Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - Q9H5H4 (ZN768_HUMAN)

Entry version 165 (07 Apr 2021)
Sequence version 2 (11 Sep 2007)
Previous versions | rss
Add a publicationFeedback
Protein

Zinc finger protein 768

Gene

ZNF768

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri261 – 283C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri289 – 311C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri317 – 339C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri345 – 367C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri373 – 395C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri401 – 423C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri429 – 451C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri457 – 479C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri485 – 507C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri513 – 535C2H2-type 10PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9H5H4

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 768
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF768
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:26273, ZNF768

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		618032, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9H5H4

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000169957.9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000169957

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162410327

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9H5H4, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF768

Domain mapping of disease mutations (DMDM)

More...DMDMi		158564024

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003044081 – 540Zinc finger protein 768Add BLAST540

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei17PhosphoserineCombined sources1
Modified residuei23PhosphoserineBy similarity1
Modified residuei33PhosphoserineBy similarity1
Modified residuei83PhosphoserineCombined sources1
Modified residuei90PhosphoserineCombined sources1
Modified residuei97PhosphoserineCombined sources1
Modified residuei104PhosphoserineBy similarity1
Modified residuei125PhosphoserineCombined sources1
Modified residuei132PhosphoserineCombined sources1
Modified residuei139PhosphoserineCombined sources1
Modified residuei160PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9H5H4

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9H5H4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9H5H4

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9H5H4

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9H5H4

PeptideAtlas

More...PeptideAtlasi		Q9H5H4

PRoteomics IDEntifications database

More...PRIDEi		Q9H5H4

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		80905

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9H5H4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9H5H4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000169957, Expressed in apex of heart and 239 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9H5H4, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9H5H4, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000169957, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		122839, 58 interactors

Protein interaction database and analysis system

More...IntActi		Q9H5H4, 29 interactors

Molecular INTeraction database

More...MINTi		Q9H5H4

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000369777

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9H5H4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9H5H4

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi34 – 39Poly-Glu6
Compositional biasi55 – 140Pro-richAdd BLAST86

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri261 – 283C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri289 – 311C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri317 – 339C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri345 – 367C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri373 – 395C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri401 – 423C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri429 – 451C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri457 – 479C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri485 – 507C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri513 – 535C2H2-type 10PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000162267

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9H5H4

Identification of Orthologs from Complete Genome Data

More...OMAi		FEPQNPE

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9H5H4

TreeFam database of animal gene trees

More...TreeFami		TF350793

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000684, RNA_pol_II_repeat_euk
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF05001, RNA_pol_Rpb1_R, 4 hits
PF00096, zf-C2H2, 10 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355, ZnF_C2H2, 10 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 6 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9H5H4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEREALPWGL EPQDVQSSDE MRSPEGYLRG NMSENEEEEI SQQEGSGDYE 
        60         70         80         90        100
VEEIPFGLEP QSPGFEPQSP EFEPQSPRFE PESPGFESRS PGLVPPSPEF 
       110        120        130        140        150
APRSPESDSQ SPEFESQSPR YEPQSPGYEP RSPGYEPRSP GYESESSRYE 
       160        170        180        190        200
SQNTELKTQS PEFEAQSSKF QEGAEMLLNP EEKSPLNISV GVHPLDSFTQ 
       210        220        230        240        250
GFGEQPTGDL PIGPPFEMPT GALLSTPQFE MLQNPLGLTG ALRGPGRRGG 
       260        270        280        290        300
RARGGQGPRP NICGICGKSF GRGSTLIQHQ RIHTGEKPYK CEVCSKAFSQ 
       310        320        330        340        350
SSDLIKHQRT HTGERPYKCP RCGKAFADSS YLLRHQRTHS GQKPYKCPHC 
       360        370        380        390        400
GKAFGDSSYL LRHQRTHSHE RPYSCTECGK CYSQNSSLRS HQRVHTGQRP 
       410        420        430        440        450
FSCGICGKSF SQRSALIPHA RSHAREKPFK CPECGKRFGQ SSVLAIHART 
       460        470        480        490        500
HLPGRTYSCP DCGKTFNRSS TLIQHQRSHT GERPYRCAVC GKGFCRSSTL 
       510        520        530        540
LQHHRVHSGE RPYKCDDCGK AFSQSSDLIR HQRTHAAGRR
Length:540
Mass (Da):60,229
Last modified:September 11, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7E9299F7C1BEE866
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BS42H3BS42_HUMAN
Zinc finger protein 768
ZNF768
509Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH13760 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH92403 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAB15652 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_035024181E → D1 PublicationCorresponds to variant dbSNP:rs10871453Ensembl.1
Natural variantiVAR_052900488A → S. Corresponds to variant dbSNP:rs3751848Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BC013760 mRNA Translation: AAH13760.1 Different initiation.
BC092403 mRNA Translation: AAH92403.2 Different initiation.
AK027089 mRNA Translation: BAB15652.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS10681.2

