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Entry version 125 (18 Sep 2019)
Sequence version 1 (01 Mar 2001)
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Protein

Lipid droplet-associated hydrolase

Gene

LDAH

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Serine lipid hydrolase associated with lipid droplets. Highly expressed in macrophage-rich areas in atherosclerotic lesions, suggesting that it could promote cholesterol ester turnover in macrophages.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei139NucleophilePROSITE-ProRule annotation1
Active sitei271Charge relay systemCurated1
Active sitei300Charge relay systemCurated1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
Biological processLipid degradation, Lipid metabolism

Protein family/group databases

ESTHER database of the Alpha/Beta-hydrolase fold superfamily of proteins

More...
ESTHERi
human-LDAH LIDHydrolase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Lipid droplet-associated hydrolaseImported (EC:3.1.1.-By similarity)
Alternative name(s):
Lipid droplet-associated serine hydrolase1 Publication
Short name:
hLDAH1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LDAH1 PublicationImported
Synonyms:C2orf43Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26145 LDAH

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
613570 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H6V9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum, Lipid droplet

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
60526

Open Targets

More...
OpenTargetsi
ENSG00000118961

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA147358698

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9H6V9

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
LDAH

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74761484

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003001241 – 325Lipid droplet-associated hydrolaseAdd BLAST325

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H6V9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H6V9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9H6V9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H6V9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H6V9

PeptideAtlas

More...
PeptideAtlasi
Q9H6V9

PRoteomics IDEntifications database

More...
PRIDEi
Q9H6V9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
7054
7068
81044 [Q9H6V9-1]
81045 [Q9H6V9-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H6V9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H6V9

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9H6V9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Present in macrophage-rich areas in atherosclerotic lesionsv(at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000118961 Expressed in 194 organ(s), highest expression level in adrenal tissue

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9H6V9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H6V9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA034729
HPA034730

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000237822

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the AB hydrolase superfamily. LDAH family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3975 Eukaryota
ENOG410ZTV7 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000009688

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000045737

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H6V9

Database of Orthologous Groups

More...
OrthoDBi
1163030at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H6V9

TreeFam database of animal gene trees

More...
TreeFami
TF313050

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.1820, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029058 AB_hydrolase
IPR019363 LDAH

The PANTHER Classification System

More...
PANTHERi
PTHR13390 PTHR13390, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10230 LIDHydrolase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53474 SSF53474, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00120 LIPASE_SER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 8 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H6V9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDSELKEEIP VHEEFILCGG AETQVLKCGP WTDLFHDQSV KRPKLLIFII
60 70 80 90 100
PGNPGFSAFY VPFAKALYSL TNRRFPVWTI SHAGHALAPK DKKILTTSED
110 120 130 140 150
SNAQEIKDIY GLNGQIEHKL AFLRTHVPKD MKLVLIGHSI GSYFTLQMLK
160 170 180 190 200
RVPELPVIRA FLLFPTIERM SESPNGRIAT PLLCWFRYVL YVTGYLLLKP
210 220 230 240 250
CPETIKSLLI RRGLQVMNLE NEFSPLNILE PFCLANAAYL GGQEMMEVVK
260 270 280 290 300
RDDETIKEHL CKLTFYYGTI DPWCPKEYYE DIKKDFPEGD IRLCEKNIPH
310 320
AFITHFNQEM ADMIADSLKD DLSKM
Length:325
Mass (Da):37,319
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6D5B414E60028DD1
GO
Isoform 2 (identifier: Q9H6V9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     51-51: P → PGERKSL

Show »
Length:331
Mass (Da):37,989
Checksum:iA1D4C6BC84EB8A08
GO
Isoform 3 (identifier: Q9H6V9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     52-99: Missing.

Note: No experimental confirmation available.
Show »
Length:277
Mass (Da):32,029
Checksum:iAF22651FB1A42F49
GO
Isoform 4 (identifier: Q9H6V9-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-130: Missing.

Note: No experimental confirmation available.
Show »
Length:195
Mass (Da):22,663
Checksum:i285B7E69BFAA6714
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B4DRG3B4DRG3_HUMAN
Lipid droplet-associated hydrolase
LDAH FLJ21820, hCG_32091
166Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B5MDU6B5MDU6_HUMAN
Lipid droplet-associated hydrolase
LDAH
370Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MSH6A0A0A0MSH6_HUMAN
Lipid droplet-associated hydrolase
LDAH
283Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B5MCE2B5MCE2_HUMAN
Lipid droplet-associated hydrolase
LDAH
146Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JUM0C9JUM0_HUMAN
Lipid droplet-associated hydrolase
LDAH
159Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YTH1D3YTH1_HUMAN
Lipid droplet-associated hydrolase
LDAH
156Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B5MCU4B5MCU4_HUMAN
Lipid droplet-associated hydrolase
LDAH
240Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JHU6C9JHU6_HUMAN
Lipid droplet-associated hydrolase
LDAH
130Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0552831 – 130Missing in isoform 4. 1 PublicationAdd BLAST130
Alternative sequenceiVSP_04220251P → PGERKSL in isoform 2. 1 Publication1
Alternative sequenceiVSP_05462452 – 99Missing in isoform 3. 1 PublicationAdd BLAST48

