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Entry version 125 (13 Feb 2019)
Sequence version 4 (11 Jan 2011)
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Protein

Translation initiation factor IF-3, mitochondrial

Gene

MTIF3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ribosomal small subunit binding Source: BHF-UCL
  • ribosome binding Source: GO_Central
  • translation factor activity, RNA binding Source: BHF-UCL
  • translation initiation factor activity Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5368286 Mitochondrial translation initiation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Translation initiation factor IF-3, mitochondrial
Short name:
IF-3(Mt)
Short name:
IF-3Mt
Short name:
IF3(mt)
Short name:
IF3mt
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MTIF3
ORF Names:DC38
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000122033.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29788 MTIF3

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H2K0

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
219402

Open Targets

More...
OpenTargetsi
ENSG00000122033

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162396264

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MTIF3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
317373570

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 31MitochondrionAdd BLAST31
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000028003732 – 278Translation initiation factor IF-3, mitochondrialAdd BLAST247

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H2K0

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H2K0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H2K0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H2K0

PeptideAtlas

More...
PeptideAtlasi
Q9H2K0

PRoteomics IDEntifications database

More...
PRIDEi
Q9H2K0

ProteomicsDB human proteome resource

More...
ProteomicsDBi
80558

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H2K0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H2K0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000122033 Expressed in 199 organ(s), highest expression level in right atrium auricular region

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H2K0 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA039791

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
SIAH1Q8IUQ43EBI-3923617,EBI-747107

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
128525, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q9H2K0, 38 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000370508

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9H2K0

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9H2K0

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the IF-3 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IXD5 Eukaryota
COG0290 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000014424

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000264227

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG080563

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H2K0

KEGG Orthology (KO)

More...
KOi
K02520

Identification of Orthologs from Complete Genome Data

More...
OMAi
EPPEYQL

Database of Orthologous Groups

More...
OrthoDBi
970215at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H2K0

TreeFam database of animal gene trees

More...
TreeFami
TF332326

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.110.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036788 T_IF-3_C_sf
IPR036787 T_IF-3_N_sf
IPR001288 Translation_initiation_fac_3
IPR019815 Translation_initiation_fac_3_C
IPR019814 Translation_initiation_fac_3_N

The PANTHER Classification System

More...
PANTHERi
PTHR10938 PTHR10938, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00707 IF3_C, 1 hit
PF05198 IF3_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54364 SSF54364, 1 hit
SSF55200 SSF55200, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9H2K0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAALFLKRLT LQTVKSENSC IRCFGKHILQ KTAPAQLSPI ASAPRLSFLI
60 70 80 90 100
HAKAFSTAED TQNEGKKTKK NKTAFSNVGR KISQRVIHLF DEKGNDLGNM
110 120 130 140 150
HRANVIRLMD ERDLRLVQRN TSTEPAEYQL MTGLQILQER QRLREMEKAN
160 170 180 190 200
PKTGPTLRKE LILSSNIGQH DLDTKTKQIQ QWIKKKHLVQ ITIKKGKNVD
210 220 230 240 250
VSENEMEEIF HQILQTMPGI ATFSSRPQAV QGGKALMCVL RAFSKNEEKA
260 270
YKETQETQER DTLNKDHGND KESNVLHQ
Length:278
Mass (Da):31,725
Last modified:January 11, 2011 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE0CA6D5F547DD6E3
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH39599 differs from that shown. Reason: Frameshift at position 246.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03104568T → I1 PublicationCorresponds to variant dbSNP:rs17857314Ensembl.1
Natural variantiVAR_031046243F → L3 PublicationsCorresponds to variant dbSNP:rs1218825Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF410851 mRNA Translation: AAL04150.1
AF265440 mRNA Translation: AAG44698.1
AL137059 Genomic DNA No translation available.
BC039599 mRNA Translation: AAH39599.1 Frameshift.
BC046166 mRNA Translation: AAH46166.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9322.1

NCBI Reference Sequences

More...
RefSeqi
NP_001159733.1, NM_001166261.1
NP_001159734.1, NM_001166262.1
NP_001159735.1, NM_001166263.1
NP_690876.3, NM_152912.4
XP_006719834.1, XM_006719771.3
XP_006719835.1, XM_006719772.3
XP_011533259.1, XM_011534957.2
XP_011533260.1, XM_011534958.2
XP_011533261.1, XM_011534959.2
XP_011533262.1, XM_011534960.2
XP_011533263.1, XM_011534961.2
XP_011533264.1, XM_011534962.2
XP_011533265.1, XM_011534963.2
XP_016875906.1, XM_017020417.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.534582

