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Entry version 142 (17 Jun 2020)
Sequence version 1 (01 Mar 2001)
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Protein

GPI mannosyltransferase 1

Gene

PIGM

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: glycosylphosphatidylinositol-anchor biosynthesis

This protein is involved in the pathway glycosylphosphatidylinositol-anchor biosynthesis, which is part of Glycolipid biosynthesis.
View all proteins of this organism that are known to be involved in the pathway glycosylphosphatidylinositol-anchor biosynthesis and in Glycolipid biosynthesis.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processGPI-anchor biosynthesis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-162710 Synthesis of glycosylphosphatidylinositol (GPI)

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00196

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GT50 Glycosyltransferase Family 50

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
GPI mannosyltransferase 1 (EC:2.4.1.-)
Alternative name(s):
GPI mannosyltransferase I
Short name:
GPI-MT-I
Phosphatidylinositol-glycan biosynthesis class M protein
Short name:
PIG-M
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PIGM
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000143315.6

Human Gene Nomenclature Database

More...
HGNCi
HGNC:18858 PIGM

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610273 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H3S5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 17CytoplasmicSequence analysisAdd BLAST17
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei18 – 38HelicalSequence analysisAdd BLAST21
Topological domaini39 – 79LumenalSequence analysisAdd BLAST41
Transmembranei80 – 100HelicalSequence analysisAdd BLAST21
Topological domaini101 – 138CytoplasmicSequence analysisAdd BLAST38
Transmembranei139 – 161HelicalSequence analysisAdd BLAST23
Topological domaini162 – 169LumenalSequence analysis8
Transmembranei170 – 190HelicalSequence analysisAdd BLAST21
Topological domaini191 – 225CytoplasmicSequence analysisAdd BLAST35
Transmembranei226 – 246HelicalSequence analysisAdd BLAST21
Topological domaini247 – 287LumenalSequence analysisAdd BLAST41
Transmembranei288 – 308HelicalSequence analysisAdd BLAST21
Topological domaini309 – 314CytoplasmicSequence analysis6
Transmembranei315 – 337HelicalSequence analysisAdd BLAST23
Topological domaini338LumenalSequence analysis1
Transmembranei339 – 350HelicalSequence analysisAdd BLAST12
Topological domaini351 – 357CytoplasmicSequence analysis7
Transmembranei358 – 378HelicalSequence analysisAdd BLAST21
Topological domaini379 – 384LumenalSequence analysis6
Transmembranei385 – 405HelicalSequence analysisAdd BLAST21
Topological domaini406 – 423CytoplasmicSequence analysisAdd BLAST18

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Glycosylphosphatidylinositol deficiency (GPID)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionAutosomal recessive trait that results in a propensity to venous thrombosis and seizures. Deficiency is due to a point mutation in the regulatory sequences of PIGM that disrupts binding of the transcription factor SP1 to its cognate promoter motif, leading to a strong reduction of expression.
Related information in OMIM

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi49D → A: Almost abolishes enzyme activity. 1 Publication1
Mutagenesisi51D → A: Abolishes enzyme activity. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
93183

MalaCards human disease database

More...
MalaCardsi
PIGM
MIMi610293 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000143315

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
83639 Hypercoagulability syndrome due to glycosylphosphatidylinositol deficiency

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA38718

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9H3S5 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PIGM

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74752622

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002462131 – 423GPI mannosyltransferase 1Add BLAST423

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H3S5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H3S5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9H3S5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H3S5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H3S5

PeptideAtlas

More...
PeptideAtlasi
Q9H3S5

PRoteomics IDEntifications database

More...
PRIDEi
Q9H3S5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
80749

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H3S5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H3S5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000143315 Expressed in nasal cavity epithelium and 201 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H3S5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000143315 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
125010, 18 interactors

Protein interaction database and analysis system

More...
IntActi
Q9H3S5, 11 interactors

Molecular INTeraction database

More...
MINTi
Q9H3S5

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000357069

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9H3S5 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PIGM family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3893 Eukaryota
ENOG410XRDY LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000017728

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_024220_3_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H3S5

KEGG Orthology (KO)

More...
KOi
K05284

Identification of Orthologs from Complete Genome Data

More...
OMAi
IQIISHY

Database of Orthologous Groups

More...
OrthoDBi
1003258at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H3S5

