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Entry version 114 (12 Aug 2020)
Sequence version 1 (01 Mar 2001)
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Protein

Transmembrane protein 60

Gene

TMEM60

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9H2L4

Protein family/group databases

Transport Classification Database

More...
TCDBi
8.A.76.1.2, the tmem203 or pf14967 (tmem203) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 60
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMEM60
Synonyms:C7orf35
ORF Names:DC32
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000135211.5

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21754, TMEM60

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H2L4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei5 – 25HelicalSequence analysisAdd BLAST21
Transmembranei35 – 55HelicalSequence analysisAdd BLAST21
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Transmembranei110 – 130HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
85025

Open Targets

More...
OpenTargetsi
ENSG00000135211

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134910139

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9H2L4, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TMEM60

Domain mapping of disease mutations (DMDM)

More...
DMDMi
47605551

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000725811 – 133Transmembrane protein 60Add BLAST133

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H2L4

PeptideAtlas

More...
PeptideAtlasi
Q9H2L4

PRoteomics IDEntifications database

More...
PRIDEi
Q9H2L4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
80561

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000135211, Expressed in secondary oocyte and 213 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H2L4, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000135211, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q9H2L4
With#Exp.IntAct
AMIGO1 [Q86WK6]3EBI-2852148,EBI-19125216
ANKS6 [Q68DC2]3EBI-2852148,EBI-7054139
APOL2 [Q9BQE5]3EBI-2852148,EBI-4290634
AQP2 [P41181]3EBI-2852148,EBI-12701138
AQP6 [Q13520]3EBI-2852148,EBI-13059134
ASGR2 - isoform 3 [P07307-3]3EBI-2852148,EBI-12808270
BEST2 [Q8NFU1]3EBI-2852148,EBI-19947314
BIK [Q13323]3EBI-2852148,EBI-700794
BSND [Q8WZ55]3EBI-2852148,EBI-7996695
CD300A [Q9UGN4]3EBI-2852148,EBI-10320732
CD53 [P19397]3EBI-2852148,EBI-6657396
CD74 - isoform 2 [P04233-2]3EBI-2852148,EBI-12222807
CLDN7 [O95471]3EBI-2852148,EBI-740744
CNR2 [P34972]3EBI-2852148,EBI-2835940
CPLX4 [Q7Z7G2]3EBI-2852148,EBI-18013275
CYB5R3 [P00387]3EBI-2852148,EBI-1046040
EBP [Q15125]3EBI-2852148,EBI-3915253
EDA [Q92838]3EBI-2852148,EBI-529425
ERGIC3 [Q9Y282]3EBI-2852148,EBI-781551
ERVFRD-1 [P60508]3EBI-2852148,EBI-17973325
EVI2B - isoform 2 [P34910-2]3EBI-2852148,EBI-17640610
FAM209A [Q5JX71]3EBI-2852148,EBI-18304435
FFAR2 [O15552]3EBI-2852148,EBI-2833872
FNDC9 [Q8TBE3]3EBI-2852148,EBI-12142257
