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Protein

Gem-associated protein 7

Gene

GEMIN7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • import into nucleus Source: Reactome
  • mRNA splicing, via spliceosome Source: UniProtKB
  • spliceosomal snRNP assembly Source: UniProtKB

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processmRNA processing, mRNA splicing

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-191859 snRNP Assembly

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q9H840

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Gem-associated protein 7
Short name:
Gemin-7
Alternative name(s):
SIP3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GEMIN7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000142252.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:20045 GEMIN7

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
607419 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H840

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
79760

Open Targets

More...
OpenTargetsi
ENSG00000142252

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134959810

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
GEMIN7

Domain mapping of disease mutations (DMDM)

More...
DMDMi
34922127

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000874621 – 131Gem-associated protein 7Add BLAST131

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei3PhosphothreonineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H840

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H840

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H840

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H840

PeptideAtlas

More...
PeptideAtlasi
Q9H840

PRoteomics IDEntifications database

More...
PRIDEi
Q9H840

ProteomicsDB human proteome resource

More...
ProteomicsDBi
81175

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H840

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H840

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000142252 Expressed in 157 organ(s), highest expression level in prostate gland

CleanEx database of gene expression profiles

More...
CleanExi
HS_GEMIN7

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H840 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA052075

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the core SMN complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8 and STRAP/UNRIP. Part of the SMN-Sm complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, STRAP/UNRIP and the Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG. Interacts directly with GEMIN6, SNRPB, SNRPD2, SNRPD3 and SNRPE.3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
GEMIN6Q8WXD515EBI-715455,EBI-752301

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
122869, 45 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9H840

Database of interacting proteins

More...
DIPi
DIP-41750N

Protein interaction database and analysis system

More...
IntActi
Q9H840, 36 interactors

Molecular INTeraction database

More...
MINTi
Q9H840

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000270257

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1131
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1Y96X-ray2.00B/D47-131[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9H840

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q9H840

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9H840

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the gemin-7 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IYUI Eukaryota
ENOG410XZWW LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000018039

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000112710

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG051723

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H840

KEGG Orthology (KO)

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KOi
K13135

Identification of Orthologs from Complete Genome Data

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OMAi
DPNSRGF

Database of Orthologous Groups

More...
OrthoDBi
1517114at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H840

Family and domain databases

Conserved Domains Database

More...
CDDi
cd11677 Gemin7, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020338 SMN_gemin7

The PANTHER Classification System

More...
PANTHERi
PTHR14679 PTHR14679, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF11095 Gemin7, 1 hit

ProDom; a protein domain database

More...
ProDomi
View protein in ProDom or Entries sharing at least one domain
PD296126 SMN_cplx_gem-assoc_protein_7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9H840-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQTPVNIPVP VLRLPRGPDG FSRGFAPDGR RAPLRPEVPE IQECPIAQES
60 70 80 90 100
LESQEQRARA ALRERYLRSL LAMVGHQVSF TLHEGVRVAA HFGATDLDVA
110 120 130
NFYVSQLQTP IGVQAEALLR CSDIISYTFK P
Length:131
Mass (Da):14,537
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6E118922AFDCF567
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY114106 mRNA Translation: AAM44083.1
AK024018 mRNA Translation: BAB14780.1
CR457321 mRNA Translation: CAG33602.1
CH471126 Genomic DNA Translation: EAW57321.1
BC007793 mRNA Translation: AAH07793.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12654.1

NCBI Reference Sequences

More...
RefSeqi
NP_001007270.1, NM_001007269.1
NP_001007271.1, NM_001007270.1
NP_001305983.1, NM_001319054.1
NP_001305984.1, NM_001319055.1
NP_078983.1, NM_024707.2
XP_005259319.1, XM_005259262.3
XP_005259320.1, XM_005259263.4
XP_016882801.1, XM_017027312.1

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.466919

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000270257; ENSP00000270257; ENSG00000142252
ENST00000391951; ENSP00000375813; ENSG00000142252
ENST00000591607; ENSP00000466342; ENSG00000142252
ENST00000591747; ENSP00000465704; ENSG00000142252

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79760

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79760

UCSC genome browser

More...
UCSCi
uc002pap.2 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY114106 mRNA Translation: AAM44083.1
AK024018 mRNA Translation: BAB14780.1
CR457321 mRNA Translation: CAG33602.1
CH471126 Genomic DNA Translation: EAW57321.1
BC007793 mRNA Translation: AAH07793.1
CCDSiCCDS12654.1
RefSeqiNP_001007270.1, NM_001007269.1
NP_001007271.1, NM_001007270.1
NP_001305983.1, NM_001319054.1
NP_001305984.1, NM_001319055.1
NP_078983.1, NM_024707.2
XP_005259319.1, XM_005259262.3
XP_005259320.1, XM_005259263.4
XP_016882801.1, XM_017027312.1
UniGeneiHs.466919

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1Y96X-ray2.00B/D47-131[»]
ProteinModelPortaliQ9H840
SMRiQ9H840
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122869, 45 interactors
CORUMiQ9H840
DIPiDIP-41750N
IntActiQ9H840, 36 interactors
MINTiQ9H840
STRINGi9606.ENSP00000270257

PTM databases

iPTMnetiQ9H840
PhosphoSitePlusiQ9H840

Polymorphism and mutation databases

BioMutaiGEMIN7
DMDMi34922127

Proteomic databases

EPDiQ9H840
jPOSTiQ9H840
MaxQBiQ9H840
PaxDbiQ9H840
PeptideAtlasiQ9H840
PRIDEiQ9H840
ProteomicsDBi81175

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000270257; ENSP00000270257; ENSG00000142252
ENST00000391951; ENSP00000375813; ENSG00000142252
ENST00000591607; ENSP00000466342; ENSG00000142252
ENST00000591747; ENSP00000465704; ENSG00000142252
GeneIDi79760
KEGGihsa:79760
UCSCiuc002pap.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79760
DisGeNETi79760
EuPathDBiHostDB:ENSG00000142252.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
GEMIN7
HGNCiHGNC:20045 GEMIN7
HPAiHPA052075
MIMi607419 gene
neXtProtiNX_Q9H840
OpenTargetsiENSG00000142252
PharmGKBiPA134959810

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IYUI Eukaryota
ENOG410XZWW LUCA
GeneTreeiENSGT00390000018039
HOGENOMiHOG000112710
HOVERGENiHBG051723
InParanoidiQ9H840
KOiK13135
OMAiDPNSRGF
OrthoDBi1517114at2759
PhylomeDBiQ9H840

Enzyme and pathway databases

ReactomeiR-HSA-191859 snRNP Assembly
SIGNORiQ9H840

Miscellaneous databases

EvolutionaryTraceiQ9H840

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
79760

Protein Ontology

More...
PROi
PR:Q9H840

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000142252 Expressed in 157 organ(s), highest expression level in prostate gland
CleanExiHS_GEMIN7
GenevisibleiQ9H840 HS

Family and domain databases

CDDicd11677 Gemin7, 1 hit
InterProiView protein in InterPro
IPR020338 SMN_gemin7
PANTHERiPTHR14679 PTHR14679, 1 hit
PfamiView protein in Pfam
PF11095 Gemin7, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD296126 SMN_cplx_gem-assoc_protein_7, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGEMI7_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H840
Secondary accession number(s): Q6IA34
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: March 1, 2001
Last modified: January 16, 2019
This is version 152 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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