TreeFam database of animal gene trees

More...
TreeFami
TF314752

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007704 PIG-M

The PANTHER Classification System

More...
PANTHERi
PTHR12886 PTHR12886, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05007 Mannosyl_trans, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9H3S5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSTKHWGEW LLNLKVAPAG VFGVAFLARV ALVFYGVFQD RTLHVRYTDI
60 70 80 90 100
DYQVFTDAAR FVTEGRSPYL RATYRYTPLL GWLLTPNIYL SELFGKFLFI
110 120 130 140 150
SCDLLTAFLL YRLLLLKGLG RRQACGYCVF WLLNPLPMAV SSRGNADSIV
160 170 180 190 200
ASLVLMVLYL IKKRLVACAA VFYGFAVHMK IYPVTYILPI TLHLLPDRDN
210 220 230 240 250
DKSLRQFRYT FQACLYELLK RLCNRAVLLF VAVAGLTFFA LSFGFYYEYG
260 270 280 290 300
WEFLEHTYFY HLTRRDIRHN FSPYFYMLYL TAESKWSFSL GIAAFLPQLI
310 320 330 340 350
LLSAVSFAYY RDLVFCCFLH TSIFVTFNKV CTSQYFLWYL CLLPLVMPLV
360 370 380 390 400
RMPWKRAVVL LMLWFIGQAM WLAPAYVLEF QGKNTFLFIW LAGLFFLLIN
410 420
CSILIQIISH YKEEPLTERI KYD
Length:423
Mass (Da):49,460
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE17DCD8252E28EF0
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_027026365F → L. Corresponds to variant dbSNP:rs12409352Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB028127 mRNA Translation: BAB18567.1
AK074655 mRNA Translation: BAC11116.1
AL513302 Genomic DNA No translation available.
BC001803 mRNA Translation: AAH01803.1
BC019865 mRNA Translation: AAH19865.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1192.1

NCBI Reference Sequences

More...
RefSeqi
NP_660150.1, NM_145167.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000368090; ENSP00000357069; ENSG00000143315

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
93183

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:93183

UCSC genome browser

More...
UCSCi
uc001fuv.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB028127 mRNA Translation: BAB18567.1
AK074655 mRNA Translation: BAC11116.1
AL513302 Genomic DNA No translation available.
BC001803 mRNA Translation: AAH01803.1
BC019865 mRNA Translation: AAH19865.1
CCDSiCCDS1192.1
RefSeqiNP_660150.1, NM_145167.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi125010, 18 interactors
IntActiQ9H3S5, 11 interactors
MINTiQ9H3S5
STRINGi9606.ENSP00000357069

Protein family/group databases

CAZyiGT50 Glycosyltransferase Family 50

PTM databases

iPTMnetiQ9H3S5
PhosphoSitePlusiQ9H3S5

Polymorphism and mutation databases

BioMutaiPIGM
DMDMi74752622

Proteomic databases

EPDiQ9H3S5
jPOSTiQ9H3S5
MassIVEiQ9H3S5
MaxQBiQ9H3S5
PaxDbiQ9H3S5
PeptideAtlasiQ9H3S5
PRIDEiQ9H3S5
ProteomicsDBi80749

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
34265 71 antibodies

The DNASU plasmid repository

More...
DNASUi
93183

Genome annotation databases

EnsembliENST00000368090; ENSP00000357069; ENSG00000143315
GeneIDi93183
KEGGihsa:93183
UCSCiuc001fuv.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
93183
DisGeNETi93183
EuPathDBiHostDB:ENSG00000143315.6

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PIGM
HGNCiHGNC:18858 PIGM
HPAiENSG00000143315 Low tissue specificity
MalaCardsiPIGM
MIMi610273 gene
610293 phenotype
neXtProtiNX_Q9H3S5
OpenTargetsiENSG00000143315
Orphaneti83639 Hypercoagulability syndrome due to glycosylphosphatidylinositol deficiency
PharmGKBiPA38718

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3893 Eukaryota
ENOG410XRDY LUCA
GeneTreeiENSGT00390000017728
HOGENOMiCLU_024220_3_1_1
InParanoidiQ9H3S5
KOiK05284
OMAiIQIISHY
OrthoDBi1003258at2759
PhylomeDBiQ9H3S5
TreeFamiTF314752

Enzyme and pathway databases

UniPathwayiUPA00196
ReactomeiR-HSA-162710 Synthesis of glycosylphosphatidylinositol (GPI)

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
93183 18 hits in 787 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PIGM human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
93183
PharosiQ9H3S5 Tbio

Protein Ontology

More...
PROi
PR:Q9H3S5
RNActiQ9H3S5 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000143315 Expressed in nasal cavity epithelium and 201 other tissues
GenevisibleiQ9H3S5 HS

Family and domain databases

InterProiView protein in InterPro
IPR007704 PIG-M
PANTHERiPTHR12886 PTHR12886, 1 hit
PfamiView protein in Pfam
PF05007 Mannosyl_trans, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPIGM_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H3S5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: March 1, 2001
Last modified: June 17, 2020
This is version 142 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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