GJA8 [P48165]3EBI-2852148,EBI-17458373
GJB5 [O95377]3EBI-2852148,EBI-3909454
GJB6 [O95452]3EBI-2852148,EBI-13345609
GORAB [Q5T7V8]3EBI-2852148,EBI-3917143
GPR152 [Q8TDT2]3EBI-2852148,EBI-13345167
GPR42 [O15529]3EBI-2852148,EBI-18076404
GPR61 [Q9BZJ8]3EBI-2852148,EBI-12808020
GPX8 [Q8TED1]3EBI-2852148,EBI-11721746
HERPUD2 [Q9BSE4]3EBI-2852148,EBI-2868124
HIBADH [P31937]3EBI-2852148,EBI-11427100
HSD17B11 [Q8NBQ5]3EBI-2852148,EBI-1052304
HSD17B13 [Q7Z5P4]3EBI-2852148,EBI-18053395
IFNGR2 [P38484]3EBI-2852148,EBI-3905457
IL10RA [Q13651]3EBI-2852148,EBI-1031656
IL7R [P16871]3EBI-2852148,EBI-80490
KCNK5 [O95279]3EBI-2852148,EBI-3934936
KIAA2013 [Q8IYS2]3EBI-2852148,EBI-2866116
LEPROTL1 [O95214]3EBI-2852148,EBI-750776
LEUTX [A8MZ59]3EBI-2852148,EBI-17490413
LHFPL5 [Q8TAF8]3EBI-2852148,EBI-2820517
LRRC3B [Q96PB8]3EBI-2852148,EBI-17775622
LRRC59 [Q96AG4]3EBI-2852148,EBI-358888
MFF - isoform 5 [Q9GZY8-5]3EBI-2852148,EBI-11956541
MGST3 [O14880]3EBI-2852148,EBI-724754
MMD [Q15546]3EBI-2852148,EBI-17873222
MMGT1 [Q8N4V1]3EBI-2852148,EBI-6163737
PAGE1 [O75459]3EBI-2852148,EBI-2559100
PGRMC2 [O15173]3EBI-2852148,EBI-1050125
PI16 [Q6UXB8]3EBI-2852148,EBI-12810028
REEP2 [Q9BRK0]3EBI-2852148,EBI-11337973
REEP4 [Q9H6H4]3EBI-2852148,EBI-7545592
RETREG3 [Q86VR2]3EBI-2852148,EBI-10192441
RHCG [Q9UBD6]3EBI-2852148,EBI-15853497
RNASEK [Q6P5S7]3EBI-2852148,EBI-18397230
SAR1A [Q9NR31]3EBI-2852148,EBI-3920694
SCN3B [Q9NY72]3EBI-2852148,EBI-17247926
SLC10A1 [Q14973]3EBI-2852148,EBI-3923031
SLC10A6 [Q3KNW5]3EBI-2852148,EBI-18159983
SLC13A4 [Q9UKG4]3EBI-2852148,EBI-12808018
SLC18A1 - isoform 3 [P54219-3]3EBI-2852148,EBI-17595455
SLC30A2 [Q9BRI3]5EBI-2852148,EBI-8644112
SLC30A4 [O14863]3EBI-2852148,EBI-13918058
SLC35E3 [Q7Z769]3EBI-2852148,EBI-13389236
SLC38A1 [Q9H2H9]3EBI-2852148,EBI-9978441
SLC39A1 [Q9NY26]3EBI-2852148,EBI-726491
SLC39A2 [Q9NP94]3EBI-2852148,EBI-12898013
SLC4A1 [P02730]3EBI-2852148,EBI-7576138
SLC6A15 [Q9H2J7]3EBI-2852148,EBI-11343466
SLC7A8 [Q9UHI5]3EBI-2852148,EBI-13292283
SPAG4 [Q9NPE6]3EBI-2852148,EBI-10819434
SPNS3 - isoform 2 [Q6ZMD2-2]3EBI-2852148,EBI-17848320
SSMEM1 [Q8WWF3]3EBI-2852148,EBI-17280858
STOM [P27105]3EBI-2852148,EBI-1211440
STX1A [Q16623]3EBI-2852148,EBI-712466
SYT1 [P21579]3EBI-2852148,EBI-524909
THAP4 [Q8WY91]3EBI-2852148,EBI-726691
TLCD4 [Q96MV1]3EBI-2852148,EBI-12947623
TMCO5A [Q8N6Q1]3EBI-2852148,EBI-12821895
TMED9 [Q9BVK6]3EBI-2852148,EBI-1056827
TMEM139 [Q8IV31]3EBI-2852148,EBI-7238458
TMEM14B [Q9NUH8]3EBI-2852148,EBI-8638294
TMEM203 [Q969S6]3EBI-2852148,EBI-12274070
TMEM237 - isoform 2 [Q96Q45-2]3EBI-2852148,EBI-10982110
TMEM45B [Q96B21]3EBI-2852148,EBI-3923061
TMEM52B [Q4KMG9]3EBI-2852148,EBI-18178701
TMEM86B [Q8N661]3EBI-2852148,EBI-2548832
TMEM9 [Q9P0T7]3EBI-2852148,EBI-723976
TMPPE [Q6ZT21]3EBI-2852148,EBI-11724433
TMPRSS2 - isoform 2 [O15393-2]3EBI-2852148,EBI-12345267
TTYH1 - isoform 4 [Q9H313-4]3EBI-2852148,EBI-17671298
VMA21 [Q3ZAQ7]3EBI-2852148,EBI-1055364

