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Entry version 140 (16 Oct 2019)
Sequence version 1 (01 Mar 2001)
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Protein

5'-nucleotidase domain-containing protein 2

Gene

NT5DC2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei73NucleophileBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi73MagnesiumBy similarity1
Active sitei75Proton donorBy similarity1
Metal bindingi75Magnesium; via carbonyl oxygenBy similarity1
Metal bindingi358MagnesiumBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
LigandMagnesium, Metal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
5'-nucleotidase domain-containing protein 2 (EC:3.1.3.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NT5DC2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25717 NT5DC2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H857

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
64943

Open Targets

More...
OpenTargetsi
ENSG00000168268

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA143485561

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9H857

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NT5DC2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74733765

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002472241 – 5205'-nucleotidase domain-containing protein 2Add BLAST520

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H857

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H857

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9H857

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H857

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H857

PeptideAtlas

More...
PeptideAtlasi
Q9H857

PRoteomics IDEntifications database

More...
PRIDEi
Q9H857

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
11660
19043
81179 [Q9H857-1]
81180 [Q9H857-2]
81181 [Q9H857-3]
81182 [Q9H857-4]

PTM databases

DEPOD human dephosphorylation database

More...
DEPODi
Q9H857

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H857

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H857

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9H857

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000168268 Expressed in 163 organ(s), highest expression level in left coronary artery

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9H857 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H857 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA050683

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122353, 27 interactors

Protein interaction database and analysis system

More...
IntActi
Q9H857, 19 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000406933

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9H857

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2470 Eukaryota
ENOG410XT8W LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159940

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000230610

Identification of Orthologs from Complete Genome Data

More...
OMAi
KWIEKDM

Database of Orthologous Groups

More...
OrthoDBi
858908at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H857

TreeFam database of animal gene trees

More...
TreeFami
TF323990

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.1000, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036412 HAD-like_sf
IPR008380 HAD-SF_hydro_IG_5-nucl
IPR023214 HAD_sf
IPR016695 Pur_nucleotidase

The PANTHER Classification System

More...
PANTHERi
PTHR12103 PTHR12103, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05761 5_nucleotid, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF017434 Purine_5'-nucleotidase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56784 SSF56784, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR02244 HAD-IG-Ncltidse, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H857-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRVESGSAQE RGILLESLST LLEKTTASHE GRAPGNRELT DLLPPEVCSL
60 70 80 90 100
LNPAAIYANN EISLRDVEVY GFDYDYTLAQ YADALHPEIF STARDILIEH
110 120 130 140 150
YKYPEGIRKY DYNPSFAIRG LHYDIQKSLL MKIDAFHYVQ LGTAYRGLQP
160 170 180 190 200
VPDEEVIELY GGTQHIPLYQ MSGFYGKGPS IKQFMDIFSL PEMALLSCVV
210 220 230 240 250
DYFLGHSLEF DQAHLYKDVT DAIRDVHVKG LMYQWIEQDM EKYILRGDET
260 270 280 290 300
FAVLSRLVAH GKQLFLITNS PFSFVDKGMR HMVGPDWRQL FDVVIVQADK
310 320 330 340 350
PSFFTDRRKP FRKLDEKGSL QWDRITRLEK GKIYRQGNLF DFLRLTEWRG
360 370 380 390 400
PRVLYFGDHL YSDLADLMLR HGWRTGAIIP ELEREIRIIN TEQYMHSLTW
410 420 430 440 450
QQALTGLLER MQTYQDAESR QVLAAWMKER QELRCITKAL FNAQFGSIFR
460 470 480 490 500
TFHNPTYFSR RLVRFSDLYM ASLSCLLNYR VDFTFYPRRT PLQHEAPLWM
510 520
DQLCTGCMKT PFLGDMAHIR
Length:520
Mass (Da):60,719
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB80C050D404178ED
GO
Isoform 2 (identifier: Q9H857-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-40: MRVESGSAQE...GRAPGNRELT → MAGAGLRAAA...RYQDMRRLVH

Note: No experimental confirmation available.
Show »
Length:557
Mass (Da):64,145
Checksum:iD366C10C1AAFCD01
GO
Isoform 3 (identifier: Q9H857-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-40: MRVESGSAQE...GRAPGNRELT → MAGAGLRAAA...RYQDMRRLVH
     103-127: Missing.

Note: No experimental confirmation available.
Show »
Length:532
Mass (Da):61,118
Checksum:i409B0BD2C78A4E9A
GO
Isoform 4 (identifier: Q9H857-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-130: Missing.

