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UniProtKB - Q9H2L4 (TMM60_HUMAN)

Entry version 122 (25 May 2022)
Sequence version 1 (01 Mar 2001)
Previous versions | rss
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Protein

Transmembrane protein 60

Gene

TMEM60

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9H2L4

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9H2L4

Protein family/group databases

Transport Classification Database

More...TCDBi		8.A.76.1.2, the tmem203 or pf14967 (tmem203) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 60
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMEM60
Synonyms:C7orf35
ORF Names:DC32
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:21754, TMEM60

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9H2L4

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000135211

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei5 – 25HelicalSequence analysisAdd BLAST21
Transmembranei35 – 55HelicalSequence analysisAdd BLAST21
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Transmembranei110 – 130HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		85025

Open Targets

More...OpenTargetsi		ENSG00000135211

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134910139

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9H2L4, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TMEM60

Domain mapping of disease mutations (DMDM)

More...DMDMi		47605551

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000725811 – 133Transmembrane protein 60Add BLAST133

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9H2L4

PRoteomics IDEntifications database

More...PRIDEi		Q9H2L4

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		80561

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000135211, Expressed in secondary oocyte and 213 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9H2L4, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000135211, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q9H2L4
With#Exp.IntAct
AMIGO1 [Q86WK6]3EBI-2852148,EBI-19125216
ANKS6 [Q68DC2]3EBI-2852148,EBI-7054139
APOL2 [Q9BQE5]3EBI-2852148,EBI-4290634
AQP2 [P41181]3EBI-2852148,EBI-12701138
AQP6 [Q13520]3EBI-2852148,EBI-13059134
ASGR2 - isoform 3 [P07307-3]3EBI-2852148,EBI-12808270
BEST2 [Q8NFU1]3EBI-2852148,EBI-19947314
BIK [Q13323]3EBI-2852148,EBI-700794
BSND [Q8WZ55]3EBI-2852148,EBI-7996695
CD300A [Q9UGN4]3EBI-2852148,EBI-10320732
CD53 [P19397]3EBI-2852148,EBI-6657396
CD74 - isoform p35 [P04233-2]3EBI-2852148,EBI-12222807
CLDN7 [O95471]3EBI-2852148,EBI-740744
CNR2 [P34972]3EBI-2852148,EBI-2835940
CPLX4 [Q7Z7G2]3EBI-2852148,EBI-18013275
CYB5R3 [P00387]3EBI-2852148,EBI-1046040
EBP [Q15125]3EBI-2852148,EBI-3915253
EDA [Q92838]3EBI-2852148,EBI-529425
ERGIC3 [Q9Y282]3EBI-2852148,EBI-781551
ERVFRD-1 [P60508]3EBI-2852148,EBI-17973325
EVI2B - isoform 2 [P34910-2]3EBI-2852148,EBI-17640610
FAM209A [Q5JX71]3EBI-2852148,EBI-18304435
FFAR2 [O15552]3EBI-2852148,EBI-2833872
FNDC9 [Q8TBE3]3EBI-2852148,EBI-12142257
GJA8 [P48165]3EBI-2852148,EBI-17458373
GJB5 [O95377]3EBI-2852148,EBI-3909454
GJB6 [O95452]3EBI-2852148,EBI-13345609
GORAB [Q5T7V8]3EBI-2852148,EBI-3917143
GPR152 [Q8TDT2]3EBI-2852148,EBI-13345167
GPR42 [O15529]3EBI-2852148,EBI-18076404
GPR61 [Q9BZJ8]3EBI-2852148,EBI-12808020
GPX8 [Q8TED1]3EBI-2852148,EBI-11721746
HERPUD2 [Q9BSE4]3EBI-2852148,EBI-2868124
