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Protein

WD repeat and coiled-coil-containing protein

Gene

WDCP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • kinase binding Source: UniProtKB

GO - Biological processi

  • protein complex oligomerization Source: UniProtKB

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
WD repeat and coiled-coil-containing proteinCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:WDCPImported
Synonyms:C2orf44
ORF Names:PP384
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000163026.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26157 WDCP

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
616234 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H6R7

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

A chromosomal aberration involving WDCP is found in one subject with colorectal cancer. Translocation t(2;2)(p23.3;p23.1). A 5 million base pair tandem duplication generates an in-frame WDCP-ALK gene fusion.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi540P → A: Loss of interaction with HCK; when associated with P-543. 1 Publication1
Mutagenesisi543P → A: Loss of interaction with HCK; when associated with P-543. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
80304

Open Targets

More...
OpenTargetsi
ENSG00000163026

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA147358716

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C2orf44

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74752699

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002995011 – 721WD repeat and coiled-coil-containing proteinAdd BLAST721

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei299PhosphoserineCombined sources1
Modified residuei468PhosphoserineCombined sources1
Modified residuei501PhosphoserineCombined sources1
Modified residuei523PhosphoserineCombined sources1
Modified residuei530PhosphothreonineCombined sources1
Modified residuei686PhosphoserineCombined sources1
Modified residuei690PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated on Tyr when associated with HCK.1 Publication

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q9H6R7

MaxQB - The MaxQuant DataBase

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MaxQBi
Q9H6R7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H6R7

PeptideAtlas

More...
PeptideAtlasi
Q9H6R7

PRoteomics IDEntifications database

More...
PRIDEi
Q9H6R7

ProteomicsDB human proteome resource

More...
ProteomicsDBi
81022
81023 [Q9H6R7-2]
81024 [Q9H6R7-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H6R7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H6R7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000163026 Expressed in 142 organ(s), highest expression level in female gonad

CleanEx database of gene expression profiles

More...
CleanExi
HS_C2orf44

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9H6R7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H6R7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA041054

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Oligomer. Interacts with HCK (via SH3 domain).2 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123217, 53 interactors

Protein interaction database and analysis system

More...
IntActi
Q9H6R7, 34 interactors

Molecular INTeraction database

More...
MINTi
Q9H6R7

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000295148

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9H6R7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati55 – 98WD 1Add BLAST44
Repeati154 – 194WD 2Add BLAST41

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni539 – 545Interaction with HCK1 Publication7

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili556 – 584Sequence analysisAdd BLAST29

Keywords - Domaini

Coiled coil, Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJSA Eukaryota
ENOG410YM0Q LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001660

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000111320

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG055062

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H6R7

Identification of Orthologs from Complete Genome Data

More...
OMAi
CNGKLRL

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0Q4H

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H6R7

TreeFam database of animal gene trees

More...
TreeFami
TF333528

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028041 WDCP

The PANTHER Classification System

More...
PANTHERi
PTHR14897 PTHR14897, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15390 WDCP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H6R7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MELGKGKLLR TGLNALHQAV HPIHGLAWTD GNQVVLTDLR LHSGEVKFGD
60 70 80 90 100
SKVIGQFECV CGLSWAPPVA DDTPVLLAVQ HEKHVTVWQL CPSPMESSKW
110 120 130 140 150
LTSQTCEIRG SLPILPQGCV WHPKCAILTV LTAQDVSIFP NVHSDDSQVK
160 170 180 190 200
ADINTQGRIH CACWTQDGLR LVVAVGSSLH SYIWDSAQKT LHRCSSCLVF
210 220 230 240 250
DVDSHVCSIT ATVDSQVAIA TELPLDKICG LNASETFNIP PNSKDMTPYA
260 270 280 290 300
LPVIGEVRSM DKEATDSETN SEVSVSSSYL EPLDLTHIHF NQHKSEGNSL
310 320 330 340 350
ICLRKKDYLT GTGQDSSHLV LVTFKKAVTM TRKVTIPGIL VPDLIAFNLK
360 370 380 390 400
AHVVAVASNT CNIILIYSVI PSSVPNIQQI RLENTERPKG ICFLTDQLLL
410 420 430 440 450
ILVGKQKLTD TTFLPSSKSD QYAISLIVRE IMLEEEPSIT SGESQTTYST
460 470 480 490 500
FSAPLNKANR KKLIESLSPD FCHQNKGLLL TVNTSSQNGR PGRTLIKEIQ
510 520 530 540 550
SPLSSICDGS IALDAEPVTQ PASLPRHSST PDHTSTLEPP RLPQRKNLQS
560 570 580 590 600
EKETYQLSKE VEILSRNLVE MQRCLSELTN RLHNGKKSSS VYPLSQDLPY
610 620 630 640 650
VHIIYQKPYY LGPVVEKRAV LLCDGKLRLS TVQQTFGLSL IEMLHDSHWI
660 670 680 690 700
LLSADSEGFI PLTFTATQEI IIRDGSLSRS DVFRDSFSHS PGAVSSLKVF
710 720
TGLAAPSLDT TGCCNHVDGM A
Length:721
Mass (Da):79,136
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4A4164C81A693DAE
GO
Isoform 2 (identifier: Q9H6R7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     607-622: KPYYLGPVVEKRAVLL → IPTGFFSLLTVRALSR
     623-721: Missing.

