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UniProtKB - Q9H7C9 (AAMDC_HUMAN)

Entry version 144 (25 May 2022)
Sequence version 1 (01 Mar 2001)
Previous versions | rss
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Protein

Mth938 domain-containing protein

Gene

AAMDC

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in preadipocyte differentiation and adipogenesis.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9H7C9

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9H7C9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mth938 domain-containing protein
Alternative name(s):
Adipogenesis associated Mth938 domain-containing protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AAMDC
Synonyms:C11orf67
ORF Names:PTD015
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:30205, AAMDC

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9H7C9

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000087884

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		28971

Open Targets

More...OpenTargetsi		ENSG00000087884

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA144596486

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9H7C9, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		AAMDC

Domain mapping of disease mutations (DMDM)

More...DMDMi		74733628

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002398141 – 122Mth938 domain-containing proteinAdd BLAST122

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9H7C9

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9H7C9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9H7C9

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9H7C9

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9H7C9

PeptideAtlas

More...PeptideAtlasi		Q9H7C9

PRoteomics IDEntifications database

More...PRIDEi		Q9H7C9

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		81102 [Q9H7C9-1]
81103 [Q9H7C9-2]
81104 [Q9H7C9-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9H7C9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9H7C9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000087884, Expressed in vastus lateralis and 238 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9H7C9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9H7C9, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000087884, Tissue enhanced (skeletal)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		118795, 32 interactors

Protein interaction database and analysis system

More...IntActi		Q9H7C9, 13 interactors

Molecular INTeraction database

More...MINTi		Q9H7C9

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000431808

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9H7C9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1122
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q9H7C9

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9H7C9

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q9H7C9

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni6 – 122MTH138-like domainBy similarityAdd BLAST117

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the AAMDC family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502S00Z, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000011958

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_074390_4_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9H7C9

Database of Orthologous Groups

More...OrthoDBi		1403160at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9H7C9

TreeFam database of animal gene trees

More...TreeFami		TF332083

Family and domain databases

Conserved Domains Database

More...CDDi		cd05126, Mth938, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.1230.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR034096, AAMDC
IPR036748, MTH938-like_sf
IPR007523, NDUFAF3/AAMDC

Pfam protein domain database

More...Pfami		View protein in Pfam
PF04430, DUF498, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF64076, SSF64076, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 7 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H7C9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTSPEIASLS WGQMKVKGSN TTYKDCKVWP GGSRTWDWRE TGTEHSPGVQ 
        60         70         80         90        100
PADVKEVVEK GVQTLVIGRG MSEALKVPSS TVEYLKKHGI DVRVLQTEQA 
       110        120 
VKEYNALVAQ GVRVGGVFHS TC
Length:122
Mass (Da):13,332
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA0C88AD311E62C78
GO
Isoform 2 (identifier: Q9H7C9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     77-118: VPSSTVEYLK...AQGVRVGGVF → APTQQLPSGV...TGAGLTSNML
     119-122: Missing.

Show »
Length:118
Mass (Da):12,807
Checksum:i15D644B69E9DFFDD
GO
Isoform 3 (identifier: Q9H7C9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     77-88: VPSSTVEYLKKH → DGIQGAQLDLNC
     89-122: Missing.

Show »
Length:88
Mass (Da):9,564
Checksum:i2522364F087D260B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K4DI89K4DI89_HUMAN
Mth938 domain-containing protein
AAMDC PTD015, hCG_27117
147Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PLK9E9PLK9_HUMAN
Mth938 domain-containing protein
AAMDC
137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PNP3E9PNP3_HUMAN
Mth938 domain-containing protein
AAMDC
141Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PR47E9PR47_HUMAN
Mth938 domain-containing protein
AAMDC
168Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PIQ4E9PIQ4_HUMAN
Mth938 domain-containing protein
AAMDC
90Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PJP1E9PJP1_HUMAN
Mth938 domain-containing protein
AAMDC
93Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YF35H0YF35_HUMAN
Mth938 domain-containing protein
AAMDC
51Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05269692V → M. Corresponds to variant dbSNP:rs2186564Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_01926777 – 118VPSST…VGGVF → APTQQLPSGVHVRAGVQFHL LQLHGTSFERCKTGAGLTSN ML in isoform 2. 1 PublicationAdd BLAST42
Alternative sequenceiVSP_01926677 – 88VPSST…YLKKH → DGIQGAQLDLNC in isoform 3. 1 PublicationAdd BLAST12
Alternative sequenceiVSP_01926889 – 122Missing in isoform 3. 1 PublicationAdd BLAST34
Alternative sequenceiVSP_019269119 – 122Missing in isoform 2. 1 Publication4

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF092136 mRNA Translation: AAD40378.1
AK024688 mRNA Translation: BAB14963.1
CR457332 mRNA Translation: CAG33613.1
AP000580 Genomic DNA No translation available.
AP002812 Genomic DNA No translation available.
BC002752 mRNA Translation: AAH02752.1
BC016854 mRNA Translation: AAH16854.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS8254.1 [Q9H7C9-1]
CCDS86232.1 [Q9H7C9-1]

