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Entry version 141 (22 Apr 2020)
Sequence version 1 (01 Mar 2001)
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Protein

Adenosine 3'-phospho 5'-phosphosulfate transporter 2

Gene

SLC35B3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon.1 Publication

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=2.2 µM for PAPS1 Publication

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Biological processTransport

    Enzyme and pathway databases

    Reactome - a knowledgebase of biological pathways and processes

    More...
    Reactomei
    R-HSA-174362 Transport and synthesis of PAPS
    R-HSA-727802 Transport of nucleotide sugars

    Protein family/group databases

    Transport Classification Database

    More...
    TCDBi
    2.A.7.11.5 the drug/metabolite transporter (dmt) superfamily

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Adenosine 3'-phospho 5'-phosphosulfate transporter 2
    Alternative name(s):
    3'-phosphoadenosine 5'-phosphosulfate transporter
    PAPS transporter 2
    Solute carrier family 35 member B3
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:SLC35B3
    Synonyms:C6orf196, PAPST2
    ORF Names:CGI-19
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

    Organism-specific databases

    Human Gene Nomenclature Database

    More...
    HGNCi
    HGNC:21601 SLC35B3

    Online Mendelian Inheritance in Man (OMIM)

    More...
    MIMi
    610845 gene

    neXtProt; the human protein knowledge platform

    More...
    neXtProti
    NX_Q9H1N7

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
    Transmembranei114 – 134HelicalSequence analysisAdd BLAST21
    Transmembranei147 – 167HelicalSequence analysisAdd BLAST21
    Transmembranei170 – 190HelicalSequence analysisAdd BLAST21
    Transmembranei196 – 216HelicalSequence analysisAdd BLAST21
    Transmembranei223 – 243HelicalSequence analysisAdd BLAST21
    Transmembranei267 – 287HelicalSequence analysisAdd BLAST21
    Transmembranei298 – 317HelicalSequence analysisAdd BLAST20
    Transmembranei324 – 346HelicalSequence analysisAdd BLAST23
    Transmembranei349 – 369HelicalSequence analysisAdd BLAST21

    Keywords - Cellular componenti

    Golgi apparatus, Membrane

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    Organism-specific databases

    DisGeNET

    More...
    DisGeNETi
    51000

    Open Targets

    More...
    OpenTargetsi
    ENSG00000124786

    The Pharmacogenetics and Pharmacogenomics Knowledge Base

    More...
    PharmGKBi
    PA134889889

    Miscellaneous databases

    Pharos NIH Druggable Genome Knowledgebase

    More...
    Pharosi
    Q9H1N7 Tdark

    Polymorphism and mutation databases

    BioMuta curated single-nucleotide variation and disease association database

    More...
    BioMutai
    SLC35B3

    Domain mapping of disease mutations (DMDM)

    More...
    DMDMi
    74752580

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002133791 – 401Adenosine 3'-phospho 5'-phosphosulfate transporter 2Add BLAST401

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi12N-linked (GlcNAc...) asparagineSequence analysis1
    Glycosylationi71N-linked (GlcNAc...) asparagineSequence analysis1
    Glycosylationi254N-linked (GlcNAc...) asparagineSequence analysis1

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    Encyclopedia of Proteome Dynamics

    More...
    EPDi
    Q9H1N7

    jPOST - Japan Proteome Standard Repository/Database

    More...
    jPOSTi
    Q9H1N7

    MassIVE - Mass Spectrometry Interactive Virtual Environment

    More...
    MassIVEi
    Q9H1N7

    MaxQB - The MaxQuant DataBase

    More...
    MaxQBi
    Q9H1N7

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q9H1N7

    PeptideAtlas

    More...
    PeptideAtlasi
    Q9H1N7

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q9H1N7

    ProteomicsDB: a multi-organism proteome resource

    More...
    ProteomicsDBi
    80431 [Q9H1N7-1]
    80432 [Q9H1N7-2]
    80433 [Q9H1N7-3]

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...
    iPTMneti
    Q9H1N7

    Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

    More...
    PhosphoSitePlusi
    Q9H1N7

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Preferentially and highly expressed in colon.1 Publication

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...
    Bgeei
    ENSG00000124786 Expressed in tibia and 201 other tissues

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    Q9H1N7 baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    Q9H1N7 HS

    Organism-specific databases

    Human Protein Atlas

    More...
    HPAi
    ENSG00000124786 Low tissue specificity

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGrid)

    More...
    BioGridi
    119208, 3 interactors

    Protein interaction database and analysis system

    More...
    IntActi
    Q9H1N7, 1 interactor

    STRING: functional protein association networks

    More...
    STRINGi
    9606.ENSP00000368981

    Miscellaneous databases

    RNAct, Protein-RNA interaction predictions for model organisms.