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000381116; ENSP00000370508; ENSG00000122033
ENST00000381120; ENSP00000370512; ENSG00000122033
ENST00000405591; ENSP00000384659; ENSG00000122033

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
219402

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:219402

UCSC genome browser

More...
UCSCi
uc001urh.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF410851 mRNA Translation: AAL04150.1
AF265440 mRNA Translation: AAG44698.1
AL137059 Genomic DNA No translation available.
BC039599 mRNA Translation: AAH39599.1 Frameshift.
BC046166 mRNA Translation: AAH46166.1
CCDSiCCDS9322.1
RefSeqiNP_001159733.1, NM_001166261.1
NP_001159734.1, NM_001166262.1
NP_001159735.1, NM_001166263.1
NP_690876.3, NM_152912.4
XP_006719834.1, XM_006719771.3
XP_006719835.1, XM_006719772.3
XP_011533259.1, XM_011534957.2
XP_011533260.1, XM_011534958.2
XP_011533261.1, XM_011534959.2
XP_011533262.1, XM_011534960.2
XP_011533263.1, XM_011534961.2
XP_011533264.1, XM_011534962.2
XP_011533265.1, XM_011534963.2
XP_016875906.1, XM_017020417.1
UniGeneiHs.534582

3D structure databases

ProteinModelPortaliQ9H2K0
SMRiQ9H2K0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi128525, 5 interactors
IntActiQ9H2K0, 38 interactors
STRINGi9606.ENSP00000370508

PTM databases

iPTMnetiQ9H2K0
PhosphoSitePlusiQ9H2K0

Polymorphism and mutation databases

BioMutaiMTIF3
DMDMi317373570

Proteomic databases

EPDiQ9H2K0
jPOSTiQ9H2K0
MaxQBiQ9H2K0
PaxDbiQ9H2K0
PeptideAtlasiQ9H2K0
PRIDEiQ9H2K0
ProteomicsDBi80558

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
219402
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000381116; ENSP00000370508; ENSG00000122033
ENST00000381120; ENSP00000370512; ENSG00000122033
ENST00000405591; ENSP00000384659; ENSG00000122033
GeneIDi219402
KEGGihsa:219402
UCSCiuc001urh.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
219402
DisGeNETi219402
EuPathDBiHostDB:ENSG00000122033.14

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MTIF3

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0011193
HGNCiHGNC:29788 MTIF3
HPAiHPA039791
neXtProtiNX_Q9H2K0
OpenTargetsiENSG00000122033
PharmGKBiPA162396264

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IXD5 Eukaryota
COG0290 LUCA
GeneTreeiENSGT00390000014424
HOGENOMiHOG000264227
HOVERGENiHBG080563
InParanoidiQ9H2K0
KOiK02520
OMAiEPPEYQL
OrthoDBi970215at2759
PhylomeDBiQ9H2K0
TreeFamiTF332326

Enzyme and pathway databases

ReactomeiR-HSA-5368286 Mitochondrial translation initiation

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MTIF3 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
219402

Protein Ontology

More...
PROi
PR:Q9H2K0

Gene expression databases

BgeeiENSG00000122033 Expressed in 199 organ(s), highest expression level in right atrium auricular region
GenevisibleiQ9H2K0 HS

Family and domain databases

Gene3Di3.30.110.10, 1 hit
InterProiView protein in InterPro
IPR036788 T_IF-3_C_sf
IPR036787 T_IF-3_N_sf
IPR001288 Translation_initiation_fac_3
IPR019815 Translation_initiation_fac_3_C
IPR019814 Translation_initiation_fac_3_N
PANTHERiPTHR10938 PTHR10938, 1 hit
PfamiView protein in Pfam
PF00707 IF3_C, 1 hit
PF05198 IF3_N, 1 hit
SUPFAMiSSF54364 SSF54364, 1 hit
SSF55200 SSF55200, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIF3M_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H2K0
Secondary accession number(s): Q05BL8, Q5W0V0, Q86X68
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: January 11, 2011
Last modified: February 13, 2019
This is version 125 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 13
    Human chromosome 13: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. Translation initiation factors
    List of translation initiation factor entries
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