Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 132 (16 Oct 2019)
Sequence version 1 (01 Mar 2001)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Intraflagellar transport protein 22 homolog

Gene

IFT22

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Small GTPase-like component of the intraflagellar transport (IFT) complex B.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi10 – 17GTPBy similarity8
Nucleotide bindingi63 – 67GTPBy similarity5
Nucleotide bindingi123 – 126GTPBy similarity4

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5620924 Intraflagellar transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Intraflagellar transport protein 22 homolog
Alternative name(s):
Rab-like protein 5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:IFT22
Synonyms:RABL5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21895 IFT22

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H7X7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000128581

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134871769

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9H7X7

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
IFT22

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74733725

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002537331 – 185Intraflagellar transport protein 22 homologAdd BLAST185

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei137PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H7X7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H7X7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9H7X7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H7X7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H7X7

PeptideAtlas

More...
PeptideAtlasi
Q9H7X7

PRoteomics IDEntifications database

More...
PRIDEi
Q9H7X7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
62041
81155 [Q9H7X7-1]
81156 [Q9H7X7-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H7X7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H7X7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000128581 Expressed in 215 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9H7X7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H7X7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA042930

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the IFT complex B, at least composed of IFT20, IFT22, HSPB11/IFT25, IFT27, IFT46, IFT52, TRAF3IP1/IFT54, IFT57, IFT74, IFT80, IFT81, and IFT88.

Interacts with IFT88 (By similarity).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122300, 42 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9H7X7

Protein interaction database and analysis system

More...
IntActi
Q9H7X7, 25 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000320359

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IVWX Eukaryota
ENOG4111FYS LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013187

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000232131

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H7X7

KEGG Orthology (KO)

More...
KOi
K07935

Identification of Orthologs from Complete Genome Data

More...
OMAi
GDQKFET

Database of Orthologous Groups

More...
OrthoDBi
1428809at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H7X7

TreeFam database of animal gene trees

More...
TreeFami
TF313208

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027417 P-loop_NTPase

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H7X7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLKAKILFVG PCESGKTVLA NFLTESSDIT EYSPTQGVRI LEFENPHVTS
60 70 80 90 100
NNKGTGCEFE LWDCGGDAKF ESCWPALMKD AHGVVIVFNA DIPSHRKEME
110 120 130 140 150
MWYSCFVQQP SLQDTQCMLI AHHKPGSGDD KGSLSLSPPL NKLKLVHSNL
160 170 180
EDDPEEIRME FIKYLKSIIN SMSESRDREE MSIMT
Length:185
Mass (Da):20,835
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i993D2ECEFE14A673
GO
Isoform 2 (identifier: Q9H7X7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     40-69: Missing.

Show »
Length:155
Mass (Da):17,541
Checksum:iEB372AFB4478E72E
GO
Isoform 3 (identifier: Q9H7X7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-77: Missing.

Show »
Length:108
Mass (Da):12,393
Checksum:i534B53C72D506620
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WDY0F8WDY0_HUMAN
Intraflagellar transport protein 22...
IFT22
37Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0451821 – 77Missing in isoform 3. 2 PublicationsAdd BLAST77
Alternative sequenceiVSP_02111240 – 69Missing in isoform 2. 1 PublicationAdd BLAST30

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK023287 mRNA Translation: BAG51181.1
AK024179 mRNA Translation: BAB14846.1
AK298888 mRNA Translation: BAH12896.1
AC006329 Genomic DNA No translation available.
CH471197 Genomic DNA Translation: EAW50217.1
BC004522 mRNA Translation: AAH04522.1
BC009823 mRNA Translation: AAH09823.1
BC038668 mRNA Translation: AAH38668.1
AL157469 mRNA Translation: CAH10693.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47670.1 [Q9H7X7-2]
CCDS47671.1 [Q9H7X7-3]
CCDS5719.1 [Q9H7X7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001124292.1, NM_001130820.2 [Q9H7X7-2]
NP_001124293.1, NM_001130821.2 [Q9H7X7-3]
NP_001124294.1, NM_001130822.2 [Q9H7X7-3]
NP_001274454.1, NM_001287525.1 [Q9H7X7-3]
NP_001274455.1, NM_001287526.1 [Q9H7X7-3]
NP_073614.1, NM_022777.3 [Q9H7X7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000315322; ENSP00000320359; ENSG00000128581 [Q9H7X7-1]
ENST00000422177; ENSP00000392087; ENSG00000128581 [Q9H7X7-1]
ENST00000437644; ENSP00000390770; ENSG00000128581 [Q9H7X7-2]
ENST00000498704; ENSP00000429648; ENSG00000128581 [Q9H7X7-3]
ENST00000517481; ENSP00000429202; ENSG00000128581 [Q9H7X7-3]
ENST00000621899; ENSP00000478948; ENSG00000128581 [Q9H7X7-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
64792