    More...
    RNActi
    Q9H1N7 protein

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG1582 Eukaryota
    COG0697 LUCA

    Ensembl GeneTree

    More...
    GeneTreei
    ENSGT00940000157040

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    CLU_036019_2_0_1

    KEGG Orthology (KO)

    More...
    KOi
    K15277

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    YNRTTQF

    Database of Orthologous Groups

    More...
    OrthoDBi
    1116466at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q9H1N7

    TreeFam database of animal gene trees

    More...
    TreeFami
    TF314523

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR013657 UAA

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF08449 UAA, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

    This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

    Isoform 1 (identifier: Q9H1N7-1) [UniParc]FASTAAdd to basket

    This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide
            10         20         30         40         50
    MDLTQQAKDI QNITVQETNK NNSESIECSK ITMDLKFNNS RKYISITVPS
    60 70 80 90 100
    KTQTMSPHIK SVDDVVVLGM NLSKFNKLTQ FFICVAGVFV FYLIYGYLQE
    110 120 130 140 150
    LIFSVEGFKS CGWYLTLVQF AFYSIFGLIE LQLIQDKRRR IPGKTYMIIA
    160 170 180 190 200
    FLTVGTMGLS NTSLGYLNYP TQVIFKCCKL IPVMLGGVFI QGKRYNVADV
    210 220 230 240 250
    SAAICMSLGL IWFTLADSTT APNFNLTGVV LISLALCADA VIGNVQEKAM
    260 270 280 290 300
    KLHNASNSEM VLYSYSIGFV YILLGLTCTS GLGPAVTFCA KNPVRTYGYA
    310 320 330 340 350
    FLFSLTGYFG ISFVLALIKI FGALIAVTVT TGRKAMTIVL SFIFFAKPFT
    360 370 380 390 400
    FQYVWSGLLV VLGIFLNVYS KNMDKIRLPS LYDLINKSVE ARKSRTLAQT

    V
    Length:401
    Mass (Da):44,593
    Last modified:March 1, 2001 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2582EFD45ECA842C
    GO
    Isoform 2 (identifier: Q9H1N7-2) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         141-153: IPGKTYMIIAFLT → YVVCFYFLIFHLY
         154-401: Missing.

    Show »
    Length:153
    Mass (Da):17,914
    Checksum:iAEF35780DBBDA8E2
    GO
    Isoform 3 (identifier: Q9H1N7-3) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         261-283: VLYSYSIGFVYILLGLTCTSGLG → NITTSSYSGVFIFPNKLKIPLVL
         284-401: Missing.

    Show »
    Length:283
    Mass (Da):31,531
    Checksum:i7A9DF4B6ACC02E39
    GO

    <p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

    There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
    EntryEntry nameProtein names
    Gene namesLengthAnnotation
    A0A024QZW4A0A024QZW4_HUMAN
    Adenosine 3'-phospho 5'-phosphosulf...
    SLC35B3 hCG_14673
    369Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    A0A3B3IRN3A0A3B3IRN3_HUMAN
    Adenosine 3'-phospho 5'-phosphosulf...
    SLC35B3
    251Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

    <p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

    The sequence AAD27728 differs from that shown. Reason: Frameshift.Curated
    The sequence CAE46041 differs from that shown. Reason: Erroneous initiation.Curated

    Alternative sequence

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_016193141 – 153IPGKT…IAFLT → YVVCFYFLIFHLY in isoform 2. 1 PublicationAdd BLAST13
    Alternative sequenceiVSP_016194154 – 401Missing in isoform 2. 1 PublicationAdd BLAST248
    Alternative sequenceiVSP_016195261 – 283VLYSY…TSGLG → NITTSSYSGVFIFPNKLKIP LVL in isoform 3. 1 PublicationAdd BLAST23
    Alternative sequenceiVSP_016196284 – 401Missing in isoform 3. 1 PublicationAdd BLAST118

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AB231931 mRNA Translation: BAE93015.1
    AF132953 mRNA Translation: AAD27728.1 Frameshift.
    BX538271 mRNA Translation: CAD98078.1
    BX641086 mRNA Translation: CAE46041.1 Different initiation.
    AL355815 Genomic DNA No translation available.
    BC006973 mRNA Translation: AAH06973.1

    The Consensus CDS (CCDS) project

    More...
    CCDSi
    CCDS4508.1 [Q9H1N7-1]

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_001136013.1, NM_001142541.2 [Q9H1N7-1]
    NP_057032.2, NM_015948.4 [Q9H1N7-1]
    XP_005249214.1, XM_005249157.2
    XP_006715165.1, XM_006715102.3
    XP_016866399.1, XM_017010910.1 [Q9H1N7-1]
    XP_016866400.1, XM_017010911.1 [Q9H1N7-1]

    Genome annotation databases

    Ensembl eukaryotic genome annotation project

    More...
    Ensembli
    ENST00000379660; ENSP00000368981; ENSG00000124786 [Q9H1N7-1]
    ENST00000644923; ENSP00000496368; ENSG00000124786 [Q9H1N7-1]
    ENST00000648867; ENSP00000497645; ENSG00000124786 [Q9H1N7-3]