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
124434, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q9H2L4, 96 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000257663

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9H2L4, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3879, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000007283

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_152149_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H2L4

Identification of Orthologs from Complete Genome Data

More...
OMAi
WYLVAML

Database of Orthologous Groups

More...
OrthoDBi
1512798at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H2L4

TreeFam database of animal gene trees

More...
TreeFami
TF325897

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019396, TM_Fragile-X-F-assoc

The PANTHER Classification System

More...
PANTHERi
PTHR13568, PTHR13568, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10269, Tmemb_185A, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9H2L4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRMSLAQRVL LTWLFTLLFL IMLVLKLDEK APWNWFLIFI PVWIFDTILL
60 70 80 90 100
VLLIVKMAGR CKSGFDPRHG SHNIKKKAWY LIAMLLKLAF CLALCAKLEQ
110 120 130
FTTMNLSYVF IPLWALLAGA LTELGYNVFF VRD
Length:133
Mass (Da):15,500
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9E4064FF94F70A7D
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH65930 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05144942V → G. Corresponds to variant dbSNP:rs34580932Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF260336 mRNA Translation: AAG44667.1
AC004955 Genomic DNA Translation: AAP21882.1
AC004955 Genomic DNA Translation: AAP21883.1
CH236949 Genomic DNA Translation: EAL24196.1
CH471091 Genomic DNA Translation: EAW77032.1
BC065930 mRNA Translation: AAH65930.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5593.1

NCBI Reference Sequences

More...
RefSeqi
NP_116325.1, NM_032936.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000257663; ENSP00000257663; ENSG00000135211

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
85025

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:85025

UCSC genome browser

More...
UCSCi
uc003ugn.4, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF260336 mRNA Translation: AAG44667.1
AC004955 Genomic DNA Translation: AAP21882.1
AC004955 Genomic DNA Translation: AAP21883.1
CH236949 Genomic DNA Translation: EAL24196.1
CH471091 Genomic DNA Translation: EAW77032.1
BC065930 mRNA Translation: AAH65930.1 Different initiation.
CCDSiCCDS5593.1
RefSeqiNP_116325.1, NM_032936.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi124434, 1 interactor
IntActiQ9H2L4, 96 interactors
STRINGi9606.ENSP00000257663

Protein family/group databases

TCDBi8.A.76.1.2, the tmem203 or pf14967 (tmem203) family

Polymorphism and mutation databases

BioMutaiTMEM60
DMDMi47605551

Proteomic databases

PaxDbiQ9H2L4
PeptideAtlasiQ9H2L4
PRIDEiQ9H2L4
ProteomicsDBi80561

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
71000, 4 antibodies

Genome annotation databases

EnsembliENST00000257663; ENSP00000257663; ENSG00000135211
GeneIDi85025
KEGGihsa:85025
UCSCiuc003ugn.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
85025
DisGeNETi85025
EuPathDBiHostDB:ENSG00000135211.5

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TMEM60
HGNCiHGNC:21754, TMEM60
HPAiENSG00000135211, Low tissue specificity
neXtProtiNX_Q9H2L4
OpenTargetsiENSG00000135211
PharmGKBiPA134910139

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3879, Eukaryota
GeneTreeiENSGT00390000007283
HOGENOMiCLU_152149_0_0_1
InParanoidiQ9H2L4
OMAiWYLVAML
OrthoDBi1512798at2759
PhylomeDBiQ9H2L4
TreeFamiTF325897

Enzyme and pathway databases

PathwayCommonsiQ9H2L4

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
85025, 7 hits in 875 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TMEM60, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
85025
PharosiQ9H2L4, Tdark

Protein Ontology

More...
PROi
PR:Q9H2L4
RNActiQ9H2L4, protein

Gene expression databases

BgeeiENSG00000135211, Expressed in secondary oocyte and 213 other tissues
GenevisibleiQ9H2L4, HS

Family and domain databases

InterProiView protein in InterPro
IPR019396, TM_Fragile-X-F-assoc
PANTHERiPTHR13568, PTHR13568, 1 hit
PfamiView protein in Pfam
PF10269, Tmemb_185A, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTMM60_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H2L4
Secondary accession number(s): A4D1C3, Q86UM0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2001
Last modified: August 12, 2020
This is version 114 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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