HIBADH [P31937]3EBI-2852148,EBI-11427100
HSD17B11 [Q8NBQ5]3EBI-2852148,EBI-1052304
HSD17B13 [Q7Z5P4]3EBI-2852148,EBI-18053395
IFNGR2 [P38484]3EBI-2852148,EBI-3905457
IL10RA [Q13651]3EBI-2852148,EBI-1031656
IL7R [P16871]3EBI-2852148,EBI-80490
KCNK5 [O95279]3EBI-2852148,EBI-3934936
KIAA2013 [Q8IYS2]3EBI-2852148,EBI-2866116
LEPROTL1 [O95214]3EBI-2852148,EBI-750776
LEUTX [A8MZ59]3EBI-2852148,EBI-17490413
LHFPL5 [Q8TAF8]3EBI-2852148,EBI-2820517
LRRC3B [Q96PB8]3EBI-2852148,EBI-17775622
LRRC59 [Q96AG4]3EBI-2852148,EBI-358888
MFF - isoform 5 [Q9GZY8-5]3EBI-2852148,EBI-11956541
MGST3 [O14880]3EBI-2852148,EBI-724754
MMD [Q15546]3EBI-2852148,EBI-17873222
MMGT1 [Q8N4V1]3EBI-2852148,EBI-6163737
PAGE1 [O75459]3EBI-2852148,EBI-2559100
PGRMC2 [O15173]3EBI-2852148,EBI-1050125
PI16 [Q6UXB8]3EBI-2852148,EBI-12810028
REEP2 [Q9BRK0]3EBI-2852148,EBI-11337973
REEP4 [Q9H6H4]3EBI-2852148,EBI-7545592
RETREG3 [Q86VR2]3EBI-2852148,EBI-10192441
RHCG [Q9UBD6]3EBI-2852148,EBI-15853497
RNASEK [Q6P5S7]3EBI-2852148,EBI-18397230
SAR1A [Q9NR31]3EBI-2852148,EBI-3920694
SCN3B [Q9NY72]3EBI-2852148,EBI-17247926
SLC10A1 [Q14973]3EBI-2852148,EBI-3923031
SLC10A6 [Q3KNW5]3EBI-2852148,EBI-18159983
SLC13A4 [Q9UKG4]3EBI-2852148,EBI-12808018
SLC18A1 - isoform 3 [P54219-3]3EBI-2852148,EBI-17595455
SLC30A2 [Q9BRI3]5EBI-2852148,EBI-8644112
SLC30A4 [O14863]3EBI-2852148,EBI-13918058
SLC35E3 [Q7Z769]3EBI-2852148,EBI-13389236
SLC38A1 [Q9H2H9]3EBI-2852148,EBI-9978441
SLC39A1 [Q9NY26]3EBI-2852148,EBI-726491
SLC39A2 [Q9NP94]3EBI-2852148,EBI-12898013
SLC4A1 [P02730]3EBI-2852148,EBI-7576138
SLC6A15 [Q9H2J7]3EBI-2852148,EBI-11343466
SLC7A8 [Q9UHI5]3EBI-2852148,EBI-13292283
SPAG4 [Q9NPE6]3EBI-2852148,EBI-10819434
SPNS3 - isoform 2 [Q6ZMD2-2]3EBI-2852148,EBI-17848320
SSMEM1 [Q8WWF3]3EBI-2852148,EBI-17280858
STOM [P27105]3EBI-2852148,EBI-1211440
STX1A [Q16623]3EBI-2852148,EBI-712466
SYT1 [P21579]3EBI-2852148,EBI-524909
THAP4 [Q8WY91]3EBI-2852148,EBI-726691
TLCD4 [Q96MV1]3EBI-2852148,EBI-12947623
TMCO5A [Q8N6Q1]3EBI-2852148,EBI-12821895
TMED9 [Q9BVK6]3EBI-2852148,EBI-1056827
TMEM139 [Q8IV31]3EBI-2852148,EBI-7238458
TMEM14B [Q9NUH8]3EBI-2852148,EBI-8638294
TMEM203 [Q969S6]3EBI-2852148,EBI-12274070
TMEM237 - isoform 2 [Q96Q45-2]3EBI-2852148,EBI-10982110
TMEM45B [Q96B21]3EBI-2852148,EBI-3923061
TMEM52B [Q4KMG9]3EBI-2852148,EBI-18178701
TMEM86B [Q8N661]3EBI-2852148,EBI-2548832
TMEM9 [Q9P0T7]3EBI-2852148,EBI-723976
TMPPE [Q6ZT21]3EBI-2852148,EBI-11724433
TMPRSS2 - isoform 2 [O15393-2]3EBI-2852148,EBI-12345267
TTYH1 - isoform 4 [Q9H313-4]3EBI-2852148,EBI-17671298
VMA21 [Q3ZAQ7]3EBI-2852148,EBI-1055364

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		124434, 89 interactors

Protein interaction database and analysis system

More...IntActi		Q9H2L4, 96 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000257663

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9H2L4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q9H2L4

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3879, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000007283

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_152149_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9H2L4

Identification of Orthologs from Complete Genome Data

More...OMAi		FIPLWLY

Database of Orthologous Groups

More...OrthoDBi		1512798at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9H2L4

