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Entry version 142 (29 Sep 2021)
Sequence version 1 (01 Mar 2001)
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Protein

Dendritic cell-specific transmembrane protein

Gene

DCSTAMP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDifferentiation, Immunity

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9H295

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-8874211, CREB3 factors activate genes

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.N.1.1.1, the osteoclast fusion complex (ofc) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dendritic cell-specific transmembrane protein
Short name:
DC-STAMP
Short name:
hDC-STAMP
Alternative name(s):
Dendrocyte-expressed seven transmembrane protein
IL-four-induced protein
Short name:
FIND
Transmembrane 7 superfamily member 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DCSTAMP
Synonyms:TM7SF4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:18549, DCSTAMP

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
605933, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H295

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000164935

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 34CytoplasmicSequence analysisAdd BLAST34
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei35 – 55HelicalSequence analysisAdd BLAST21
Topological domaini56 – 57ExtracellularSequence analysis2
Transmembranei58 – 78HelicalSequence analysisAdd BLAST21
Topological domaini79 – 97CytoplasmicSequence analysisAdd BLAST19
Transmembranei98 – 118HelicalSequence analysisAdd BLAST21
Topological domaini119 – 209ExtracellularSequence analysisAdd BLAST91
Transmembranei210 – 230HelicalSequence analysisAdd BLAST21
Topological domaini231 – 292CytoplasmicSequence analysisAdd BLAST62
Transmembranei293 – 313HelicalSequence analysisAdd BLAST21
Topological domaini314 – 376ExtracellularSequence analysisAdd BLAST63
Transmembranei377 – 397HelicalSequence analysisAdd BLAST21
Topological domaini398 – 470Cytoplasmic1 PublicationAdd BLAST73

Keywords - Cellular componenti

Cell membrane, Endoplasmic reticulum, Endosome, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
81501

Open Targets

More...
OpenTargetsi
ENSG00000164935

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134938623

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9H295, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
DCSTAMP

Domain mapping of disease mutations (DMDM)

More...
DMDMi
71153342

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000725841 – 470Dendritic cell-specific transmembrane proteinAdd BLAST470

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Glycosylated.By similarity

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H295

PeptideAtlas

More...
PeptideAtlasi
Q9H295

PRoteomics IDEntifications database

More...
PRIDEi
Q9H295

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
17984
80513 [Q9H295-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H295

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H295

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Preferentially expressed by dendritic cells (DCs). Detected in both immature and mature DCs. Highly expressed in lymph nodes, lung, kidney and liver. Expressed at lower levels in pancreas, bone marrow, spleen, leukocytes, in freshly isolated peripheral blood mononuclear cells (PBMC) and B-cells. Not expressed in freshly isolated monocytes.2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Constitutively expressed in dendritic cells from day 3-8 in culture.1 Publication

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Expression is down-regulated by dexamethasone and up-regulated by IL4/interleukin-4 in macrophages. Down-regulated in CD40L-activated dendritic cells.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164935, Expressed in amygdala and 98 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H295, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000164935, Group enriched (adipose tissue, lung)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer. Homodimer. Isoform 1 interacts (via the C-terminus cytoplasmic tail) with OS9 isoform 1 (via the C-terminus tail); the interaction induces DCSTAMP redistribution to the endoplasmic reticulum-Golgi intermediate compartment. Isoform 1 interacts (via the C-terminus cytoplasmic tail) with OS9 isoform 2 (via the C-terminus tail) (By similarity).

Interacts with CREB3.

By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
123504, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q9H295, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000297581

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9H295, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9H295

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Several domains are necessary for interacting with OS9. The region in the cytoplasmic tail that is necessary for interaction with OS9, is also required for its transport (By similarity).By similarity

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QWDQ, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153269

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_046145_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H295

Identification of Orthologs from Complete Genome Data

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OMAi
LISWNQT

Database of Orthologous Groups

More...
OrthoDBi
821078at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H295

TreeFam database of animal gene trees

More...
TreeFami
TF318254

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR012858, DC_STAMP-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07782, DC_STAMP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q9H295-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGIWTSGTDI FLSLWEIYVS PRSPGWMDFI QHLGVCCLVA LISVGLLSVA
60 70 80 90 100
ACWFLPSIIA AAASWIITCV LLCCSKHARC FILLVFLSCG LREGRNALIA
110 120 130 140 150
AGTGIVILGH VENIFHNFKG LLDGMTCNLR AKSFSIHFPL LKKYIEAIQW
160 170 180 190 200
IYGLATPLSV FDDLVSWNQT LAVSLFSPSH VLEAQLNDSK GEVLSVLYQM
210 220 230 240 250
ATTTEVLSSL GQKLLAFAGL SLVLLGTGLF MKRFLGPCGW KYENIYITRQ
260 270 280 290 300
FVQFDERERH QQRPCVLPLN KEERRKYVII PTFWPTPKER KNLGLFFLPI
310 320 330 340 350
LIHLCIWVLF AAVDYLLYRL IFSVSKQFQS LPGFEVHLKL HGEKQGTQDI
360 370 380 390 400
IHDSSFNISV FEPNCIPKPK FLLSETWVPL SVILLILVML GLLSSILMQL
410 420 430 440 450
KILVSASFYP SVERKRIQYL HAKLLKKRSK QPLGEVKRRL SLYLTKIHFW
460 470
LPVLKMIRKK QMDMASADKS
Length:470
Mass (Da):53,393
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEA2B858FD2C7560C
GO
Isoform 2 (identifier: Q9H295-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     277-283: YVIIPTF → FISGFQS
     284-470: Missing.