Note: No experimental confirmation available.
Show »
Length:622
Mass (Da):68,456
Checksum:i04657B17D5096FD0
GO
Isoform 3 (identifier: Q9H6R7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-487: Missing.
     488-488: N → M

Note: No experimental confirmation available.
Show »
Length:234
Mass (Da):25,845
Checksum:iD06EAF3E6B5A9073
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JYC1C9JYC1_HUMAN
WD repeat and coiled-coil-containin...
WDCP
174Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_034834102T → M. Corresponds to variant dbSNP:rs3731620Ensembl.1
Natural variantiVAR_035876454P → S in a breast cancer sample; somatic mutation. 1 Publication1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0277121 – 487Missing in isoform 3. 1 PublicationAdd BLAST487
Alternative sequenceiVSP_027715488N → M in isoform 3. 1 Publication1
Alternative sequenceiVSP_027713607 – 622KPYYL…RAVLL → IPTGFFSLLTVRALSR in isoform 2. 1 PublicationAdd BLAST16
Alternative sequenceiVSP_027714623 – 721Missing in isoform 2. 1 PublicationAdd BLAST99

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF218013 mRNA Translation: AAG17255.1
AK025598 mRNA Translation: BAB15186.1
AC104665 Genomic DNA Translation: AAY24115.1
CH471053 Genomic DNA Translation: EAX00771.1
CH471053 Genomic DNA Translation: EAX00772.1
BC035698 mRNA Translation: AAH35698.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1705.1 [Q9H6R7-1]
CCDS46229.1 [Q9H6R7-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001135791.1, NM_001142319.1 [Q9H6R7-2]
NP_079479.1, NM_025203.2 [Q9H6R7-1]

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.24624

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000295148; ENSP00000295148; ENSG00000163026 [Q9H6R7-1]
ENST00000406895; ENSP00000385816; ENSG00000163026 [Q9H6R7-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80304

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:80304

UCSC genome browser

More...
UCSCi
uc002rep.3 human [Q9H6R7-1]

Keywords - Coding sequence diversityi

Alternative splicing, Chromosomal rearrangement, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF218013 mRNA Translation: AAG17255.1
AK025598 mRNA Translation: BAB15186.1
AC104665 Genomic DNA Translation: AAY24115.1
CH471053 Genomic DNA Translation: EAX00771.1
CH471053 Genomic DNA Translation: EAX00772.1
BC035698 mRNA Translation: AAH35698.1
CCDSiCCDS1705.1 [Q9H6R7-1]
CCDS46229.1 [Q9H6R7-2]
RefSeqiNP_001135791.1, NM_001142319.1 [Q9H6R7-2]
NP_079479.1, NM_025203.2 [Q9H6R7-1]
UniGeneiHs.24624

3D structure databases

ProteinModelPortaliQ9H6R7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123217, 53 interactors
IntActiQ9H6R7, 34 interactors
MINTiQ9H6R7
STRINGi9606.ENSP00000295148

PTM databases

iPTMnetiQ9H6R7
PhosphoSitePlusiQ9H6R7

Polymorphism and mutation databases

BioMutaiC2orf44
DMDMi74752699

Proteomic databases

EPDiQ9H6R7
MaxQBiQ9H6R7
PaxDbiQ9H6R7
PeptideAtlasiQ9H6R7
PRIDEiQ9H6R7
ProteomicsDBi81022
81023 [Q9H6R7-2]
81024 [Q9H6R7-3]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000295148; ENSP00000295148; ENSG00000163026 [Q9H6R7-1]
ENST00000406895; ENSP00000385816; ENSG00000163026 [Q9H6R7-2]
GeneIDi80304
KEGGihsa:80304
UCSCiuc002rep.3 human [Q9H6R7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80304
DisGeNETi80304
EuPathDBiHostDB:ENSG00000163026.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
WDCP

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0001870
HGNCiHGNC:26157 WDCP
HPAiHPA041054
MIMi616234 gene
neXtProtiNX_Q9H6R7
OpenTargetsiENSG00000163026
PharmGKBiPA147358716

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IJSA Eukaryota
ENOG410YM0Q LUCA
GeneTreeiENSGT00390000001660
HOGENOMiHOG000111320
HOVERGENiHBG055062
InParanoidiQ9H6R7
OMAiCNGKLRL
OrthoDBiEOG091G0Q4H
PhylomeDBiQ9H6R7
TreeFamiTF333528

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
80304

Protein Ontology

More...
PROi
PR:Q9H6R7

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000163026 Expressed in 142 organ(s), highest expression level in female gonad
CleanExiHS_C2orf44
ExpressionAtlasiQ9H6R7 baseline and differential
GenevisibleiQ9H6R7 HS

Family and domain databases

InterProiView protein in InterPro
IPR028041 WDCP
PANTHERiPTHR14897 PTHR14897, 1 hit
PfamiView protein in Pfam
PF15390 WDCP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiWDCP_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H6R7
Secondary accession number(s): D6W532, Q8IYK0, Q9HBP5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2001
Last modified: December 5, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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