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK025473 mRNA Translation: BAB15142.1
AK316162 mRNA Translation: BAH14533.1
AK316204 mRNA Translation: BAH14575.1
AK316310 mRNA Translation: BAH14681.1
DC325170 mRNA No translation available.
AC012361 Genomic DNA Translation: AAY14959.1
AC012065 Genomic DNA Translation: AAX93236.1
CH471053 Genomic DNA Translation: EAX00809.1
CH471053 Genomic DNA Translation: EAX00810.1
BC017473 mRNA Translation: AAH17473.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1702.1 [Q9H6V9-1]
CCDS62864.1 [Q9H6V9-4]
CCDS62865.1 [Q9H6V9-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001269649.1, NM_001282720.1 [Q9H6V9-3]
NP_001269650.1, NM_001282721.1 [Q9H6V9-4]
NP_001269651.1, NM_001282722.1 [Q9H6V9-4]
NP_068744.1, NM_021925.3 [Q9H6V9-1]
XP_011531316.1, XM_011533014.2 [Q9H6V9-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000237822; ENSP00000237822; ENSG00000118961 [Q9H6V9-1]
ENST00000541941; ENSP00000440570; ENSG00000118961 [Q9H6V9-4]
ENST00000619656; ENSP00000483067; ENSG00000118961 [Q9H6V9-4]
ENST00000626491; ENSP00000487592; ENSG00000118961 [Q9H6V9-3]

Database of genes from NCBI RefSeq genomes

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GeneIDi
60526

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:60526

UCSC genome browser

More...
UCSCi
uc002rec.5 human [Q9H6V9-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK025473 mRNA Translation: BAB15142.1
AK316162 mRNA Translation: BAH14533.1
AK316204 mRNA Translation: BAH14575.1
AK316310 mRNA Translation: BAH14681.1
DC325170 mRNA No translation available.
AC012361 Genomic DNA Translation: AAY14959.1
AC012065 Genomic DNA Translation: AAX93236.1
CH471053 Genomic DNA Translation: EAX00809.1
CH471053 Genomic DNA Translation: EAX00810.1
BC017473 mRNA Translation: AAH17473.1
CCDSiCCDS1702.1 [Q9H6V9-1]
CCDS62864.1 [Q9H6V9-4]
CCDS62865.1 [Q9H6V9-3]
RefSeqiNP_001269649.1, NM_001282720.1 [Q9H6V9-3]
NP_001269650.1, NM_001282721.1 [Q9H6V9-4]
NP_001269651.1, NM_001282722.1 [Q9H6V9-4]
NP_068744.1, NM_021925.3 [Q9H6V9-1]
XP_011531316.1, XM_011533014.2 [Q9H6V9-2]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9606.ENSP00000237822

Protein family/group databases

ESTHERihuman-LDAH LIDHydrolase

PTM databases

iPTMnetiQ9H6V9
PhosphoSitePlusiQ9H6V9
SwissPalmiQ9H6V9

Polymorphism and mutation databases

BioMutaiLDAH
DMDMi74761484

Proteomic databases

EPDiQ9H6V9
jPOSTiQ9H6V9
MassIVEiQ9H6V9
MaxQBiQ9H6V9
PaxDbiQ9H6V9
PeptideAtlasiQ9H6V9
PRIDEiQ9H6V9
ProteomicsDBi7054
7068
81044 [Q9H6V9-1]
81045 [Q9H6V9-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
60526

Genome annotation databases

EnsembliENST00000237822; ENSP00000237822; ENSG00000118961 [Q9H6V9-1]
ENST00000541941; ENSP00000440570; ENSG00000118961 [Q9H6V9-4]
ENST00000619656; ENSP00000483067; ENSG00000118961 [Q9H6V9-4]
ENST00000626491; ENSP00000487592; ENSG00000118961 [Q9H6V9-3]
GeneIDi60526
KEGGihsa:60526
UCSCiuc002rec.5 human [Q9H6V9-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
60526
DisGeNETi60526

GeneCards: human genes, protein and diseases

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GeneCardsi
LDAH
HGNCiHGNC:26145 LDAH
HPAiHPA034729
HPA034730
MIMi613570 gene
neXtProtiNX_Q9H6V9
OpenTargetsiENSG00000118961
PharmGKBiPA147358698

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG3975 Eukaryota
ENOG410ZTV7 LUCA
GeneTreeiENSGT00390000009688
HOGENOMiHOG000045737
InParanoidiQ9H6V9
OrthoDBi1163030at2759
PhylomeDBiQ9H6V9
TreeFamiTF313050

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
LDAH human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
60526
PharosiQ9H6V9

Protein Ontology

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PROi
PR:Q9H6V9

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000118961 Expressed in 194 organ(s), highest expression level in adrenal tissue
ExpressionAtlasiQ9H6V9 baseline and differential
GenevisibleiQ9H6V9 HS

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR019363 LDAH
PANTHERiPTHR13390 PTHR13390, 1 hit
PfamiView protein in Pfam
PF10230 LIDHydrolase, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit
PROSITEiView protein in PROSITE
PS00120 LIPASE_SER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLDAH_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H6V9
Secondary accession number(s): B7ZA47
, B7ZAJ5, D6W530, E7ESN0, Q53T37, Q53T58
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2001
Last modified: September 18, 2019
This is version 125 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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