Show »
Length:283
Mass (Da):31,586
Checksum:i4BB890F27FBC9319
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti200M → R in AAI71732 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_051438349D → G. Corresponds to variant dbSNP:rs3802204Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_044787277 – 283YVIIPTF → FISGFQS in isoform 2. 1 Publication7
Alternative sequenceiVSP_044788284 – 470Missing in isoform 2. 1 PublicationAdd BLAST187

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF305068 mRNA Translation: AAG39167.1
AF277290 mRNA Translation: AAL02152.1
AP003471 Genomic DNA No translation available.
BC069349 mRNA Translation: AAH69349.1
BC112018 mRNA Translation: AAI12019.1
BC112020 mRNA Translation: AAI12021.1
BC171732 mRNA Translation: AAI71732.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS59111.1 [Q9H295-2]
CCDS6301.1 [Q9H295-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001244246.1, NM_001257317.1 [Q9H295-2]
NP_110415.1, NM_030788.3 [Q9H295-1]
XP_011515623.1, XM_011517321.1 [Q9H295-1]
XP_011515626.1, XM_011517324.1 [Q9H295-2]
XP_016869367.1, XM_017013878.1
XP_016869369.1, XM_017013880.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000297581; ENSP00000297581; ENSG00000164935 [Q9H295-1]
ENST00000517991; ENSP00000428869; ENSG00000164935 [Q9H295-2]
ENST00000622554; ENSP00000480546; ENSG00000164935 [Q9H295-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
81501

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:81501

UCSC genome browser

More...
UCSCi
uc003ylx.3, human [Q9H295-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF305068 mRNA Translation: AAG39167.1
AF277290 mRNA Translation: AAL02152.1
AP003471 Genomic DNA No translation available.
BC069349 mRNA Translation: AAH69349.1
BC112018 mRNA Translation: AAI12019.1
BC112020 mRNA Translation: AAI12021.1
BC171732 mRNA Translation: AAI71732.1
CCDSiCCDS59111.1 [Q9H295-2]
CCDS6301.1 [Q9H295-1]
RefSeqiNP_001244246.1, NM_001257317.1 [Q9H295-2]
NP_110415.1, NM_030788.3 [Q9H295-1]
XP_011515623.1, XM_011517321.1 [Q9H295-1]
XP_011515626.1, XM_011517324.1 [Q9H295-2]
XP_016869367.1, XM_017013878.1
XP_016869369.1, XM_017013880.1

3D structure databases

SMRiQ9H295
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi123504, 1 interactor
IntActiQ9H295, 1 interactor
STRINGi9606.ENSP00000297581

Protein family/group databases

TCDBi1.N.1.1.1, the osteoclast fusion complex (ofc) family

PTM databases

iPTMnetiQ9H295
PhosphoSitePlusiQ9H295

Genetic variation databases

BioMutaiDCSTAMP
DMDMi71153342

Proteomic databases

PaxDbiQ9H295
PeptideAtlasiQ9H295
PRIDEiQ9H295
ProteomicsDBi17984
80513 [Q9H295-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
42882, 85 antibodies

The DNASU plasmid repository

More...
DNASUi
81501

Genome annotation databases

EnsembliENST00000297581; ENSP00000297581; ENSG00000164935 [Q9H295-1]
ENST00000517991; ENSP00000428869; ENSG00000164935 [Q9H295-2]
ENST00000622554; ENSP00000480546; ENSG00000164935 [Q9H295-2]
GeneIDi81501
KEGGihsa:81501
UCSCiuc003ylx.3, human [Q9H295-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
81501
DisGeNETi81501

GeneCards: human genes, protein and diseases

More...
GeneCardsi
DCSTAMP
HGNCiHGNC:18549, DCSTAMP
HPAiENSG00000164935, Group enriched (adipose tissue, lung)
MIMi605933, gene
neXtProtiNX_Q9H295
OpenTargetsiENSG00000164935
PharmGKBiPA134938623
VEuPathDBiHostDB:ENSG00000164935

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG502QWDQ, Eukaryota
GeneTreeiENSGT00940000153269
HOGENOMiCLU_046145_0_0_1
InParanoidiQ9H295
OMAiLISWNQT
OrthoDBi821078at2759
PhylomeDBiQ9H295
TreeFamiTF318254

Enzyme and pathway databases

PathwayCommonsiQ9H295
ReactomeiR-HSA-8874211, CREB3 factors activate genes

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
81501, 3 hits in 1004 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
81501
PharosiQ9H295, Tbio

Protein Ontology

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PROi
PR:Q9H295
RNActiQ9H295, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000164935, Expressed in amygdala and 98 other tissues
GenevisibleiQ9H295, HS

Family and domain databases

InterProiView protein in InterPro
IPR012858, DC_STAMP-like
PfamiView protein in Pfam
PF07782, DC_STAMP, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDCSTP_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H295
Secondary accession number(s): B7ZVW2, E7ESG0, Q2M2D5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: March 1, 2001
Last modified: September 29, 2021
This is version 142 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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