Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 141 (29 Sep 2021)
Sequence version 2 (24 Jul 2007)
Previous versions | rss
Add a publicationFeedback
Protein

Cation channel sperm-associated protein subunit beta

Gene

CATSPERB

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processDifferentiation, Spermatogenesis

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9H7T0

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-1300642, Sperm Motility And Taxes

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.1.19.1, the voltage-gated ion channel (vic) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cation channel sperm-associated protein subunit beta
Short name:
CatSper-beta
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CATSPERB
Synonyms:C14orf161
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:20500, CATSPERB

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611169, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H7T0

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000133962

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Transmembranei193 – 213HelicalSequence analysisAdd BLAST21
Transmembranei244 – 264HelicalSequence analysisAdd BLAST21
Transmembranei1058 – 1078HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
79820

Open Targets

More...
OpenTargetsi
ENSG00000133962

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162381112

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9H7T0, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CATSPERB

Domain mapping of disease mutations (DMDM)

More...
DMDMi
158519875

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000899531 – 1116Cation channel sperm-associated protein subunit betaAdd BLAST1116

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi90N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi100N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi118N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi226N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi321N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H7T0

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H7T0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9H7T0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H7T0

PeptideAtlas

More...
PeptideAtlasi
Q9H7T0

PRoteomics IDEntifications database

More...
PRIDEi
Q9H7T0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
81144 [Q9H7T0-1]
81145 [Q9H7T0-2]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q9H7T0, 5 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H7T0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H7T0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000133962, Expressed in body of pancreas and 111 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9H7T0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H7T0, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000133962, Tissue enhanced (pancreas)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the CatSper complex.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
122915, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000256343

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9H7T0, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QZ5S, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000008198

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_012454_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H7T0

Identification of Orthologs from Complete Genome Data

More...
OMAi
KEPFLEW

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H7T0

TreeFam database of animal gene trees

More...
TreeFami
TF328432

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028748, CATSPERB

The PANTHER Classification System

More...
PANTHERi
PTHR14705, PTHR14705, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15149, CATSPERB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H7T0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MESPLIYVSV LLLNIFEFSS GIVYNKDDTE KRFACSNKGF PQENEIIKLY
60 70 80 90 100
LFLENLKIQC FFQTENEIAS KAMLSVFTSG GLAPSLGIMN STYNGIFHFN
110 120 130 140 150
LTLFSDRILW LVDIPRENIT QSTDIAAVEE WLVRITLHHG LNIYATEGTL
160 170 180 190 200
LDVIREPILQ WTPGDVIPES EISKLYPHVV DLKVTKCPCA NDVALLGFIV
210 220 230 240 250
DTIVDGVYIG ITFGGFWHDY DTTWFNMTQT IYSQLQEEYE DLSLVDMVLT
260 270 280 290 300
NHFLVILTSL GLFVSEDLRY PSRHSLSFSR ADFCGFERVD YVKGKLWYNE
310 320 330 340 350
RCFANREHFE VDYVTVTFER NRTLSESSSC FYSQEPFLEW VPCLPHIFKG
360 370 380 390 400
IKIFPTVLTF LVDQERGTGV YLFYNKVRKT AIASVSTLRN NEPNSQSKFP
410 420 430 440 450
IFRFPSSFSS PVGMVFHPRS HFLYAYGNQI WLSVDGGNTF QLIANFHDDI
460 470 480 490 500
IKKTFHSFYT SAITFVSQRG KVYSTKAGMG RYSAVGSVTE RIFTLYYDHL
510 520 530 540 550
GFLHKLTLGR FEASGPPTAF GNSRNLFGQP PDMGFETALA PQHTSLDEII
560 570 580 590 600
FFAYVPENEP QETIYSKKFG NIHYGKVIHS GKTGRAYIRK VLQHTTPKGF
610 620 630 640 650
LSSVIAEMKE PFGLEEVNES SCLSSSLLIN KAGNVYKLTL DSQVVQALFE
660 670 680 690 700
DTDIEKTVVL PGYSSFLITS ILDNKNALAI ATMPESAPNN MTFLKSTWFL
710 720 730 740 750
YNFGQRNGRT WKIYSKPCNY WFQHDDSPSL NIVKYIDLGN SYVLKAKVIR
760 770 780 790 800
NAKGFRMLEI PLLTVFVGNP NLLEVTAEVT FDDTDSYVIT ISAASKVLHQ
810 820 830 840 850
GSTSLAFIMW SASTECFVTT MVPTLKSSCS YLRSMHHIPS KFIPFEDWIS
860 870 880 890 900
GVHKDSQGFN LIKTLPINYR PPSNMGIAIP LTDNFYHADP SKPIPRNMFH
910 920 930 940 950
MSKKTGKFKQ CANVSTREEC NCTKDQKFSH AVAFSDCREK VPRFKFPITQ
960 970 980 990 1000
YPVSLEIINE DGRVPLQSPY LVTVTEVNMR HNWKLKHTVP ENIKRMKQLV
1010 1020 1030 1040 1050
EPILGAAVYN PSGLNLSIKG SELFHFRVTV ISGVTFCNLI EEFQIYVDEA
1060 1070 1080 1090 1100
PLPFPGHTLI AVATAVVLGG LIFIAFMFQL QGIHPWRTFQ RWIRRNQEKF
1110
SSISLSELIH RSKSEE
Length:1,116
Mass (Da):126,924
Last modified:July 24, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3A5DB4D5E2C1C81E
GO
Isoform 2 (identifier: Q9H7T0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-478: Missing.

