UniProtKB - Q9H579 (MROH8_HUMAN)
Protein
Protein MROH8
Gene
MROH8
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Protein MROH8Alternative name(s): Maestro heat-like repeat-containing protein family member 8 |
Gene namesi | Name:MROH8 Synonyms:C20orf131, C20orf132 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:16125, MROH8 |
neXtProti | NX_Q9H579 |
VEuPathDBi | HostDB:ENSG00000101353.14 |
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 140699 |
PharmGKBi | PA25674 |
Miscellaneous databases
Pharosi | Q9H579, Tdark |
Genetic variation databases
BioMutai | MROH8 |
DMDMi | 28201794 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000079462 | 1 – 483 | Protein MROH8Add BLAST | 483 |
Proteomic databases
MassIVEi | Q9H579 |
PeptideAtlasi | Q9H579 |
PRIDEi | Q9H579 |
ProteomicsDBi | 80895 [Q9H579-1] 80896 [Q9H579-2] |
PTM databases
iPTMneti | Q9H579 |
Expressioni
Gene expression databases
Bgeei | ENSG00000101353, Expressed in testis and 149 other tissues |
ExpressionAtlasi | Q9H579, baseline and differential |
Genevisiblei | Q9H579, HS |
Organism-specific databases
HPAi | ENSG00000101353, Tissue enhanced (testis) |
Interactioni
Protein-protein interaction databases
BioGRIDi | 126660, 4 interactors |
STRINGi | 9606.ENSP00000339971 |
Miscellaneous databases
RNActi | Q9H579, protein |
Family & Domainsi
Phylogenomic databases
eggNOGi | KOG2032, Eukaryota |
InParanoidi | Q9H579 |
OMAi | RMKGTDW |
OrthoDBi | 31329at2759 |
PhylomeDBi | Q9H579 |
Family and domain databases
InterProi | View protein in InterPro IPR016024, ARM-type_fold |
SUPFAMi | SSF48371, SSF48371, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q9H579-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MSSKHRICSQ EEVVIPCAYD SDSESVDLEL SNLEIIKKGS SSIELTDLDI
60 70 80 90 100
PDIPGLHCEP LSHSPRHLTQ QDPLSEAIVE KLIQSIQKVF NGELKGELEK
110 120 130 140 150
LKFLGDLSSL SQALPYDETA KSFIHSHIAD IVHTLNVLVQ EERPHSLSSS
160 170 180 190 200
MRQEVFVTIA DLSYQDVHLL LGSEDRAELF SLTIKSIITL PSVRTLTQIQ
210 220 230 240 250
EIMPNGTCNT ECLYRQTFQA FSEMLQSLVV KDPHLENLDT IIKLPLRFQR
260 270 280 290 300
LGHLVALMAL LCGDPQEKVA EEAAEGIHSL LHITLRLKYI THDKKDQQNL
310 320 330 340 350
KRALTKCREF LELHSSAAKC FYNCPFRIAQ VFEGFLDSNE LCQFIMTTFD
360 370 380 390 400
TLKTLKHPCI QRSAGELLLT LAKNTESQFE KVPEIMGVIC AQLSIISQPR
410 420 430 440 450
VRQQIINTVS LFISRPKYTD IVLSFLLCHP VPYNRHLAEV WRMLSVELPS
460 470 480
TTWILWRLLR KLQKCHNEPA QEKMAYVAVA VSP
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketH0Y7Y5 | H0Y7Y5_HUMAN | Protein MROH8 | MROH8 | 670 | Annotation score: | ||
Q5JYQ9 | Q5JYQ9_HUMAN | Protein MROH8 | MROH8 | 24 | Annotation score: |
Sequence cautioni
The sequence BAC04162 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 354 | T → N in BAC04162 (PubMed:14702039).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_003821 | 331 – 381 | Missing in isoform 2. 1 PublicationAdd BLAST | 51 | |
