UniProtKB - Q9H4L3 (Q9H4L3_HUMAN)
Protein
Submitted name:
Breast and ovarian cancer susceptibility protein 2
Gene
BRCA2
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
GO - Biological processi
- double-strand break repair via homologous recombination Source: InterPro
Keywordsi
Molecular function | DNA-bindingARBA annotation |
Biological process | DNA recombinationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Breast and ovarian cancer susceptibility protein 2ImportedSubmitted name: Breast cancer 2 tumor suppressorImported |
Gene namesi | Name:BRCA2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 56 | BRCA-2_helicalInterPro annotationAdd BLAST | 56 |
Family and domain databases
InterProi | View protein in InterPro IPR015525, BRCA2 IPR015252, BRCA2_hlx IPR036315, BRCA2_hlx_sf |
PANTHERi | PTHR11289, PTHR11289, 1 hit |
Pfami | View protein in Pfam PF09169, BRCA-2_helical, 1 hit |
SUPFAMi | SSF81872, SSF81872, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q9H4L3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
ALCDTPGVDP KLISRIWVYN HYRWIIWKLA AMECAFPKEF ANRCLSPERV
LLQLKY
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 56 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY008850 Genomic DNA Translation: AAG32681.1 DQ889340 Genomic DNA Translation: ABJ90481.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY008850 Genomic DNA Translation: AAG32681.1 DQ889340 Genomic DNA Translation: ABJ90481.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q9H4L3 |
Miscellaneous databases
ChiTaRSi | BRCA2, human |
Family and domain databases
InterProi | View protein in InterPro IPR015525, BRCA2 IPR015252, BRCA2_hlx IPR036315, BRCA2_hlx_sf |
PANTHERi | PTHR11289, PTHR11289, 1 hit |
Pfami | View protein in Pfam PF09169, BRCA-2_helical, 1 hit |
SUPFAMi | SSF81872, SSF81872, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9H4L3_HUMAN | |
Accessioni | Q9H4L3Primary (citable) accession number: Q9H4L3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2001 |
Last sequence update: | March 1, 2001 | |
Last modified: | October 7, 2020 | |
This is version 76 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |