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Entry version 165 (12 Aug 2020)
Sequence version 2 (11 Jul 2002)
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Protein

Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase

Gene

ST6GALNAC4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the biosynthesis of ganglioside GD1A from GM1B. Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc residue on NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc of glycoproteins and glycolipids. Prefers glycoproteins to glycolipids (By similarity).By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:HS06223-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.4.99.7, 2681

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9H4F1

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-4085001, Sialic acid metabolism
R-HSA-977068, Termination of O-glycan biosynthesis

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00378

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GT29, Glycosyltransferase Family 29

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase (EC:2.4.99.7)
Alternative name(s):
NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase
ST6GalNAc IV
Short name:
ST6GalNAcIV
Sialyltransferase 3C
Short name:
SIAT3-C
Sialyltransferase 7D
Short name:
SIAT7-D
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ST6GALNAC4
Synonyms:SIAT3C, SIAT7D
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000136840.18

Human Gene Nomenclature Database

More...
HGNCi
HGNC:17846, ST6GALNAC4

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606378, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H4F1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 6CytoplasmicSequence analysis6
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei7 – 27Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini28 – 302LumenalSequence analysisAdd BLAST275

Keywords - Cellular componenti

Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
27090

Open Targets

More...
OpenTargetsi
ENSG00000136840

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA38250

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9H4F1, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ST6GALNAC4

Domain mapping of disease mutations (DMDM)

More...
DMDMi
21759443

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001492781 – 302Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferaseAdd BLAST302

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi76 ↔ 225By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi135N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H4F1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H4F1

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9H4F1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H4F1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H4F1

PeptideAtlas

More...
PeptideAtlasi
Q9H4F1

PRoteomics IDEntifications database

More...
PRIDEi
Q9H4F1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
80828

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q9H4F1, 1 site

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H4F1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H4F1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000136840, Expressed in body of pancreas and 198 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9H4F1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H4F1, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000136840, Tissue enhanced (blood, pancreas)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
117992, 12 interactors

Protein interaction database and analysis system

More...
IntActi
Q9H4F1, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000336733

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9H4F1, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyltransferase 29 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2692, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157958

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_061099_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H4F1

KEGG Orthology (KO)

More...
KOi
K03374

Identification of Orthologs from Complete Genome Data

More...
OMAi
SYCREES

Database of Orthologous Groups

More...
OrthoDBi
817470at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H4F1

TreeFam database of animal gene trees

More...
TreeFami
TF352818

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.90.1480.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001675, Glyco_trans_29
IPR038578, GT29-like_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00777, Glyco_transf_29, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9H4F1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKAPGRLVLI ILCSVVFSAV YILLCCWAGL PLCLATCLDH HFPTGSRPTV
60 70 80 90 100
PGPLHFSGYS SVPDGKPLVR EPCRSCAVVS SSGQMLGSGL GAEIDSAECV
110 120 130 140 150
FRMNQAPTVG FEADVGQRST LRVVSHTSVP LLLRNYSHYF QKARDTLYMV
160 170 180 190 200
WGQGRHMDRV LGGRTYRTLL QLTRMYPGLQ VYTFTERMMA YCDQIFQDET
210 220 230 240 250
GKNRRQSGSF LSTGWFTMIL ALELCEEIVV YGMVSDSYCR EKSHPSVPYH
260 270 280 290 300
YFEKGRLDEC QMYLAHEQAP RSAHRFITEK AVFSRWAKKR PIVFAHPSWR

TE
Length:302
Mass (Da):34,201
Last modified:July 11, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i08A4CDC749A6D783
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A6NJX0A6NJX0_HUMAN
Alpha-N-acetyl-neuraminyl-2,3-beta-...
ST6GALNAC4
200Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti119 – 120ST → QA in AAF00102 (Ref. 2) Curated2
Sequence conflicti119S → T in CAC07404 (PubMed:11062056).Curated1
Sequence conflicti140F → L in BAA91281 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ271734 mRNA Translation: CAC07404.1
AF127142 mRNA Translation: AAF00102.1
AB035172 mRNA Translation: BAA87034.1
AK000600 mRNA Translation: BAA91281.1
AL157935 Genomic DNA No translation available.
CH471090 Genomic DNA Translation: EAW87717.1
BC036705 mRNA Translation: AAH36705.1
Y17460 Genomic DNA Translation: CAB44353.1
Y17461 Genomic DNA Translation: CAB44354.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS6883.1

NCBI Reference Sequences

More...
RefSeqi
NP_778204.1, NM_175039.3
NP_778205.1, NM_175040.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000335791; ENSP00000336733; ENSG00000136840

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
27090

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:27090

UCSC genome browser

More...
UCSCi
uc004bss.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Functional Glycomics Gateway - GTase

ST6GalNAc IV

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ271734 mRNA Translation: CAC07404.1
AF127142 mRNA Translation: AAF00102.1
AB035172 mRNA Translation: BAA87034.1
AK000600 mRNA Translation: BAA91281.1
AL157935 Genomic DNA No translation available.
CH471090 Genomic DNA Translation: EAW87717.1
BC036705 mRNA Translation: AAH36705.1
Y17460 Genomic DNA Translation: CAB44353.1
Y17461 Genomic DNA Translation: CAB44354.1
CCDSiCCDS6883.1
RefSeqiNP_778204.1, NM_175039.3
NP_778205.1, NM_175040.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi117992, 12 interactors
IntActiQ9H4F1, 3 interactors
STRINGi9606.ENSP00000336733

Protein family/group databases

CAZyiGT29, Glycosyltransferase Family 29

PTM databases

GlyGeniQ9H4F1, 1 site
iPTMnetiQ9H4F1
PhosphoSitePlusiQ9H4F1

Polymorphism and mutation databases

BioMutaiST6GALNAC4
DMDMi21759443

Proteomic databases

EPDiQ9H4F1
jPOSTiQ9H4F1
MassIVEiQ9H4F1
MaxQBiQ9H4F1
PaxDbiQ9H4F1
PeptideAtlasiQ9H4F1
PRIDEiQ9H4F1
ProteomicsDBi80828

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2464, 89 antibodies

The DNASU plasmid repository

More...
DNASUi
27090

Genome annotation databases

EnsembliENST00000335791; ENSP00000336733; ENSG00000136840
GeneIDi27090
KEGGihsa:27090
UCSCiuc004bss.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
27090
DisGeNETi27090
EuPathDBiHostDB:ENSG00000136840.18

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ST6GALNAC4
HGNCiHGNC:17846, ST6GALNAC4
HPAiENSG00000136840, Tissue enhanced (blood, pancreas)
MIMi606378, gene
neXtProtiNX_Q9H4F1
OpenTargetsiENSG00000136840
PharmGKBiPA38250

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2692, Eukaryota
GeneTreeiENSGT00940000157958
HOGENOMiCLU_061099_1_0_1
InParanoidiQ9H4F1
KOiK03374
OMAiSYCREES
OrthoDBi817470at2759
PhylomeDBiQ9H4F1
TreeFamiTF352818

Enzyme and pathway databases

UniPathwayiUPA00378
BioCyciMetaCyc:HS06223-MONOMER
BRENDAi2.4.99.7, 2681
PathwayCommonsiQ9H4F1
ReactomeiR-HSA-4085001, Sialic acid metabolism
R-HSA-977068, Termination of O-glycan biosynthesis

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
27090, 9 hits in 874 CRISPR screens

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
ST6GALNAC4

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
27090
PharosiQ9H4F1, Tbio

Protein Ontology

More...
PROi
PR:Q9H4F1
RNActiQ9H4F1, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000136840, Expressed in body of pancreas and 198 other tissues
ExpressionAtlasiQ9H4F1, baseline and differential
GenevisibleiQ9H4F1, HS

Family and domain databases

Gene3Di3.90.1480.20, 1 hit
InterProiView protein in InterPro
IPR001675, Glyco_trans_29
IPR038578, GT29-like_sf
PfamiView protein in Pfam
PF00777, Glyco_transf_29, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSIA7D_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H4F1
Secondary accession number(s): Q5T9D0
, Q9NWU6, Q9UKU1, Q9ULB9, Q9Y3G3, Q9Y3G4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: July 11, 2002
Last modified: August 12, 2020
This is version 165 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
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