Show »
Length:638
Mass (Da):72,092
Checksum:i45396A81ACEBC7AC
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3V584G3V584_HUMAN
Cation channel sperm-associated pro...
CATSPERB
100Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3V2V0G3V2V0_HUMAN
Cation channel sperm-associated pro...
CATSPERB
150Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3V352G3V352_HUMAN
Cation channel sperm-associated pro...
CATSPERB
73Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GXC6A0A1B0GXC6_HUMAN
Cation channel sperm-associated pro...
CATSPERB
74Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YJA5H0YJA5_HUMAN
Cation channel sperm-associated pro...
CATSPERB
67Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_061634318F → Y. Corresponds to variant dbSNP:rs57706558Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0270081 – 478Missing in isoform 2. 1 PublicationAdd BLAST478

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK024360 mRNA Translation: BAB14896.1
BC126214 mRNA Translation: AAI26215.1
BC126216 mRNA Translation: AAI26217.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32142.1 [Q9H7T0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_079040.2, NM_024764.3 [Q9H7T0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000256343; ENSP00000256343; ENSG00000133962 [Q9H7T0-1]
ENST00000619027; ENSP00000478546; ENSG00000274338 [Q9H7T0-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79820

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79820

UCSC genome browser

More...
UCSCi
uc001xzs.2, human [Q9H7T0-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK024360 mRNA Translation: BAB14896.1
BC126214 mRNA Translation: AAI26215.1
BC126216 mRNA Translation: AAI26217.1
CCDSiCCDS32142.1 [Q9H7T0-1]
RefSeqiNP_079040.2, NM_024764.3 [Q9H7T0-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi122915, 1 interactor
STRINGi9606.ENSP00000256343

Protein family/group databases

TCDBi1.A.1.19.1, the voltage-gated ion channel (vic) superfamily

PTM databases

GlyGeniQ9H7T0, 5 sites
iPTMnetiQ9H7T0
PhosphoSitePlusiQ9H7T0

Genetic variation databases

BioMutaiCATSPERB
DMDMi158519875

Proteomic databases

EPDiQ9H7T0
jPOSTiQ9H7T0
MassIVEiQ9H7T0
PaxDbiQ9H7T0
PeptideAtlasiQ9H7T0
PRIDEiQ9H7T0
ProteomicsDBi81144 [Q9H7T0-1]
81145 [Q9H7T0-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
49510, 42 antibodies

The DNASU plasmid repository

More...
DNASUi
79820

Genome annotation databases

EnsembliENST00000256343; ENSP00000256343; ENSG00000133962 [Q9H7T0-1]
ENST00000619027; ENSP00000478546; ENSG00000274338 [Q9H7T0-1]
GeneIDi79820
KEGGihsa:79820
UCSCiuc001xzs.2, human [Q9H7T0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79820
DisGeNETi79820

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CATSPERB
HGNCiHGNC:20500, CATSPERB
HPAiENSG00000133962, Tissue enhanced (pancreas)
MIMi611169, gene
neXtProtiNX_Q9H7T0
OpenTargetsiENSG00000133962
PharmGKBiPA162381112
VEuPathDBiHostDB:ENSG00000133962

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QZ5S, Eukaryota
GeneTreeiENSGT00390000008198
HOGENOMiCLU_012454_0_0_1
InParanoidiQ9H7T0
OMAiKEPFLEW
PhylomeDBiQ9H7T0
TreeFamiTF328432

Enzyme and pathway databases

PathwayCommonsiQ9H7T0
ReactomeiR-HSA-1300642, Sperm Motility And Taxes

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
79820, 6 hits in 1012 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CATSPERB, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
79820
PharosiQ9H7T0, Tdark

Protein Ontology

More...
PROi
PR:Q9H7T0
RNActiQ9H7T0, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000133962, Expressed in body of pancreas and 111 other tissues
ExpressionAtlasiQ9H7T0, baseline and differential
GenevisibleiQ9H7T0, HS

Family and domain databases

InterProiView protein in InterPro
IPR028748, CATSPERB
PANTHERiPTHR14705, PTHR14705, 1 hit
PfamiView protein in Pfam
PF15149, CATSPERB, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCTSRB_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H7T0
Secondary accession number(s): A0AV51
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: July 24, 2007
Last modified: September 29, 2021
This is version 141 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again