plasmid repository

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DNASUi
57325

Genome annotation databases

EnsembliENST00000435364; ENSP00000392318; ENSG00000149474 [Q9H8E8-1]
ENST00000489634; ENSP00000425909; ENSG00000149474 [Q9H8E8-2]
GeneIDi57325
KEGGihsa:57325
UCSCiuc002wqk.3, human [Q9H8E8-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
57325
DisGeNETi57325
EuPathDBiHostDB:ENSG00000149474.13

GeneCards: human genes, protein and diseases

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GeneCardsi
KAT14
HGNCiHGNC:15904, KAT14
HPAiENSG00000149474, Low tissue specificity
MIMi617501, gene
neXtProtiNX_Q9H8E8
OpenTargetsiENSG00000149474
PharmGKBiPA26969

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG3138, Eukaryota
GeneTreeiENSGT00390000001146
HOGENOMiCLU_022855_0_0_1
InParanoidiQ9H8E8
OMAiPRRNWPW
OrthoDBi1404086at2759
PhylomeDBiQ9H8E8
TreeFamiTF324809

Enzyme and pathway databases

BRENDAi2.3.1.48, 2681
PathwayCommonsiQ9H8E8
ReactomeiR-HSA-3214847, HATs acetylate histones

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
57325, 22 hits in 867 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
KAT14, human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
CSRP2BP

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
57325
PharosiQ9H8E8, Tbio

Protein Ontology

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PROi
PR:Q9H8E8
RNActiQ9H8E8, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000149474, Expressed in frontal cortex and 208 other tissues
ExpressionAtlasiQ9H8E8, baseline and differential
GenevisibleiQ9H8E8, HS

Family and domain databases

InterProiView protein in InterPro
IPR016181, Acyl_CoA_acyltransferase
IPR000182, GNAT_dom
IPR037829, KAT14
PANTHERiPTHR20916:SF0, PTHR20916:SF0, 1 hit
PfamiView protein in Pfam
PF00583, Acetyltransf_1, 1 hit
SUPFAMiSSF55729, SSF55729, 1 hit
PROSITEiView protein in PROSITE
PS51186, GNAT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCSR2B_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H8E8
Secondary accession number(s): A2A2I5
, Q96GW6, Q96IH3, Q9HBF0, Q9UIY5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: October 5, 2010
Last modified: October 7, 2020
This is version 170 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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