TreeFam database of animal gene trees

More...TreeFami		TF325897

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR019396, TM_Fragile-X-F-assoc

The PANTHER Classification System

More...PANTHERi		PTHR13568, PTHR13568, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF10269, Tmemb_185A, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9H2L4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRMSLAQRVL LTWLFTLLFL IMLVLKLDEK APWNWFLIFI PVWIFDTILL 
        60         70         80         90        100
VLLIVKMAGR CKSGFDPRHG SHNIKKKAWY LIAMLLKLAF CLALCAKLEQ 
       110        120        130 
FTTMNLSYVF IPLWALLAGA LTELGYNVFF VRD
Length:133
Mass (Da):15,500
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9E4064FF94F70A7D
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH65930 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05144942V → G. Corresponds to variant dbSNP:rs34580932Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF260336 mRNA Translation: AAG44667.1
AC004955 Genomic DNA Translation: AAP21882.1
AC004955 Genomic DNA Translation: AAP21883.1
CH236949 Genomic DNA Translation: EAL24196.1
CH471091 Genomic DNA Translation: EAW77032.1
BC065930 mRNA Translation: AAH65930.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS5593.1

NCBI Reference Sequences

More...RefSeqi		NP_116325.1, NM_032936.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000257663.4; ENSP00000257663.3; ENSG00000135211.6

Database of genes from NCBI RefSeq genomes

More...GeneIDi		85025

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:85025

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000257663.4; ENSP00000257663.3; NM_032936.4; NP_116325.1

UCSC genome browser

More...UCSCi		uc003ugn.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF260336 mRNA Translation: AAG44667.1
AC004955 Genomic DNA Translation: AAP21882.1
AC004955 Genomic DNA Translation: AAP21883.1
CH236949 Genomic DNA Translation: EAL24196.1
CH471091 Genomic DNA Translation: EAW77032.1
BC065930 mRNA Translation: AAH65930.1 Different initiation.
CCDSiCCDS5593.1
RefSeqiNP_116325.1, NM_032936.3

3D structure databases

AlphaFoldDBiQ9H2L4
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...

Protein-protein interaction databases

BioGRIDi124434, 89 interactors
IntActiQ9H2L4, 96 interactors
STRINGi9606.ENSP00000257663

Protein family/group databases

TCDBi8.A.76.1.2, the tmem203 or pf14967 (tmem203) family

Genetic variation databases

BioMutaiTMEM60
DMDMi47605551

Proteomic databases

PaxDbiQ9H2L4
PRIDEiQ9H2L4
ProteomicsDBi80561

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		71000, 4 antibodies from 4 providers

The DNASU plasmid repository

More...DNASUi		85025

Genome annotation databases

EnsembliENST00000257663.4; ENSP00000257663.3; ENSG00000135211.6
GeneIDi85025
KEGGihsa:85025
MANE-SelectiENST00000257663.4; ENSP00000257663.3; NM_032936.4; NP_116325.1
UCSCiuc003ugn.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		85025
DisGeNETi85025

GeneCards: human genes, protein and diseases

More...GeneCardsi		TMEM60
HGNCiHGNC:21754, TMEM60
HPAiENSG00000135211, Low tissue specificity
neXtProtiNX_Q9H2L4
OpenTargetsiENSG00000135211
PharmGKBiPA134910139
VEuPathDBiHostDB:ENSG00000135211

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3879, Eukaryota
GeneTreeiENSGT00390000007283
HOGENOMiCLU_152149_0_0_1
InParanoidiQ9H2L4
OMAiFIPLWLY
OrthoDBi1512798at2759
PhylomeDBiQ9H2L4
TreeFamiTF325897

Enzyme and pathway databases

PathwayCommonsiQ9H2L4
SignaLinkiQ9H2L4

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		85025, 14 hits in 1082 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		TMEM60, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		85025
PharosiQ9H2L4, Tdark

Protein Ontology

More...PROi		PR:Q9H2L4
RNActiQ9H2L4, protein

Gene expression databases

BgeeiENSG00000135211, Expressed in secondary oocyte and 213 other tissues
GenevisibleiQ9H2L4, HS

Family and domain databases

InterProiView protein in InterPro
IPR019396, TM_Fragile-X-F-assoc
PANTHERiPTHR13568, PTHR13568, 1 hit
PfamiView protein in Pfam
PF10269, Tmemb_185A, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTMM60_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H2L4
Secondary accession number(s): A4D1C3, Q86UM0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2001
Last modified: May 25, 2022
This is version 122 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
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