Note: No experimental confirmation available.
Show »
Length:390
Mass (Da):45,998
Checksum:iD51C366CDC4A108B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WEY1F8WEY1_HUMAN
5'-nucleotidase domain-containing p...
NT5DC2
111Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C4G8H7C4G8_HUMAN
5'-nucleotidase domain-containing p...
NT5DC2
258Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C519H7C519_HUMAN
5'-nucleotidase domain-containing p...
NT5DC2
194Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J036C9J036_HUMAN
5'-nucleotidase domain-containing p...
NT5DC2
85Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH14550 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAB14064 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti59N → D in BAB14064 (PubMed:14702039).Curated1
Sequence conflicti475C → R in BAB14064 (PubMed:14702039).Curated1
Sequence conflicti491P → S in BAB14064 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03414391S → R. Corresponds to variant dbSNP:rs35920544Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0199511 – 130Missing in isoform 4. 1 PublicationAdd BLAST130
Alternative sequenceiVSP_0199521 – 40MRVES…NRELT → MAGAGLRAAARRWLLCGGHG GPRAASSSPSCPGCGPPGPG AHCPGVPRSAPAQAPTSGAD LSAHLWARYQDMRRLVH in isoform 2 and isoform 3. CuratedAdd BLAST40
Alternative sequenceiVSP_019953103 – 127Missing in isoform 3. CuratedAdd BLAST25

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF131781 mRNA Translation: AAD20044.1
AK022504 mRNA Translation: BAB14064.1 Different initiation.
AK023995 mRNA Translation: BAB14763.1
AC112215 Genomic DNA No translation available.
BC014550 mRNA Translation: AAH14550.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2858.1 [Q9H857-1]
CCDS46843.1 [Q9H857-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001127703.1, NM_001134231.1 [Q9H857-2]
NP_075059.1, NM_022908.2 [Q9H857-1]
XP_005265463.1, XM_005265406.2 [Q9H857-4]
XP_006713368.1, XM_006713305.2 [Q9H857-4]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000307076; ENSP00000302468; ENSG00000168268 [Q9H857-1]
ENST00000422318; ENSP00000406933; ENSG00000168268 [Q9H857-2]
ENST00000459839; ENSP00000419547; ENSG00000168268 [Q9H857-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
64943

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:64943

UCSC genome browser

More...
UCSCi
uc003den.4 human [Q9H857-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF131781 mRNA Translation: AAD20044.1
AK022504 mRNA Translation: BAB14064.1 Different initiation.
AK023995 mRNA Translation: BAB14763.1
AC112215 Genomic DNA No translation available.
BC014550 mRNA Translation: AAH14550.1 Different initiation.
CCDSiCCDS2858.1 [Q9H857-1]
CCDS46843.1 [Q9H857-2]
RefSeqiNP_001127703.1, NM_001134231.1 [Q9H857-2]
NP_075059.1, NM_022908.2 [Q9H857-1]
XP_005265463.1, XM_005265406.2 [Q9H857-4]
XP_006713368.1, XM_006713305.2 [Q9H857-4]

3D structure databases

SMRiQ9H857
ModBaseiSearch...

Protein-protein interaction databases

BioGridi122353, 27 interactors
IntActiQ9H857, 19 interactors
STRINGi9606.ENSP00000406933

PTM databases

DEPODiQ9H857
iPTMnetiQ9H857
PhosphoSitePlusiQ9H857
SwissPalmiQ9H857

Polymorphism and mutation databases

BioMutaiNT5DC2
DMDMi74733765

Proteomic databases

EPDiQ9H857
jPOSTiQ9H857
MassIVEiQ9H857
MaxQBiQ9H857
PaxDbiQ9H857
PeptideAtlasiQ9H857
PRIDEiQ9H857
ProteomicsDBi11660
19043
81179 [Q9H857-1]
81180 [Q9H857-2]
81181 [Q9H857-3]
81182 [Q9H857-4]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
64943

Genome annotation databases

EnsembliENST00000307076; ENSP00000302468; ENSG00000168268 [Q9H857-1]
ENST00000422318; ENSP00000406933; ENSG00000168268 [Q9H857-2]
ENST00000459839; ENSP00000419547; ENSG00000168268 [Q9H857-3]
GeneIDi64943
KEGGihsa:64943
UCSCiuc003den.4 human [Q9H857-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
64943
DisGeNETi64943

GeneCards: human genes, protein and diseases

More...
GeneCardsi
NT5DC2
HGNCiHGNC:25717 NT5DC2
HPAiHPA050683
neXtProtiNX_Q9H857
OpenTargetsiENSG00000168268
PharmGKBiPA143485561

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2470 Eukaryota
ENOG410XT8W LUCA
GeneTreeiENSGT00940000159940
HOGENOMiHOG000230610
OMAiKWIEKDM
OrthoDBi858908at2759
PhylomeDBiQ9H857
TreeFamiTF323990

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
NT5DC2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
64943
PharosiQ9H857

Protein Ontology

More...
PROi
PR:Q9H857

Gene expression databases

BgeeiENSG00000168268 Expressed in 163 organ(s), highest expression level in left coronary artery
ExpressionAtlasiQ9H857 baseline and differential
GenevisibleiQ9H857 HS

Family and domain databases

Gene3Di3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR036412 HAD-like_sf
IPR008380 HAD-SF_hydro_IG_5-nucl
IPR023214 HAD_sf
IPR016695 Pur_nucleotidase
PANTHERiPTHR12103 PTHR12103, 1 hit
PfamiView protein in Pfam
PF05761 5_nucleotid, 1 hit
PIRSFiPIRSF017434 Purine_5'-nucleotidase, 1 hit
SUPFAMiSSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR02244 HAD-IG-Ncltidse, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNT5D2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H857
Secondary accession number(s): C9JTZ6
, E9PAL9, O95888, Q96C80, Q9H9Z8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: March 1, 2001
Last modified: October 16, 2019
This is version 140 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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