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    51000

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    hsa:51000

    UCSC genome browser

    More...
    UCSCi
    uc003myb.5 human [Q9H1N7-1]

    Keywords - Coding sequence diversityi

    Alternative splicing

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AB231931 mRNA Translation: BAE93015.1
    AF132953 mRNA Translation: AAD27728.1 Frameshift.
    BX538271 mRNA Translation: CAD98078.1
    BX641086 mRNA Translation: CAE46041.1 Different initiation.
    AL355815 Genomic DNA No translation available.
    BC006973 mRNA Translation: AAH06973.1
    CCDSiCCDS4508.1 [Q9H1N7-1]
    RefSeqiNP_001136013.1, NM_001142541.2 [Q9H1N7-1]
    NP_057032.2, NM_015948.4 [Q9H1N7-1]
    XP_005249214.1, XM_005249157.2
    XP_006715165.1, XM_006715102.3
    XP_016866399.1, XM_017010910.1 [Q9H1N7-1]
    XP_016866400.1, XM_017010911.1 [Q9H1N7-1]

    3D structure databases

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    SWISS-MODEL Interactive Workspace

    More...
    SWISS-MODEL-Workspacei
    Submit a new modelling project...

    Protein-protein interaction databases

    BioGridi119208, 3 interactors
    IntActiQ9H1N7, 1 interactor
    STRINGi9606.ENSP00000368981

    Protein family/group databases

    TCDBi2.A.7.11.5 the drug/metabolite transporter (dmt) superfamily

    PTM databases

    iPTMnetiQ9H1N7
    PhosphoSitePlusiQ9H1N7

    Polymorphism and mutation databases

    BioMutaiSLC35B3
    DMDMi74752580

    Proteomic databases

    EPDiQ9H1N7
    jPOSTiQ9H1N7
    MassIVEiQ9H1N7
    MaxQBiQ9H1N7
    PaxDbiQ9H1N7
    PeptideAtlasiQ9H1N7
    PRIDEiQ9H1N7
    ProteomicsDBi80431 [Q9H1N7-1]
    80432 [Q9H1N7-2]
    80433 [Q9H1N7-3]

    Protocols and materials databases

    Antibodypedia a portal for validated antibodies

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    Antibodypediai
    24732 9 antibodies

    The DNASU plasmid repository

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    DNASUi
    51000

    Genome annotation databases

    EnsembliENST00000379660; ENSP00000368981; ENSG00000124786 [Q9H1N7-1]
    ENST00000644923; ENSP00000496368; ENSG00000124786 [Q9H1N7-1]
    ENST00000648867; ENSP00000497645; ENSG00000124786 [Q9H1N7-3]
    GeneIDi51000
    KEGGihsa:51000
    UCSCiuc003myb.5 human [Q9H1N7-1]

    Organism-specific databases

    Comparative Toxicogenomics Database

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    CTDi
    51000
    DisGeNETi51000

    GeneCards: human genes, protein and diseases

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    GeneCardsi
    SLC35B3
    HGNCiHGNC:21601 SLC35B3
    HPAiENSG00000124786 Low tissue specificity
    MIMi610845 gene
    neXtProtiNX_Q9H1N7
    OpenTargetsiENSG00000124786
    PharmGKBiPA134889889

    GenAtlas: human gene database

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    GenAtlasi
    Search...

    Phylogenomic databases

    eggNOGiKOG1582 Eukaryota
    COG0697 LUCA
    GeneTreeiENSGT00940000157040
    HOGENOMiCLU_036019_2_0_1
    KOiK15277
    OMAiYNRTTQF
    OrthoDBi1116466at2759
    PhylomeDBiQ9H1N7
    TreeFamiTF314523

    Enzyme and pathway databases

    ReactomeiR-HSA-174362 Transport and synthesis of PAPS
    R-HSA-727802 Transport of nucleotide sugars

    Miscellaneous databases

    ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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    ChiTaRSi
    SLC35B3 human

    Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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    GenomeRNAii
    51000
    PharosiQ9H1N7 Tdark

    Protein Ontology

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    PROi
    PR:Q9H1N7
    RNActiQ9H1N7 protein

    The Stanford Online Universal Resource for Clones and ESTs

    More...
    SOURCEi
    Search...

    Gene expression databases

    BgeeiENSG00000124786 Expressed in tibia and 201 other tissues
    ExpressionAtlasiQ9H1N7 baseline and differential
    GenevisibleiQ9H1N7 HS

    Family and domain databases

    InterProiView protein in InterPro
    IPR013657 UAA
    PfamiView protein in Pfam
    PF08449 UAA, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

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    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS35B3_HUMAN
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H1N7
    Secondary accession number(s): A6NKX9
    , Q1XH11, Q6MZJ0, Q7Z662, Q9Y308
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
    Last sequence update: March 1, 2001
    Last modified: April 22, 2020
    This is version 141 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. Human chromosome 6
      Human chromosome 6: entries, gene names and cross-references to MIM
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