NCBI Reference Sequences

More...RefSeqi		NP_001303886.1, NM_001316957.1
NP_001303889.1, NM_001316960.1 [Q9H7C9-1]
NP_001303890.1, NM_001316961.1 [Q9H7C9-1]
NP_001303891.1, NM_001316962.1 [Q9H7C9-1]
NP_078960.1, NM_024684.3 [Q9H7C9-1]
XP_011543271.1, XM_011544969.2 [Q9H7C9-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000393427.7; ENSP00000377078.2; ENSG00000087884.15
ENST00000526415.5; ENSP00000431808.1; ENSG00000087884.15
ENST00000532481.5; ENSP00000433293.1; ENSG00000087884.15 [Q9H7C9-3]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		28971

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:28971

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000393427.7; ENSP00000377078.2; NM_024684.4; NP_078960.1

UCSC genome browser

More...UCSCi		uc001oyp.4, human [Q9H7C9-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF092136 mRNA Translation: AAD40378.1
AK024688 mRNA Translation: BAB14963.1
CR457332 mRNA Translation: CAG33613.1
AP000580 Genomic DNA No translation available.
AP002812 Genomic DNA No translation available.
BC002752 mRNA Translation: AAH02752.1
BC016854 mRNA Translation: AAH16854.1
CCDSiCCDS8254.1 [Q9H7C9-1]
CCDS86232.1 [Q9H7C9-1]
RefSeqiNP_001303886.1, NM_001316957.1
NP_001303889.1, NM_001316960.1 [Q9H7C9-1]
NP_001303890.1, NM_001316961.1 [Q9H7C9-1]
NP_001303891.1, NM_001316962.1 [Q9H7C9-1]
NP_078960.1, NM_024684.3 [Q9H7C9-1]
XP_011543271.1, XM_011544969.2 [Q9H7C9-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2AB1X-ray2.59A/B2-122[»]
2Q4QX-ray2.59A/B2-122[»]
AlphaFoldDBiQ9H7C9
SMRiQ9H7C9
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi118795, 32 interactors
IntActiQ9H7C9, 13 interactors
MINTiQ9H7C9
STRINGi9606.ENSP00000431808

PTM databases

iPTMnetiQ9H7C9
PhosphoSitePlusiQ9H7C9

Genetic variation databases

BioMutaiAAMDC
DMDMi74733628

Proteomic databases

EPDiQ9H7C9
jPOSTiQ9H7C9
MassIVEiQ9H7C9
MaxQBiQ9H7C9
PaxDbiQ9H7C9
PeptideAtlasiQ9H7C9
PRIDEiQ9H7C9
ProteomicsDBi81102 [Q9H7C9-1]
81103 [Q9H7C9-2]
81104 [Q9H7C9-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		31275, 160 antibodies from 19 providers

The DNASU plasmid repository

More...DNASUi		28971

Genome annotation databases

EnsembliENST00000393427.7; ENSP00000377078.2; ENSG00000087884.15
ENST00000526415.5; ENSP00000431808.1; ENSG00000087884.15
ENST00000532481.5; ENSP00000433293.1; ENSG00000087884.15 [Q9H7C9-3]
GeneIDi28971
KEGGihsa:28971
MANE-SelectiENST00000393427.7; ENSP00000377078.2; NM_024684.4; NP_078960.1
UCSCiuc001oyp.4, human [Q9H7C9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		28971
DisGeNETi28971

GeneCards: human genes, protein and diseases

More...GeneCardsi		AAMDC
HGNCiHGNC:30205, AAMDC
HPAiENSG00000087884, Tissue enhanced (skeletal)
neXtProtiNX_Q9H7C9
OpenTargetsiENSG00000087884
PharmGKBiPA144596486
VEuPathDBiHostDB:ENSG00000087884

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502S00Z, Eukaryota
GeneTreeiENSGT00390000011958
HOGENOMiCLU_074390_4_0_1
InParanoidiQ9H7C9
OrthoDBi1403160at2759
PhylomeDBiQ9H7C9
TreeFamiTF332083

Enzyme and pathway databases

PathwayCommonsiQ9H7C9
SignaLinkiQ9H7C9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		28971, 16 hits in 1080 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		AAMDC, human
EvolutionaryTraceiQ9H7C9

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		28971
PharosiQ9H7C9, Tdark

Protein Ontology

More...PROi		PR:Q9H7C9
RNActiQ9H7C9, protein

Gene expression databases

BgeeiENSG00000087884, Expressed in vastus lateralis and 238 other tissues
ExpressionAtlasiQ9H7C9, baseline and differential
GenevisibleiQ9H7C9, HS

Family and domain databases

CDDicd05126, Mth938, 1 hit
Gene3Di3.40.1230.10, 1 hit
InterProiView protein in InterPro
IPR034096, AAMDC
IPR036748, MTH938-like_sf
IPR007523, NDUFAF3/AAMDC
PfamiView protein in Pfam
PF04430, DUF498, 1 hit
SUPFAMiSSF64076, SSF64076, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAAMDC_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H7C9
Secondary accession number(s): Q96AQ4, Q9Y6B1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: March 1, 2001
Last modified: May 25, 2022
This is version 144 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  2. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  3. Human entries with genetic variants
    List of human entries with genetic variants
  4. Human variants curated from literature reports
    Index of human variants curated from literature reports
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families
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