Alternative sequenceiVSP_003822 | 481 – 483 | VSP → ATDALYEVFLGNRLRAATFR LFPQLLMTLLIQIHHSIGLT MSDVDIPSGLYTEQEVPSEV TPLCFAMQATKTLLLRTCCL QEFNIMEKNKGWALLGGKDG HLQGLFLLANALLERNQLLA QKVMYLLVPLLNRGNDKHKL TSAGSFVELLRSPVAKRLPS IYSVARFKDWLQDGNHLFRI LGLRGLYNLVGHQEMREDIK SLLPYIVDSLRETDEKIVLS AIQILLQLVRTMDFTTLAAM MRTLFSLFGDVRSDVHRFSV TLFGAAIKSVKNPDKKSIEN QVLDSLVPLLLYSQDENDAV AEESRQVLTICAQFLKWKLP QEVYSKDPWHIKPTEAGTIC RFFEKKCKGKINILEQTLMY SKNPKLPIRRSAVLFVGLLS KYMDHNELRRMGTDWIEDDL RDLLCDPEPSLCIIASQTLL LVQMARAEPKPKQRVNWLQK LMGRSSA in isoform 2. 1 Publication | 3 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK093432 mRNA Translation: BAC04162.1 Different initiation. AL031659 Genomic DNA No translation available. AL136172 Genomic DNA No translation available. AL833864 mRNA Translation: CAD38722.1 |
RefSeqi | NP_689716.4, NM_152503.5 NP_998796.1, NM_213631.2 NP_998797.2, NM_213632.2 |
Genome annotation databases
GeneIDi | 140699 |
KEGGi | hsa:140699 |
UCSCi | uc061wux.1, human [Q9H579-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK093432 mRNA Translation: BAC04162.1 Different initiation. AL031659 Genomic DNA No translation available. AL136172 Genomic DNA No translation available. AL833864 mRNA Translation: CAD38722.1 |
RefSeqi | NP_689716.4, NM_152503.5 NP_998796.1, NM_213631.2 NP_998797.2, NM_213632.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 126660, 4 interactors |
STRINGi | 9606.ENSP00000339971 |
PTM databases
iPTMneti | Q9H579 |
Genetic variation databases
BioMutai | MROH8 |
DMDMi | 28201794 |
Proteomic databases
MassIVEi | Q9H579 |
PeptideAtlasi | Q9H579 |
PRIDEi | Q9H579 |
ProteomicsDBi | 80895 [Q9H579-1] 80896 [Q9H579-2] |
Protocols and materials databases
Antibodypediai | 26648, 83 antibodies |
DNASUi | 140699 |
Genome annotation databases
GeneIDi | 140699 |
KEGGi | hsa:140699 |
UCSCi | uc061wux.1, human [Q9H579-1] |
Organism-specific databases
CTDi | 140699 |
DisGeNETi | 140699 |
GeneCardsi | MROH8 |
HGNCi | HGNC:16125, MROH8 |
HPAi | ENSG00000101353, Tissue enhanced (testis) |
neXtProti | NX_Q9H579 |
PharmGKBi | PA25674 |
VEuPathDBi | HostDB:ENSG00000101353.14 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG2032, Eukaryota |
InParanoidi | Q9H579 |
OMAi | RMKGTDW |
OrthoDBi | 31329at2759 |
PhylomeDBi | Q9H579 |
Enzyme and pathway databases
PathwayCommonsi | Q9H579 |
Miscellaneous databases
BioGRID-ORCSi | 140699, 6 hits in 188 CRISPR screens |
ChiTaRSi | MROH8, human |
GeneWikii | C20orf132 |
GenomeRNAii | 140699 |
Pharosi | Q9H579, Tdark |
PROi | PR:Q9H579 |
RNActi | Q9H579, protein |
Gene expression databases
Bgeei | ENSG00000101353, Expressed in testis and 149 other tissues |
ExpressionAtlasi | Q9H579, baseline and differential |
Genevisiblei | Q9H579, HS |
Family and domain databases
InterProi | View protein in InterPro IPR016024, ARM-type_fold |
SUPFAMi | SSF48371, SSF48371, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MROH8_HUMAN | |
Accessioni | Q9H579Primary (citable) accession number: Q9H579 Secondary accession number(s): Q5JYQ6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 2003 |
Last sequence update: | February 1, 2003 | |
Last modified: | April 7, 2021 | |
This is version 125 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 20
Human chromosome 20: entries, gene names and cross-references to MIM