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:64792

UCSC genome browser

More...
UCSCi
uc003uyl.5 human [Q9H7X7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK023287 mRNA Translation: BAG51181.1
AK024179 mRNA Translation: BAB14846.1
AK298888 mRNA Translation: BAH12896.1
AC006329 Genomic DNA No translation available.
CH471197 Genomic DNA Translation: EAW50217.1
BC004522 mRNA Translation: AAH04522.1
BC009823 mRNA Translation: AAH09823.1
BC038668 mRNA Translation: AAH38668.1
AL157469 mRNA Translation: CAH10693.1
CCDSiCCDS47670.1 [Q9H7X7-2]
CCDS47671.1 [Q9H7X7-3]
CCDS5719.1 [Q9H7X7-1]
RefSeqiNP_001124292.1, NM_001130820.2 [Q9H7X7-2]
NP_001124293.1, NM_001130821.2 [Q9H7X7-3]
NP_001124294.1, NM_001130822.2 [Q9H7X7-3]
NP_001274454.1, NM_001287525.1 [Q9H7X7-3]
NP_001274455.1, NM_001287526.1 [Q9H7X7-3]
NP_073614.1, NM_022777.3 [Q9H7X7-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi122300, 42 interactors
CORUMiQ9H7X7
IntActiQ9H7X7, 25 interactors
STRINGi9606.ENSP00000320359

PTM databases

iPTMnetiQ9H7X7
PhosphoSitePlusiQ9H7X7

Polymorphism and mutation databases

BioMutaiIFT22
DMDMi74733725

Proteomic databases

EPDiQ9H7X7
jPOSTiQ9H7X7
MassIVEiQ9H7X7
MaxQBiQ9H7X7
PaxDbiQ9H7X7
PeptideAtlasiQ9H7X7
PRIDEiQ9H7X7
ProteomicsDBi62041
81155 [Q9H7X7-1]
81156 [Q9H7X7-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
64792

Genome annotation databases

EnsembliENST00000315322; ENSP00000320359; ENSG00000128581 [Q9H7X7-1]
ENST00000422177; ENSP00000392087; ENSG00000128581 [Q9H7X7-1]
ENST00000437644; ENSP00000390770; ENSG00000128581 [Q9H7X7-2]
ENST00000498704; ENSP00000429648; ENSG00000128581 [Q9H7X7-3]
ENST00000517481; ENSP00000429202; ENSG00000128581 [Q9H7X7-3]
ENST00000621899; ENSP00000478948; ENSG00000128581 [Q9H7X7-3]
GeneIDi64792
KEGGihsa:64792
UCSCiuc003uyl.5 human [Q9H7X7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
64792

GeneCards: human genes, protein and diseases

More...
GeneCardsi
IFT22
HGNCiHGNC:21895 IFT22
HPAiHPA042930
neXtProtiNX_Q9H7X7
OpenTargetsiENSG00000128581
PharmGKBiPA134871769

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IVWX Eukaryota
ENOG4111FYS LUCA
GeneTreeiENSGT00390000013187
HOGENOMiHOG000232131
InParanoidiQ9H7X7
KOiK07935
OMAiGDQKFET
OrthoDBi1428809at2759
PhylomeDBiQ9H7X7
TreeFamiTF313208

Enzyme and pathway databases

ReactomeiR-HSA-5620924 Intraflagellar transport

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
IFT22 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
64792
PharosiQ9H7X7

Protein Ontology

More...
PROi
PR:Q9H7X7

Gene expression databases

BgeeiENSG00000128581 Expressed in 215 organ(s), highest expression level in testis
ExpressionAtlasiQ9H7X7 baseline and differential
GenevisibleiQ9H7X7 HS

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
SUPFAMiSSF52540 SSF52540, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIFT22_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H7X7
Secondary accession number(s): Q49AG1, Q69YV5, Q9BSW4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: March 1, 2001
Last modified: October 16, 2019
This is version 132 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again