NCBI Reference Sequences

More...RefSeqi		NP_078947.3, NM_024671.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000380412; ENSP00000369777; ENSG00000169957

Database of genes from NCBI RefSeq genomes

More...GeneIDi		79724

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:79724

UCSC genome browser

More...UCSCi		uc002dyk.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC013760 mRNA Translation: AAH13760.1 Different initiation.
BC092403 mRNA Translation: AAH92403.2 Different initiation.
AK027089 mRNA Translation: BAB15652.1 Different initiation.
CCDSiCCDS10681.2
RefSeqiNP_078947.3, NM_024671.3

3D structure databases

SMRiQ9H5H4
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi122839, 58 interactors
IntActiQ9H5H4, 29 interactors
MINTiQ9H5H4
STRINGi9606.ENSP00000369777

PTM databases

iPTMnetiQ9H5H4
PhosphoSitePlusiQ9H5H4

Genetic variation databases

BioMutaiZNF768
DMDMi158564024

Proteomic databases

EPDiQ9H5H4
jPOSTiQ9H5H4
MassIVEiQ9H5H4
MaxQBiQ9H5H4
PaxDbiQ9H5H4
PeptideAtlasiQ9H5H4
PRIDEiQ9H5H4
ProteomicsDBi80905

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		13715, 131 antibodies

Genome annotation databases

EnsembliENST00000380412; ENSP00000369777; ENSG00000169957
GeneIDi79724
KEGGihsa:79724
UCSCiuc002dyk.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79724

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF768
HGNCiHGNC:26273, ZNF768
HPAiENSG00000169957, Low tissue specificity
MIMi618032, gene
neXtProtiNX_Q9H5H4
OpenTargetsiENSG00000169957
PharmGKBiPA162410327
VEuPathDBiHostDB:ENSG00000169957.9

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000162267
InParanoidiQ9H5H4
OMAiFEPQNPE
OrthoDBi1318335at2759
PhylomeDBiQ9H5H4
TreeFamiTF350793

Enzyme and pathway databases

PathwayCommonsiQ9H5H4

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		79724, 4 hits in 1018 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZNF768, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		79724
PharosiQ9H5H4, Tdark

Protein Ontology

More...PROi		PR:Q9H5H4
RNActiQ9H5H4, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000169957, Expressed in apex of heart and 239 other tissues
ExpressionAtlasiQ9H5H4, baseline and differential
GenevisibleiQ9H5H4, HS

Family and domain databases

InterProiView protein in InterPro
IPR000684, RNA_pol_II_repeat_euk
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF05001, RNA_pol_Rpb1_R, 4 hits
PF00096, zf-C2H2, 10 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 10 hits
SUPFAMiSSF57667, SSF57667, 6 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN768_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H5H4
Secondary accession number(s): Q569L7, Q96CX4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 11, 2007
Last modified: April 7, 2021
This is version 165 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again